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SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 MicroLingual® Tablet
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
9
Vitamin D improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
Directly assesses vitamin D's effects
We conducted a thorough exploration of how vitamin D supplementation can affect hypothyroidism, particularly in patients with Hashimoto's thyroiditis (HT). Our findings draw from a meta-analysis of twelve randomized controlled trials, involving a total of 862 participants. These studies compared the effects of vitamin D against placebo or no treatment, focusing on various thyroid function indicators and autoantibodies.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
Read More
9
Vitamin D aids hypothyroid complications
Potential therapeutic impacts of vitamin D on hypothyroid-induced heart and kidney fibrosis and oxidative status in male rat.
Highly relevant to hypothyroid treatment
We investigated how vitamin D supplementation affects hypothyroidism, focusing on its impact on heart and kidney health. In our study, we used forty male Wistar rats, dividing them into four groups: control, hypothyroid, and hypothyroid treated with two doses of vitamin D. After six weeks, we examined various biochemical markers and evaluated fibrosis in the heart and kidneys.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Read More
8
Vitamin D's impact on hypothyroidism
Relationship between vitamin D and adolescents' hypothyroidism - a cross-sectional study.
Study shows correlation, not treatment
We aimed to understand how vitamin D, specifically measured as 25(OH)D, correlates with hypothyroidism in adolescents. Our study involved 180 participants from West Kazakhstan, and we carefully analyzed their blood samples for key indicators, including thyroid-stimulating hormone (TSH) and free thyroxine (T4).
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
Read More
Most Useful Reviews
8.8
Improved wellbeing
My doctor prescribed treatment for hypothyroidism, and I've started to feel much better. The dosage is quite low, which is convenient. I place it under my tongue, and it dissolves quickly – much better than the half an hour of porridge we usually experience.
Read More
8
Supports health
Excellent vitamin D! My nutritionist recommended this form for my hypothyroidism. The dosage is preventative, and I feel safe ordering it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
9
Vitamin D aids hypothyroid complications
Potential therapeutic impacts of vitamin D on hypothyroid-induced heart and kidney fibrosis and oxidative status in male rat.
Highly relevant to hypothyroid treatment
We investigated how vitamin D supplementation affects hypothyroidism, focusing on its impact on heart and kidney health. In our study, we used forty male Wistar rats, dividing them into four groups: control, hypothyroid, and hypothyroid treated with two doses of vitamin D. After six weeks, we examined various biochemical markers and evaluated fibrosis in the heart and kidneys.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Read More
9
Vitamin D improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
Directly assesses vitamin D's effects
We conducted a thorough exploration of how vitamin D supplementation can affect hypothyroidism, particularly in patients with Hashimoto's thyroiditis (HT). Our findings draw from a meta-analysis of twelve randomized controlled trials, involving a total of 862 participants. These studies compared the effects of vitamin D against placebo or no treatment, focusing on various thyroid function indicators and autoantibodies.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
Read More
9
Vitamin D aids Hashimoto's outcomes
Therapeutic effect of vitamin D in Hashimoto's thyroiditis: a prospective, randomized and controlled clinical trial in China.
Study effectively explores supplementation impact
We aimed to investigate the effects of Vitamin D supplements on women recently diagnosed with Hashimoto's Thyroiditis (HT), a condition that can lead to hypothyroidism. This study was carefully structured as a randomized clinical trial that included a control group for comparison, allowing us to draw clearer conclusions about the effectiveness of Vitamin D.
Over six months, we observed that women receiving Vitamin D experienced significant health benefits. Specifically, those treated saw a notable decrease in Thyroid Peroxidase Antibody (TPOAb) levels, which is a marker of thyroid inflammation. Additionally, markers of thyroid function, such as Free Triiodothyronine (FT3) and Free Thyroxine (FT4), increased, while Thyroid-Stimulating Hormone (TSH) levels decreased. This combination of changes suggests that Vitamin D can help slow the progression of hypothyroidism and enhance thyroid function.
Overall, these findings indicate that Vitamin D supplementation can be a useful adjunct in managing Hashimoto's Thyroiditis, potentially leading to improved health outcomes for patients with this condition.
Over six months, we observed that women receiving Vitamin D experienced significant health benefits. Specifically, those treated saw a notable decrease in Thyroid Peroxidase Antibody (TPOAb) levels, which is a marker of thyroid inflammation. Additionally, markers of thyroid function, such as Free Triiodothyronine (FT3) and Free Thyroxine (FT4), increased, while Thyroid-Stimulating Hormone (TSH) levels decreased. This combination of changes suggests that Vitamin D can help slow the progression of hypothyroidism and enhance thyroid function.
Overall, these findings indicate that Vitamin D supplementation can be a useful adjunct in managing Hashimoto's Thyroiditis, potentially leading to improved health outcomes for patients with this condition.
Read More
8
Vitamin D's impact on hypothyroidism
Relationship between vitamin D and adolescents' hypothyroidism - a cross-sectional study.
Study shows correlation, not treatment
We aimed to understand how vitamin D, specifically measured as 25(OH)D, correlates with hypothyroidism in adolescents. Our study involved 180 participants from West Kazakhstan, and we carefully analyzed their blood samples for key indicators, including thyroid-stimulating hormone (TSH) and free thyroxine (T4).
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
Read More
7
Vitamin D and hypothyroidism explored
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
Moderate relevance to vitamin D
We conducted a thoughtful exploration into how vitamin D and other micronutrients might influence hypothyroidism, particularly looking at thyroid function, metabolism, and quality of life. In this double-blind, randomized controlled trial, we involved 104 patients who were already receiving levothyroxine for their hypothyroidism. They were split into two groups; one received a combination of micronutrients, including vitamin D, while the other group received a placebo.
After eight weeks, we observed some impacts on insulin resistance and quality of life among those receiving the micronutrient supplement, suggesting that these nutrients could play a role in improving overall well-being in hypothyroid patients. However, while vitamin D is part of the treatment, we found it challenging to isolate its direct effect due to its combination with other nutrients.
Ultimately, while our findings indicate potential benefits, they also emphasize the need for further clinical trials to confirm these results and better understand the role of vitamin D in managing hypothyroidism.
After eight weeks, we observed some impacts on insulin resistance and quality of life among those receiving the micronutrient supplement, suggesting that these nutrients could play a role in improving overall well-being in hypothyroid patients. However, while vitamin D is part of the treatment, we found it challenging to isolate its direct effect due to its combination with other nutrients.
Ultimately, while our findings indicate potential benefits, they also emphasize the need for further clinical trials to confirm these results and better understand the role of vitamin D in managing hypothyroidism.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
8.8
Improved wellbeing
My doctor prescribed treatment for hypothyroidism, and I've started to feel much better. The dosage is quite low, which is convenient. I place it under my tongue, and it dissolves quickly – much better than the half an hour of porridge we usually experience.
8
Supports health
Excellent vitamin D! My nutritionist recommended this form for my hypothyroidism. The dosage is preventative, and I feel safe ordering it.
