We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
Read More
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
Read More
9
Zinc compounds as acne treatment
Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations.
We examined the potential of zinc compounds, particularly zinc-amino acid complexes, to effectively treat acne. This study focused on how these zinc formulations could not only help with acne but also ensure safety for the skin.
Initially, we checked the cytotoxicity of the zinc complexes on human skin cells, demonstrating their safety. We then evaluated their antibacterial properties, which are crucial for combating acne-causing bacteria. After finding promising results, we selected zinc complexes with glycine and histidine to create unique gel formulations.
The next steps involved thorough testing of these gel preparations for stability, purity, and tolerability. We confirmed that they maintained their quality over time, showed no irritation or allergic reactions in a patch test with 25 volunteers, and exhibited high microbiological purity.
Ultimately, our findings suggest that these zinc-based gels can be a valuable topical option for acne treatment due to their strong antibacterial performance and minimal toxicity to skin cells. Our dermatological formulations appear safe and effective, contributing positively to acne management.
Read More
Most Useful Reviews
9
Clear skin achieved
1415 people found this helpful
Zinc has transformed my skin! It aids in renewing skin cells and collagen formation, reducing acne and dryness while helping to heal wounds. I've noticed fewer pimples and stronger hair after a month of use. Unlike other zinc supplements, this one doesn't make me feel unwell. I wholeheartedly recommend it!
Read More
7.5
Skin disease prevention
493 people found this helpful
This tiny zinc capsule has immense benefits. It plays a vital role in skin cell renewal and collagen formation, helping to combat acne and dryness. Considering its essentiality for health and beauty, I realised maintaining adequate zinc is crucial.
Read More
9
Improved skin health
208 people found this helpful
I purchased zinc to support my immune system during cold season, but I've found it has numerous other benefits for my skin. With zinc, my acne has significantly reduced, and my nails and hair are stronger. I'm very pleased with the results.
We investigated the effectiveness of a novel microneedle patch designed for acne treatment, which incorporates zinc-based nanoparticles. This patch combines sodium hyaluronate with zinc porphyrin-based metal-organic frameworks and zinc oxide. By using ultrasound to release activated oxygen, we observed a remarkable antibacterial efficiency, achieving a 99.73% reduction in acne-causing bacteria within just 15 minutes.
Zinc plays a crucial role in this innovative approach. Not only does it help eliminate harmful bacteria, but it also appears to enhance skin health. The presence of zinc ions promotes the up-regulation of genes associated with DNA replication, which supports the growth of fibroblasts. This is a vital process for skin repair and rejuvenation, showing that zinc can potentially contribute to both the treatment and recovery of acne-affected skin.
Overall, our findings suggest that this microneedle patch, which utilizes zinc and ultrasound-responsive technology, represents a promising strategy for effectively managing acne without relying on traditional antibiotics.
We investigated how zinc treatment affects acne, particularly focusing on its potential benefits for those suffering from acne rosacea. The study observed that zinc sulfate solution at a concentration of 5% played a notable role in reducing the severity of acne rosacea symptoms.
Findings indicated that around 40% to 60% of patients experienced a moderate to good response after using zinc. This suggests that zinc could be helpful for individuals looking for alternatives or supplements in their acne treatment regimen.
However, it's important to acknowledge that while zinc showed positive results, the isolated effect of zinc alone cannot be fully determined. It might have worked in conjunction with other treatment factors, which complicates our understanding of its effectiveness.
Therefore, we emphasize the need for further studies to clarify exactly how zinc contributes to acne treatment outcomes and to evaluate its role alongside other therapies.
Read More
9
Zinc oxide nanoparticles combat acne
Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using and Its Effect on Acne Vulgaris.
We assessed the potential of zinc oxide nanoparticles in combating acne. Using biogenically synthesized zinc oxide, we mixed it with a polymer to create a topical nanogel aimed at treating acne. Through rigorous testing against acne-causing bacteria, we observed that these biogenic nanoparticles showed a promising antibacterial effect, particularly against Gram-positive bacteria.
