We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
10
First effective solution
5 people found this helpful
This product truly works! After hearing about its benefits for insomnia, I ordered it, having suffered for years. I tried everything from sleeping pills to meditation, with no success. This was the first remedy that worked for me long-term and isn’t addictive, which is a massive plus. As a bartender, I also find it helps relieve muscle cramps after long hours on my feet.
Read More
0
Causes insomnia
3 people found this helpful
Inexplicably, this formulation causes severe insomnia for me, the opposite effect of magnesium supplements. I've experimented with its elimination and reinstatement due to my scepticism, but each time it keeps me awake for hours at night. I'm unsure if it's the potassium, but I had to discard the rest. I’ll return to magnesium for muscle cramps and sleep.
Read More
9
Improved sleep quality
1 people found this helpful
After using the poiyema, my chronic fatigue, insomnia, and heart pain improved significantly. Breathing became easier, and heart function enhanced. I found it also helps with arrhythmias.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
This product truly works! After hearing about its benefits for insomnia, I ordered it, having suffered for years. I tried everything from sleeping pills to meditation, with no success. This was the first remedy that worked for me long-term and isn’t addictive, which is a massive plus. As a bartender, I also find it helps relieve muscle cramps after long hours on my feet.
Read More
0
Causes insomnia
3 people found this helpful
Inexplicably, this formulation causes severe insomnia for me, the opposite effect of magnesium supplements. I've experimented with its elimination and reinstatement due to my scepticism, but each time it keeps me awake for hours at night. I'm unsure if it's the potassium, but I had to discard the rest. I’ll return to magnesium for muscle cramps and sleep.
Read More
9
Improved sleep quality
1 people found this helpful
After using the poiyema, my chronic fatigue, insomnia, and heart pain improved significantly. Breathing became easier, and heart function enhanced. I found it also helps with arrhythmias.
Read More
9
Good sleep aid
Excellent composition that supports good sleep and the nervous system. I take it with melatonin for chronic insomnia.
Read More
9
Instant relief
Super! I take two capsules at night, and they work instantly. I really liked it, particularly for insomnia.
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted as a natural remedy for improving sleep quality and managing insomnia. This essential mineral plays a crucial role in various bodily functions, including the regulation of neurotransmitters that send signals throughout the nervous system and brain. Some studies suggest that magnesium may assist in promoting relaxation by helping to regulate melatonin, a hormone responsible for sleep-wake cycles. Additionally, it may help reduce anxiety and stress, which are common culprits of sleep disturbances.
While many people report improved sleep after incorporating magnesium supplements or magnesium-rich foods—like leafy greens, nuts, and whole grains—into their diets, the scientific evidence is mixed. More research is needed to definitively establish its effectiveness in treating insomnia. If you're considering magnesium supplements, it's always best to consult with a healthcare professional to determine the appropriate dosage and ensure that it won’t interact with any medications you may be taking. Overall, while magnesium may offer some benefits for sleep, it is most effective when used as part of a comprehensive approach to improving sleep hygiene.
Based on user reviews, many people have experienced improvements in their insomnia relatively quickly after starting this supplement. Some users report noticeable effects almost immediately, with one reviewer saying it worked "instantly" after taking two capsules at night for insomnia Read Review. Additionally, another user noted that they began to sleep well after struggling with insomnia, indicating a short time frame for improvement Read Review.
Several reviews highlight the supplement's ability to relieve insomnia, muscle tension, and promote overall relaxation, suggesting that users often notice benefits within weeks (Read Review, Read Review). In summary, while individual experiences may vary, a range of users report seeing results from this supplement for insomnia quickly, sometimes within a day to a few weeks.
Research suggests that magnesium supplementation could be effective in alleviating insomnia, but the evidence is somewhat mixed. In a controlled trial involving diabetic patients, magnesium, either alone or combined with potassium, significantly improved sleep quality and hormone levels related to sleep (cortisol and melatonin) [1]. Furthermore, a systematic review of 15 studies indicated that magnesium supplementation generally led to better sleep quality in most trials, although the results varied and some studies did not find significant benefits [3]. Overall, magnesium appears to be a promising option for improving insomnia symptoms, particularly for individuals with low baseline magnesium levels.
Another study focused on older adults reported significant improvements in sleep efficiency and insomnia severity with magnesium supplementation, contributing to a more favorable assessment of its benefits for this demographic [8]. While the findings support the potential role of magnesium in managing sleep disturbances, it's worth noting that many studies included other variables that could influence outcomes. The need for more large-scale, randomized trials remains, but magnesium could be an accessible addition to a sleep improvement regimen for those struggling with insomnia.
