Medical Researches
Moderately Effective
Based on 3 Researches
Zinc's role in insomnia unclearThe effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
Combination therapy complicates zinc analysis
We conducted a double-blind, placebo-controlled study in a long-term care facility in Italy to assess whether nightly supplementation of melatonin, magnesium, and zinc could help improve primary insomnia in elderly residents. A total of 43 participants, mostly in their late 70s, were divided into two groups: one received a combination of these supplements, while the other received a placebo for eight weeks.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
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We tested the effectiveness of a unique nutraceutical product, ElleN®, aimed at alleviating postmenopausal symptoms, particularly sleeplessness due to anxiety and hot flushes. This product contains several natural ingredients, including zinc, but we acknowledge that its effects are evaluated in combination with others. In our study, women experiencing mild to moderate/severe menopausal symptoms took one tablet daily for three months.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
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Zinc promotes sleep in miceZinc-containing yeast extract promotes nonrapid eye movement sleep in mice.
High relevance to insomnia treatment
We explored the effects of zinc on sleep by looking at how it might help with insomnia. In our study, we gave mice a zinc-containing yeast extract and monitored their behavior and brain activity. The results were quite promising.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
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User Reviews
Amazing! I purchased this for my wife, who previously used a more expensive brand. After switching to Now Foods Picolinate Zinc, she noticed significant improvements in her skin regarding hormonal break-outs and found it easier to swallow the capsules. She felt it helped with her anxiety and appetite control, as she is now more aware of when to stop eating. These zinc capsules have worked wonders for her without any side effects. I will definitely buy again!
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Zinc Picolinate aids in stabilising insomnia, depression, and other conditions like menopause. The natural ingredients relieve stress, boost brain function, and improve sleep and mood. The capsules are medium-sized. GABA, a neurotransmitter, enhances sleep quality, particularly during night-time when growth hormone is most released. This formula limits stress effects and ensures deeper, more effective sleep, with an optimal dosage.
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Zinc is effective for stabilising insomnia, depression, and other conditions during menopause. The natural ingredients relieve stress, stimulate brain function, and improve sleep and mood. GABA enhances sleep quality, especially when growth hormone is released at night. This component helps provide deeper, more effective sleep and limits stress factors, with an optimal dosage.
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Zinc stabilises insomnia, depression, and other conditions, notably during menopause. It contains natural ingredients that reduce stress, enhance brain function, and aid in improving sleep and mood. GABA also enhances sleep quality, particularly when growth hormone is released at night. This component limits stress impacts and promotes deeper, more effective sleep with the optimal dosage.
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Zinc supports the immune system and stabilises insomnia, depression, and various conditions, especially in older age. The natural ingredients alleviate stress, boost brain function, and enhance sleep and mood. GABA improves sleep quality when the body releases growth hormone at night. This ingredient limits stress effects and provides deeper, more effective sleep with an optimal dosage.
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