We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
Read More
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
Read More
9
Zinc compounds as acne treatment
Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations.
We examined the potential of zinc compounds, particularly zinc-amino acid complexes, to effectively treat acne. This study focused on how these zinc formulations could not only help with acne but also ensure safety for the skin.
Initially, we checked the cytotoxicity of the zinc complexes on human skin cells, demonstrating their safety. We then evaluated their antibacterial properties, which are crucial for combating acne-causing bacteria. After finding promising results, we selected zinc complexes with glycine and histidine to create unique gel formulations.
The next steps involved thorough testing of these gel preparations for stability, purity, and tolerability. We confirmed that they maintained their quality over time, showed no irritation or allergic reactions in a patch test with 25 volunteers, and exhibited high microbiological purity.
Ultimately, our findings suggest that these zinc-based gels can be a valuable topical option for acne treatment due to their strong antibacterial performance and minimal toxicity to skin cells. Our dermatological formulations appear safe and effective, contributing positively to acne management.
Read More
Most Useful Reviews
9
Clearer skin
530 people found this helpful
Zinc is essential for improving immunity, especially in autumn and winter. I combined it with selenium and noticed significant skin improvements after two months. My skin became cleaner and less oily in the T-zone, and I no longer needed foundation to cover acne and blemishes. I had no side effects from this zinc, as long as I took it after meals. Highly recommend it for your skin and nails!
Read More
8
Improved immunity
491 people found this helpful
Solgar is a reputable brand, crucial for addressing zinc deficiency, which can lead to various health issues. Symptoms like frequent illness and skin conditions suggest zinc deficiency. I urge everyone to take zinc for better health. A healthy body should prioritize zinc!
Read More
8
Reduced inflammation
338 people found this helpful
Solgar's zinc is a staple for me. It doesn’t cause nausea or bloating, and I take it at night after meals. Zinc has helped heal mucous membranes and clears up acne, controlling oily skin. The tiny tablets are easy to take, and I've noticed the positive changes in my skin health!
We investigated the effectiveness of a novel microneedle patch designed for acne treatment, which incorporates zinc-based nanoparticles. This patch combines sodium hyaluronate with zinc porphyrin-based metal-organic frameworks and zinc oxide. By using ultrasound to release activated oxygen, we observed a remarkable antibacterial efficiency, achieving a 99.73% reduction in acne-causing bacteria within just 15 minutes.
Zinc plays a crucial role in this innovative approach. Not only does it help eliminate harmful bacteria, but it also appears to enhance skin health. The presence of zinc ions promotes the up-regulation of genes associated with DNA replication, which supports the growth of fibroblasts. This is a vital process for skin repair and rejuvenation, showing that zinc can potentially contribute to both the treatment and recovery of acne-affected skin.
Overall, our findings suggest that this microneedle patch, which utilizes zinc and ultrasound-responsive technology, represents a promising strategy for effectively managing acne without relying on traditional antibiotics.
We investigated how zinc treatment affects acne, particularly focusing on its potential benefits for those suffering from acne rosacea. The study observed that zinc sulfate solution at a concentration of 5% played a notable role in reducing the severity of acne rosacea symptoms.
Findings indicated that around 40% to 60% of patients experienced a moderate to good response after using zinc. This suggests that zinc could be helpful for individuals looking for alternatives or supplements in their acne treatment regimen.
However, it's important to acknowledge that while zinc showed positive results, the isolated effect of zinc alone cannot be fully determined. It might have worked in conjunction with other treatment factors, which complicates our understanding of its effectiveness.
Therefore, we emphasize the need for further studies to clarify exactly how zinc contributes to acne treatment outcomes and to evaluate its role alongside other therapies.
Read More
9
Zinc oxide nanoparticles combat acne
Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using and Its Effect on Acne Vulgaris.
We assessed the potential of zinc oxide nanoparticles in combating acne. Using biogenically synthesized zinc oxide, we mixed it with a polymer to create a topical nanogel aimed at treating acne. Through rigorous testing against acne-causing bacteria, we observed that these biogenic nanoparticles showed a promising antibacterial effect, particularly against Gram-positive bacteria.
