Effectiveness of eight-week zinc supplementation on vitamin D status and leptin levels in a population of postmenopausal women: a double-blind randomized trial.
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Read More
9
Zinc gel improves menopausal symptoms
Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study.
We evaluated the impact of a zinc-containing vaginal moisturizer gel on postmenopausal women experiencing genitourinary symptoms of menopause (GSM). Some women hesitate to use hormonal treatments like vaginal estrogen, which can be highly effective. To explore an alternative, we asked 37 participants to apply the gel daily for two weeks while tracking their symptoms.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Read More
8
Zinc enhances antioxidant protection
Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial.
We assessed how zinc (Zn) supplementation can impact the health of postmenopausal women, particularly regarding their antioxidant status. In this study, fifty-one women participating were split into two groups: one receiving a placebo treatment and the other receiving zinc supplements. This double-blind randomized trial lasted for eight weeks and focused on measuring changes in mineral status along with different antioxidant markers in the blood.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Read More
Most Useful Reviews
9
Supports women's health
Zinc picolinate is vital for skin, hair, and nail health and plays a significant role for women, especially regarding menopause. Maintaining adequate zinc levels is crucial for fertility and a smooth menstrual cycle. On average, the daily zinc intake should be 10-20 mg, with a maximum of 30 mg.
Read More
4
Boosted immunity after covid
I ordered this zinc after recovering from COVID, as it's crucial for many bodily functions. A deficiency can lead to severe health issues, including reduced immunity and problems related to menopause. Signs of deficiency include frequent colds, dull hair, and impaired taste and smell.
Read More
7.5
Mucous membranes improved
2 people found this helpful
I wanted to strengthen my mucous membranes, so I tried drinking lemon water in the morning. Initially, it aggravated my esophagus. I bought these zinc supplements thinking my mucous membranes were weak. I take 1 tablet every few days due to my small body size. After a month, I resumed lemon water, and now it no longer irritates my esophagus. I can't be sure if the zinc alone helped, but I feel my mucous membranes have improved, possibly due to menopause symptoms.
Effectiveness of eight-week zinc supplementation on vitamin D status and leptin levels in a population of postmenopausal women: a double-blind randomized trial.
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Read More
9
Zinc gel improves menopausal symptoms
Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study.
We evaluated the impact of a zinc-containing vaginal moisturizer gel on postmenopausal women experiencing genitourinary symptoms of menopause (GSM). Some women hesitate to use hormonal treatments like vaginal estrogen, which can be highly effective. To explore an alternative, we asked 37 participants to apply the gel daily for two weeks while tracking their symptoms.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Read More
8
Zinc enhances antioxidant protection
Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial.
We assessed how zinc (Zn) supplementation can impact the health of postmenopausal women, particularly regarding their antioxidant status. In this study, fifty-one women participating were split into two groups: one receiving a placebo treatment and the other receiving zinc supplements. This double-blind randomized trial lasted for eight weeks and focused on measuring changes in mineral status along with different antioxidant markers in the blood.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Read More
8
Zinc improves nutritional markers post-menopause
Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B, and folate in a postmenopausal population.
In our study, we examined how zinc supplementation could affect menopausal women, particularly focusing on markers like homocysteine, vitamin B, and folate levels. We worked with 51 postmenopausal women aged between 44 and 76 years, dividing them into two groups: one received a placebo, while the other was given 50 mg of zinc daily for eight weeks.
After analyzing the results, we found that those who took zinc showed significantly higher folate levels compared to their baseline measurements. Additionally, we observed a noteworthy decrease in homocysteine levels when comparing the two groups after the intervention. Interestingly, we also noted a strong correlation between higher folate and vitamin B levels with lower homocysteine levels in the zinc group.
These findings suggest that zinc supplementation can have positive effects on certain nutritional markers in menopausal women. However, we emphasize the need for further research with larger sample sizes and refined dosing to validate and expand upon our results.
Read More
7
Zinc impacts postmenopausal obesity
Excess dietary zinc drives a Cushing's-like syndrome in ovariectomized mice - Implications for postmenopausal obesity.
We investigated the effects of dietary zinc on obesity related to menopause, particularly in female mice that underwent ovariectomy (Ovx). Our findings revealed that excess zinc led to significant weight gain and symptoms resembling Cushing's syndrome, even though these mice did not consume more food.
The accumulation of zinc in the adrenal glands played a crucial role by interfering with steroid production. This is particularly important since, in Ovx mice, adrenal steroids are the only source of estrogen. The lack of estrogen triggered adrenal hyperplasia and an increase in glucocorticoids, which contributed to the development of Cushing's-like symptoms.