Notably, the particle size of our biogenic zinc oxide nanoparticles measured around 20 nm, indicating a high degree of purity. When pitted against chemogenic counterparts, the biogenic version proved to be more effective. This suggests that zinc oxide, especially when produced biogenically, could be a valuable addition to skincare products targeting acne.
Moreover, the study highlights the environment-friendly aspect of using biogenic zinc oxide in skincare formulations, making it a preferable choice for those concerned about sustainability. Our findings suggest that these hybrid nanogels could serve as an effective solution against skin infections associated with acne, adding to their appeal in modern skincare.
Read More
9
Zinc gel shows promise for acne
Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study.
We wanted to find out how effective a cleansing gel containing salicylic acid, zinc gluconate, and lipohydroxy acids is for treating truncal acne. Conducted over 84 days, our study included 51 individuals with mild to moderate acne, and we tracked various skin conditions like the number of acne lesions and the overall skin barrier health.
After regular use of the gel, we observed a significant reduction in total acne lesions—over half were improved by the end of the study. While non-inflammatory lesions saw a drop of 64% and inflammatory lesions were reduced by nearly 30%, the key point is that zinc gluconate was part of a trio of ingredients, making it challenging to pinpoint its specific contribution.
When we considered skin barrier function, a notable improvement was also measured—21.26% better at Day 84. Patients reported no significant side effects or intolerances, suggesting that the ingredients within the gel, including zinc, were well tolerated.
Overall, the evidence hints at zinc's potential benefits as part of a combination treatment against acne. But since it was used together with other active ingredients, we can't solely credit zinc for the results observed.
Read More
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
Zinc has transformed my skin! It aids in renewing skin cells and collagen formation, reducing acne and dryness while helping to heal wounds. I've noticed fewer pimples and stronger hair after a month of use. Unlike other zinc supplements, this one doesn't make me feel unwell. I wholeheartedly recommend it!
Read More
7.5
Skin disease prevention
493 people found this helpful
This tiny zinc capsule has immense benefits. It plays a vital role in skin cell renewal and collagen formation, helping to combat acne and dryness. Considering its essentiality for health and beauty, I realised maintaining adequate zinc is crucial.
Read More
9
Improved skin health
208 people found this helpful
I purchased zinc to support my immune system during cold season, but I've found it has numerous other benefits for my skin. With zinc, my acne has significantly reduced, and my nails and hair are stronger. I'm very pleased with the results.
Read More
9
Effective acne treatment
201 people found this helpful
I've seen noticeable improvements since taking zinc. My acne-prone skin has cleared up significantly, and my hair has strengthened. I attribute these changes to the zinc, as I haven’t introduced anything new to my routine.
Read More
9
Acne elimination success
178 people found this helpful
Zinc picolinate has been fantastic for my friend suffering from severe acne. After following a doctor's recommendation, they completely eliminated the rash. Such results are rare, making it a valuable supplement.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been recognized for its potential benefits in managing acne due to its anti-inflammatory properties and ability to reduce oil production in the skin. Several studies suggest that zinc supplements may help decrease the severity of acne lesions and improve overall skin health. Additionally, zinc plays a crucial role in the immune system, which can be beneficial in fighting off the bacteria that contribute to acne breakouts. For individuals struggling with moderate acne, opting for zinc supplements or using topical treatments containing zinc might offer some relief and improvement.
That said, while zinc can assist in managing acne, it is not a standalone solution, and results can vary. It’s important to combine any zinc treatment with a comprehensive skincare routine tailored to your skin type and acne severity. Consulting a dermatologist before starting any new supplement or treatment is wise, as they can offer personalized advice and the most effective treatment options for your specific situation.
Based on user reviews, it's common to notice results when taking zinc supplements for acne within a few weeks to two months. Some users have reported significant improvements in their skin condition as early as two weeks after starting the supplement, citing fewer breakouts and clearer skin (Read Review, Read Review). Others noted that while improvements began to appear after a month, complete clarity took longer, reflecting the individual nature of acne treatment (Read Review).
Additionally, users highlighted that consistent use is crucial for sustained benefits. For instance, some individuals found that after continued use spanning several weeks to a couple of months, their acne significantly reduced, along with other skin benefits (Read Review). In general, while some users see rapid results, it may be best to allow at least a month of consistent use to gauge effectiveness.
