' 
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 8 Reviews
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
1,360 mcg DFE** (800 mcg folic acid)
340%
Vitamin B-12 (as Cyanocobalamin)
25 mcg
1042%
Top Medical Research Studies
8
Long-term PPI effects analyzed
Gastric atrophy and intestinal metaplasia in a patient on long-term proton pump inhibitor therapy.
Combination therapy complicates results
We explored the case of a 74-year-old man who had been taking proton pump inhibitors for 20 years to manage symptoms of gastroesophageal reflux disease. Despite stopping his acid-reducing medications for a month, he showed an unusually high gastric pH level, indicating a significant decrease in stomach acidity. This condition may have led to gastric atrophy and intestinal metaplasia, as revealed through multiple biopsies of his stomach lining. Interestingly, after halting all anti-secretory drugs and starting only prokinetic treatment, the patient reported a significant improvement in heartburn symptoms.
During follow-up, although he developed symptoms of peripheral neuropathy—which were found to be related to a low level of vitamin B12—prompt treatment with vitamin B12 injections alleviated this issue. However, the correlation between improved heartburn symptoms and the vitamin B12 therapy is difficult to establish because the patient was also on prokinetics, which could have contributed to his symptom relief. Overall, our findings indicate that while vitamin B12 treatment offered benefits in this case, isolating its specific effect on heartburn remains challenging due to the combination therapy involved.
During follow-up, although he developed symptoms of peripheral neuropathy—which were found to be related to a low level of vitamin B12—prompt treatment with vitamin B12 injections alleviated this issue. However, the correlation between improved heartburn symptoms and the vitamin B12 therapy is difficult to establish because the patient was also on prokinetics, which could have contributed to his symptom relief. Overall, our findings indicate that while vitamin B12 treatment offered benefits in this case, isolating its specific effect on heartburn remains challenging due to the combination therapy involved.
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Most Useful Reviews
9.5
No heartburn noted
Folic acid was prescribed by my gynaecologist, and I took 1 piece with my spouse three months prior to our planned pregnancy. During the first trimester, I continued taking it as it comes in a convenient size, has no flavour, and does not cause heartburn. From the second trimester onwards, I switched to a vitamin complex for pregnant women. I was pleased with the results.
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9.5
No discomfort experienced
I now trust the manufacturer entirely. I do not experience heartburn or stomach discomfort from their products. I've just started taking folic acid and believe it will have a targeted effect.
Read More
9.5
Essential during pregnancy
This folic acid is good as it does not cause heartburn, making it indispensable during pregnancy.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Long-term PPI effects analyzed
Gastric atrophy and intestinal metaplasia in a patient on long-term proton pump inhibitor therapy.
Combination therapy complicates results
We explored the case of a 74-year-old man who had been taking proton pump inhibitors for 20 years to manage symptoms of gastroesophageal reflux disease. Despite stopping his acid-reducing medications for a month, he showed an unusually high gastric pH level, indicating a significant decrease in stomach acidity. This condition may have led to gastric atrophy and intestinal metaplasia, as revealed through multiple biopsies of his stomach lining. Interestingly, after halting all anti-secretory drugs and starting only prokinetic treatment, the patient reported a significant improvement in heartburn symptoms.
During follow-up, although he developed symptoms of peripheral neuropathy—which were found to be related to a low level of vitamin B12—prompt treatment with vitamin B12 injections alleviated this issue. However, the correlation between improved heartburn symptoms and the vitamin B12 therapy is difficult to establish because the patient was also on prokinetics, which could have contributed to his symptom relief. Overall, our findings indicate that while vitamin B12 treatment offered benefits in this case, isolating its specific effect on heartburn remains challenging due to the combination therapy involved.
During follow-up, although he developed symptoms of peripheral neuropathy—which were found to be related to a low level of vitamin B12—prompt treatment with vitamin B12 injections alleviated this issue. However, the correlation between improved heartburn symptoms and the vitamin B12 therapy is difficult to establish because the patient was also on prokinetics, which could have contributed to his symptom relief. Overall, our findings indicate that while vitamin B12 treatment offered benefits in this case, isolating its specific effect on heartburn remains challenging due to the combination therapy involved.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
No heartburn noted
Folic acid was prescribed by my gynaecologist, and I took 1 piece with my spouse three months prior to our planned pregnancy. During the first trimester, I continued taking it as it comes in a convenient size, has no flavour, and does not cause heartburn. From the second trimester onwards, I switched to a vitamin complex for pregnant women. I was pleased with the results.
Read More
9.5
No discomfort experienced
I now trust the manufacturer entirely. I do not experience heartburn or stomach discomfort from their products. I've just started taking folic acid and believe it will have a targeted effect.
9.5
Essential during pregnancy
This folic acid is good as it does not cause heartburn, making it indispensable during pregnancy.
9.5
Well absorbed product
I experienced no heartburn with this product. It is well absorbed and beneficial for women’s health.
9.5
Convenient and effective
During my pregnancy, I found the small pill convenient and it did not cause heartburn, in contrast to the pharmacy options.