Notably, the particle size of our biogenic zinc oxide nanoparticles measured around 20 nm, indicating a high degree of purity. When pitted against chemogenic counterparts, the biogenic version proved to be more effective. This suggests that zinc oxide, especially when produced biogenically, could be a valuable addition to skincare products targeting acne.
Moreover, the study highlights the environment-friendly aspect of using biogenic zinc oxide in skincare formulations, making it a preferable choice for those concerned about sustainability. Our findings suggest that these hybrid nanogels could serve as an effective solution against skin infections associated with acne, adding to their appeal in modern skincare.
Read More
9
Zinc gel shows promise for acne
Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study.
We wanted to find out how effective a cleansing gel containing salicylic acid, zinc gluconate, and lipohydroxy acids is for treating truncal acne. Conducted over 84 days, our study included 51 individuals with mild to moderate acne, and we tracked various skin conditions like the number of acne lesions and the overall skin barrier health.
After regular use of the gel, we observed a significant reduction in total acne lesions—over half were improved by the end of the study. While non-inflammatory lesions saw a drop of 64% and inflammatory lesions were reduced by nearly 30%, the key point is that zinc gluconate was part of a trio of ingredients, making it challenging to pinpoint its specific contribution.
When we considered skin barrier function, a notable improvement was also measured—21.26% better at Day 84. Patients reported no significant side effects or intolerances, suggesting that the ingredients within the gel, including zinc, were well tolerated.
Overall, the evidence hints at zinc's potential benefits as part of a combination treatment against acne. But since it was used together with other active ingredients, we can't solely credit zinc for the results observed.
Read More
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
Zinc is essential for improving immunity, especially in autumn and winter. I combined it with selenium and noticed significant skin improvements after two months. My skin became cleaner and less oily in the T-zone, and I no longer needed foundation to cover acne and blemishes. I had no side effects from this zinc, as long as I took it after meals. Highly recommend it for your skin and nails!
Read More
8
Improved immunity
491 people found this helpful
Solgar is a reputable brand, crucial for addressing zinc deficiency, which can lead to various health issues. Symptoms like frequent illness and skin conditions suggest zinc deficiency. I urge everyone to take zinc for better health. A healthy body should prioritize zinc!
Read More
8
Reduced inflammation
338 people found this helpful
Solgar's zinc is a staple for me. It doesn’t cause nausea or bloating, and I take it at night after meals. Zinc has helped heal mucous membranes and clears up acne, controlling oily skin. The tiny tablets are easy to take, and I've noticed the positive changes in my skin health!
Read More
9
Acne relief
297 people found this helpful
After struggling with rashes on my cheeks for a year, zinc transformed my skin. Within a week of use, new acne stopped appearing. Now I use it as needed during menstruation. The results have been remarkable!
Read More
10
Clearer complexion
166 people found this helpful
Zinc is vital for boosting immunity and improving skin health. After taking it for a month and a half, my acne cleared up, my hair stopped shedding, and I regained my sense of smell post-COVID. It has worked wonders for me!
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been recognized for its potential benefits in managing acne due to its anti-inflammatory properties and ability to reduce oil production in the skin. Several studies suggest that zinc supplements may help decrease the severity of acne lesions and improve overall skin health. Additionally, zinc plays a crucial role in the immune system, which can be beneficial in fighting off the bacteria that contribute to acne breakouts. For individuals struggling with moderate acne, opting for zinc supplements or using topical treatments containing zinc might offer some relief and improvement.
That said, while zinc can assist in managing acne, it is not a standalone solution, and results can vary. It’s important to combine any zinc treatment with a comprehensive skincare routine tailored to your skin type and acne severity. Consulting a dermatologist before starting any new supplement or treatment is wise, as they can offer personalized advice and the most effective treatment options for your specific situation.
Based on user reviews, the timeline to see results from taking zinc supplements for acne varies but typically ranges from one week to two months. Several users reported significant improvements within just a week; for example, one reviewer mentioned that their acne began to clear up after only a week of use Read Review. Another reviewer echoed similar results, noting that their daughter experienced noticeable changes in her skin within the first week Read Review.