Scientific research indicates that zinc may offer potential benefits for acne treatment. Several studies have explored its role, suggesting that high doses of dietary zinc could help reduce inflammation associated with acne vulgaris [1]. Other work has shown that oral zinc treatments resulted in moderate to good responses in 40% to 60% of participants suffering from acne rosacea [2], highlighting zinc's potential effectiveness in this area. Moreover, reviews indicate that individuals with acne often exhibit lower zinc levels compared to those without the condition, implying that zinc supplementation may aid in acne management, particularly for inflammatory lesions [16].
Despite the encouraging findings, the specific effectiveness of zinc as a standalone treatment remains unclear. Some studies emphasize that while zinc may complement other treatments, its isolated impact has yet to be fully validated [1]. Concerns regarding gastrointestinal side effects have also been raised [5]. Overall, while the evidence points to zinc as a potentially valuable supplement for acne, particularly in conjunction with other therapies, further rigorous research is essential to clarify its definitive role and optimal usage in acne treatment regimens.
Users have reported a wide range of improvements in their acne and overall skin condition after incorporating zinc supplements into their daily routine. Many reviewers noted significant reductions in acne severity, with some individuals witnessing notable changes as early as two weeks after starting zinc supplementation (Read Review, Read Review) and others mentioning improvements within a month (Read Review). Overall, many users attributed clearer, healthier skin to zinc's role in skin cell renewal and collagen formation, which can be particularly beneficial for those with acne-prone skin (Read Review).
In addition to acne reduction, users experienced additional benefits, such as stronger hair and nails, and improvements in overall skin condition (Read Review, Read Review, Read Review). However, it’s important to note that individual results can vary; some users experienced minimal changes, and others emphasized the importance of a comprehensive skincare routine in conjunction with zinc supplementation (Read Review, Read Review) .
Based on user reviews, combining zinc supplements with other supplements can enhance their effectiveness in managing acne. For instance, one user reported significant improvements in hormonal cystic acne after taking zinc alongside evening primrose oil and vitex, noting visible results within the first month (Read Review). Additionally, another reviewer described a successful acne regimen that included zinc, Pantothenic acid, and pycnogenol, observing marked improvement within a week and continued efficacy with ongoing use (Read Review).
Moreover, some users have reported that integrating zinc with vitamins and a comprehensive skincare routine further supports skin clarity and health. One reviewer mentioned receiving dermatologist advice to take zinc along with vitamins, which resulted in a complete disappearance of their facial rash after two courses (Read Review). Consequently, while individual outcomes may vary, users generally find that pairing zinc with other supplements or skincare measures provides robust support in treating acne and improving overall skin condition.
The optimal dose of zinc for treating acne appears to lean towards higher levels, particularly based on research findings that highlight the effectiveness of high-dose dietary zinc in reducing inflammation associated with acne. One study identified high doses of dietary zinc as a promising option for acne treatment, particularly emphasizing the significance of zinc-binding proteins in inflammatory skin conditions, including acne vulgaris [1]. A systematic review noted that zinc treatments could significantly reduce inflammatory symptoms, indicating that doses adequate to elevate zinc levels in the body may yield positive results for those struggling with acne [5].
While various studies have explored zinc's role in acne management, findings suggest that many treatments utilize either topical applications or supplements that include zinc as part of a combination therapy. Particularly, a study highlighted that patients reported greater improvements in their quality of life when treated with zinc sulphate, underscoring the potential benefits of this mineral [13]. It's recommended that individuals considering zinc supplementation should consult a healthcare provider to establish an effective and safe dosage for their specific skin concerns.
9
Deficiency addressed
7 people found this helpful
This zinc is the best! After tests revealed I had a deficiency causing acne, my doctor prescribed it. I noticed visible effects in two weeks. Always consult a specialist!
9
Clearer skin achieved
3 people found this helpful
Fantastic! After taking this zinc for just two weeks, my skin looks clearer, and I’ve not had any new pimples. I’m thrilled with the results!
