ω3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α.
We uncovered intriguing insights into how eicosapentaenoic acid (EPA) and its metabolite, 12-hydroxyeicosapentaenoic acid (12-HEPE), play a role in managing allergic responses, particularly in the skin. Our study revealed that when mice consumed an omega-3 fatty acid-rich diet, 12-HEPE became a significant metabolite in their skin.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
Read More
9
Eicosapentaenoic acid benefits allergies
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
We explored the impact of dietary eicosapentaenoic acid (EPA) in children suffering from atopic dermatitis, a common allergic skin condition. In a well-structured study, forty-eight children were divided into two groups: one received 250 mg of EPA twice daily, while the other was given a placebo for four weeks.
The study aimed to measure the effectiveness of EPA by examining improvements in the SCORing Atopic Dermatitis (SCORAD) index and the need for topical corticosteroids. What we found was quite promising—after just two weeks, the EPA group showed significant improvement in their SCORAD scores compared to the placebo group.
Additionally, by the end of four weeks, fewer children in the EPA group required corticosteroids, indicating a potential reduction in the severity of their condition. Overall, the results suggest that EPA supplementation is both effective and well-tolerated among young patients with atopic dermatitis, offering a supportive strategy for managing this allergy-related issue.
Read More
9
Eicosapentaenoic acid reduces inflammation
Effect of Omega-3 Polyunsaturated Fatty Acids Intake on Eosinophil Airway Inflammation in University Athletes.
We assessed how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences airway inflammation related to allergies in university athletes. In our study, we had 23 male participants divided into three groups based on their levels of airway inflammation, measured by fractional exhaled nitric oxide (FeNO).
These athletes took daily supplements containing 600 mg of EPA for three weeks. During this time, we tracked changes in their FeNO levels and other respiratory factors. Our findings revealed a significant drop in FeNO levels among athletes with eosinophilic airway inflammation, indicating a reduction in airway inflammation.
Notably, while the athletes with high FeNO levels benefited from the supplementation, those without eosinophilic characteristics saw no significant changes in their respiratory status. This suggests that EPA may be particularly effective for certain allergy-related conditions, rather than universally beneficial for all types of respiratory issues.
Read More
Most Useful Reviews
9
Resolved allergies
10 people found this helpful
I bought this on my doctor's recommendation. After taking it for three months, my body returned to normal and I had no allergies. I gave it three stars to keep the price down, but the brand is excellent!
Read More
2
No relief from allergies
6 people found this helpful
Did not meet my expectations. I purchased this for its anti-inflammatory properties due to my eczema and allergies. Other fish oils have alleviated my symptoms, even at lower omega-3 dosages, but this one had no effect despite a higher content.
Read More
9
Significantly reduced allergies
2 people found this helpful
I've noticed a significant reduction in my allergic reactions after taking this product for three months. My hay fever and pet allergies have decreased, allowing me to stop taking medication after ten years. Fish oil seems to work well for me.
Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase alleviate ovalbumin‑induced allergic asthma in mice by reducing airway inflammation and oxidative stress.
We explored the potential of lipid mediators derived from docosahexaenoic acid (DHA) for alleviating allergic asthma. Using a model where mice were challenged with ovalbumin (OVA) to induce asthma-like symptoms, we administered lipid mediators that included 17S-monohydroxy DHA, resolvin D5, and protectin DX. These treatments led to significant improvements in key aspects of asthma such as reduced inflammatory cell infiltration and lower levels of Th2 cytokines.
Following treatment with the lipid mediators, we observed decreased levels of interleukin-6, tumor necrosis factor-α, and IgE—important markers associated with allergic reactions. There was a notable reduction in inflammation and oxidative stress in lung tissues, which suggests a protective effect on the lungs. Additionally, histological examinations revealed fewer signs of inflammation and mucus secretion.
The results indicate that DHA-derived lipid mediators may effectively mitigate the symptoms of allergic asthma and offer a promising new approach for treatment. They seem to act by reducing inflammation and improving antioxidant defenses within the lungs.
Read More
9.5
New hypoallergenic formula shows promise
Hypoallergenicity assessment of an extensively hydrolyzed whey-protein formula in cow's milk allergic infants.