On the other hand, some users found more gradual improvements, with noticeable results appearing after one to two months of consistent use. For instance, one individual observed their skin becoming clearer and more elastic over a two-month period Read Review. Other reports suggest that keeping up with the supplement over a month and a half led to significant control over acne and overall skin health Read Review. Therefore, if you're considering zinc for acne, be patient and monitor your skin's response over these timeframes.
Recent scientific studies suggest that zinc can play a significant role in the management of acne. A high-dose zinc treatment showed promising results in reducing inflammation associated with acne when tested in a mouse model, indicating a potential new therapeutic avenue for those struggling with this skin condition [1]. Furthermore, a systematic review of zinc treatments found that patients often exhibited a notable reduction in acne lesions, particularly inflammatory ones, when treated with zinc [16]. This aligns with findings from other studies where zinc sulfate was highlighted as effective, especially for acne rosacea, illustrating that around 40% to 60% of participants experienced moderate to good improvements [2].
However, it is crucial to recognize that while zinc shows promise, its effects are often analyzed in conjunction with other treatments, which complicates our understanding of its isolated impact. For instance, findings from a study indicated that adding zinc to isotretinoin treatment did not significantly enhance acne clearance but did reduce side effects for patients [9]. Hence, while the incorporation of zinc into acne treatment regimens appears to hold potential, ongoing research is necessary to ascertain its efficacy as a standalone solution, as patients are encouraged to consider a comprehensive treatment approach that may include multiple therapies alongside zinc.
Users have reported varied improvements in their skin symptoms after incorporating zinc into their routines, particularly regarding acne management. Many have noted noticeable changes within a week, with some claiming that their acne significantly cleared up or new breakouts ceased shortly after starting the supplements. For instance, one reviewer mentioned that after a week of use, their persistent cheek rashes and acne improved remarkably Read Review. Another user praised the rapid transformation of their daughter's skin, stating visible enhancement in just a week Read Review. Additionally, over more extended periods of two to three months, several users experienced further improvements in skin clarity and texture, with reduced oiliness in specific areas, such as the T-zone Read Review and overall complexion Read Review.
However, it's important to note that individual results can vary widely; while many users reported positive outcomes, some experienced no significant change or even exacerbation of symptoms, indicating that zinc's efficacy can depend on individual skin types and conditions Read Review. Thus, while zinc has been beneficial for many, it may not be a one-size-fits-all solution for acne treatment.
Users generally reported positive experiences when combining zinc with other supplements for acne management. For instance, one reviewer noted significant skin improvements after combining zinc with selenium, stating that their skin became cleaner and less oily in the T-zone after two months of use Read Review. This suggests that certain combinations can enhance the effects of zinc in combating acne. Additionally, another user who took zinc at night after meals found it beneficial in controlling oily skin while also healing mucous membranes, indicating a holistic approach to skin health Read Review.
However, it's worth noting that individual results can vary widely, and not all combinations yielded positive results. Some users reported no significant improvement or even exacerbation of their symptoms while taking zinc. For example, one individual experienced worsened acne while using zinc, suggesting that higher doses or specific combinations might not suit everyone Read Review. Overall, while many users found success in combining zinc with other supplements, particularly selenium, it's essential to consider individual skin types and conditions when determining the most effective regimen.
According to recent research, high-dose dietary zinc has shown promise as a treatment for acne. Specifically, studies suggest that doses may need to be substantial to observe significant anti-inflammatory effects. One study conducted with an acne mouse model found that high-dose zinc treatment resulted in reduced inflammation, providing a potentially effective therapeutic avenue for managing acne vulgaris [1]. Although the exact optimal dose of zinc can vary, anecdotal evidence hints that achieving adequate zinc levels often requires higher amounts than typical dietary intake.
In support of these findings, another study pointed out that around 40% to 60% of patients suffering from acne rosacea saw a moderate to good response from a topical zinc sulfate solution at a concentration of 5% [2]. However, while the benefits of zinc are becoming clearer, much remains inconclusive regarding the best dosage and delivery method. Therefore, it is advisable for individuals considering zinc for acne treatment to consult healthcare professionals for tailored advice regarding the optimal dosage that suits their specific needs and health conditions.
