Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.2
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*
Top Medical Research Studies
9
We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.
Read More
7
We investigated the impact of two probiotic strains, Lactobacillus rhamnosus BFE5264 and Lactiplantibacillus plantarum NR74, on high cholesterol levels in a murine model. The results indicated that these probiotics help reduce cholesterol absorption in the intestines and support liver metabolism.
Specifically, L. rhamnosus was particularly effective in boosting cholesterol processing in the liver. However, as this study focused on animal models, more research is needed to confirm these findings in humans.
Overall, these probiotics show promise for managing diet-related hypercholesterolemia.
Specifically, L. rhamnosus was particularly effective in boosting cholesterol processing in the liver. However, as this study focused on animal models, more research is needed to confirm these findings in humans.
Overall, these probiotics show promise for managing diet-related hypercholesterolemia.
Read More
9
Lactobacillus rhamnosus shows cholesterol-lowering effects
We examined the potential of Lactobacillus rhamnosus and other strains to lower cholesterol levels. Through in vitro testing, we observed impressive cholesterol reduction rates, achieving up to 91% decrease after 120 hours. When we moved to in vivo studies using rats fed fermented milk, we noted reductions in overall cholesterol, LDL, and triglycerides, while also enhancing HDL levels. Importantly, these probiotic strains demonstrated safety and effectiveness in their role as natural options for managing high cholesterol.
Read More
Most Useful Reviews
8
Improves gut health
1 people found this helpful
I loved this supplement and will undoubtedly buy it again. I noticed an improvement in my gut health and digestion—these strains are excellent for the microbiome. It has no taste, and the package size of 30 pills is convenient. Great quality. Highly recommended for anyone wanting to enhance their gut health.
Read More
2
Dissatisfied with product
12 people found this helpful
I had no effect at all. I have used various intestinal preparations since childhood for my weak gastrointestinal tract, particularly intestines. I was fond of Healthy Origins probiotics, but switching to this product worsened my abdominal bloating and constipation. The content should be high, and while the ingredients are similar, they differ significantly. I’ve since purchased Healthy Origins elsewhere and find the variety decreased since I-Herb became a Korean company, which has frustrated me.
Read More
7
Lowers cholesterol
1 people found this helpful
PROBIOTICS! Excellent for boosting the immune system, balancing good bacteria, lowering cholesterol, fighting allergies, and improving digestion. It may even enhance mental health.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.2
- All Researches
9
We investigated the effects of Lactobacillus rhamnosus on high cholesterol and blood sugar levels in diabetic rats.
By using yogurt fermented with this probiotic, we noticed significant reductions in blood glucose and an increase in healthy cholesterol levels.
Within just four days of consuming the yogurt, notable changes in liver and kidney enzymes were observed, alongside improvements in lipid profiles.
While promising, further research is needed to confirm these benefits in humans.
By using yogurt fermented with this probiotic, we noticed significant reductions in blood glucose and an increase in healthy cholesterol levels.
Within just four days of consuming the yogurt, notable changes in liver and kidney enzymes were observed, alongside improvements in lipid profiles.
While promising, further research is needed to confirm these benefits in humans.
Read More
9
We investigated the cholesterol-lowering effects of two specific probiotic strains, FM9 and Y57, using a high-fat diet model in male Wistar rats. Over 30 days, these strains demonstrated a significant ability to improve blood lipid profiles.
Notably, FM9 and Y57 reduced serum cholesterol levels by 9% and 8%, respectively, while also improving "good" HDL cholesterol levels more than the statin treatment.
These results suggest that probiotics like FM9 and Y57 may offer a natural alternative to conventional medications for managing cholesterol, with the potential for anti-obesity benefits too, though clinical trials are needed to confirm these effects in humans.
Notably, FM9 and Y57 reduced serum cholesterol levels by 9% and 8%, respectively, while also improving "good" HDL cholesterol levels more than the statin treatment.
These results suggest that probiotics like FM9 and Y57 may offer a natural alternative to conventional medications for managing cholesterol, with the potential for anti-obesity benefits too, though clinical trials are needed to confirm these effects in humans.
Read More
9
We explored how two specific probiotic strains, Lactobacillus johnsonni 3121 and Lactobacillus rhamnosus 86, impact high cholesterol conditions linked to obesity. In our study using obese mice on a high-fat diet, we observed that daily doses of these probiotics over 12 weeks led to significant improvements in cholesterol levels.
Notably, both strains reduced lipid accumulation and influenced the genes involved in fat cell development. Additionally, they helped restore the balance of gut bacteria affected by obesity. These findings suggest that these probiotics could be valuable in managing high cholesterol and obesity-related health issues.
Notably, both strains reduced lipid accumulation and influenced the genes involved in fat cell development. Additionally, they helped restore the balance of gut bacteria affected by obesity. These findings suggest that these probiotics could be valuable in managing high cholesterol and obesity-related health issues.
