We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
Most Useful Reviews
7.5
Reduced acne
150 people found this helpful
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
Read More
9
Lasting results
100 people found this helpful
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
Read More
9
Less acne scars
80 people found this helpful
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
8
Omega-3 effects on acne studied
The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris.
We investigated whether omega-3 fatty acids could help manage acne by influencing gut bacteria. Over 12 weeks, untreated acne patients were divided into two groups: one received omega-3 supplements while the other didn’t. We also tested in rats with an acne model. The findings indicated that omega-3 increased gut bacteria diversity and enhanced beneficial bacteria linked to anti-inflammatory effects. However, despite these promising changes, we did not observe a significant overall impact on acne improvement in patients.
Read More
8
Omega-3 improves acne symptoms
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
Read More
9
Lasting results
100 people found this helpful
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
Read More
9
Less acne scars
80 people found this helpful
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
Read More
9
Helps with acne
17 people found this helpful
This omega-3 supplement offers great value for money. It aids collagen preservation and improves skin conditions like acne, whilst promoting heart health and overall well-being. Regular intake is crucial for benefits, especially for mental health and maintaining a positive outlook.
Read More
0
Worsened acne
5 people found this helpful
I ordered this Omega based on good reviews, but it worsened my skin condition with subcutaneous acne. Discontinuing the product improved my skin, and I experienced severe stomach pain as well. I do not recommend it.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Research on the effects of Omega-3 fish oil on acne suggests that it may offer some benefits, particularly due to its anti-inflammatory properties. Omega-3 fatty acids, which are found in fish oil, are known to help reduce inflammation in the body, and since acne is often associated with inflammatory processes, some individuals may experience a decrease in the severity or frequency of their breakouts. Additionally, Omega-3s can help improve skin hydration and may support overall skin health, which can be beneficial for those dealing with acne-prone skin.
However, while some studies have shown promising results, the evidence is not definitive enough to make Omega-3 fish oil a guaranteed solution for acne. It is also worth noting that dietary changes and supplements should complement a comprehensive skincare regimen tailored to individual skin types and needs. If you're considering adding Omega-3 supplements to your routine for acne management, it's a good idea to consult with a healthcare professional to ensure it aligns with your overall health goals and skincare plan.
Based on user reviews, the timeframe for seeing results from Omega-3 supplements in relation to acne can vary significantly. Some users report noticeable improvements in their skin condition within as little as two weeks, suggesting that for some, the benefits may be relatively quick to manifest. For instance, one user noted a remarkable decrease in facial inflammation and acne within this period Read Review. Other users, however, have mentioned that it took a bit longer, with several indicating that significant improvements appeared around the one to three-month mark. For example, one reviewer experienced softer skin and cleared chin acne after three months of consistent intake Read Review.
It’s important to note, though, that individual responses to Omega-3 can vary widely. While some users see positive changes, others report adverse reactions, including increased breakouts shortly after starting the supplement Read Review. Therefore, it would be prudent to monitor your skin's response closely and consult with a healthcare provider if you experience any negative effects or if you have concerns regarding its use for acne treatment.
Recent research indicates that omega-3 fatty acids could offer promising support in managing acne. One systematic review found that while omega-3s may help reduce acne severity, some omega-6 fatty acids could exacerbate it [1]. Notably, a study involving participants who incorporated algae-derived omega-3 supplements into their diets for 16 weeks reported a significant improvement in acne severity, especially among those who achieved optimal omega-3 levels [2]. Furthermore, another controlled study highlighted reductions in both inflammatory and non-inflammatory acne lesions among participants using omega-3 supplements [7].
That said, while the benefits of omega-3 fatty acids in acne management are noted, researchers caution against viewing them as a standalone remedy. Instead, they are best considered as a supplement to traditional treatments [5]. Additional studies, such as those examining the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on skin health, support their potential role in improving inflammatory conditions and the overall quality of life for patients. However, more extensive research is needed to understand fully how these fatty acids interact with various factors influencing acne [11].
Based on user reviews, many individuals have reported notable improvements in their skin health after incorporating Omega-3 supplements into their routine. For example, one user mentioned a significant reduction in acne, with marked improvements in the overall quality of their skin Read Review. Similarly, another reviewer stated that both their and their child's persistent acne cleared completely after a month of use, indicating a strong response to the supplement Read Review. Other testimonials highlight benefits such as fading acne scars and improved skin texture, with one user noting a glossier appearance after consistent use Read Review.
However, it’s crucial to recognize that individual experiences can vary significantly. While some users have enjoyed clear skin and reduced inflammation, others have reported negative reactions, including increased acne outbreaks or discomfort Read Review. Certain reviewers even observed a quick return to their prior issues after discontinuing the supplement, underscoring the importance of monitoring your body's reaction to Omega-3 and consulting a healthcare provider if adverse effects occur Read Review. Ultimately, while many find Omega-3 beneficial for skin health, its efficacy seems to be highly individualized.
Based on user reviews, the experiences surrounding the combination of Omega-3 with other supplements for managing acne seem to vary widely. Some users specifically recommend combining Omega-3 with vitamin D, asserting that this combination enhances the skin benefits and effectiveness against acne Read Review. These individuals suggest that consistent intake of both supplements is crucial for maximizing results.
Conversely, numerous reviews also highlight negative experiences when using Omega-3, with some users reporting that it can exacerbate acne rather than alleviate it. For instance, several users noted increased breakouts or worsening skin conditions after starting Omega-3, which often led to discontinuation of the supplement Read Review, Read Review. These mixed outcomes suggest that while Omega-3 may be effective for some, its impact can be unpredictable, especially when combined with other supplements. Therefore, it's advisable to approach any supplement regimen cautiously and monitor individual responses closely.
