Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.6
USERS' SCORE
Good
Based on 5 Reviews
8.8
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg
†
Top Medical Research Studies
9.5
Potassium channels induce migraines
We explored the question of whether levcromakalim, a potassium channel opener, can induce migraine attacks in individuals already treated with erenumab, a CGRP receptor antibody. In a double-blind, placebo-controlled study, participants received injections of both levcromakalim and placebo to compare their effects on migraine frequency.
Our findings revealed that levcromakalim led to significantly more migraine attacks within 12 hours compared to placebo, with 88% of participants experiencing attacks after the potassium infusion. This suggests that potassium channels can trigger migraines independently of CGRP activation.
Our findings revealed that levcromakalim led to significantly more migraine attacks within 12 hours compared to placebo, with 88% of participants experiencing attacks after the potassium infusion. This suggests that potassium channels can trigger migraines independently of CGRP activation.
Read More
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
8
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.
Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
Most Useful Reviews
10
No migraines at all
10 people found this helpful
I used to suffer from numerous migraines, but since starting this product, I haven't had any. I take it twice daily.
Read More
10
No migraines reported
4 people found this helpful
I haven't experienced any headaches for three weeks since I began taking two capsules twice daily. I haven't had a migraine in that time, which means I've avoided pharmaceuticals as well. How fantastic is that!
Read More
9
No headaches reported
My husband suffers from high blood pressure and migraines but hasn't complained of a headache since he started taking the supplement.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.6
- All Researches
9.5
Potassium channels induce migraines
We explored the question of whether levcromakalim, a potassium channel opener, can induce migraine attacks in individuals already treated with erenumab, a CGRP receptor antibody. In a double-blind, placebo-controlled study, participants received injections of both levcromakalim and placebo to compare their effects on migraine frequency.
Our findings revealed that levcromakalim led to significantly more migraine attacks within 12 hours compared to placebo, with 88% of participants experiencing attacks after the potassium infusion. This suggests that potassium channels can trigger migraines independently of CGRP activation.
Our findings revealed that levcromakalim led to significantly more migraine attacks within 12 hours compared to placebo, with 88% of participants experiencing attacks after the potassium infusion. This suggests that potassium channels can trigger migraines independently of CGRP activation.
Read More
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.
Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.
This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.
This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More
9
We examined how magnesium oxide (MgO), both alone and with riboflavin, helps prevent migraines in pregnant individuals. This retrospective study included 203 patients treated between 2015 and 2020, analyzing outcomes such as migraine frequency, severity, and duration.
We found that both treatment options reduced migraines significantly, with 77% of participants experiencing improvement in associated symptoms. The results indicate that magnesium oxide can be an effective option for managing migraines during pregnancy, making it a potential consideration for expectant mothers suffering from this condition.
We found that both treatment options reduced migraines significantly, with 77% of participants experiencing improvement in associated symptoms. The results indicate that magnesium oxide can be an effective option for managing migraines during pregnancy, making it a potential consideration for expectant mothers suffering from this condition.
Read More
9
Exploring TRESK's impact on migraine
We examined how TRESK potassium channels could play a role in managing migraine pain. Using both in-vivo and ex-vivo rat models, we tested different activation methods and found that cloxyquin, a TRESK activator, significantly reduced pain and the associated chemical markers linked to migraines.
Although combining it with sumatriptan showed promising results in lab settings, this didn't translate to the animal models. Our findings suggest that targeting TRESK channels might be a viable method for alleviating migraine symptoms.
Although combining it with sumatriptan showed promising results in lab settings, this didn't translate to the animal models. Our findings suggest that targeting TRESK channels might be a viable method for alleviating migraine symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
10
No migraines at all
10 people found this helpful
I used to suffer from numerous migraines, but since starting this product, I haven't had any. I take it twice daily.
Read More
10
No migraines reported
4 people found this helpful
I haven't experienced any headaches for three weeks since I began taking two capsules twice daily. I haven't had a migraine in that time, which means I've avoided pharmaceuticals as well. How fantastic is that!
Read More
9
No headaches reported
My husband suffers from high blood pressure and migraines but hasn't complained of a headache since he started taking the supplement.
Read More
9
Migraine relief!
Thank you. This is very effective medicine for me. It helps with my migraine, and I feel much better. Thanks a lot.
Read More
7.5
Helps fight migraines
I love him dearly. This product helps fight migraines effectively.