Interestingly, our results showed that supplementing with adrenal steroids could counteract the negative impacts of excess zinc. We also found a positive correlation between plasma zinc levels and cortisol while noting a negative correlation with adrenal steroids and estrogen levels in overweight postmenopausal women.
These insights suggest that it may be beneficial for postmenopausal women to avoid high dietary zinc and consider adrenal steroid supplementation to help manage obesity effectively.
Zinc picolinate is vital for skin, hair, and nail health and plays a significant role for women, especially regarding menopause. Maintaining adequate zinc levels is crucial for fertility and a smooth menstrual cycle. On average, the daily zinc intake should be 10-20 mg, with a maximum of 30 mg.
Read More
4
Boosted immunity after covid
I ordered this zinc after recovering from COVID, as it's crucial for many bodily functions. A deficiency can lead to severe health issues, including reduced immunity and problems related to menopause. Signs of deficiency include frequent colds, dull hair, and impaired taste and smell.
Read More
7.5
Mucous membranes improved
2 people found this helpful
I wanted to strengthen my mucous membranes, so I tried drinking lemon water in the morning. Initially, it aggravated my esophagus. I bought these zinc supplements thinking my mucous membranes were weak. I take 1 tablet every few days due to my small body size. After a month, I resumed lemon water, and now it no longer irritates my esophagus. I can't be sure if the zinc alone helped, but I feel my mucous membranes have improved, possibly due to menopause symptoms.
Read More
7.5
Alleviated menopause symptoms
1 people found this helpful
Zinc picolinate is a fantastic form of zinc with a great dosage of 22mg. It's beneficial for stress and hormonal issues like acne and menopause, as it boosts testosterone while lowering DHT. I use it to manage breakouts during stressful times.
Read More
7.5
Restored hair elasticity
I purchased zinc picolinate after seeing it recommended on YouTube. The 22mg dosage suits Japanese women. I believe it's helping my hair regain elasticity lost due to menopause, making it a valuable addition to my routine.
Read More
Frequently Asked Questions
Menopause is a natural biological process that marks the end of a woman's reproductive years, characterized by the cessation of menstruation and a decline in hormonal levels, particularly estrogen and progesterone. Typically occurring between the ages of 45 and 55, menopause can bring a variety of physical and emotional changes. Common symptoms may include hot flashes, night sweats, mood swings, and changes in sleep patterns. It is important to note that menopause is a gradual process and often begins with perimenopause, where women may experience irregular periods and increased symptoms for several years before periods stop completely.
While menopause is a natural phase of life, it can have significant impacts on a woman's health and well-being. This transition can increase the risk of certain health issues, such as osteoporosis and cardiovascular disease, due in part to lowered hormone levels. Therefore, it is advisable for women to consult with healthcare providers to discuss potential management strategies and lifestyle adjustments during this time. These may include hormone replacement therapy, dietary changes, regular physical activity, and alternative therapies, all aimed at alleviating symptoms and promoting overall health during and after menopause.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc may play a supportive role during menopause, as it is known for its importance in numerous bodily functions, including immune response and hormone regulation. Some studies suggest that adequate zinc levels might help alleviate certain menopausal symptoms, such as mood swings, sleep disturbances, and fatigue. Additionally, zinc contributes to bone health, which is particularly important during menopause, as the decline in estrogen levels can lead to increased bone density loss.
However, it's worth noting that while zinc can contribute to overall health, it should not be viewed as a primary treatment for menopause-related symptoms. Women experiencing significant discomfort or health changes during menopause should consult a healthcare provider for personalized advice and treatment options. Supplementation of zinc should be approached with caution, as excessive intake can lead to adverse health effects. In summary, while zinc may offer some benefits during menopause, more research is needed to fully understand its impact and effectiveness.
Based on user reviews, the timeline for seeing results from zinc supplements during menopause varies among individuals. Some users report noticeable benefits within a month of consistent use. For instance, one reviewer mentioned feeling an improvement in their mucous membranes after taking zinc for about a month, although they couldn't definitively attribute the change solely to the supplement Read Review. Another user observed that it was positively impacting their hair elasticity related to menopause symptoms after starting the supplement, suggesting a potential timeline of similar duration Read Review.
However, it’s essential to acknowledge that responses to supplements can differ significantly. Some individuals may experience changes more rapidly, while others may take longer to notice the effects. Factors such as individual body chemistry, the severity of symptoms, and overall health may play a role in how quickly results are observed. As a general guideline, many users indicate that consistent use of zinc over several weeks appears to yield positive outcomes for menopause-related symptoms.
Zinc supplementation is increasingly recognized for its potential benefits in supporting the health of postmenopausal women, based on several scientific studies. One research found that zinc supplementation improved antioxidant status, with participants showing significant increases in antioxidant capacity after eight weeks of supplementation [2]. This is particularly important for postmenopausal women, who may experience weakened antioxidant defenses due to hormonal changes. Furthermore, the same group showed improvement in folate levels and a decrease in homocysteine levels, suggesting that zinc may positively influence nutritional markers during menopause [3].