We set out to assess a new extensively hydrolyzed whey-protein formula, which includes docosahexaenoic acid (DHA), for infants with cow's milk allergy (CMA). This study involved 34 children, primarily with IgE-mediated reactions, participating in a double-blind, placebo-controlled food challenge. Remarkably, all the children tolerated the new formula during the trial. This is significant since the American Academy of Pediatrics states that successful tolerance in over 90% of CMA children is crucial for a product to be considered hypoallergenic.
Although our focus was on the overall efficacy and safety of this formula, it's important to note that while DHA was included, we stopped short of isolating its specific impact on allergy outcomes. Thus, while we noted that this new formula is well-tolerated and associated with healthy growth and gastrointestinal tolerability, we cannot definitively state the effect of DHA alone on allergies. We recognize that further research would be needed to explore DHA's specific role in allergy management.
Read More
9
Eicosapentaenoic acid benefits allergies
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
We explored the impact of dietary eicosapentaenoic acid (EPA) in children suffering from atopic dermatitis, a common allergic skin condition. In a well-structured study, forty-eight children were divided into two groups: one received 250 mg of EPA twice daily, while the other was given a placebo for four weeks.
The study aimed to measure the effectiveness of EPA by examining improvements in the SCORing Atopic Dermatitis (SCORAD) index and the need for topical corticosteroids. What we found was quite promising—after just two weeks, the EPA group showed significant improvement in their SCORAD scores compared to the placebo group.
Additionally, by the end of four weeks, fewer children in the EPA group required corticosteroids, indicating a potential reduction in the severity of their condition. Overall, the results suggest that EPA supplementation is both effective and well-tolerated among young patients with atopic dermatitis, offering a supportive strategy for managing this allergy-related issue.
Read More
9
Eicosapentaenoic acid reduces inflammation
Effect of Omega-3 Polyunsaturated Fatty Acids Intake on Eosinophil Airway Inflammation in University Athletes.
We assessed how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences airway inflammation related to allergies in university athletes. In our study, we had 23 male participants divided into three groups based on their levels of airway inflammation, measured by fractional exhaled nitric oxide (FeNO).
These athletes took daily supplements containing 600 mg of EPA for three weeks. During this time, we tracked changes in their FeNO levels and other respiratory factors. Our findings revealed a significant drop in FeNO levels among athletes with eosinophilic airway inflammation, indicating a reduction in airway inflammation.
Notably, while the athletes with high FeNO levels benefited from the supplementation, those without eosinophilic characteristics saw no significant changes in their respiratory status. This suggests that EPA may be particularly effective for certain allergy-related conditions, rather than universally beneficial for all types of respiratory issues.
Read More
9
Eicosapentaenoic acid and allergies
Long-Chain Polyunsaturated Fatty Acid Status at Birth and Development of Childhood Allergy: A Systematic Review.
We focused on understanding how the levels of eicosapentaenoic acid (EPA) at birth relate to allergies in children. Through a systematic review, we analyzed multiple studies, narrowing it down to 14 key articles that matched our criteria. The findings suggested that lower levels of EPA in cord blood were linked to a higher likelihood of allergic conditions later in childhood.
When we looked deeper, we discovered that not only high levels of EPA, but also docosahexaenoic acid (DHA) and total n-3 long-chain polyunsaturated fatty acids were associated with a significant drop—at least 38%—in the risk of developing allergies in various studies. Additionally, we noted that the higher the levels of EPA, DHA, and docosapentaenoic acid in cord blood, the lower the laboratory measurements indicating allergic traits.
This paints a promising picture for the potential of these fatty acids in managing allergy risks. Overall, our findings can guide recommendations for the fatty acid intake that pregnant women should consider for better health outcomes for their children.
I bought this on my doctor's recommendation. After taking it for three months, my body returned to normal and I had no allergies. I gave it three stars to keep the price down, but the brand is excellent!
Read More
2
No relief from allergies
6 people found this helpful
Did not meet my expectations. I purchased this for its anti-inflammatory properties due to my eczema and allergies. Other fish oils have alleviated my symptoms, even at lower omega-3 dosages, but this one had no effect despite a higher content.
Read More
9
Significantly reduced allergies
2 people found this helpful
I've noticed a significant reduction in my allergic reactions after taking this product for three months. My hay fever and pet allergies have decreased, allowing me to stop taking medication after ten years. Fish oil seems to work well for me.