Read More
9
Lactobacillus rhamnosus shows cholesterol-lowering effects
We examined the potential of Lactobacillus rhamnosus and other strains to lower cholesterol levels. Through in vitro testing, we observed impressive cholesterol reduction rates, achieving up to 91% decrease after 120 hours. When we moved to in vivo studies using rats fed fermented milk, we noted reductions in overall cholesterol, LDL, and triglycerides, while also enhancing HDL levels. Importantly, these probiotic strains demonstrated safety and effectiveness in their role as natural options for managing high cholesterol.
Read More
9
We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
8
Improves gut health
1 people found this helpful
I loved this supplement and will undoubtedly buy it again. I noticed an improvement in my gut health and digestion—these strains are excellent for the microbiome. It has no taste, and the package size of 30 pills is convenient. Great quality. Highly recommended for anyone wanting to enhance their gut health.
Read More
2
Dissatisfied with product
12 people found this helpful
I had no effect at all. I have used various intestinal preparations since childhood for my weak gastrointestinal tract, particularly intestines. I was fond of Healthy Origins probiotics, but switching to this product worsened my abdominal bloating and constipation. The content should be high, and while the ingredients are similar, they differ significantly. I’ve since purchased Healthy Origins elsewhere and find the variety decreased since I-Herb became a Korean company, which has frustrated me.
Read More
7
Lowers cholesterol
1 people found this helpful
PROBIOTICS! Excellent for boosting the immune system, balancing good bacteria, lowering cholesterol, fighting allergies, and improving digestion. It may even enhance mental health.
Read More
Frequently Asked Questions
7
Lowers cholesterol
1 people found this helpful
PROBIOTICS! Excellent for boosting the immune system, balancing good bacteria, lowering cholesterol, fighting allergies, and improving digestion. It may even enhance mental health.
2
Dissatisfied with product
12 people found this helpful
I had no effect at all. I have used various intestinal preparations since childhood for my weak gastrointestinal tract, particularly intestines. I was fond of Healthy Origins probiotics, but switching to this product worsened my abdominal bloating and constipation. The content should be high, and while the ingredients are similar, they differ significantly. I’ve since purchased Healthy Origins elsewhere and find the variety decreased since I-Herb became a Korean company, which has frustrated me.
8
Improves gut health
1 people found this helpful
I loved this supplement and will undoubtedly buy it again. I noticed an improvement in my gut health and digestion—these strains are excellent for the microbiome. It has no taste, and the package size of 30 pills is convenient. Great quality. Highly recommended for anyone wanting to enhance their gut health.
9
We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.
7
We explored how a new combination of Lactobacillus rhamnosus and xylo-oligosaccharides could help lower cholesterol levels. The study tested this synbiotic approach by simulating cholesterol-lowering effects in a lab setting.
Results suggested that it may work by down-regulating certain genes involved in cholesterol absorption and promoting a healthier gut microbiome. While promising, further research is needed to confirm its effectiveness in real-world conditions among people.
Results suggested that it may work by down-regulating certain genes involved in cholesterol absorption and promoting a healthier gut microbiome. While promising, further research is needed to confirm its effectiveness in real-world conditions among people.
8
We dove into how lactobacillus rhamnosus, along with other lactic acid bacteria, can help reduce cholesterol levels. Our research showed that these probiotics not only lowered cholesterol in a lab setting but also did so effectively in living organisms.
Specifically, lactobacillus rhamnosus cut cholesterol levels by up to 40%. Importantly, these strains were safe and non-toxic, making them promising candidates for managing high cholesterol. Overall, this study suggests a potential natural approach to tackle hypercholesterolemia.
Specifically, lactobacillus rhamnosus cut cholesterol levels by up to 40%. Importantly, these strains were safe and non-toxic, making them promising candidates for managing high cholesterol. Overall, this study suggests a potential natural approach to tackle hypercholesterolemia.
9
We explored how two specific probiotic strains, Lactobacillus johnsonni 3121 and Lactobacillus rhamnosus 86, impact high cholesterol conditions linked to obesity. In our study using obese mice on a high-fat diet, we observed that daily doses of these probiotics over 12 weeks led to significant improvements in cholesterol levels.
Notably, both strains reduced lipid accumulation and influenced the genes involved in fat cell development. Additionally, they helped restore the balance of gut bacteria affected by obesity. These findings suggest that these probiotics could be valuable in managing high cholesterol and obesity-related health issues.
Notably, both strains reduced lipid accumulation and influenced the genes involved in fat cell development. Additionally, they helped restore the balance of gut bacteria affected by obesity. These findings suggest that these probiotics could be valuable in managing high cholesterol and obesity-related health issues.