9
Acne relief
297 people found this helpful
After struggling with rashes on my cheeks for a year, zinc transformed my skin. Within a week of use, new acne stopped appearing. Now I use it as needed during menstruation. The results have been remarkable!
9
Quick effects observed
3 people found this helpful
I bought this for my teenage daughter, and within a week, her acne began to clear up!
8
Fewer rashes
80 people found this helpful
I began taking zinc to combat skin rashes as my doctor advised. Over two months, my acne reduced and my skin became more elastic, with no side effects. I’m very pleased with the results!
10
Clearer complexion
166 people found this helpful
Zinc is vital for boosting immunity and improving skin health. After taking it for a month and a half, my acne cleared up, my hair stopped shedding, and I regained my sense of smell post-COVID. It has worked wonders for me!
9
Clearer skin
530 people found this helpful
Zinc is essential for improving immunity, especially in autumn and winter. I combined it with selenium and noticed significant skin improvements after two months. My skin became cleaner and less oily in the T-zone, and I no longer needed foundation to cover acne and blemishes. I had no side effects from this zinc, as long as I took it after meals. Highly recommend it for your skin and nails!
0
Increased acne
8 people found this helpful
My acne worsened while taking zinc for a month. I've heard zinc may increase male hormone levels, possibly causing more rashes on my face. My skin has softened, but it seems oilier than before, suggesting it may not be suitable for me.
8
Reduced inflammation
338 people found this helpful
Solgar's zinc is a staple for me. It doesn’t cause nausea or bloating, and I take it at night after meals. Zinc has helped heal mucous membranes and clears up acne, controlling oily skin. The tiny tablets are easy to take, and I've noticed the positive changes in my skin health!
8
Zinc treatment shows promise for acne
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent.
We explored how zinc treatment may help with inflammatory skin conditions like acne vulgaris, rosacea, and hidradenitis suppurativa. These conditions can appear quite similar, which makes diagnosing them a bit tricky. By examining gene expression data across these three disorders, we noticed that certain zinc-binding proteins were consistently elevated in all cases.
Our hypothesis centers around these proteins possibly sequestering zinc, which could promote inflammation due to local zinc deficiency. To investigate this further, we identified high-dose dietary zinc as a potential therapeutic option. This was tested and validated in an acne mouse model, showing promising results for its effectiveness in reducing the inflammation associated with acne.
Although the study specifically highlighted the isolated effect of zinc, it strongly suggests that incorporating high doses of dietary zinc might offer a new avenue for treatment. This could be an encouraging option for those struggling with acne, pointing to a novel approach grounded in scientific findings.
8
Zinc effective for acne treatment
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
We investigated how zinc treatment affects acne, particularly focusing on its potential benefits for those suffering from acne rosacea. The study observed that zinc sulfate solution at a concentration of 5% played a notable role in reducing the severity of acne rosacea symptoms.
Findings indicated that around 40% to 60% of patients experienced a moderate to good response after using zinc. This suggests that zinc could be helpful for individuals looking for alternatives or supplements in their acne treatment regimen.
However, it's important to acknowledge that while zinc showed positive results, the isolated effect of zinc alone cannot be fully determined. It might have worked in conjunction with other treatment factors, which complicates our understanding of its effectiveness.
Therefore, we emphasize the need for further studies to clarify exactly how zinc contributes to acne treatment outcomes and to evaluate its role alongside other therapies.
5
Zinc and isotretinoin treatment study
Oral Zinc as a Novel Adjuvant and Sparing Therapy for Systemic Isotretinoin in Acne Vulgaris: A Preliminary Comparative Study.
We explored the potential benefits of adding oral zinc to low-dose isotretinoin therapy for those dealing with acne vulgaris (AV). By comparing two groups of participants, one receiving zinc along with a lower dose of isotretinoin and another group on the standard dosage, we aimed to see if this combination could enhance treatment outcomes and reduce side effects.