9
Clear skin achieved
1415 people found this helpful
Zinc has transformed my skin! It aids in renewing skin cells and collagen formation, reducing acne and dryness while helping to heal wounds. I've noticed fewer pimples and stronger hair after a month of use. Unlike other zinc supplements, this one doesn't make me feel unwell. I wholeheartedly recommend it!
7.5
Skin rejuvenation
77 people found this helpful
Zinc is vital for skin cell renewal and collagen formation. It helps reduce allergic reactions, dryness, and acne. After two months of taking it, my acne has reduced, and my hair has improved in condition.
7.5
Improved skin
9 people found this helpful
So far, I've been using zinc with evening primrose oil and vitex for hormonal cystic acne. I've seen significant improvement after the first month.
9
Improved skin health
208 people found this helpful
I purchased zinc to support my immune system during cold season, but I've found it has numerous other benefits for my skin. With zinc, my acne has significantly reduced, and my nails and hair are stronger. I'm very pleased with the results.
9
Reduced hair loss
41 people found this helpful
I aimed to improve my skin condition, particularly for acne, and I found zinc effective. It regulates oil production well, and I've noticed significantly less hair loss. Even my husband has observed that I no longer leave hair everywhere. Remarkably, my hair roots also stay fresher for longer, allowing me to wash my hair every third day. I had not anticipated such a positive effect.
7.5
Skin support supplement
26 people found this helpful
I used this supplement for problem skin, and I noticed it reduces sebum production, which is beneficial for acne. Zinc picolinate has high bioavailability, and after consistent use, I saw fewer rashes. Although I maintain a comprehensive skincare routine, zinc definitely contributes to improved skin condition and immune support.
0
Ineffective for acne
9 people found this helpful
I would not recommend this zinc form. My girlfriend noticed little change in her acne, and despite taking it for testosterone, studies show picolinate zinc is not effective for increasing serum zinc levels. Other forms may be better.
10
Recipe for acne
23 people found this helpful
If you're struggling with acne, I found an effective regimen: take 1000 mg of Pantothenic acid, 50 mg of zinc picolinate, and 120 mg of pycnogenol daily. I observed significant improvement within a week, and continued use ensures that acne does not return.
9
Acne resolved
130 people found this helpful
After seeking advice from a dermatologist, I began taking zinc along with vitamins. After two courses, my facial rash completely disappeared. This has truly been a lifesaver.
8
Zinc treatment shows promise for acne
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent.
We explored how zinc treatment may help with inflammatory skin conditions like acne vulgaris, rosacea, and hidradenitis suppurativa. These conditions can appear quite similar, which makes diagnosing them a bit tricky. By examining gene expression data across these three disorders, we noticed that certain zinc-binding proteins were consistently elevated in all cases.
Our hypothesis centers around these proteins possibly sequestering zinc, which could promote inflammation due to local zinc deficiency. To investigate this further, we identified high-dose dietary zinc as a potential therapeutic option. This was tested and validated in an acne mouse model, showing promising results for its effectiveness in reducing the inflammation associated with acne.
Although the study specifically highlighted the isolated effect of zinc, it strongly suggests that incorporating high doses of dietary zinc might offer a new avenue for treatment. This could be an encouraging option for those struggling with acne, pointing to a novel approach grounded in scientific findings.
We investigated how zinc treatment affects acne, particularly focusing on its potential benefits for those suffering from acne rosacea. The study observed that zinc sulfate solution at a concentration of 5% played a notable role in reducing the severity of acne rosacea symptoms.
Findings indicated that around 40% to 60% of patients experienced a moderate to good response after using zinc. This suggests that zinc could be helpful for individuals looking for alternatives or supplements in their acne treatment regimen.
However, it's important to acknowledge that while zinc showed positive results, the isolated effect of zinc alone cannot be fully determined. It might have worked in conjunction with other treatment factors, which complicates our understanding of its effectiveness.
Therefore, we emphasize the need for further studies to clarify exactly how zinc contributes to acne treatment outcomes and to evaluate its role alongside other therapies.
8
Zinc effective for acne treatment
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
7
Zinc's role in acne unclear
Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review.
