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SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
Top Medical Research Studies
7
Vitamin C may lower hypothyroidism risk
Association between total vitamin C intake and hypothyroidism among Hashimoto thyroiditis: National Health and Nutrition Examination Survey, 2007-2012.
Directly addresses the research question
We set out to examine how total vitamin C intake might influence hypothyroidism in individuals with Hashimoto thyroiditis, using data from the National Health and Nutrition Examination Survey conducted between 2007 and 2012. Our study utilized multivariate logistic regression and restricted cubic spline analyses to uncover possible associations.
What we found was quite intriguing. There was a clear negative linear relationship between total vitamin C intake and hypothyroidism. Specifically, participants who consumed higher amounts of vitamin C had a significantly lower likelihood of developing hypothyroidism. Those in the top quartile of vitamin C intake were about 60% less likely to have hypothyroidism compared to those in the lowest quartile.
This pattern remained consistent across different age groups and sexes, further emphasizing the potential benefits of vitamin C for individuals with Hashimoto's. Our findings suggest that increasing vitamin C intake may be a simple and effective strategy for reducing the risk of hypothyroidism in those affected. The data indicates that consuming between 4.57 and 1258.9 mg/day of vitamin C could be beneficial.
Overall, our research adds to the understanding of how antioxidants like vitamin C can play a role in thyroid health, encouraging us to consider dietary sources of this vital vitamin for those managing Hashimoto's thyroiditis.
What we found was quite intriguing. There was a clear negative linear relationship between total vitamin C intake and hypothyroidism. Specifically, participants who consumed higher amounts of vitamin C had a significantly lower likelihood of developing hypothyroidism. Those in the top quartile of vitamin C intake were about 60% less likely to have hypothyroidism compared to those in the lowest quartile.
This pattern remained consistent across different age groups and sexes, further emphasizing the potential benefits of vitamin C for individuals with Hashimoto's. Our findings suggest that increasing vitamin C intake may be a simple and effective strategy for reducing the risk of hypothyroidism in those affected. The data indicates that consuming between 4.57 and 1258.9 mg/day of vitamin C could be beneficial.
Overall, our research adds to the understanding of how antioxidants like vitamin C can play a role in thyroid health, encouraging us to consider dietary sources of this vital vitamin for those managing Hashimoto's thyroiditis.
Read More
9
Vitamin C aids liver, kidney function
Vitamin C improves liver and renal functions in hypothyroid rats by reducing tissue oxidative injury.
Study benefits visibility of vitamin C
We investigated how vitamin C affects liver and kidney functions, as well as tissue oxidative damage, in rats with hypothyroidism. The research involved pregnant rats that were divided into five groups, with one group receiving a common thyroid-inhibiting drug and others receiving various doses of vitamin C alongside it. This setup allowed us to compare the effects of vitamin C against a control group.
Throughout a lactation period and into the first eight weeks of their young offspring's lives, we closely monitored several health markers, including thyroid hormone levels, protein concentrations, and oxidative stress indicators in the liver and kidneys. Our findings showed that hypothyroid rats had lower levels of crucial proteins, but those treated with vitamin C exhibited notable improvements.
Vitamin C not only raised the levels of important proteins and thyroid hormone but also reduced harmful oxidative markers in both the liver and kidneys. The doses of 100 mg/kg and 500 mg/kg significantly improved kidney function as indicated by lower creatinine levels and enhanced antioxidant enzyme activity. Overall, vitamin C appeared to protect these organs against oxidative damage and improve their function in hypothyroid conditions.
Throughout a lactation period and into the first eight weeks of their young offspring's lives, we closely monitored several health markers, including thyroid hormone levels, protein concentrations, and oxidative stress indicators in the liver and kidneys. Our findings showed that hypothyroid rats had lower levels of crucial proteins, but those treated with vitamin C exhibited notable improvements.
Vitamin C not only raised the levels of important proteins and thyroid hormone but also reduced harmful oxidative markers in both the liver and kidneys. The doses of 100 mg/kg and 500 mg/kg significantly improved kidney function as indicated by lower creatinine levels and enhanced antioxidant enzyme activity. Overall, vitamin C appeared to protect these organs against oxidative damage and improve their function in hypothyroid conditions.
Read More
9
Vitamin C improves thyroid hormone absorption
Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis.