Read More
Frequently Asked Questions
10
No migraines reported
4 people found this helpful
I haven't experienced any headaches for three weeks since I began taking two capsules twice daily. I haven't had a migraine in that time, which means I've avoided pharmaceuticals as well. How fantastic is that!
10
No migraines at all
10 people found this helpful
I used to suffer from numerous migraines, but since starting this product, I haven't had any. I take it twice daily.
9
Migraine relief!
Thank you. This is very effective medicine for me. It helps with my migraine, and I feel much better. Thanks a lot.
9
No headaches reported
My husband suffers from high blood pressure and migraines but hasn't complained of a headache since he started taking the supplement.
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.
Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.
This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.
This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
7
We explored the role of magnesium as a potential treatment for migraines through a review of existing literature. Migraines can be intense and debilitating, impacting many individuals' day-to-day lives. Our focus was on understanding whether supplementing magnesium could help in preventing or managing these attacks.
Some studies suggest that low levels of magnesium may be linked to more frequent or severe migraine episodes. When people suffer from migraines, inflammation and oxidative stress might contribute to their pain, and magnesium appears to play a role in helping regulate these processes. By supporting brain health and energy metabolism, magnesium could potentially mitigate some of the triggers associated with migraines.
Although the evidence does point to benefits from magnesium supplementation, we noted that more extensive, well-controlled studies are necessary to draw firm conclusions. Overall, while magnesium shows promise, it may not be a standalone solution and could work best in combination with other treatments.
Some studies suggest that low levels of magnesium may be linked to more frequent or severe migraine episodes. When people suffer from migraines, inflammation and oxidative stress might contribute to their pain, and magnesium appears to play a role in helping regulate these processes. By supporting brain health and energy metabolism, magnesium could potentially mitigate some of the triggers associated with migraines.
Although the evidence does point to benefits from magnesium supplementation, we noted that more extensive, well-controlled studies are necessary to draw firm conclusions. Overall, while magnesium shows promise, it may not be a standalone solution and could work best in combination with other treatments.
7
We observed that magnesium is often mentioned in discussions about effective treatments for migraines. This mineral plays a vital role in many bodily functions, and its potential to alleviate migraine symptoms is supported by anecdotal evidence.
Our analysis points out that while magnesium is particularly noted for its benefits, the details surrounding its standalone effectiveness in managing migraines remain unclear. It seems to work best when combined with lifestyle changes such as stress management and sleep hygiene, as well as with dietary adjustments that avoid common migraine triggers.
We understand that people looking for relief from migraines may find hope in using magnesium supplements. However, it's essential to highlight that in the broader context of migraine treatments, magnesium alone may not completely resolve the issue for everyone. So, while some individuals report improvements, it's not a one-size-fits-all solution.
Our analysis points out that while magnesium is particularly noted for its benefits, the details surrounding its standalone effectiveness in managing migraines remain unclear. It seems to work best when combined with lifestyle changes such as stress management and sleep hygiene, as well as with dietary adjustments that avoid common migraine triggers.
We understand that people looking for relief from migraines may find hope in using magnesium supplements. However, it's essential to highlight that in the broader context of migraine treatments, magnesium alone may not completely resolve the issue for everyone. So, while some individuals report improvements, it's not a one-size-fits-all solution.
8
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.
Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
7
Magnesium shows potential in migraines
We examined how magnesium can play a role in reducing migraine episodes. Various studies focusing on both adults and children have explored this possibility, particularly looking at dietary supplements that contain magnesium.
The findings suggest that specific doses of magnesium may indeed help to decrease headache frequency and intensity. This is particularly promising for those who suffer from recurrent migraines, revealing a potential avenue for relief beyond traditional medications.
Although the overall effectiveness can vary from person to person, the evidence we've gathered indicates that incorporating magnesium as part of a treatment plan could be beneficial.
We acknowledge that while magnesium shows promise, ongoing research is needed to better understand how it works and to optimize its use in migraine management.
The findings suggest that specific doses of magnesium may indeed help to decrease headache frequency and intensity. This is particularly promising for those who suffer from recurrent migraines, revealing a potential avenue for relief beyond traditional medications.
Although the overall effectiveness can vary from person to person, the evidence we've gathered indicates that incorporating magnesium as part of a treatment plan could be beneficial.
We acknowledge that while magnesium shows promise, ongoing research is needed to better understand how it works and to optimize its use in migraine management.
