NOW Supplements Vitamin E

We explored the potential role of vitamin E in treating leg cramps, particularly in populations such as those undergoing dialysis. The study aimed to understand if vitamin E could provide relief from troublesome nocturnal leg cramps—an issue that many individuals face.

While the effects of quinine, a common treatment, have been closely scrutinized, vitamin E emerges as a noteworthy alternative. Although large-scale randomized controlled trials focusing specifically on vitamin E for leg cramps are limited, some data suggest that it may hold promise for alleviating symptoms. This is especially true for those who might not respond to other treatments.

We observed that incorporating vitamin E could be a safer option, as this supplement generally has a more favorable safety profile compared to quinine. However, it's important to underscore that patients should consider exploring other treatments before turning to quinine, particularly given the latter's potential side effects.

9.5

Cramps disappeared

Most Useful Review

I have suffered from severe leg cramps, and after being advised to take this supplement for about 3 months, I noticed a reduction in pain. By the second month, the pain had entirely vanished! Previously, it was so intense that I struggled to walk, but now I can manage comfortably without issues. I will continue to take it.

Allergies details

Vitamin E in allergy treatment explored

Reductive Adjuvant Nanosystem for Alleviated Atopic Dermatitis Syndromes.

Most Relevant Research

We explored the potential of a specially designed nanoemulsion containing vitamin E to address the symptoms of atopic dermatitis (AD), a chronic skin condition that significantly impacts quality of life. In this study, the formulation, named PV-NE, aimed to balance the immune system and reduce inflammation characterized by the overproduction of reactive oxygen species (ROS), which are linked to worsening allergic reactions.

Through our research, we noted that while PV-NE demonstrated effectiveness in restoring immune balance and alleviating symptoms like itching and skin irritation, it did not isolate the effects of vitamin E specifically on allergies. Instead, the focus was on how the combination worked as a whole. This means that while vitamin E plays a role in the treatment via the nanoemulsion, we can't conclusively say it effectively treats allergies when considered on its own.

Ultimately, our findings establish a foundation for further exploration of vitamin E's contributions within broader therapeutic systems, indicating its biocompatibility and importance in future treatments for AD and potentially other allergies.

9.5

No allergic reactions

Most Useful Review

I find E-400 vitamins beneficial for improving memory. They are easy to take, and I haven’t experienced any stomach discomfort. Having taken E-400 for over two years, I haven't had any allergies related to this vitamin.

The role of α-tocopherol in the prevention and treatment of Alzheimer's disease.

Most Relevant Research

We sought to understand the potential role of α-tocopherol, a form of vitamin E, in preventing and treating Alzheimer's disease. Various research studies have indicated that this antioxidant might slow down the disease's progression or even reduce the risk of developing dementia. Our review delved into the biochemical mechanisms of α-tocopherol, highlighting its anti-inflammatory properties and ability to combat oxidative stress, which are vital in Alzheimer's pathology.

Interestingly, higher intake of α-tocopherol is linked to a lower incidence of mild cognitive impairment, suggesting its protective effects. However, we also noted that many people do not consume sufficient amounts of this vital nutrient. While there's a promising outlook for α-tocopherol supplementation as part of Alzheimer's management, we acknowledge that further research is necessary to draw definitive conclusions regarding its effectiveness and the mechanism behind its action.

Overall, our exploration into the relationship between vitamin E and Alzheimer's sheds light on a possible avenue for intervention, though clarity in treatment specifics and comprehensive studies are still required.

9.5

Alzheimer's dementia slowdown

Most Useful Review

Vitamin E perfectly improves hair and skin conditions while promoting the regeneration of damaged areas. It slows down dementia processes in Alzheimer's disease and other neurodegenerative disorders and is utilised in the prevention and treatment of cancerous diseases.

Cancer details

SCIENTIFIC SCORE

Moderately Effective

Based on 9 Researches

Gamma-tocopherol in cancer research

Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.

Most Relevant Research

We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.

In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.

Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.

While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.

9.5

Supports cancer prevention

Most Useful Review

Vitamin E is a fat-soluble vitamin known for its antioxidant and radioprotective properties. It aids in the synthesis of heme and proteins, cell proliferation, and cellular metabolism. It enhances tissue oxygen consumption, supports heart function, and contributes to red blood cell formation. Vitamin E boosts the immune system, combats oxidative stress, and plays a preventive role against cancer. Overall, it is of good quality, well-packaged, and contributes to a calm nervous system as well as fast metabolism.

Cold Sores details

Alleviated cold symptoms

Most Useful Review

I started taking Vitamin E to improve blood flow. Initially, I increased my dosage too quickly, which I later realised was not advisable. However, my cold extremities disappeared, and I no longer have cold hands and feet, even in winter. Stopping the supplement brought back my tinnitus, but taking it again made me feel better.

Common Cold details

My blood circulation has long been poor, causing my toes to feel extremely cold in winter, even in a warm room. Since taking megavitamin, that issue has improved. I also realised a lack of vitamin E leads to redness and itchiness in my toes during winter. Thank you for this successful product!

Diabetes details

Enhances diabetes treatment

Most Useful Review

I take vitamin E from Now Foods for type 2 diabetes. It has good quality, and the capsule size is easy to swallow. The 400-unit tocopherol dose positively affects my hair and alleviates skin dryness. As an effective antioxidant for heart diseases and diabetes, I don't notice any taste and appreciate the packaging, which features d-alpha tocopherol.

Eczema details

Vitamin E may aid eczema relief

Biochemical and Clinical Effects of Vitamin E Supplementation in Hungarian Smith-Lemli-Opitz Syndrome Patients.

