Last update
5/26/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 11 Reviews
6.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
Top Medical Research Studies
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
Most Useful Reviews
0
Caused severe heartburn
4 people found this helpful
Unfortunately, this product caused severe heartburn for me, which I had never experienced before. Despite several attempts to take it, the result was always the same. My mother, however, had no issues with it.
Read More
9
Heartburn-free vitamin
1 people found this helpful
I added this vitamin to my diet to bolster my immunity. I have not experienced any heartburn or runny nose while taking it. I'm satisfied with the product and will continue using it.
Read More
9
Effective alternative
1 people found this helpful
I opted for this vitamin C to save on costs compared to Solgar, which is twice the price. I anticipated heartburn, but thankfully, I didn't experience it! The product is excellent and effective; we barely bought oranges last winter as I didn’t want to rely on fruits lacking in vitamins. At the first sign of illness, I take 500 mg three times a day. Typically, by morning, I'm symptom-free. I will order it again multiple times.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 11 Reviews
6.5
- All Reviews
- Positive Reviews
- Negative Reviews
0
Caused severe heartburn
4 people found this helpful
Unfortunately, this product caused severe heartburn for me, which I had never experienced before. Despite several attempts to take it, the result was always the same. My mother, however, had no issues with it.
Read More
9
Heartburn-free vitamin
1 people found this helpful
I added this vitamin to my diet to bolster my immunity. I have not experienced any heartburn or runny nose while taking it. I'm satisfied with the product and will continue using it.
Read More
9
Effective alternative
1 people found this helpful
I opted for this vitamin C to save on costs compared to Solgar, which is twice the price. I anticipated heartburn, but thankfully, I didn't experience it! The product is excellent and effective; we barely bought oranges last winter as I didn’t want to rely on fruits lacking in vitamins. At the first sign of illness, I take 500 mg three times a day. Typically, by morning, I'm symptom-free. I will order it again multiple times.
Read More
0
Causes heartburn
1 people found this helpful
Although the composition seemed good and the reviews were positive, it caused me belching and heartburn.
Read More
9
Heartburn-free experience
This vitamin C is effective, and unlike other medications, it did not cause me heartburn at all, which I appreciated.
Read More
Frequently Asked Questions
9
Effective alternative
1 people found this helpful
I opted for this vitamin C to save on costs compared to Solgar, which is twice the price. I anticipated heartburn, but thankfully, I didn't experience it! The product is excellent and effective; we barely bought oranges last winter as I didn’t want to rely on fruits lacking in vitamins. At the first sign of illness, I take 500 mg three times a day. Typically, by morning, I'm symptom-free. I will order it again multiple times.
0
Caused severe heartburn
4 people found this helpful
Unfortunately, this product caused severe heartburn for me, which I had never experienced before. Despite several attempts to take it, the result was always the same. My mother, however, had no issues with it.
4
Occasional heartburn
1 people found this helpful
After taking it, I sometimes experienced heartburn, likely due to increased acidity. I didn't have this issue with Ester-S.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
References
- Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