The optimal dose for Omega-3 Fish Oil, particularly focusing on eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), for treating acne appears to be around 2,000 mg per day, based on a controlled study that yielded significant improvements in acne severity. In this study involving 45 participants, those taking 2,000 mg of EPA along with DHA experienced notable reductions in both inflammatory and non-inflammatory acne lesions over a period of ten weeks [7]. This aligns with other research suggesting that increasing Omega-3 levels can be beneficial, particularly for individuals who may have a deficiency [2].
It's crucial to consider that while Omega-3 supplementation may be effective for some, individual responses can vary. A study noted that while many participants saw improvement, a few reported worsening conditions [8]. Thus, incorporating Omega-3, especially through a combination of dietary adjustments and supplementation, may enhance overall skin health and support acne management, but should be viewed as a complement to traditional treatments rather than a standalone solution [5].
9
Decreased inflammation
1 people found this helpful
This Omega-3 has worked wonders for my hormonal acne. Within two weeks, I noticed a significant decrease in facial inflammation that I’d dealt with for years. I am extremely pleased and hope this improvement continues.
9
Softer skin
1 people found this helpful
After three months of taking this, my skin has become softer, and my chin acne disappeared. When I stopped taking it, my skin stiffened, confirming its beneficial impact on reducing acne. I intend to continue taking it.
0
Caused acne
I had high hopes for this omega-3, but unfortunately, it causes my acne to flare up noticeably even with just one pill a day. After stopping, my skin clears up, but the acne returns when I resume taking it. I warn you about this possible reaction.
7.5
Reduced acne
150 people found this helpful
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
9
Lasting results
100 people found this helpful
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
9
Less acne scars
80 people found this helpful
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
0
Worsened acne
5 people found this helpful
I ordered this Omega based on good reviews, but it worsened my skin condition with subcutaneous acne. Discontinuing the product improved my skin, and I experienced severe stomach pain as well. I do not recommend it.
9
Skin benefits
12 people found this helpful
I highly recommend omega-3 for its numerous skin benefits, especially for acne sufferers. Combining it with vitamin D maximises the effects. It’s essential to take it consistently for the best results.
0
Acne problem
I bought omega for its benefits, but it causes acne under my chin. I'm puzzled as to why this happens.
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
9
Omega-3 improves acne severity
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
8
Omega-3 improves acne symptoms
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
7
Omega-3s benefit inflammatory skin conditions
The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review.
We examined a variety of studies on omega-3 fatty acids (O3FAs) and their impact on skin conditions, including acne. The review encompassed 38 studies, highlighting benefits such as a reduction in inflammatory lesions and side effects from other acne treatments like isotretinoin.
Although the findings suggest potential advantages, specifically for inflammatory skin issues, O3FAs are best viewed as a supplemental option rather than a standalone solution for acne. Overall, their low cost and safety make them a viable addition to treatment strategies for those seeking to improve their skin health.
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
4
Fish oil may improve acne severity
Effects of fish oil supplementation on inflammatory acne.
We evaluated the effects of omega-3 fish oil on inflammatory acne in a group of 13 individuals over 12 weeks. Each participant continued their regular acne treatments while taking three grams of fish oil daily.
While the overall results showed no significant changes in acne severity scores or inflammatory lesion counts, we observed varied individual responses. Eight participants showed improvement, particularly those with moderate to severe acne, while four experienced worsening conditions.
These findings suggest that omega-3 supplementation may be beneficial for some, but further research is necessary to confirm its effectiveness.
References
Zhang L, Li Y, Pu Y, Dang T, Shi Q, et al. Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne. Eur J Nutr. 2025;64:130. 10.1007/s00394-025-03647-4
Guertler A, Neu K, Lill D, Clanner-Engelshofen B, French LE, et al. Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study. J Cosmet Dermatol. 2024;23:3295. 10.1111/jocd.16434
Huang Y, Liu F, Lai J, Jiang S, Tan X, et al. The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris. J Dermatolog Treat. 2024;35:2299107. 10.1080/09546634.2023.2299107
Zainab Z, Malik NA, Obaid S, Malik S, Aftab K, et al. Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris. J Ayub Med Coll Abbottabad. 2021;33:60.
Thomsen BJ, Chow EY, Sapijaszko MJ. The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review. J Cutan Med Surg. 2020;24:481. 10.1177/1203475420929925
Aslan İ, Özcan F, Karaarslan T, Kıraç E, Aslan M. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. Prostaglandins Other Lipid Mediat. 2017;128-129:1. 10.1016/j.prostaglandins.2016.12.001
Jung JY, Kwon HH, Hong JS, Yoon JY, Park MS, et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. Acta Derm Venereol. 2014;94:521. 10.2340/00015555-1802
Khayef G, Young J, Burns-Whitmore B, Spalding T. Effects of fish oil supplementation on inflammatory acne. Lipids Health Dis. 2012;11:165. 10.1186/1476-511X-11-165
Desbois AP, Lawlor KC. Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus. Mar Drugs. 2013;11:4544. 10.3390/md11114544
Rubin MG, Kim K, Logan AC. Acne vulgaris, mental health and omega-3 fatty acids: a report of cases. Lipids Health Dis. 2008;7:36. 10.1186/1476-511X-7-36
Kim BR, Kim G, Jin SP, Choi CW, Kim J, et al. The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study. Br J Dermatol. 2025. 10.1093/bjd/ljaf052