Most Relevant Research

We explored the effects of vitamin E supplementation on patients with Smith-Lemli-Opitz Syndrome (SLOS), particularly focusing on symptoms like eczema. In a three-year study, six patients who were already on dietary cholesterol treatment received vitamin E. Their vitamin E levels were initially low, but following supplementation, all patients showed a significant increase in plasma vitamin E concentrations.

Among the various symptoms assessed, including aggression, irritability, and skin issues like eczema, some patients reported improvements. Our findings indicated that three out of the six patients experienced a reduction in symptoms, including skin photosensitivity and eczema. Notably, those who responded best to therapy had lower baseline ratios of certain cholesterol-related compounds.

While the study suggests that vitamin E could provide benefits to SLOS patients—possibly contributing to improvements in skin conditions like eczema—individual responses varied. Thus, vitamin E supplementation may be worth considering in the management of SLOS, especially for those with low initial vitamin E levels and certain biochemical markers.

9.5

Eczema relief

Most Useful Review

I gave this to my mother suffering from eczema. It took about three weeks, but her eczema became significantly better. It was already severe, likely due to dry conditions. I didn't need any additional medication after she took two tablets of Vitamin E, which is a relief for us.

Heart Attack details

Heart attack prevention

Most Useful Review

Vitamin E is vital! Taking 400 IU daily significantly protects against sudden heart attacks and improves blood circulation without toxicity. It aids in protein synthesis and helps cleanse the blood of harmful fats. I ensure to take it with fats for optimal absorption, which has helped prevent wrinkles and support my overall health.

High Cholesterol details

Strong antioxidant benefits

Most Useful Review

I find Vitamin E to be a vital antioxidant that protects against heart attacks and cleanses the blood, improving circulation without toxicity, unlike some anticoagulant drugs. I take it with omega acids for better absorption, especially helpful for my high cholesterol condition.

Insomnia details

Improves sleep quality

Most Useful Review

Antioxidant has a stabilising effect in cases of insomnia, depression, autonomic disorders, and other conditions, such as during menopause or in old age. The ingredients are natural, assisting in relieving excess stress, stimulating brain function, improving concentration, increasing performance, and normalising sleep and mood. The capsules are of medium size. GABA, a neurotransmitter of the central nervous system, enhances sleep quality, facilitating the release of growth hormone at night. This component mitigates stress effects and provides deeper and more effective sleep. The dosage is optimal.

Liver Disease details

Don't be misled by other tocopherol forms; we need alpha-tocopherol. This product offers the alpha form, which is what the body absorbs. Other tocopherols get destroyed in the liver. Alpha-tocopherol has a specific protein to aid absorption, so avoid overloading your liver with forms that cannot be absorbed easily.

Prostate Cancer details

Gamma-tocopherol and prostate cancer

Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.

Most Relevant Research

We dove into the fascinating realm of gamma-tocopherol, a key form of vitamin E, to understand its impact on prostate cancer treatment. Research indicates that gamma-tocopherol possesses strong antioxidant and anti-inflammatory properties, which could potentially translate into benefits for those facing prostate cancer.

Specifically, we observed that gamma-tocopherol neutralizes harmful reactive oxygen and nitrogen species in the body. This action not only protects cells from oxidative damage but also helps reduce chronic inflammation, a factor often linked to cancer progression.

What truly caught our attention was gamma-tocopherol's multifaceted role in cancer therapy. Evidence suggests that it may inhibit tumor growth, induce apoptosis (the process of programmed cell death), and even suppress the formation of new blood vessels that tumors require to grow. This makes it particularly interesting for managing prostate cancer, alongside its impact on other cancers.

Despite this promising profile, we find that high doses of gamma-tocopherol require careful consideration to avoid potential adverse effects. Overall, while gamma-tocopherol shows potential in understanding and managing prostate cancer, further research is necessary to fully grasp its effectiveness in clinical settings.

8.8

Antioxidant benefits

Most Useful Review

Prostate cancer treatment benefits all men, regardless of age. For better absorption, I find it more effective when taken after meals and separately from magnesium and vitamin D3. Women also benefit as it serves as an antioxidant for youth and beauty.

SCIENTIFIC SCORE

Moderately Effective

Based on 3 Researches

Vitamin E enhances vaginal health

Retrospective Investigator-Initiated Trial on Tocopherol Acetate Vaginal Administration in Pre-and Postmenopausal Women.

Most Relevant Research

We examined how tocopherol acetate, commonly known as vitamin E, affects vaginal health in women experiencing menopause and those who are premenopausal. The study involved 50 women, split into two groups: 28 postmenopausal and 22 premenopausal, who were assessed before and after a two-week treatment with tocopherol acetate ovules.

After the treatment period, we observed significant improvements in the bothersome symptoms associated with vaginal atrophy, such as dryness, itching, and discomfort during intercourse. Participants reported a noticeable difference in their vaginal health post-treatment, which is quite encouraging. Additionally, a molecular analysis indicated a positive change in the vaginal microbiota, particularly among the premenopausal group, suggesting that vitamin E can help foster a healthier vaginal environment.

Overall, our findings support the potential benefits of using tocopherol acetate for enhancing vaginal well-being during menopause. This could offer a natural alternative for women seeking relief from menopausal symptoms, improving their quality of life during this transitional phase.

9.5

Cyst reduction

Most Useful Review

Vitamin E has rejuvenating properties. During menopause, I took it consistently and managed to eliminate two ovarian cysts with this product.