Read More
9
No fish taste
This is a good quality fish oil that doesn't have any fishy taste and it hasn’t caused any allergies or stomach upset for me.
Read More
9
Seafood allergy concern
I take this product due to my allergy to most seafood.
Allergies are the body's immune system responses to substances known as allergens, which can be harmless in most individuals. When a person with allergies encounters these allergens, their immune system mistakenly identifies them as a threat and launches a response. This can lead to symptoms ranging from mild, such as sneezing, itching, and rashes, to severe reactions known as anaphylaxis, which can be life-threatening. Common allergens include pollen, pet dander, certain foods like nuts and shellfish, insect stings, and medications.
Managing allergies often involves avoiding known allergens and using medications such as antihistamines or corticosteroids to alleviate symptoms. In some cases, doctors might recommend allergy shots or immunotherapy to help patients build tolerance over time. If you suspect you have allergies, consulting with a healthcare professional for proper diagnosis and treatment options is crucial. Understanding your triggers and how to live with allergies can significantly improve your quality of life.
Sports Fish Oil Omegas are specialized dietary supplements derived from the fatty tissues of fish, specifically designed to provide a rich source of omega-3 fatty acids. These omega-3s, primarily EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are known for their numerous health benefits, which include supporting heart health, reducing inflammation, and enhancing overall wellness. Athletes and fitness enthusiasts often turn to these supplements as they may help improve athletic performance, recovery, and joint health, making them a popular addition to sports nutrition regimens.
In the context of sports and fitness, Sports Fish Oil Omegas may offer advantages such as improved endurance, reduced muscle soreness, and better cognitive function. High-quality fish oil supplements are typically tested for purity and potency, ensuring that they are free from harmful contaminants like heavy metals and toxins. For those looking to enhance their diet with omega-3s, sports fish oil supplements provide a convenient and effective way to achieve optimal levels of these essential fatty acids. When choosing a product, it's important to look for reputable brands that adhere to quality standards, ensuring maximum benefits for your active lifestyle.
Based on user reviews, the time it takes to see results from this supplement for allergies can vary, but many users report noticeable improvements after several weeks of consistent use. For instance, one user mentioned experiencing a significant reduction in allergic reactions after three months of taking the product, allowing them to stop their allergy medications after ten years of reliance on them Read Review. Another review echoed this timeline, with a user stating that after three months of use, their allergies returned to normal Read Review.
However, not everyone experiences the same results or timeline; some users reported immediate benefits within just a few days, indicating that while three months may be the medium-term expectation for many, quicker results are also possible Read Review. Ultimately, individual experiences may vary, and users may need to assess their personal reactions and adjustments over time.
Based on the available scientific research, the efficacy of eicosapentaenoic acid (EPA) as a supplement for managing allergies appears to be nuanced and complex. While some studies suggest that EPA may have potential benefits, particularly in conditions like atopic dermatitis and certain allergic inflammatory responses, there are limitations regarding its standalone effectiveness. For instance, research shows promising improvements in children's atopic dermatitis when supplemented with EPA, indicating a potential reduction in inflammation and a decreased need for corticosteroids [3]. However, when EPA was used in isolation or in conjunction with other treatments, such as fish oil and probiotics, the results have been less clear, often failing to show significant reductions in allergy prevalence [2].
Additionally, other studies highlight the importance of EPA in immune modulation but fail to provide strong evidence for its benefits against all allergic conditions. For example, while EPA may help reduce airway inflammation in specific populations, like athletes with eosinophilic airway issues, it did not yield significant changes in those without this characteristic [4]. Overall, while the research acknowledges EPA's potential role in influencing allergic responses and supports further investigation, it also emphasizes that results can vary significantly based on individual conditions and other concurrent treatments.
Based on user reviews, many individuals have reported noticeable improvements in their allergy symptoms after using this fish oil supplement. For example, one user mentioned a significant reduction in their allergic reactions, particularly hay fever and pet allergies, after three months of consistent use, allowing them to stop taking medication for the first time in a decade Read Review. Another user, who struggled with allergies related to temperature changes, found that increasing their omega-3 intake through this supplement improved their overall situation Read Review.
