Last update
3/18/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 4 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
9
We explored the potential of combining vitamin E, an antioxidant known as α-tocopherol, with oseltamivir, a neuraminidase inhibitor, to treat influenza in a mouse model.
The study found that administering both substances together resulted in a significant decrease in mortality rates, particularly when given simultaneously after infection.
However, earlier administration of vitamin E did not show the same effectiveness. Overall, while vitamin E may enhance the antiviral effects of oseltamivir, its timing is crucial for achieving the best outcomes.
The study found that administering both substances together resulted in a significant decrease in mortality rates, particularly when given simultaneously after infection.
However, earlier administration of vitamin E did not show the same effectiveness. Overall, while vitamin E may enhance the antiviral effects of oseltamivir, its timing is crucial for achieving the best outcomes.
Read More
Most Useful Reviews
7.5
Boosted immune system
1 people found this helpful
Having taken NOW Foods E-400 for over a year, I can say it has positively impacted my health. Its antioxidant properties seem to have enhanced my skin texture and supported my immune system, especially during flu season. The capsules are easy to swallow and fit seamlessly into my daily routine. I appreciate that they are non-GMO and vegetarian. I highly recommend this to anyone wanting to increase their vitamin E intake naturally.
Read More
7.5
Supports treatment
While undergoing infertility treatment, I take one capsule after dinner. The capsule is transparent, though firmer than Omega. It seems to help thicken my endometrium, which I hope will aid in conceiving. I also take iron in the morning, ensuring I take it at least eight hours later.
Read More
7.5
Aided chilblains
My mother had chilblains and noticed improvement after taking it. I experienced mild chilblains too, and I'm feeling better after using this. The soft capsules are easy to consume, and I appreciate their antioxidant properties, so I will continue taking them for my skin health.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We explored the potential of combining vitamin E, an antioxidant known as α-tocopherol, with oseltamivir, a neuraminidase inhibitor, to treat influenza in a mouse model.
The study found that administering both substances together resulted in a significant decrease in mortality rates, particularly when given simultaneously after infection.
However, earlier administration of vitamin E did not show the same effectiveness. Overall, while vitamin E may enhance the antiviral effects of oseltamivir, its timing is crucial for achieving the best outcomes.
The study found that administering both substances together resulted in a significant decrease in mortality rates, particularly when given simultaneously after infection.
However, earlier administration of vitamin E did not show the same effectiveness. Overall, while vitamin E may enhance the antiviral effects of oseltamivir, its timing is crucial for achieving the best outcomes.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Boosted immune system
1 people found this helpful
Having taken NOW Foods E-400 for over a year, I can say it has positively impacted my health. Its antioxidant properties seem to have enhanced my skin texture and supported my immune system, especially during flu season. The capsules are easy to swallow and fit seamlessly into my daily routine. I appreciate that they are non-GMO and vegetarian. I highly recommend this to anyone wanting to increase their vitamin E intake naturally.
Read More
7.5
Supports treatment
While undergoing infertility treatment, I take one capsule after dinner. The capsule is transparent, though firmer than Omega. It seems to help thicken my endometrium, which I hope will aid in conceiving. I also take iron in the morning, ensuring I take it at least eight hours later.
Read More
7.5
Aided chilblains
My mother had chilblains and noticed improvement after taking it. I experienced mild chilblains too, and I'm feeling better after using this. The soft capsules are easy to consume, and I appreciate their antioxidant properties, so I will continue taking them for my skin health.
Read More
6
Prevented flu
E-400 is one of my regular dietary supplements. It helps prevent colds or flu, especially during allergy season.
Read More
Frequently Asked Questions
6
Prevented flu
E-400 is one of my regular dietary supplements. It helps prevent colds or flu, especially during allergy season.
7.5
Boosted immune system
1 people found this helpful
Having taken NOW Foods E-400 for over a year, I can say it has positively impacted my health. Its antioxidant properties seem to have enhanced my skin texture and supported my immune system, especially during flu season. The capsules are easy to swallow and fit seamlessly into my daily routine. I appreciate that they are non-GMO and vegetarian. I highly recommend this to anyone wanting to increase their vitamin E intake naturally.
7.5
Aided chilblains
My mother had chilblains and noticed improvement after taking it. I experienced mild chilblains too, and I'm feeling better after using this. The soft capsules are easy to consume, and I appreciate their antioxidant properties, so I will continue taking them for my skin health.
7.5
Supports treatment
While undergoing infertility treatment, I take one capsule after dinner. The capsule is transparent, though firmer than Omega. It seems to help thicken my endometrium, which I hope will aid in conceiving. I also take iron in the morning, ensuring I take it at least eight hours later.
References
- Galabov AS, Mileva M, Simeonova L, Gegova G. Combination activity of neuraminidase inhibitor oseltamivir and α-tocopherol in influenza virus A (H3N2) infection in mice. Antivir Chem Chemother. 2015;24:83. 10.1177/2040206616656263
Data last updated:
