We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
7.5
Easier to sleep
20 people found this helpful
Positive product results! Before I shop for supplements, I spend hours researching them. After some blood work, my doctor advised me to take a magnesium supplement due to my high inflammation levels from Fibromyalgia. I chose this brand as there were no fillers, and it met my needs at a reasonable price. The results have been surprising; I feel better most days, with my chronic pain less intense. Importantly, I'm finding it easier to fall asleep, which is crucial for an insomniac like me. I happily recommend this product. You'll be amazed. You need magnesium!
Read More
9
Reduces insomnia
Great sleep! Magnesium Malate enhances energy production, protects muscle function, aids calcium absorption, combats muscle weakness, improves memory, and reduces insomnia.
Read More
7.5
Mineral deficiency cure
1 people found this helpful
I tried various remedies for insomnia but realised I lacked minerals. Magnesium malate has proven effective in combating my insomnia.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
Positive product results! Before I shop for supplements, I spend hours researching them. After some blood work, my doctor advised me to take a magnesium supplement due to my high inflammation levels from Fibromyalgia. I chose this brand as there were no fillers, and it met my needs at a reasonable price. The results have been surprising; I feel better most days, with my chronic pain less intense. Importantly, I'm finding it easier to fall asleep, which is crucial for an insomniac like me. I happily recommend this product. You'll be amazed. You need magnesium!
Read More
9
Reduces insomnia
Great sleep! Magnesium Malate enhances energy production, protects muscle function, aids calcium absorption, combats muscle weakness, improves memory, and reduces insomnia.
Read More
7.5
Mineral deficiency cure
1 people found this helpful
I tried various remedies for insomnia but realised I lacked minerals. Magnesium malate has proven effective in combating my insomnia.
Read More
7.5
Easier sleep aid
Magnesium malate is well absorbed in the body. I drink it at night with vitamin C to help manage my insomnia, and I've found it helps me fall asleep more easily.
Read More
7.5
Protects against insomnia
Magnesium is essential for the body; it safeguards against insomnia, aids muscle recovery, and promotes relaxation for sleep.
Read More
Frequently Asked Questions
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted as a natural remedy for improving sleep quality and managing insomnia. This essential mineral plays a crucial role in various bodily functions, including the regulation of neurotransmitters that send signals throughout the nervous system and brain. Some studies suggest that magnesium may assist in promoting relaxation by helping to regulate melatonin, a hormone responsible for sleep-wake cycles. Additionally, it may help reduce anxiety and stress, which are common culprits of sleep disturbances.
While many people report improved sleep after incorporating magnesium supplements or magnesium-rich foods—like leafy greens, nuts, and whole grains—into their diets, the scientific evidence is mixed. More research is needed to definitively establish its effectiveness in treating insomnia. If you're considering magnesium supplements, it's always best to consult with a healthcare professional to determine the appropriate dosage and ensure that it won’t interact with any medications you may be taking. Overall, while magnesium may offer some benefits for sleep, it is most effective when used as part of a comprehensive approach to improving sleep hygiene.
Based on user reviews, the time it typically takes to see results from taking magnesium malate for insomnia varies. Some users have reported experiencing improvements in their ability to fall asleep relatively quickly after starting the supplement, often within days. For instance, one user noted that their experience with magnesium malate helped them fall asleep more easily during the night (Read Review). Another reviewer indicated that the supplement was effective in combating their insomnia, suggesting positive results were noticed promptly after addressing a mineral deficiency (Read Review).
While many users seemed to achieve benefits fairly quickly, it's important to recognize that individual experiences can differ based on factors such as dosage and personal health. Overall, if you're considering magnesium malate for insomnia, some users suggest that improvements can be felt within just a few days of consistent use.
The evidence supporting magnesium supplementation for insomnia is compelling but not without its caveats. Multiple studies have shown that magnesium can play a beneficial role in improving sleep quality and mitigating insomnia symptoms across various populations. For instance, a systematic review of clinical trials indicated that out of eight studies focused on sleep-related outcomes, five found positive effects of magnesium supplementation on sleep quality [3]. Additionally, a double-blind trial involving older adults suggested significant enhancements in sleep efficiency and insomnia severity with magnesium supplementation [8].
However, it's important to note that some studies have produced mixed results, and the effects of magnesium may vary depending on individual conditions and the presence of other factors, such as pain and hormonal changes [2]. Moreover, isolating magnesium's effects from those of other compounds it’s often combined with in supplements can be challenging [5]. Overall, while magnesium seems to be a promising option for those struggling with insomnia, further large-scale studies and targeted research are necessary to solidify its role as an effective standalone treatment for sleep disorders.
Based on user reviews, many individuals have reported significant improvements in their symptoms related to sleep and insomnia after starting magnesium malate. For example, one user noted that it effectively combats their insomnia after discovering they were lacking essential minerals (Read Review). Additionally, another reviewer remarked that magnesium malate enhances their ability to fall asleep more easily when taken at night, often combining it with vitamin C for better results (Read Review).
Furthermore, some users have found that magnesium malate not only helps with insomnia but also supports overall well-being by enhancing energy production, protecting muscle function, and even assisting with memory improvement (Read Review). While these anecdotal experiences highlight the potential benefits of magnesium malate, it's crucial to remember that individual results may vary based on personal health and dosage. Thus, if insomnia is a concern, magnesium malate might be worth considering, but results can differ from person to person.
Users have reported positive experiences when combining magnesium malate with other supplements to manage insomnia. For instance, one reviewer noted that they take magnesium malate at night along with vitamin C, which they found effective in helping them fall asleep more easily (Read Review). This combination appears to enhance the sleep-promoting effects of magnesium malate, indicating that pairing it with complementary supplements may yield better results for some individuals.
Additionally, another user highlighted the effectiveness of magnesium malate in addressing their insomnia after realizing they were deficient in essential minerals (Read Review). This suggests that incorporating magnesium malate into a broader supplementation regimen may not only target sleep issues but also support overall health. Overall, users seem to appreciate the benefits of magnesium malate, especially when used in conjunction with other supplements, emphasizing the potential for synergistic effects in improving sleep quality.
When it comes to using magnesium to tackle insomnia, research suggests that up to 500 mg daily can yield promising benefits. A study focusing on older adults found significant improvements in sleep quality and insomnia severity with a daily dosage of 500 mg over eight weeks, indicating that this level may effectively enhance sleep efficiency and overall restfulness [8]. Similarly, another analysis noted that magnesium could play a beneficial role in alleviating insomnia symptoms, particularly when assessed across various studies, though optimal dosages may vary depending on individual circumstances and additional factors [3].
While the dosage of 500 mg seems favorable, the effectiveness of magnesium can be influenced by other elements such as age, concurrent health issues, and overall magnesium levels within an individual's diet [6]. It's crucial to consider these factors when determining the right magnesium intake to potentially improve sleep quality. Consulting with a healthcare provider can help tailor the dosage to individual needs, ensuring a safe and effective approach to managing insomnia.
7.5
Easier sleep aid
Magnesium malate is well absorbed in the body. I drink it at night with vitamin C to help manage my insomnia, and I've found it helps me fall asleep more easily.
7.5
Mineral deficiency cure
1 people found this helpful
I tried various remedies for insomnia but realised I lacked minerals. Magnesium malate has proven effective in combating my insomnia.
9
Reduces insomnia
Great sleep! Magnesium Malate enhances energy production, protects muscle function, aids calcium absorption, combats muscle weakness, improves memory, and reduces insomnia.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
9
Magnesium shows potential insomnia benefits
The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. doi:10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. doi:10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. doi:10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. doi:10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. doi:10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. doi:10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.