'
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 6 Reviews
8.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc(from 270 mg Zinc Picolinate)
50 mg
455% 

Top Medical Research Studies

9
Zinc reduces migraine symptoms
Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women.
Highly relevant to migraine treatment
This study was designed as a randomized double-blind, placebo-controlled trial to examine how zinc gluconate supplementation might alleviate migraine symptoms in adult women. We followed 60 women, averaging about 35 years old, who either received 15 mg of zinc per day or a placebo for a duration of 12 weeks.

Over the trial, we observed significant improvements in those taking zinc. The frequency of migraine attacks, as well as the duration and severity of the headaches, drastically decreased for participants receiving zinc. We used various assessments, such as a numerical rating scale and the Migraine Disability Assessment test, to evaluate these changes.

Additionally, zinc supplementation showed a notable reduction in levels of low-density lipoprotein (LDL) cholesterol and high-sensitivity C-reactive protein (hs-CRP), both of which are associated with inflammation. However, no significant changes in triglycerides or high-density lipoprotein (HDL) levels were seen. After taking initial values into account, the changes in lipid levels and hs-CRP weren’t significant.

Overall, we found that zinc supplementation can beneficially impact migraine symptoms, reducing their severity and frequency among women. This offers a promising direction for migraine management without the side effects often associated with traditional medications.
Read More
7
Zinc reduces migraine attack frequency
Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial.
Directly assesses zinc for migraines
We aimed to understand how zinc supplementation influences the frequency of migraine attacks. In this structured clinical trial, 80 patients suffering from migraines participated, receiving either zinc sulfate or a placebo over eight weeks.

Our results revealed that those who took zinc experienced a notable decrease in the frequency of their migraine attacks and, to some extent, in headache severity. Specifically, participants on zinc reported 2.55 fewer migraine attacks on average compared to only 0.42 fewer for those on the placebo. However, when we adjusted for certain factors, the reduction in headache severity lost its statistical significance.

It's essential to note that while zinc supplementation appeared to help with attack frequency, other aspects of migraines, such as their duration and daily headache impact, remained unchanged. This suggests that zinc might specifically influence how often migraines occur rather than their intensity or lasting effects. Further research is encouraged to explore varying dosages and longer intervention periods for a more profound understanding of zinc's potential benefits.
Read More
8
Zinc intake linked to fewer migraines
Dietary zinc intake in relation to migraine among adults: a cross sectional study of NHANES 1999-2004.
Direct assessment of zinc’s effect
We investigated the connection between dietary zinc intake and the occurrence of migraines among adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES) collected between 1999 and 2004.

Our findings indicated that higher zinc intake was linked to a lower prevalence of migraines. Participants who consumed more zinc, particularly those in the middle to higher intake groups, experienced fewer migraine episodes compared to those who consumed the least zinc.

Interestingly, we found that age plays a role in this relationship. Specifically, adults aged between 20 and 50 displayed a non-linear association between zinc intake and migraine occurrence, suggesting that age modifies the impact of zinc on migraines. Overall, these results point to the potential benefits of including sufficient zinc in our diets as a preventative measure against migraines.
Read More

Most Useful Reviews

9.5
Improved migraine frequency
Great! It normalises sleep when I take 2 capsules regularly. It has greatly improved my migraines, which now pass in a couple of hours instead of taking half a day. I have also found that PMS and menstruation are easier to endure with regular magnesium intake. Chronic nasal pain has not worsened either. I suspect the magnesium, along with my other supplements, has been beneficial, but I was pleasantly surprised by the result. No allergies or stomach issues, and the quality is excellent.
Read More
9.5
Effective for migraine
I’m a repeat customer of Now Zinc Picolinate! It works well for my migraines and boosts my immune system. Great price and packaging! Love it!
Read More
9.5
Eased migraine attacks
Great! It normalises sleep when I take 2 capsules regularly. It has improved my migraines, passing in a couple of hours now. I feel less crazy during PMS and menstruation. Chronic nasal pain has not worsened. While I can't attribute all the benefits to magnesium alone, it seems to have played a role. No allergies or stomach issues, and the quality is excellent.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
9.5
Zinc may alleviate migraines
A new horizon into the pathobiology, etiology and treatment of migraine.
Study combines zinc with supplements.
We embarked on an investigation into the potential of zinc as a treatment for migraines. The study involved 30 migraine sufferers who were given 75 mg of zinc sulfate daily for six weeks, along with vitamin B-complex and vitamin A or E during the first ten days.

Remarkably, this combination led to a significant improvement in most participants, suggesting that zinc could play a vital role in alleviating migraine symptoms. Zinc's effectiveness may stem from its essential functions in various biological processes, such as supporting the nervous system and regulating mineral balance in the body.

However, it’s important to note that the research combined zinc with other supplements, which makes it challenging to ascertain zinc's isolated effect on migraines. Future studies may benefit from a more controlled approach—perhaps comparing zinc against a placebo or examining its impact in larger groups.

Overall, this exploration opens new avenues for understanding how zinc and other nutrients can contribute to migraine relief, but further research is needed to fully validate these findings.
Read More
9
Zinc reduces migraine symptoms
Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women.
Highly relevant to migraine treatment
This study was designed as a randomized double-blind, placebo-controlled trial to examine how zinc gluconate supplementation might alleviate migraine symptoms in adult women. We followed 60 women, averaging about 35 years old, who either received 15 mg of zinc per day or a placebo for a duration of 12 weeks.

