'
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc gluconate)
50 mg
455%

Top Medical Research Studies

8
Zinc nanoparticle aids gout treatment
A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway.
Direct focus on zinc treatment.
We investigated how zinc, specifically in the form of zinc ferrite nanoparticles (ZFN), can impact gouty arthritis. The research focused on finding a safe and effective treatment option to help people dealing with this painful condition, which often affects various age groups.

To explore this, we created ZFN, which has notable activities that help combat inflammation and oxidative stress, while also being gentle on the body. What’s interesting about ZFN is that its low zinc content helps avoid some of the common issues with other zinc-based treatments, such as toxicity. We tested ZFN through both laboratory studies and real-life models to see its effectiveness fully.

Our results were promising! We observed that ZFN significantly reduced inflammation and oxidative stress associated with gout. It seems to work by influencing important body pathways, particularly weakening signals that promote inflammation while boosting the body's natural defenses. This modulation signifies a powerful method for treating gout without the heavy side effects of current medications.

The discoveries we made in this study not only highlight a new potential treatment for gouty arthritis but also demonstrate the wider applicability of nanotechnology in health. The protective benefits of ZFN pave the way for more developments in treating inflammatory conditions like gout.
Read More
8
Zinc's role in gout management
Compounds containing trace element copper or zinc exhibit as potent hyperuricemia inhibitors via xanthine oxidase inactivation.
Zinc's effects assessed for gout
We investigated the possible benefits of zinc in treating gout and hyperuricemia, focusing on how it affects xanthine oxidase (XOD), a key enzyme involved in uric acid production. The study synthesized two compounds—one incorporating copper and the other zinc—both of which demonstrated the ability to inhibit XOD effectively.

Through various experiments, we observed that these compounds not only decreased uric acid levels in hyperuricemia-induced mice but also exhibited minimal adverse effects on kidney function. This is promising news for those suffering from gout, as elevated uric acid levels can lead to painful flare-ups.

Particularly, zinc’s contribution was noted as significant when it came to enhancing the efficacy of the treatment. By suppressing XOD activation, the compounds helped in lowering serum uric acid levels, suggesting that zinc plays a beneficial role alongside other compounds in managing gout symptoms.

Overall, our findings support the idea that compounds containing trace elements like zinc can be a valid approach in addressing gout, ushering in new treatment perspectives for better management of the condition.
Read More
8
Zinc aids in gout management
Folic acid and zinc improve hyperuricemia by altering the gut microbiota of rats with high-purine diet-induced hyperuricemia.
Zinc's effects on gout remain unclear
We explored how zinc and folic acid can potentially improve hyperuricemia, a condition that can lead to gout, through their influence on gut bacteria. In our study, we established a model of hyperuricemia in rats by feeding them a high-purine diet.

We observed that treatment with zinc and folic acid resulted in noticeably lower uric acid levels, which is a crucial factor in gout development. Additionally, these treatments decreased the activity of key enzymes associated with uric acid production, promoting healthier uric acid levels.

Our research utilized advanced sequencing technology to analyze the gut microbiota, revealing that zinc and folic acid enhanced beneficial bacteria while reducing harmful strains. This shift in gut composition is important because it plays a role in maintaining intestine health, which can influence uric acid metabolism.

Ultimately, we found that zinc, alongside folic acid, shows promise as a safe and effective approach to managing hyperuricemia and gout. This dual therapy could offer hope for those suffering from these conditions, emphasizing the importance of gut health in overall metabolic processes.
Read More

Most Useful Reviews

8.8
Minor improvements noted
Once again, Solgar impresses with its quality. The distinctive brown glass jars with gold lids contain zinc in a therapeutic dosage of 50 mg, purchased for treating gout and psoriasis. My doctor suggested the dosage due to zinc deficiency. It is recommended to take it with food and plenty of water. There are no side effects, and I have noticed minor improvements. I hope for a long-term quality remission regarding my ailments. I would recommend this product.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
8
Zinc nanoparticle aids gout treatment
A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway.
Direct focus on zinc treatment.
We investigated how zinc, specifically in the form of zinc ferrite nanoparticles (ZFN), can impact gouty arthritis. The research focused on finding a safe and effective treatment option to help people dealing with this painful condition, which often affects various age groups.