After monitoring sixty AV patients, it was found that both groups showed similar reductions in acne lesions and grading scores, meaning the zinc didn’t provide an additional benefit in clearing up acne compared to the standard treatment alone. However, patients who took zinc experienced significantly fewer treatment-related side effects, with only 20% reporting issues versus 76.7% in the standard isotretinoin group.
In terms of patient satisfaction and relapse rates, there was no notable difference between the two groups. While we did observe improvements in both groups, the addition of zinc appeared to serve primarily as a means to lessen the adverse effects of isotretinoin rather than significantly enhancing treatment efficacy. Thus, while the findings are promising for a more tolerable treatment pathway, more research is necessary to fully understand zinc's impact when combined with isotretinoin at varying dosages.
References
Li L, Hajam I, McGee JS, Tang Z, Zhang Y, et al. Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent. Exp Dermatol. 2024;33:e15145. doi:10.1111/exd.15145
Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4
Akman TC, Yazici M, Atila A, Mertoglu C. Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects. Biol Trace Elem Res. 2024;202:4858. doi:10.1007/s12011-023-04053-9
Li L, Hajam I, McGee JS, Tang Z, Zhang Y, et al. Comparative Transcriptome Analysis of Acne vulgaris, Rosacea, and Hidradenitis Suppurativa Supports High Dose Dietary Zinc as a Therapeutic Agent. medRxiv. 2023. doi:10.1101/2023.11.28.23299152
Shields A, Ly S, Wafae B, Chang YF, Manjaly P, et al. Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review. JAMA Dermatol. 2023;159:1373. doi:10.1001/jamadermatol.2023.3949
Tan YY, Wong LS, Nyam KL, Wittayanarakul K, Zawawi NA, et al. Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using and Its Effect on Acne Vulgaris. Molecules. 2023;28. doi:10.3390/molecules28196749
Xiang Y, Lu J, Mao C, Zhu Y, Wang C, et al. Ultrasound-triggered interfacial engineering-based microneedle for bacterial infection acne treatment. Sci Adv. 2023;9:eadf0854. doi:10.1126/sciadv.adf0854
Towersey L, Correia P, Fajgenbaum Feiges M, Euzébio Gonçalves Junior J, Sant'Anna B, et al. Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study. Clin Cosmet Investig Dermatol. 2023;16:119. doi:10.2147/CCID.S394123
Salah E. Oral Zinc as a Novel Adjuvant and Sparing Therapy for Systemic Isotretinoin in Acne Vulgaris: A Preliminary Comparative Study. J Clin Aesthet Dermatol. 2022;15:58.
Naji HH, Al-Azawi RSA, Ibrahim NJ, Kzar HH. Investigation of the Role of Zn/Cu Index and its Correlation with Physiological Activity of SOD 1 and GRx in Males with Acne Vulgaris. Arch Razi Inst. 2022;77:623. doi:10.22092/ARI.2021.356857.1928
Searle T, Ali FR, Al-Niaimi F. Zinc in dermatology. J Dermatolog Treat. 2022;33:2455. doi:10.1080/09546634.2022.2062282
Poizeau F, Plantier F, Bell H, Moyal-Barracco M. Vulvar Fordyce adenitis: A cohort of 45 women. Ann Dermatol Venereol. 2021;148:221. doi:10.1016/j.annder.2021.04.001
Tolino E, Skroza N, Mambrin A, Proietti I, Bernardini N, et al. An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris. J Clin Aesthet Dermatol. 2021;14:56.
Maillard A, Pastor D, Merat R. Anti-PD-1-Induced Hidradenitis Suppurativa. Dermatopathology (Basel). 2021;8:37. doi:10.3390/dermatopathology8010007
Abendrot M, Płuciennik E, Felczak A, Zawadzka K, Piątczak E, et al. Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations. Int J Mol Sci. 2021;22. doi:10.3390/ijms22041641
Yee BE, Richards P, Sui JY, Marsch AF. Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis. Dermatol Ther. 2020;33:e14252. doi:10.1111/dth.14252