Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 11 Reviews
8.1
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
3 g
1%*
Magnesium (as magnesium malate trihydrate)
425 mg
101%
Sodium
10 mg
<1%
Magnesium Malate Trihydrate
3.75 g
†
Malic Acid (as magnesium malate trihydrate and malic acid)
2.5 g
†
Top Medical Research Studies
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
We investigated whether supplementation with alkaline minerals could ease chronic low back pain. In a study with 82 participants, those who took a lactose-based alkaline multimineral supplement for four weeks reported a significant 49% reduction in pain scores.
We also noted an increase in blood buffering capacity and pH, indicating an improved acid-base balance. Although intracellular magnesium levels increased, plasma magnesium slightly decreased, suggesting that while the supplementation helped alleviate pain, it didn't significantly impact magnesium levels overall.
This study highlights the potential benefits of correcting acid-base balance to reduce low back pain symptoms.
We also noted an increase in blood buffering capacity and pH, indicating an improved acid-base balance. Although intracellular magnesium levels increased, plasma magnesium slightly decreased, suggesting that while the supplementation helped alleviate pain, it didn't significantly impact magnesium levels overall.
This study highlights the potential benefits of correcting acid-base balance to reduce low back pain symptoms.
Read More
9
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Read More
Most Useful Reviews
9
Knee pain mitigated.
136 people found this helpful
After battling Lyme disease, I faced knee pain and muscle stiffness. I turned to Magnesium Malate during a particularly difficult night and found relief quickly. Now, after three weeks, I’m experiencing a significant reduction in pain and an improvement in my energy levels. This supplement has had a miraculous effect on my overall wellbeing.
Read More
7.5
Fibromyalgia symptoms reduced.
32 people found this helpful
I've been taking Magnesium Malate regularly for years. It assists with muscle relaxation, alleviates migraines, and enhances my mood and sleep. If I stop taking it, I'm more prone to tension and muscle cramps, negatively affecting daily life. It notably helps with my fibromyalgia symptoms and keeps my digestion on track, making it an essential part of my routine.
Read More
9
Pain medication reduced.
7 people found this helpful
I'm genuinely surprised by the effects of this and the Fibro-Response supplement. As someone with fibromyalgia, I've dramatically reduced my reliance on pain medication. I've been able to sleep better and feel a noticeable improvement in my overall wellbeing. I never anticipated feeling good enough to forget to take pain relief!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
- All Researches
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Read More
9
We investigated whether supplementation with alkaline minerals could ease chronic low back pain. In a study with 82 participants, those who took a lactose-based alkaline multimineral supplement for four weeks reported a significant 49% reduction in pain scores.
We also noted an increase in blood buffering capacity and pH, indicating an improved acid-base balance. Although intracellular magnesium levels increased, plasma magnesium slightly decreased, suggesting that while the supplementation helped alleviate pain, it didn't significantly impact magnesium levels overall.
This study highlights the potential benefits of correcting acid-base balance to reduce low back pain symptoms.
We also noted an increase in blood buffering capacity and pH, indicating an improved acid-base balance. Although intracellular magnesium levels increased, plasma magnesium slightly decreased, suggesting that while the supplementation helped alleviate pain, it didn't significantly impact magnesium levels overall.
This study highlights the potential benefits of correcting acid-base balance to reduce low back pain symptoms.
Read More
8
We explored the potential of magnesium-containing microspheres to help manage intervertebral disc degeneration (IVDD), a condition often linked with back pain. This innovative treatment focuses on using microspheres that respond to reactive oxygen species, which are indicators of oxidative stress often seen in IVDD. By targeting these harmful agents, we aimed to reduce the associated inflammation and pain.
The microspheres, composed of a polymer shell and a magnesium core, work by releasing hydrogen gas in response to oxidative conditions, which can help neutralize damaging free radicals in the body. We observed significant improvements in a rat model of disc degeneration, which included less damage to the disc structure, reduced cell death, and overall better disc health.