To explore this, we created ZFN, which has notable activities that help combat inflammation and oxidative stress, while also being gentle on the body. What’s interesting about ZFN is that its low zinc content helps avoid some of the common issues with other zinc-based treatments, such as toxicity. We tested ZFN through both laboratory studies and real-life models to see its effectiveness fully.

Our results were promising! We observed that ZFN significantly reduced inflammation and oxidative stress associated with gout. It seems to work by influencing important body pathways, particularly weakening signals that promote inflammation while boosting the body's natural defenses. This modulation signifies a powerful method for treating gout without the heavy side effects of current medications.

The discoveries we made in this study not only highlight a new potential treatment for gouty arthritis but also demonstrate the wider applicability of nanotechnology in health. The protective benefits of ZFN pave the way for more developments in treating inflammatory conditions like gout.
Read More
8
Zinc aids in gout management
Folic acid and zinc improve hyperuricemia by altering the gut microbiota of rats with high-purine diet-induced hyperuricemia.
Zinc's effects on gout remain unclear
We explored how zinc and folic acid can potentially improve hyperuricemia, a condition that can lead to gout, through their influence on gut bacteria. In our study, we established a model of hyperuricemia in rats by feeding them a high-purine diet.

We observed that treatment with zinc and folic acid resulted in noticeably lower uric acid levels, which is a crucial factor in gout development. Additionally, these treatments decreased the activity of key enzymes associated with uric acid production, promoting healthier uric acid levels.

Our research utilized advanced sequencing technology to analyze the gut microbiota, revealing that zinc and folic acid enhanced beneficial bacteria while reducing harmful strains. This shift in gut composition is important because it plays a role in maintaining intestine health, which can influence uric acid metabolism.

Ultimately, we found that zinc, alongside folic acid, shows promise as a safe and effective approach to managing hyperuricemia and gout. This dual therapy could offer hope for those suffering from these conditions, emphasizing the importance of gut health in overall metabolic processes.
Read More
8
Zinc's role in gout management
Compounds containing trace element copper or zinc exhibit as potent hyperuricemia inhibitors via xanthine oxidase inactivation.
Zinc's effects assessed for gout
We investigated the possible benefits of zinc in treating gout and hyperuricemia, focusing on how it affects xanthine oxidase (XOD), a key enzyme involved in uric acid production. The study synthesized two compounds—one incorporating copper and the other zinc—both of which demonstrated the ability to inhibit XOD effectively.

Through various experiments, we observed that these compounds not only decreased uric acid levels in hyperuricemia-induced mice but also exhibited minimal adverse effects on kidney function. This is promising news for those suffering from gout, as elevated uric acid levels can lead to painful flare-ups.

Particularly, zinc’s contribution was noted as significant when it came to enhancing the efficacy of the treatment. By suppressing XOD activation, the compounds helped in lowering serum uric acid levels, suggesting that zinc plays a beneficial role alongside other compounds in managing gout symptoms.

Overall, our findings support the idea that compounds containing trace elements like zinc can be a valid approach in addressing gout, ushering in new treatment perspectives for better management of the condition.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Minor improvements noted
Once again, Solgar impresses with its quality. The distinctive brown glass jars with gold lids contain zinc in a therapeutic dosage of 50 mg, purchased for treating gout and psoriasis. My doctor suggested the dosage due to zinc deficiency. It is recommended to take it with food and plenty of water. There are no side effects, and I have noticed minor improvements. I hope for a long-term quality remission regarding my ailments. I would recommend this product.
Read More
image