References
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- Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. 10.1007/s11916-025-01358-3
- Hajhashemy Z, Golpour-Hamedani S, Eshaghian N, Sadeghi O, Khorvash F, et al. Practical supplements for prevention and management of migraine attacks: a narrative review. Front Nutr. 2024;11:1433390. 10.3389/fnut.2024.1433390
- Talandashti MK, Shahinfar H, Delgarm P, Jazayeri S. Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials. Neurol Sci. 2025;46:651. 10.1007/s10072-024-07794-0
- Gazerani P, Papetti L, Dalkara T, Cook CL, Webster C, et al. The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis. Nutrients. 2024;16. 10.3390/nu16142222
- Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. 10.1111/imj.16314
- Kurhade PI, Kodape SM, Das A, Bansod PG. Synergistic action of sumatriptan delivery and targeting magnesium deficiency using green, pH-responsive MgO nanoparticles synthesized from mahua flower extracts. Environ Sci Pollut Res Int. 2023. 10.1007/s11356-023-30648-9
- Umemoto KK, Tawk K, Mazhari N, Abouzari M, Djalilian HR. Management of Migraine-Associated Vestibulocochlear Disorders. Audiol Res. 2023;13:528. 10.3390/audiolres13040047
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- Shenoy NN, Gheewala GK, Kedambadi R, Pai S, Zulfikli KM, et al. Can Serum Magnesium Level and Visual Evoked Potentials (P100) be a Predictive in Migraineurs?: Evidence Based Study. Neurol India. 2023;71:463. 10.4103/0028-3886.378668
- Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. 10.1097/MOO.0000000000000908
- Pawar V, Ashraf H, Dorsala S, Mary P, Hameed N, et al. Motorist's Vestibular Disorientation Syndrome (MVDS)-Proposed Diagnostic Criteria. J Pers Med. 2023;13. 10.3390/jpm13050732
- Hoshino MT, Bochio MG, Spagnol Bonache J, Ludwig L, Leandro de Campos M, et al. Plasma and erythrocyte magnesium levels: from validation of the method to analysis in volunteers diagnosed to migraine. Magnes Res. 2022;35:51. 10.1684/mrh.2022.0502
- Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. 10.4103/0028-3886.359247
- Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
- Mazza GR, Solorio C, Stek AM, Kalayjian LA, Wilson ML, et al. Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy. Arch Gynecol Obstet. 2023;308:1749. 10.1007/s00404-022-06872-y
- Ariyanfar S, Razeghi Jahromi S, Togha M, Ghorbani Z. Review on Headache Related to Dietary Supplements. Curr Pain Headache Rep. 2022;26:193. 10.1007/s11916-022-01019-9
- Guerrero-Toro C, Koroleva K, Ermakova E, Gafurov O, Abushik P, et al. Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain. Int J Mol Sci. 2022;23. 10.3390/ijms23031529
- Matin H, Taghian F, Chitsaz A. Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial. Neurol Sci. 2022;43:4413. 10.1007/s10072-021-05843-6
- Karim MR, Bhattacharjee M, Islam MS, Banerjee S, Hossain S, et al. Relation between Serum Magnesium Level and Migraine. Mymensingh Med J. 2021;30:301.
- Torun IE, Kilinc YB, Kilinc E, Töre F. TRESK channel activation ameliorates migraine-like pain via modulation of CGRP release from the trigeminovascular system and meningeal mast cells in experimental migraine models. Life Sci. 2024;357:123091. 10.1016/j.lfs.2024.123091
- Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Melchior AG, et al. Hypersensitivity to BK channel opening in persistent post-traumatic headache. J Headache Pain. 2024;25:102. 10.1186/s10194-024-01808-0
- Raffaelli B, Do TP, Chaudhry BA, Amin FM, Ashina H, et al. Activation of ATP-sensitive potassium channels triggers migraine attacks independent of calcitonin gene-related peptide receptors: a randomized placebo-controlled trial. Cephalalgia. 2024;44:3331024231222916. 10.1177/03331024231222916
- Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Burstein R, et al. Hypersensitivity to opening of ATP-sensitive potassium channels in post-traumatic headache. Cephalalgia. 2023;43:3331024231210930. 10.1177/03331024231210930
- Rothrock JF, Mar KR, Yaksh TL, Golbeck A, Moore AC. Cerebrospinal fluid analyses in migraine patients and controls. Cephalalgia. 1995;15:489.
- Martínez F, Castillo J, Leira R, Prieto JM, Lema M, et al. Taurine levels in plasma and cerebrospinal fluid in migraine patients. Headache. 1993;33:324.