However, it's important to note that individual results can vary significantly. Some reviewers cited no improvement or even adverse reactions, indicating that while many users experienced benefits, others did not find the product effective or had allergic reactions to it Read ReviewRead Review. A few users reported positive outcomes shortly after starting the supplement, suggesting that responses can vary in terms of timing and effectiveness Read Review. Ultimately, potential users should consider these diverse experiences and may need to assess their own reactions over time.
Users have shared a variety of experiences regarding the use of this fish oil supplement in conjunction with other allergy treatments. Several reviewers reported significant improvements in their allergy symptoms, leading them to reduce or stop their reliance on traditional allergy medications entirely. For instance, one user noted a significant reduction in hay fever and pet allergies after taking the product consistently for three months, mentioning that this allowed them to discontinue medication for the first time in a decade Read Review. Another user also reported an enhancement in their situation after increasing their omega-3 intake through this supplement, which proved beneficial in managing temperature-related allergies Read Review.
Despite these positive outcomes, there were also notable instances where users experienced adverse reactions or no effect at all. Some individuals stated that the supplement did not meet their expectations for relieving allergy symptoms, with one user mentioning they had better results with other fish oils Read Review. Additionally, a few users cited allergic reactions or itchiness after taking the supplement, suggesting that, while it may be effective for some, it may not be suitable for everyone Read ReviewRead Review. These varied experiences underline the importance of considering personal health conditions and preferences when integrating this supplement into a broader allergy management plan.
Based on user reviews, experiences with the right dose of Sports Fish Oil Omegas for treating allergies vary significantly. Some users, like one reviewer who reported using the product for three months, noted a significant reduction in allergic reactions such as hay fever and pet allergies, allowing them to discontinue their medication after a decade of reliance on it Read Review. Another user echoed the positive effects for their allergies, describing the fish oil's benefits for managing temperature-related allergies Read Review. However, not all users found success; one individual found it ineffective despite its higher omega-3 content compared to other fish oils that had previously helped with their eczema and allergies Read Review.
In terms of dosage, there were no specific recommendations provided in the reviews that indicated an optimal amount for alleviating allergy symptoms. Some individuals reported no allergic reactions when switching to this brand after using it for different durations, such as three days Read Review; however, several others also experienced allergic reactions, suggesting that personal tolerance may vary widely Read ReviewRead Review. Overall, while some users praised the efficacy of the fish oil for allergies, determining the right dose appears to be a subjective experience.
9
Significantly reduced allergies
2 people found this helpful
I've noticed a significant reduction in my allergic reactions after taking this product for three months. My hay fever and pet allergies have decreased, allowing me to stop taking medication after ten years. Fish oil seems to work well for me.
9
Resolved allergies
10 people found this helpful
I bought this on my doctor's recommendation. After taking it for three months, my body returned to normal and I had no allergies. I gave it three stars to keep the price down, but the brand is excellent!
6
No allergic reactions
1 people found this helpful
I've used it for three days without any allergic reactions, which makes me happy. I was initially concerned about switching brands, but this one has been excellent so far.
7.5
Reduced nighttime coughing
4 people found this helpful
After turning 50, I've developed an allergy to temperature differences, experiencing coughing at night and in response to wind. To manage my lipids better, I've increased my omega-3 intake, which has improved my situation.
2
No relief from allergies
6 people found this helpful
Did not meet my expectations. I purchased this for its anti-inflammatory properties due to my eczema and allergies. Other fish oils have alleviated my symptoms, even at lower omega-3 dosages, but this one had no effect despite a higher content.
0
Allergic reaction
I experienced allergic reactions after taking fish oil due to my allergies.
0
First allergic reaction
The product seems fine, but I had an allergic reaction for the first time among nutritional supplements. If I take this alone, various parts of my body itch. I am open to trying other omega-3 options.
9
Eicosapentaenoic acid benefits allergies
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
We explored the impact of dietary eicosapentaenoic acid (EPA) in children suffering from atopic dermatitis, a common allergic skin condition. In a well-structured study, forty-eight children were divided into two groups: one received 250 mg of EPA twice daily, while the other was given a placebo for four weeks.
The study aimed to measure the effectiveness of EPA by examining improvements in the SCORing Atopic Dermatitis (SCORAD) index and the need for topical corticosteroids. What we found was quite promising—after just two weeks, the EPA group showed significant improvement in their SCORAD scores compared to the placebo group.
