NOW Supplements NOW Supplements Methyl B-12 5000 mcg

Correlation Between Nitrous Oxide and Functional Vitamin B12 Deficiency Resulting in Subacute Combined Degeneration of the Spinal Cord: A Case Report.

Most Relevant Research

We examined a remarkable case involving the effects of nitrous oxide (NO) on vitamin B12 levels and its neurological consequences. Nitrous oxide is not just a useful tool in medical and food industries; it is sometimes misused by young adults for recreational purposes. This misuse can lead to functional vitamin B12 deficiency, which in turn may result in serious neurological issues like peripheral neuropathy and subacute combined degeneration (SACD) of the spinal cord.

In this specific case, we identified a functional B12 deficiency, characterized by borderline normal serum vitamin B12 levels, but with increased levels of methylmalonic acid and homocysteine—key indicators of vitamin deficiency. Remarkably, after administering intramuscular vitamin B12, we observed significant clinical improvement in the patient’s condition. This suggests that vitamin B12 treatment can be effective in reversing the neurological damage caused by nitrous oxide-induced deficiency.

Our findings highlight the importance of recognizing the neurological risks associated with nitrous oxide misuse and the potential for vitamin B12 treatment to alleviate serious symptoms in affected individuals.

Quick recovery

Most Useful Review

The product was as described. It cured my cat's diabetic neuropathy in just a few days!

Anemia

SCIENTIFIC SCORE

Moderately Effective

Based on 11 Researches

Vitamin B12 effectively treats anemia

An Unusual Case of Hemolytic Anemia: A Case Report.

Most Relevant Research

We observed a compelling case surrounding the impact of vitamin B12 on anemia, particularly in a 62-year-old man facing severe deficiencies due to factors like drug use, hepatitis C, smoking, and alcoholism. Initially, this patient presented with symptoms such as fatigue, fever, and confusion, raising concerns about more critical conditions like thrombotic thrombocytopenic purpura (TTP). Laboratory tests indicated severe pancytopenia and signs of hemolysis, making the situation quite alarming.

However, further investigation revealed that the root cause was a significant deficiency of vitamin B12 coupled with folate. This discovery shifted our focus toward treatment strategies that addressed the underlying deficiency rather than applying unnecessary and invasive procedures like plasmapheresis. Upon administering vitamin B12 injections, we witnessed a refreshing turnaround as the patient's blood counts began to normalize progressively, along with an alleviation of symptoms.

This case emphasizes the necessity for healthcare providers to consider vitamin B12 deficiency when diagnosing patients presenting with hemolytic anemia and thrombocytopenia. By doing so, unnecessary treatments can be avoided, paving the way for a swift recovery through proper vitamin supplementation.

9.5

Effective vitamin remedy

Most Useful Review

Delicious and effective! My husband had peeling at the corners of his lips, a sign of vitamin B12 deficiency. Many years ago, he suffered from anemia due to B12 deficiency, starting with similar peeling. This time, he took vitamins immediately, and everything improved, restoring his health. I recommend it for anyone in need! If I was helpful, do let me know.

Back Pain

SCIENTIFIC SCORE

Moderately Effective

Based on 16 Researches

Vitamin B12 aids low back pain

Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.

Most Relevant Research

We conducted a thorough investigation to understand whether intramuscular vitamin B12 treatment could effectively relieve low back pain. This study was designed as a double-blind, placebo-controlled trial involving 60 patients aged 18 to 65 who suffered from mechanical low back pain or sciatic neuritis. Each participant had a history of back pain lasting from six months to five years and reported significant pain intensity according to a standard scale.

By comparing two groups—the one receiving vitamin B12 injections and the other receiving a placebo—we focused on measuring changes in pain and disability levels, as well as any changes in paracetamol consumption. What we found was quite impressive. Both groups reported decreases in pain and disability. However, those who received vitamin B12 showed significantly better results compared to the placebo group. The difference was not only notable in terms of pain relief but also in lower dependency on paracetamol for pain management.

Our findings confirm that vitamin B12 can be a safe and effective option for patients with low back pain, particularly for those who don't have any signs of nutritional deficiency. The data suggest that patients experiencing this common ailment could consider discussing vitamin B12 treatment with their healthcare provider as part of their pain management strategy.

9.5

Shoulder pain relief

Most Useful Review

Eliminated my frozen shoulder pain. I suffered from frozen shoulder for years. After months of massage, I regained 75% of my motion, but the pain remained. I began taking one of these daily and within three days, my pain was nearly gone. I now take them every third day and remain virtually pain-free in my shoulders.

Diabetes

SCIENTIFIC SCORE

Possibly Effective

Based on 4 Researches

Vitamin B12 improves eye movements

The Effectiveness of Steroid Versus Vitamin Therapy in the Improvement of Extraocular Movements in Patients With Diabetic Cranial Nerve Palsy: A Comparative Study.

Most Relevant Research

We explored the effectiveness of vitamin B12 in treating diabetic ocular nerve palsy, a complication that can occur in people with diabetes. In a recent study, fifty individuals with this condition were divided into two groups. One group received steroid treatments while the other was treated with vitamin B12 injections.

After assessing ocular movements at three points during treatment, we observed a notable improvement in those receiving vitamin B12 compared to those receiving steroids. Specifically, the vitamin B12 group showed an enhancement of eye movements by an average of 1.04, while the steroid group had a lesser improvement of 0.75. This difference was statistically significant, suggesting that vitamin B12 may be more effective in aiding recovery of eye movement in these patients.

Importantly, treating diabetic neuropathy with vitamin supplementation not only addresses possible nutritional deficiencies but could also improve overall quality of life for patients. This study highlights the potential benefits of vitamin B12 therapy, making it an appealing option for individuals dealing with the effects of diabetic-related nerve issues.

8.8

Nerve regeneration success

Most Useful Review

This triple B vitamin combo has been instrumental in regenerating nerves damaged by diabetes. I'm no longer on pain medication, and I've even regained some sensation in my feet. This family's business prioritises quality, which I appreciate.

Frozen Shoulder

I had severe pain from frozen shoulder for a few years. After months of trigger point massage and using my back buddy cane, I regained about 75% of my range of motion, but the pain lingered. After starting this supplement daily, my pain nearly disappeared within three days. Now I take it every third day and I am virtually pain-free in my shoulders. The results have been amazing, and I attribute this solely to the supplements.