References
- Correia Gomes D, Meza Alvarado JE, Zamora Briseño JA, Cano Sarmiento C, Camacho Morales A, et al. Maternal Supplementation with GG Improves Glucose Tolerance and Modulates the Intestinal Microbiota of Offspring. Diseases. 2024;12. doi:10.3390/diseases12120312
- Dang L, Li D, Mu Q, Zhang N, Li C, et al. Youth-derived Lactobacillus rhamnosus with prebiotic xylo-oligosaccharide exhibits anti-hyperlipidemic effects as a novel synbiotic. Food Res Int. 2024;195:114976. doi:10.1016/j.foodres.2024.114976
- Papakonstantinou E, Zacharodimos N, Georgiopoulos G, Athanasaki C, Bothou DL, et al. Two-Month Consumption of Orange Juice Enriched with Vitamin D3 and Probiotics Decreases Body Weight, Insulin Resistance, Blood Lipids, and Arterial Blood Pressure in High-Cardiometabolic-Risk Patients on a Westernized Type Diet: Results from a Randomized Clinical Trial. Nutrients. 2024;16. doi:10.3390/nu16091331
- Negm El-Dein A, Ezzat A, Aly HF, Awad G, Farid M. Lactobacillus-fermented yogurt exerts hypoglycemic, hypocholesterolemic, and anti-inflammatory activities in STZ-induced diabetic Wistar rats. Nutr Res. 2022;108:22. doi:10.1016/j.nutres.2022.10.003
- Zafar H, Ain NU, Alshammari A, Alghamdi S, Raja H, et al. FM9 and Y57 Are as Effective as Statins at Improving Blood Lipid Profile in High Cholesterol, High-Fat Diet Model in Male Wistar Rats. Nutrients. 2022;14. doi:10.3390/nu14081654
- Yoon H, Lee Y, Kang HJ, Ju J, Ji Y, et al. Two putative probiotic strains improve diet-induced hypercholesterolemia through modulating intestinal cholesterol uptake and hepatic cholesterol efflux. J Appl Microbiol. 2022;132:562. doi:10.1111/jam.15181
- Daliri EB, Kim Y, Do Y, Chelliah R, Oh DH. In Vitro and In Vivo Cholesterol Reducing Ability and Safety of Probiotic Candidates Isolated from Korean Fermented Soya Beans. Probiotics Antimicrob Proteins. 2022;14:87. doi:10.1007/s12602-021-09798-0
- Lee CS, Park MH, Kim BK, Kim SH. Antiobesity Effect of Novel Probiotic Strains in a Mouse Model of High-Fat Diet-Induced Obesity. Probiotics Antimicrob Proteins. 2021;13:1054. doi:10.1007/s12602-021-09752-0
- El-Dein AN, Nour El-Deen AM, El-Shatoury EH, Awad GA, Ibrahim MK, et al. Assessment of exopolysaccharides, bacteriocins and in vitro and in vivo hypocholesterolemic potential of some Egyptian Lactobacillus spp. Int J Biol Macromol. 2021;173:66. doi:10.1016/j.ijbiomac.2021.01.107
- Das S, Mishra BK, Hati S. Techno-functional characterization of indigenous isolates from the traditional fermented foods of Meghalaya, India. Curr Res Food Sci. 2020;3:9. doi:10.1016/j.crfs.2020.01.002
- Romão da Silva LF, de Oliveira Y, de Souza EL, de Luna Freire MO, Braga VA, et al. Effects of probiotic therapy on cardio-metabolic parameters and autonomic modulation in hypertensive women: a randomized, triple-blind, placebo-controlled trial. Food Funct. 2020;11:7152. doi:10.1039/d0fo01661f
- Wa Y, Yin B, He Y, Xi W, Huang Y, et al. Effects of Single Probiotic- and Combined Probiotic-Fermented Milk on Lipid Metabolism in Hyperlipidemic Rats. Front Microbiol. 2019;10:1312. doi:10.3389/fmicb.2019.01312
- Yan Y, Zhang F, Chai Z, Liu M, Battino M, et al. Mixed fermentation of blueberry pomace with L. rhamnosus GG and L. plantarum-1: Enhance the active ingredient, antioxidant activity and health-promoting benefits. Food Chem Toxicol. 2019;131:110541. doi:10.1016/j.fct.2019.05.049
- Park S, Kang J, Choi S, Park H, Hwang E, et al. Cholesterol-lowering effect of Lactobacillus rhamnosus BFE5264 and its influence on the gut microbiome and propionate level in a murine model. PLoS One. 2018;13:e0203150. doi:10.1371/journal.pone.0203150
- Oh NS, Joung JY, Lee JY, Kim Y. Probiotic and anti-inflammatory potential of Lactobacillus rhamnosus 4B15 and Lactobacillus gasseri 4M13 isolated from infant feces. PLoS One. 2018;13:e0192021. doi:10.1371/journal.pone.0192021
- Roselli M, Devirgiliis C, Zinno P, Guantario B, Finamore A, et al. Impact of supplementation with a food-derived microbial community on obesity-associated inflammation and gut microbiota composition. Genes Nutr. 2017;12:25. doi:10.1186/s12263-017-0583-1
