Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc methionine sulfate complex [OptiZinc®])
30 mg
273%
Copper (as copper citrate)
300 mcg
33%
Top Medical Research Studies
8
The study focused on understanding how dietary copper affects physiological issues tied to reduced levels of peptidylglycine alpha-amidating monooxygenase (PAM), especially regarding hypothyroidism.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
Read More
7
Zinc's uncertain role in hypothyroidism
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
Read More
Most Useful Reviews
10
Resolved my symptoms
96 people found this helpful
After being diagnosed with subclinical hypothyroidism five years ago, I switched from levothyroxine to natural supplements like zinc. Within two months, my depression, fatigue, and other symptoms significantly improved. I've maintained this approach for five years, averaging only one cold a year. Zinc has boosted my immunity, enabling me to enjoy a healthier, more active life.
Read More
7.5
Supports immune health
This great mix is something I take almost constantly as part of my treatment for hypothyroidism, and during winter to support my immune system. The product is outstanding, and the ingredients certainly work well; I recommend it to everyone.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
The study focused on understanding how dietary copper affects physiological issues tied to reduced levels of peptidylglycine alpha-amidating monooxygenase (PAM), especially regarding hypothyroidism.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
Read More
7
Zinc's uncertain role in hypothyroidism
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Resolved my symptoms
96 people found this helpful
After being diagnosed with subclinical hypothyroidism five years ago, I switched from levothyroxine to natural supplements like zinc. Within two months, my depression, fatigue, and other symptoms significantly improved. I've maintained this approach for five years, averaging only one cold a year. Zinc has boosted my immunity, enabling me to enjoy a healthier, more active life.
Read More
7.5
Supports immune health
This great mix is something I take almost constantly as part of my treatment for hypothyroidism, and during winter to support my immune system. The product is outstanding, and the ingredients certainly work well; I recommend it to everyone.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Nikkhah M, Vafa M, Abiri B, Golgiri F, Sarbakhsh P, et al. The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial. Med J Islam Repub Iran. 2024;38:133. 10.47176/mjiri.38.133
- Bousquet-Moore D, Ma XM, Nillni EA, Czyzyk TA, Pintar JE, et al. Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper. Endocrinology. 2009;150:1739. 10.1210/en.2008-1202