Additionally, by the end of four weeks, fewer children in the EPA group required corticosteroids, indicating a potential reduction in the severity of their condition. Overall, the results suggest that EPA supplementation is both effective and well-tolerated among young patients with atopic dermatitis, offering a supportive strategy for managing this allergy-related issue.
4
Fish oil's unclear allergy impact
Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old.
We explored the effects of eicosapentaenoic acid, a key component of fish oil, on allergic diseases in infants. In a double-blind trial involving 439 pregnant women, participants were divided into four groups: those receiving fish oil, those receiving probiotics, those receiving both, and a control group getting placebos. Supplements were taken from early pregnancy until six months after birth.
Our findings indicated that, overall, the use of fish oil and/or probiotics did not significantly lower the risk of childhood allergic diseases or atopy. The only notable outcome was linked to the probiotic group, which showed a decreased risk of recurrent wheezing by the time the children were two years old. Unfortunately, we could not isolate the specific impact of eicosapentaenoic acid alone on allergy prevention since it was combined with probiotics.
This suggests that while eicosapentaenoic acid is promising, its benefits for allergies remain unclear and need to be further investigated in future research.
9
Eicosapentaenoic acid reduces inflammation
Effect of Omega-3 Polyunsaturated Fatty Acids Intake on Eosinophil Airway Inflammation in University Athletes.
We assessed how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences airway inflammation related to allergies in university athletes. In our study, we had 23 male participants divided into three groups based on their levels of airway inflammation, measured by fractional exhaled nitric oxide (FeNO).
These athletes took daily supplements containing 600 mg of EPA for three weeks. During this time, we tracked changes in their FeNO levels and other respiratory factors. Our findings revealed a significant drop in FeNO levels among athletes with eosinophilic airway inflammation, indicating a reduction in airway inflammation.
Notably, while the athletes with high FeNO levels benefited from the supplementation, those without eosinophilic characteristics saw no significant changes in their respiratory status. This suggests that EPA may be particularly effective for certain allergy-related conditions, rather than universally beneficial for all types of respiratory issues.
References
Li SY, Zheng PY, Zhai YY, Zhang YD, Gan H, et al. [Analysis of the effect of early subcutaneous specific immunotherapy on the levels of dust mite allergen-specific antibodies and polyunsaturated fatty acid metabolism]. Zhonghua Yu Fang Yi Xue Za Zhi. 2024;58:778. doi:10.3760/cma.j.cn112150-20240124-00083
Komulainen M, Saros L, Vahlberg T, Nermes M, Jartti T, et al. Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old. Pediatr Allergy Immunol. 2023;34:e14004. doi:10.1111/pai.14004
Mirrahimi B, Moazemi M, Eslami N, Jamshidi E, Mir M, et al. Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial. J Pediatr Pharmacol Ther. 2023;28:29. doi:10.5863/1551-6776-28.1.29
Imai T, Takada Y, Watanabe K. Effect of Omega-3 Polyunsaturated Fatty Acids Intake on Eosinophil Airway Inflammation in University Athletes. J Clin Med Res. 2022;14:466. doi:10.14740/jocmr4825
Decsi T, Marosvölgyi T, Muszil E, Bódy B, Szabó É. Long-Chain Polyunsaturated Fatty Acid Status at Birth and Development of Childhood Allergy: A Systematic Review. Life (Basel). 2022;12. doi:10.3390/life12040526
Saika A, Nagatake T, Hirata SI, Sawane K, Adachi J, et al. ω3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α. FASEB J. 2021;35:e21354. doi:10.1096/fj.202001687R