The results of this study highlight magnesium's role as a key component in enhancing the antioxidative capacity of the treatment. This not only mitigates the effects of IVDD but also supports the idea that antioxidant therapies may hold promise for alleviating back pain. Importantly, we noted that this approach showed strong biocompatibility and minimal toxicity, making it a potential option for future clinical applications.
The microspheres, composed of a polymer shell and a magnesium core, work by releasing hydrogen gas in response to oxidative conditions, which can help neutralize damaging free radicals in the body. We observed significant improvements in a rat model of disc degeneration, which included less damage to the disc structure, reduced cell death, and overall better disc health.
The results of this study highlight magnesium's role as a key component in enhancing the antioxidative capacity of the treatment. This not only mitigates the effects of IVDD but also supports the idea that antioxidant therapies may hold promise for alleviating back pain. Importantly, we noted that this approach showed strong biocompatibility and minimal toxicity, making it a potential option for future clinical applications.
Read More
8
We conducted a study to explore how magnesium treatment and mountain hiking might alleviate non-specific chronic low back pain (nscLBP). In this randomized controlled trial, we divided eighty participants into three groups: one engaged in green exercise (mountain hiking), another combined hiking with magnesium-calcium-sulfate thermal baths, and a control group received no treatment.
Our findings showed significant improvements in back pain among participants who participated in hiking and bathing in thermal water compared to those who didn't receive any intervention. However, it is important to note that we cannot isolate the benefits of magnesium treatment since it was combined with the physical activity of hiking. Therefore, while magnesium's involvement is notable, its individual impact remains unclear from our results.
This study highlights the promise of integrating physical activities like mountain hiking alongside therapeutic treatments for managing chronic back pain. Future research should delve deeper into the long-term effects of such multi-faceted therapies to fully understand the role of magnesium in this context.
Our findings showed significant improvements in back pain among participants who participated in hiking and bathing in thermal water compared to those who didn't receive any intervention. However, it is important to note that we cannot isolate the benefits of magnesium treatment since it was combined with the physical activity of hiking. Therefore, while magnesium's involvement is notable, its individual impact remains unclear from our results.
This study highlights the promise of integrating physical activities like mountain hiking alongside therapeutic treatments for managing chronic back pain. Future research should delve deeper into the long-term effects of such multi-faceted therapies to fully understand the role of magnesium in this context.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Knee pain mitigated.
136 people found this helpful
After battling Lyme disease, I faced knee pain and muscle stiffness. I turned to Magnesium Malate during a particularly difficult night and found relief quickly. Now, after three weeks, I’m experiencing a significant reduction in pain and an improvement in my energy levels. This supplement has had a miraculous effect on my overall wellbeing.
Read More
7.5
Fibromyalgia symptoms reduced.
32 people found this helpful
I've been taking Magnesium Malate regularly for years. It assists with muscle relaxation, alleviates migraines, and enhances my mood and sleep. If I stop taking it, I'm more prone to tension and muscle cramps, negatively affecting daily life. It notably helps with my fibromyalgia symptoms and keeps my digestion on track, making it an essential part of my routine.
Read More
9
Pain medication reduced.
7 people found this helpful
I'm genuinely surprised by the effects of this and the Fibro-Response supplement. As someone with fibromyalgia, I've dramatically reduced my reliance on pain medication. I've been able to sleep better and feel a noticeable improvement in my overall wellbeing. I never anticipated feeling good enough to forget to take pain relief!
Read More
9
Chronic pain eliminated.
3 people found this helpful
These have remarkably helped with my constipation and chronic pain. After years of discomfort in my legs and hips, I’ve been pain-free for months following just a week of taking these. I realised my low back pain stemmed partly from constipation, and it's now resolved. I take 4-6 daily with meals, pleased with such an effective and inexpensive supplement.
Read More
8.5
Effective anxiety relief
2 people found this helpful
They work well but contain too many fillers. If you seek relief from physical pain related to stress and anxiety, these supplements can be beneficial. I advise against taking them at night as they can provide an energy boost. I am very pleased with the relief from back pain and anxiety these supplements provided. However, I won’t repurchase due to the fillers and preservatives. If that doesn’t bother you, these may be helpful for bodily aches and pains.