Study directly addresses vitamin C effects
We explored how vitamin C might assist in the absorption of levothyroxine (l-T4) in patients battling hypothyroidism, particularly those also dealing with gastritis. In this study, 31 patients—with an average age of about 48 years—consumed their prescribed dose of l-T4 mixed in water, sometimes supplemented with 500 mg of vitamin C.
After some time, we carefully measured changes in their thyroid hormone levels. The results were quite encouraging: we found that vitamin C appeared to positively influence serum levels of free T4, T3, and TSH, which are key indicators of thyroid function in these patients. This improvement suggests that vitamin C may play a valuable role in managing hypothyroidism, especially for individuals who have additional gastrointestinal health concerns.
Overall, this study highlights a potential avenue for better control of thyroid hormone levels in patients who struggle with conventional treatments due to malabsorption issues. We believe that incorporating vitamin C into treatment plans for these patients could enhance their overall management and quality of life.
After some time, we carefully measured changes in their thyroid hormone levels. The results were quite encouraging: we found that vitamin C appeared to positively influence serum levels of free T4, T3, and TSH, which are key indicators of thyroid function in these patients. This improvement suggests that vitamin C may play a valuable role in managing hypothyroidism, especially for individuals who have additional gastrointestinal health concerns.
Overall, this study highlights a potential avenue for better control of thyroid hormone levels in patients who struggle with conventional treatments due to malabsorption issues. We believe that incorporating vitamin C into treatment plans for these patients could enhance their overall management and quality of life.
Read More
Most Useful Reviews
9.5
Increased energy
Excellent! I really liked the vitamin D from this manufacturer; I feel energised and active from early morning to late evening, and sometimes even at night. The apathy associated with hypothyroidism has vanished! I have a large jar that will last me a long time, and the small gelatin capsules are convenient to take. I highly recommend it! 👍
Read More
9.5
Boosted vitality
I really liked the vitamin D from this manufacturer; I feel a surge of energy and can stay active from morning till late night. The apathy linked to hypothyroidism has disappeared! The large jar lasts a long time, and the small gelatin capsules are easy to take. Highly recommended! 👍
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
9
Vitamin C mitigates autoimmune hypothyroidism
Boldenone undecylenate disrupts the immune system and induces autoimmune clinical hypothyroidism in rats: Vitamin C ameliorative effects.
Complex interaction with BL abuse
We explored the effects of vitamin C (VC) on hypothyroidism triggered by boldenone undecylenate (BL) in a study involving thirty adult male Wistar rats. The rats were divided into five groups, including a control group, a group treated with VC, and others treated with BL alone or with both BL and VC. Over eight weeks, we carefully examined the impacts on immune responses and thyroid function.
Our findings revealed that BL significantly disrupted the immune system and altered thyroid function, leading to conditions resembling hypothyroidism. Specifically, we observed an increase in thyroid-stimulating hormone and thyroid peroxidase antibody levels, while the critical thyroid hormones decreased. BL also changed immune markers, which affected the overall health of the rats.
However, when we administered VC alongside BL, we noted some promising results: VC appeared to correct many of the disruptions caused by BL. Most immune parameters returned to normal, and the structure and function of the thyroid improved. This indicates that VC could play a protective role against the detrimental effects of BL abuse.
While this study highlights the potential benefits of VC, it's important to remember that it was tested in combination with BL, making it hard to pinpoint VC's effects on hypothyroidism alone. Nonetheless, VC shows promise for managing issues related to BL usage.
Our findings revealed that BL significantly disrupted the immune system and altered thyroid function, leading to conditions resembling hypothyroidism. Specifically, we observed an increase in thyroid-stimulating hormone and thyroid peroxidase antibody levels, while the critical thyroid hormones decreased. BL also changed immune markers, which affected the overall health of the rats.
However, when we administered VC alongside BL, we noted some promising results: VC appeared to correct many of the disruptions caused by BL. Most immune parameters returned to normal, and the structure and function of the thyroid improved. This indicates that VC could play a protective role against the detrimental effects of BL abuse.
While this study highlights the potential benefits of VC, it's important to remember that it was tested in combination with BL, making it hard to pinpoint VC's effects on hypothyroidism alone. Nonetheless, VC shows promise for managing issues related to BL usage.
Read More
9
Vitamin C aids liver, kidney function
Vitamin C improves liver and renal functions in hypothyroid rats by reducing tissue oxidative injury.
Study benefits visibility of vitamin C
We investigated how vitamin C affects liver and kidney functions, as well as tissue oxidative damage, in rats with hypothyroidism. The research involved pregnant rats that were divided into five groups, with one group receiving a common thyroid-inhibiting drug and others receiving various doses of vitamin C alongside it. This setup allowed us to compare the effects of vitamin C against a control group.