Kanda N, Hoashi T, Saeki H. Nutrition and Atopic Dermatitis. J Nippon Med Sch. 2021;88:171. doi:10.1272/jnms.JNMS.2021_88-317
Miles EA, Childs CE, Calder PC. Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) and the Developing Immune System: A Narrative Review. Nutrients. 2021;13. doi:10.3390/nu13010247
Barman M, Rabe H, Hesselmar B, Johansen S, Sandberg AS, et al. Cord Blood Levels of EPA, a Marker of Fish Intake, Correlate with Infants' T- and B-Lymphocyte Phenotypes and Risk for Allergic Disease. Nutrients. 2020;12. doi:10.3390/nu12103000
Hoppenbrouwers T, Fogliano V, Garssen J, Pellegrini N, Willemsen LEM, et al. Specific Polyunsaturated Fatty Acids Can Modulate Human moDC2s and Subsequent Th2 Cytokine Release. Front Immunol. 2020;11:748. doi:10.3389/fimmu.2020.00748
Saika A, Nagatake T, Kishino S, Park SB, Honda T, et al. 17(),18()-epoxyeicosatetraenoic acid generated by cytochrome P450 BM-3 from inhibits the development of contact hypersensitivity via G-protein-coupled receptor 40-mediated neutrophil suppression. FASEB Bioadv. 2020;2:59. doi:10.1096/fba.2019-00061
Su Y, Choi HS, Kwon SK, Han Y, Cho SC, et al. Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase alleviate ovalbumin‑induced allergic asthma in mice by reducing airway inflammation and oxidative stress. Mol Med Rep. 2025;31. doi:10.3892/mmr.2025.13451
Sato A, Sato G, Yabuki A, Ogawa Y, Nemoto H, et al. Ameliorative effects of squid phospholipids from Todarodes pacificus on atopic dermatitis-like lesions in NC/Nga mice. Arch Dermatol Res. 2025;317:239. doi:10.1007/s00403-024-03773-9
Wang R, Patel D, Goruk S, Richard C, Field CJ. Feeding Docosahexaenoic Acid and Arachidonic Acid during Suckling and Weaning Contributes to Oral Tolerance Development by Beneficially Modulating the Intestinal Cytokine and Immunoglobulin Levels in an Allergy-Prone Brown Norway Rat Model. J Nutr. 2024;154:3790. doi:10.1016/j.tjnut.2024.10.021
Lee C, Dartt DA. Sex-dependent differential increase of specialized pro-resolving mediators in extracellular vesicles secreted by human primary conjunctival goblet cells during allergic inflammation. Life Sci. 2024;357:123058. doi:10.1016/j.lfs.2024.123058
Huang XW, Pang SW, Yang LZ, Han T, Chen JM, et al. TNFSF14 mediates the impact of docosahexaenoic acid on atopic dermatitis: a Mendelian randomization study. Eur Rev Med Pharmacol Sci. 2024;28:107. doi:10.26355/eurrev_202401_34896
Peh HY, Brüggemann TR, Duvall MG, Nshimiyimana R, Nijmeh J, et al. Resolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation. Allergy. 2024;79:739. doi:10.1111/all.15920
Patel D, Munhoz J, Goruk S, Tsai S, Richard C, et al. Correction: Maternal diet supplementation with high-docosahexaenoic-acid canola oil, along with arachidonic acid, promotes immune system development in allergy-prone BALB/c mouse ofspring at 3 weeks of age. Eur J Nutr. 2024;63:341. doi:10.1007/s00394-023-03264-z
Patel D, Munhoz J, Goruk S, Richard C, Field CJ. The Programming Effect of Plant-Based DHA, Along with Equivalent AA, on Immune System and Oral Tolerance Development in Six-Week Allergy Prone BALB/c Pups. J Nutr. 2023;153:2482. doi:10.1016/j.tjnut.2023.06.002
Figueroa-Garduño I, Escamilla-Núñez C, Barraza-Villarreal A, Hernández-Cadena L, Onofre-Pardo EN, et al. Docosahexaenoic Acid Effect on Prenatal Exposure to Arsenic and Atopic Dermatitis in Mexican Preschoolers. Biol Trace Elem Res. 2023;201:3152. doi:10.1007/s12011-022-03411-3
Dahdah L, Roelofs M, Knipping K, de Vries E, Rijnierse A, et al. Hypoallergenicity assessment of an extensively hydrolyzed whey-protein formula in cow's milk allergic infants. Pediatr Allergy Immunol. 2022;33:e13814. doi:10.1111/pai.13814
Patel D, Goruk S, Richard C, Field CJ. Combined Supplementation with Arachidonic and Docosahexaenoic Acids in T Helper Type-2 Skewed Brown Norway Rat Offspring is Beneficial in the Induction of Oral Tolerance toward Ovalbumin and Immune System Development. J Nutr. 2022;152:2165. doi:10.1093/jn/nxac118