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Frequently Asked Questions
7
Soothed back pain
3 people found this helpful
I use this magnesium when I struggle to sleep or experience back pain. It effectively relaxes my muscles and soothes discomfort.
5
Magnesium shows no significant benefit
We looked into how magnesium sulfate affects chronic low back pain by comparing it with triamcinolone in patients receiving caudal blocks. Our study involved 40 participants who were randomly assigned to receive a local anesthetic combined with either magnesium sulfate or triamcinolone.
Over the course of the study, we tracked changes in pain levels and functional ability using standard pain scales. While we found that both medications contributed to improvements in pain levels and quality of life, there was no significant difference between magnesium and triamcinolone overall.
However, we noted that patients receiving magnesium sulfate reported a statistically lower pain score at three months compared to those receiving triamcinolone. Unfortunately, this was the only notable difference we observed. Overall, both treatments seemed to provide lasting benefits for up to three months, suggesting they could be effective options in managing low back pain.
Over the course of the study, we tracked changes in pain levels and functional ability using standard pain scales. While we found that both medications contributed to improvements in pain levels and quality of life, there was no significant difference between magnesium and triamcinolone overall.
However, we noted that patients receiving magnesium sulfate reported a statistically lower pain score at three months compared to those receiving triamcinolone. Unfortunately, this was the only notable difference we observed. Overall, both treatments seemed to provide lasting benefits for up to three months, suggesting they could be effective options in managing low back pain.
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
9
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
4
We looked into how magnesium might help with back pain, particularly in the context of combining it with other treatments. It’s clear that magnesium has been evaluated for its potential benefits in reducing discomfort linked to back pain. However, the evidence we reviewed often involved magnesium as part of a broader mix rather than as a standalone treatment.
While some studies indicated positive responses, isolating magnesium's specific impact proved challenging, making it difficult to draw firm conclusions about its effectiveness by itself. We did observe that magnesium treatment was often considered in conjunction with other therapies, suggesting that it might enhance the overall pain management strategy rather than act as a miracle solution on its own.
Ultimately, while magnesium is an interesting component in addressing back pain, further research focusing exclusively on its effects is necessary to fully understand how well it works in this context.
While some studies indicated positive responses, isolating magnesium's specific impact proved challenging, making it difficult to draw firm conclusions about its effectiveness by itself. We did observe that magnesium treatment was often considered in conjunction with other therapies, suggesting that it might enhance the overall pain management strategy rather than act as a miracle solution on its own.
Ultimately, while magnesium is an interesting component in addressing back pain, further research focusing exclusively on its effects is necessary to fully understand how well it works in this context.
References
- Dadkhah P, Hashemi M, Taheri M, Alizadeh Ojoor A, Jaffari M, et al. A Comparison of Analgesic Efficacy of Triamcinolone vs Magnesium Sulfate as Adjuvants in Caudal Block in Patients with Low Back Pain: A Double-Blind Randomized Controlled Trial. Anesth Pain Med. 2024;14:e145718. doi:10.5812/aapm-145718
- Zhang T, Wang Y, Li R, Xin J, Zheng Z, et al. ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration. Acta Biomater. 2023;158:475. doi:10.1016/j.actbio.2023.01.020
- Celenlioglu AE, Sir E, Ors-Yildirim N, Yildirim AK, Ince ME, et al. Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting. J Vasc Surg Venous Lymphat Disord. 2023;11:517. doi:10.1016/j.jvsv.2022.09.008
- Marchesi N, Govoni S, Allegri M. Non-drug pain relievers active on non-opioid pain mechanisms. Pain Pract. 2022;22:255. doi:10.1111/papr.13073
- Huber D, Grafetstätter C, Proßegger J, Pichler C, Wöll E, et al. Green exercise and mg-ca-SO thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial. BMC Musculoskelet Disord. 2019;20:221. doi:10.1186/s12891-019-2582-4
- Yousef AA, Al-deeb AE. A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component. Anaesthesia. 2013;68:260. doi:10.1111/anae.12107
- Vormann J, Worlitschek M, Goedecke T, Silver B. Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain. J Trace Elem Med Biol. 2001;15:179.