Users have reported a variety of improvements in their symptoms after using this supplement, particularly in relation to insomnia, muscle tension, and overall relaxation. Many individuals noted significant alleviation of chronic fatigue and sleep disturbances, with one user experiencing substantial improvement in heart function and breathing alongside their insomnia relief Read Review. Multiple reviewers mentioned using it in conjunction with melatonin for chronic insomnia, which suggests a supportive effect on sleep quality Read Review.
Reviewers often highlighted the supplement's effectiveness nearly immediately, with one person declaring it worked "instantly" for their insomnia Read Review. Others noted improvements within a month, including the resolution of leg cramps and restful nights Read Review. Overall, users report benefits ranging from improved sleep to reduced muscle cramps and improved cardiovascular function, indicating a versatile remedy for various conditions Read Review. While results can vary from person to person, the collective experiences suggest that many have found significant relief and enhancement of well-being with this supplement.
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other sleep aids, notably melatonin. One user specifically mentioned taking the supplement alongside melatonin to address chronic insomnia, highlighting the complementary effects of the two products on sleep quality Read Review. This combination seems to enhance overall effectiveness, as users are finding greater relief from insomnia symptoms when utilizing multiple aids.
In addition to melatonin, users also reported improvements in restless leg syndrome, muscle tension, and overall relaxation when using the supplement, indicating it may work synergistically with other interventions to address insomnia and its related symptoms Read Review. Overall, the anecdotal evidence suggests that this supplement can be effectively paired with other products to enhance sleep quality and alleviate insomnia, providing a multifaceted approach to improving sleep and relaxation.
While there isn't a universally agreed-upon optimal dose of magnesium for treating insomnia, several studies suggest that a dosage of 500 mg per day may be effective, especially for older adults. In one clinical trial involving elderly participants, daily supplementation of 500 mg led to significant improvements in sleep efficiency and insomnia severity over an eight-week period [8]. Another study indicated that magnesium could potentially benefit post-surgical patients in reducing insomnia, though specific dosages were not highlighted [2].
Moreover, systematic reviews discussing magnesium's role in insomnia show trends toward improved sleep quality, particularly in those who may have low magnesium levels. However, because the research is varied and still evolving, it's essential to approach magnesium supplementation cautiously and preferably under medical supervision. For those considering magnesium as a natural remedy, starting with around 300 to 500 mg daily while monitoring for any effects or side effects is a reasonable approach [3].
9
Instant relief
Super! I take two capsules at night, and they work instantly. I really liked it, particularly for insomnia.
7.5
Sleep restoration
1 people found this helpful
Sent this to my mother. The quality is excellent, with optimal ingredients for the elderly. She has begun to sleep well after suffering from insomnia.
9
Cured insomnia
1 people found this helpful
This supplement is wonderful! It replenished my potassium and magnesium levels in a month. My insomnia is gone, and no more night cramps in my legs.
7.5
Helps with insomnia
1 people found this helpful
Very helpful for restless leg syndrome! It also aids in insomnia and promotes general relaxation. A great product, used by both my husband and me.
9
Improved sleep quality
1 people found this helpful
After using the poiyema, my chronic fatigue, insomnia, and heart pain improved significantly. Breathing became easier, and heart function enhanced. I found it also helps with arrhythmias.
9
Good sleep aid
Excellent composition that supports good sleep and the nervous system. I take it with melatonin for chronic insomnia.
7.5
Relieves insomnia
Magnesium and potassium are vital for cell and tissue health, especially in maintaining cardiovascular function and muscle contraction. Taurine supports neuromuscular well-being. This supplement has notably relieved my insomnia and muscle tension. The symptoms like muscle cramps, anxiety, and fatigue suggest a deficiency in these minerals. The capsules are easy to swallow, the packaging is ample, and the quality is excellent. I highly recommend it! If my review was helpful, please click Yes. Thank you!
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. doi:10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. doi:10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. doi:10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. doi:10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. doi:10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. doi:10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.
Okamoto T, Lo YP, Khaing IK, Inoue S, Tada A, et al. The Association of Sodium or Potassium Intake Timing with Athens Insomnia Scale Scores: A Cross-Sectional Study. Nutrients. 2024;17. doi:10.3390/nu17010148
Ko CH, Koon CM, Yu SL, Lee KY, Lau CB, et al. Hypnotic effects of a novel anti-insomnia formula on Drosophila insomnia model. Chin J Integr Med. 2016;22:335. doi:10.1007/s11655-014-1625-1
Iacovides S, Avidon I, Bentley A, Baker FC. Diclofenac potassium restores objective and subjective measures of sleep quality in women with primary dysmenorrhea. Sleep. 2009;32:1019.
Zhai W, Tang R, Gao Y, Su H, Mao H, et al. Efficacy and associated neurotransmitters of digital cognitive behavior therapy for atopic dermatitis: A comparative effectiveness research. Asian Pac J Allergy Immunol. 2023. doi:10.12932/AP-100223-1542