We delved into the effectiveness of oral zinc treatment for acne through a systematic review of randomized clinical trials. The study drew from numerous databases to pinpoint research that examined how zinc—and other nutraceuticals—could potentially alleviate acne symptoms.
Among the 42 studies reviewed, several demonstrated a possible benefit from various vitamins and botanicals, including zinc. Specifically, while zinc therapy was included, it was noted that gastrointestinal side effects were associated with it, which might deter some users. Overall, zinc's effectiveness in reducing acne lesions was not conclusively separated from other treatments, as the results showed mixed findings across different studies.
Therefore, while zinc may play a role in improving acne symptoms, it's essential for users to be aware of the potential adverse effects and the treatment's variability in individual responses. More extensive and well-structured trials are likely needed to clarify zinc's precise impact in treating acne.
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
References
Li L, Hajam I, McGee JS, Tang Z, Zhang Y, et al. Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent. Exp Dermatol. 2024;33:e15145. doi:10.1111/exd.15145
Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4
Akman TC, Yazici M, Atila A, Mertoglu C. Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects. Biol Trace Elem Res. 2024;202:4858. doi:10.1007/s12011-023-04053-9
Li L, Hajam I, McGee JS, Tang Z, Zhang Y, et al. Comparative Transcriptome Analysis of Acne vulgaris, Rosacea, and Hidradenitis Suppurativa Supports High Dose Dietary Zinc as a Therapeutic Agent. medRxiv. 2023. doi:10.1101/2023.11.28.23299152
Shields A, Ly S, Wafae B, Chang YF, Manjaly P, et al. Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review. JAMA Dermatol. 2023;159:1373. doi:10.1001/jamadermatol.2023.3949
Tan YY, Wong LS, Nyam KL, Wittayanarakul K, Zawawi NA, et al. Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using and Its Effect on Acne Vulgaris. Molecules. 2023;28. doi:10.3390/molecules28196749
Xiang Y, Lu J, Mao C, Zhu Y, Wang C, et al. Ultrasound-triggered interfacial engineering-based microneedle for bacterial infection acne treatment. Sci Adv. 2023;9:eadf0854. doi:10.1126/sciadv.adf0854
Towersey L, Correia P, Fajgenbaum Feiges M, Euzébio Gonçalves Junior J, Sant'Anna B, et al. Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study. Clin Cosmet Investig Dermatol. 2023;16:119. doi:10.2147/CCID.S394123
Salah E. Oral Zinc as a Novel Adjuvant and Sparing Therapy for Systemic Isotretinoin in Acne Vulgaris: A Preliminary Comparative Study. J Clin Aesthet Dermatol. 2022;15:58.
Naji HH, Al-Azawi RSA, Ibrahim NJ, Kzar HH. Investigation of the Role of Zn/Cu Index and its Correlation with Physiological Activity of SOD 1 and GRx in Males with Acne Vulgaris. Arch Razi Inst. 2022;77:623. doi:10.22092/ARI.2021.356857.1928
Searle T, Ali FR, Al-Niaimi F. Zinc in dermatology. J Dermatolog Treat. 2022;33:2455. doi:10.1080/09546634.2022.2062282
Poizeau F, Plantier F, Bell H, Moyal-Barracco M. Vulvar Fordyce adenitis: A cohort of 45 women. Ann Dermatol Venereol. 2021;148:221. doi:10.1016/j.annder.2021.04.001
Tolino E, Skroza N, Mambrin A, Proietti I, Bernardini N, et al. An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris. J Clin Aesthet Dermatol. 2021;14:56.
Maillard A, Pastor D, Merat R. Anti-PD-1-Induced Hidradenitis Suppurativa. Dermatopathology (Basel). 2021;8:37. doi:10.3390/dermatopathology8010007
Abendrot M, Płuciennik E, Felczak A, Zawadzka K, Piątczak E, et al. Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations. Int J Mol Sci. 2021;22. doi:10.3390/ijms22041641
Yee BE, Richards P, Sui JY, Marsch AF. Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis. Dermatol Ther. 2020;33:e14252. doi:10.1111/dth.14252