Additionally, there is evidence indicating that zinc can alleviate common menopausal symptoms. A study evaluating a zinc-containing vaginal moisturizer demonstrated significant improvements in vaginal health indices and reduced discomfort related to genitourinary symptoms of menopause [7]. This non-hormonal approach can be particularly appealing for those hesitant to use traditional hormonal treatments. Overall, while more extensive research is necessary to further validate these findings, current evidence supports the notion that zinc supplementation can be beneficial during menopause in various aspects, from managing nutritional deficiencies to improving symptomatic relief.
Users have reported a range of improvements in symptoms after using zinc supplements, particularly in relation to menopause. For instance, one user noted that their mucous membranes improved after a month of taking zinc, which they used to support their delicate system during menopause, even if they couldn't confirm the supplement was solely responsible for the enhancement Read Review. Another reviewer found that zinc was beneficial for managing stress-related hormonal issues, observing its effect on acne, which can sometimes be exacerbated by menopause Read Review.
Additionally, some users indicated that the supplement helped in restoring hair elasticity that may have been diminished due to menopausal changes, showcasing its potential benefits for hair health Read Review. While these experiences highlight positive outcomes, it is essential to note that results can vary based on individual factors such as body chemistry and the severity of symptoms. Users emphasized that maintaining adequate zinc levels is crucial for overall health, especially during menopause Read Review. Individual results can differ significantly, so a consistent approach to supplementation may be necessary to see similar effects.
Users report that combining zinc supplements with other dietary practices and supplements can enhance the management of menopause symptoms. For example, one reviewer highlighted that their mucous membranes improved after supplementing with zinc, although they noted they couldn’t definitively attribute this improvement solely to zinc, suggesting that a holistic approach may be beneficial Read Review. Additionally, another user mentioned that zinc helps manage stress and hormonal issues associated with menopause, which can impact skincare routines and overall wellbeing Read Review.
Furthermore, some users believe that zinc plays a significant role in supporting additional aspects like hair health during menopause. One reviewer indicated that zinc was instrumental in restoring their hair elasticity, which they felt had been compromised due to hormonal changes Read Review. These insights suggest that integrating zinc with attention to overall nutrition and perhaps other supportive supplements could provide a comprehensive strategy for addressing menopausal challenges.
The optimal dose of zinc for treating menopausal women appears to be around 50 mg daily. In a study involving 51 postmenopausal women, participants who received this dosage over eight weeks showed significant improvements in nutritional markers, including higher folate levels and lower homocysteine levels compared to those on a placebo [3]. Another study confirmed these findings, indicating that the same dosage not only bolstered vitamin D levels but also influenced leptin levels, which helps regulate energy balance [4].
However, it is crucial to note that excessive zinc intake may lead to adverse effects, such as obesity-related issues, particularly in postmenopausal women [1]. Therefore, while a daily intake of 50 mg is supported by research for enhancing health markers, it is advisable for individuals to consult healthcare providers before beginning any supplementation to ensure it aligns with their specific health needs.
7.5
Mucous membranes improved
2 people found this helpful
I wanted to strengthen my mucous membranes, so I tried drinking lemon water in the morning. Initially, it aggravated my esophagus. I bought these zinc supplements thinking my mucous membranes were weak. I take 1 tablet every few days due to my small body size. After a month, I resumed lemon water, and now it no longer irritates my esophagus. I can't be sure if the zinc alone helped, but I feel my mucous membranes have improved, possibly due to menopause symptoms.
7.5
Restored hair elasticity
I purchased zinc picolinate after seeing it recommended on YouTube. The 22mg dosage suits Japanese women. I believe it's helping my hair regain elasticity lost due to menopause, making it a valuable addition to my routine.
7.5
Alleviated menopause symptoms
1 people found this helpful
Zinc picolinate is a fantastic form of zinc with a great dosage of 22mg. It's beneficial for stress and hormonal issues like acne and menopause, as it boosts testosterone while lowering DHT. I use it to manage breakouts during stressful times.
9
Supports women's health
Zinc picolinate is vital for skin, hair, and nail health and plays a significant role for women, especially regarding menopause. Maintaining adequate zinc levels is crucial for fertility and a smooth menstrual cycle. On average, the daily zinc intake should be 10-20 mg, with a maximum of 30 mg.
8
Zinc enhances antioxidant protection
Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial.