Over the trial, we observed significant improvements in those taking zinc. The frequency of migraine attacks, as well as the duration and severity of the headaches, drastically decreased for participants receiving zinc. We used various assessments, such as a numerical rating scale and the Migraine Disability Assessment test, to evaluate these changes.

Additionally, zinc supplementation showed a notable reduction in levels of low-density lipoprotein (LDL) cholesterol and high-sensitivity C-reactive protein (hs-CRP), both of which are associated with inflammation. However, no significant changes in triglycerides or high-density lipoprotein (HDL) levels were seen. After taking initial values into account, the changes in lipid levels and hs-CRP weren’t significant.

Overall, we found that zinc supplementation can beneficially impact migraine symptoms, reducing their severity and frequency among women. This offers a promising direction for migraine management without the side effects often associated with traditional medications.
Read More
8
Zinc intake linked to fewer migraines
Dietary zinc intake in relation to migraine among adults: a cross sectional study of NHANES 1999-2004.
Direct assessment of zinc’s effect
We investigated the connection between dietary zinc intake and the occurrence of migraines among adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES) collected between 1999 and 2004.

Our findings indicated that higher zinc intake was linked to a lower prevalence of migraines. Participants who consumed more zinc, particularly those in the middle to higher intake groups, experienced fewer migraine episodes compared to those who consumed the least zinc.

Interestingly, we found that age plays a role in this relationship. Specifically, adults aged between 20 and 50 displayed a non-linear association between zinc intake and migraine occurrence, suggesting that age modifies the impact of zinc on migraines. Overall, these results point to the potential benefits of including sufficient zinc in our diets as a preventative measure against migraines.
Read More
8
Zinc intake linked to migraine
Dietary zinc intake and migraine in adults: a cross-sectional analysis of the National Health and Nutrition Examination Survey 1999-2004.
Directly addresses zinc and migraine
We explored the relationship between dietary zinc intake and migraine by analyzing data from the National Health and Nutrition Examination Survey conducted between 1999 and 2004. This cross-sectional study involved over 11,000 participants, with 20.2% reporting migraine attacks.

Our findings revealed an interesting trend: individuals who consumed higher amounts of zinc appeared to have a lower likelihood of experiencing migraines. Specifically, people in the highest zinc intake category were significantly less likely to report migraines compared to those with the lowest intake. These results suggest that increasing zinc consumption might be beneficial for migraine prevention.

However, it's important to note that while the study indicates an association between zinc intake and reduced migraine incidence, it doesn't definitively establish that zinc directly affects migraine pathophysiology. Thus, further research would be necessary to clarify the role of zinc in migraine management.

Overall, we've shed some light on how dietary zinc might play a role in migraines, suggesting that paying attention to zinc intake could be worthwhile for those affected by this condition.
Read More
7
Zinc shows promise for migraines
Zinc Administration Favorably Affects Prophylactic Therapy-refractory Migraine Attacks: A Case Series.
Highly relevant to migraine treatment
We explored the potential of zinc supplementation in individuals who experience migraines that don’t respond to traditional prophylactic therapies. Our focus was on four patients whose migraine symptoms had proven stubbornly resistant to standard treatments.

After adding zinc to their regimen, these patients reported a notable reduction in both the frequency and the severity of their headache episodes. These findings suggest that zinc may offer a new hope for those struggling with chronic migraines, particularly when existing medications fail to provide relief.

Although this small case series is encouraging, we recognize that further research is necessary to fully understand zinc's efficacy in treating migraines. Larger studies will help us determine how zinc can be integrated into migraine management strategies more broadly.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.7
9.5
Improved migraine frequency
Great! It normalises sleep when I take 2 capsules regularly. It has greatly improved my migraines, which now pass in a couple of hours instead of taking half a day. I have also found that PMS and menstruation are easier to endure with regular magnesium intake. Chronic nasal pain has not worsened either. I suspect the magnesium, along with my other supplements, has been beneficial, but I was pleasantly surprised by the result. No allergies or stomach issues, and the quality is excellent.
Read More
9.5
Effective for migraine
I’m a repeat customer of Now Zinc Picolinate! It works well for my migraines and boosts my immune system. Great price and packaging! Love it!
9.5
Eased migraine attacks
Great! It normalises sleep when I take 2 capsules regularly. It has improved my migraines, passing in a couple of hours now. I feel less crazy during PMS and menstruation. Chronic nasal pain has not worsened. While I can't attribute all the benefits to magnesium alone, it seems to have played a role. No allergies or stomach issues, and the quality is excellent.
Read More
9.5
Migraines less frequent
Great! It normalises sleep with a regular intake of 2 capsules. It has improved my migraines, making them pass in a couple of hours. I feel calmer during PMS and menstruation, and chronic nasal pain has not worsened. While I also take other supplements, magnesium seems beneficial. I'm delighted with the quality and experienced no side effects.
Read More
8.8
Migraine intensity reduced
I’ve taken zinc before and found it helped with colds. I don’t typically use supplements, but after a bad cold, I tried a capsule daily. Since then, I’ve noticed a significant reduction in the frequency and intensity of my migraines. My migraines used to last for days, but I’ve had only one bad headache recently, and I manage activities without vomiting. I’m hopeful the zinc is positively influencing my overall wellbeing too.
Read More
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