We assessed how zinc (Zn) supplementation can impact the health of postmenopausal women, particularly regarding their antioxidant status. In this study, fifty-one women participating were split into two groups: one receiving a placebo treatment and the other receiving zinc supplements. This double-blind randomized trial lasted for eight weeks and focused on measuring changes in mineral status along with different antioxidant markers in the blood.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
8
Zinc improves nutritional markers post-menopause
Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B, and folate in a postmenopausal population.
In our study, we examined how zinc supplementation could affect menopausal women, particularly focusing on markers like homocysteine, vitamin B, and folate levels. We worked with 51 postmenopausal women aged between 44 and 76 years, dividing them into two groups: one received a placebo, while the other was given 50 mg of zinc daily for eight weeks.
After analyzing the results, we found that those who took zinc showed significantly higher folate levels compared to their baseline measurements. Additionally, we observed a noteworthy decrease in homocysteine levels when comparing the two groups after the intervention. Interestingly, we also noted a strong correlation between higher folate and vitamin B levels with lower homocysteine levels in the zinc group.
These findings suggest that zinc supplementation can have positive effects on certain nutritional markers in menopausal women. However, we emphasize the need for further research with larger sample sizes and refined dosing to validate and expand upon our results.
9
Zinc gel improves menopausal symptoms
Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study.
We evaluated the impact of a zinc-containing vaginal moisturizer gel on postmenopausal women experiencing genitourinary symptoms of menopause (GSM). Some women hesitate to use hormonal treatments like vaginal estrogen, which can be highly effective. To explore an alternative, we asked 37 participants to apply the gel daily for two weeks while tracking their symptoms.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
9
Zinc enhances vitamin D in menopause
Effectiveness of eight-week zinc supplementation on vitamin D status and leptin levels in a population of postmenopausal women: a double-blind randomized trial.
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
7
Zinc impacts postmenopausal obesity
Excess dietary zinc drives a Cushing's-like syndrome in ovariectomized mice - Implications for postmenopausal obesity.
We investigated the effects of dietary zinc on obesity related to menopause, particularly in female mice that underwent ovariectomy (Ovx). Our findings revealed that excess zinc led to significant weight gain and symptoms resembling Cushing's syndrome, even though these mice did not consume more food.
The accumulation of zinc in the adrenal glands played a crucial role by interfering with steroid production. This is particularly important since, in Ovx mice, adrenal steroids are the only source of estrogen. The lack of estrogen triggered adrenal hyperplasia and an increase in glucocorticoids, which contributed to the development of Cushing's-like symptoms.
Interestingly, our results showed that supplementing with adrenal steroids could counteract the negative impacts of excess zinc. We also found a positive correlation between plasma zinc levels and cortisol while noting a negative correlation with adrenal steroids and estrogen levels in overweight postmenopausal women.
These insights suggest that it may be beneficial for postmenopausal women to avoid high dietary zinc and consider adrenal steroid supplementation to help manage obesity effectively.
References
Zhao Y, Wang Y, Hu L, Chen H, Xiao X, et al. Excess dietary zinc drives a Cushing's-like syndrome in ovariectomized mice - Implications for postmenopausal obesity. Biochem Biophys Res Commun. 2022;630:101. doi:10.1016/j.bbrc.2022.09.042
Vázquez-Lorente H, Molina-López J, Herrera-Quintana L, Gamarra-Morales Y, Quintero-Osso B, et al. Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial. Exp Gerontol. 2022;162:111766. doi:10.1016/j.exger.2022.111766
Vázquez-Lorente H, Herrera-Quintana L, Molina-López J, Gamarra Y, Planells E. Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B, and folate in a postmenopausal population. J Trace Elem Med Biol. 2022;71:126942. doi:10.1016/j.jtemb.2022.126942
Vázquez-Lorente H, Molina-López J, Herrera-Quintana L, Gamarra-Morales Y, López-González B, et al. Effectiveness of eight-week zinc supplementation on vitamin D status and leptin levels in a population of postmenopausal women: a double-blind randomized trial. J Trace Elem Med Biol. 2021;65:126730. doi:10.1016/j.jtemb.2021.126730
Csikós A, Kozma B, Pór Á, Kovács I, Lampé R, et al. Zinc Transporter 9 (SLC30A9) Expression Is Decreased in the Vaginal Tissues of Menopausal Women. Biol Trace Elem Res. 2021;199:4011. doi:10.1007/s12011-020-02525-w
Damjanovich P, Sipos AG, Larson K, Cunningham TD, Takacs P, et al. Cervicovaginal lavage fluid zinc level as a marker of vaginal atrophy. Menopause. 2020;27:776. doi:10.1097/GME.0000000000001536
Takacs P, Kozma B, Erdodi B, Jakab A, Larson K, et al. Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study. J Menopausal Med. 2019;25:63. doi:10.6118/jmm.2019.25.1.63