Throughout a lactation period and into the first eight weeks of their young offspring's lives, we closely monitored several health markers, including thyroid hormone levels, protein concentrations, and oxidative stress indicators in the liver and kidneys. Our findings showed that hypothyroid rats had lower levels of crucial proteins, but those treated with vitamin C exhibited notable improvements.
Vitamin C not only raised the levels of important proteins and thyroid hormone but also reduced harmful oxidative markers in both the liver and kidneys. The doses of 100 mg/kg and 500 mg/kg significantly improved kidney function as indicated by lower creatinine levels and enhanced antioxidant enzyme activity. Overall, vitamin C appeared to protect these organs against oxidative damage and improve their function in hypothyroid conditions.
Throughout a lactation period and into the first eight weeks of their young offspring's lives, we closely monitored several health markers, including thyroid hormone levels, protein concentrations, and oxidative stress indicators in the liver and kidneys. Our findings showed that hypothyroid rats had lower levels of crucial proteins, but those treated with vitamin C exhibited notable improvements.
Vitamin C not only raised the levels of important proteins and thyroid hormone but also reduced harmful oxidative markers in both the liver and kidneys. The doses of 100 mg/kg and 500 mg/kg significantly improved kidney function as indicated by lower creatinine levels and enhanced antioxidant enzyme activity. Overall, vitamin C appeared to protect these organs against oxidative damage and improve their function in hypothyroid conditions.
Read More
9
Vitamin C may protect brain health
Vitamin C prevents hypothyroidism associated neuronal damage in the hippocampus of neonatal and juvenile rats: A stereological study.
Involves PTU complicates effects
We aimed to investigate how vitamin C might help prevent neuronal damage caused by hypothyroidism in the brains of neonatal and juvenile rats. To carry out this study, we divided pregnant rats into four groups. The control group received regular drinking water, while the other groups were treated with varying amounts of propylthiouracil (PTU), a substance that induces hypothyroidism, alone or in combination with vitamin C.
After a treatment period coinciding with the lactation phase, we carefully examined the brains of some male pups. Our findings revealed that puppies given PTU showed a significant increase in dark neurons and apoptotic cells, indicating marked neuronal damage compared to the control group. Additionally, hypothyroidism caused a decrease in the volume of the hippocampus, a critical brain region linked to memory and learning.
Interestingly, we found that giving vitamin C at a dose of 100 mg/kg noticeably reduced the number of dark neurons and apoptotic cells. It also seemed to mitigate the decrease in hippocampal volume caused by hypothyroidism. This suggests that vitamin C may provide protective benefits against the damaging effects of hypothyroidism in developing brains.
After a treatment period coinciding with the lactation phase, we carefully examined the brains of some male pups. Our findings revealed that puppies given PTU showed a significant increase in dark neurons and apoptotic cells, indicating marked neuronal damage compared to the control group. Additionally, hypothyroidism caused a decrease in the volume of the hippocampus, a critical brain region linked to memory and learning.
Interestingly, we found that giving vitamin C at a dose of 100 mg/kg noticeably reduced the number of dark neurons and apoptotic cells. It also seemed to mitigate the decrease in hippocampal volume caused by hypothyroidism. This suggests that vitamin C may provide protective benefits against the damaging effects of hypothyroidism in developing brains.
Read More
9
Vitamin C aids hypothyroid cognition
The effects of vitamin C on hypothyroidism-associated learning and memory impairment in juvenile rats.
Moderate relevance due to complexity
Our study investigated how vitamin C affects learning and memory in juvenile rats with hypothyroidism. Using a detailed experimental design, we had different groups of pregnant rats treated either with propylthiouracil (PTU) to induce hypothyroidism or given various doses of vitamin C in addition to PTU. This allowed us to compare the effects of vitamin C alongside hypothyroidism treatment.
We found that PTU negatively impacted learning and memory, shown by increased time needed to navigate a maze and lowered performance in memory tests. However, when we introduced vitamin C, particularly in doses of 10, 100, and 500 mg/kg, we noted significant improvements. The rats receiving vitamin C showed faster navigation times, better memory test results, and enhanced brain health markers, such as increased levels of antioxidants.
These findings suggest that vitamin C could serve as a protective agent against learning and memory deficits associated with hypothyroidism in young rats. The improvements in both cognitive function and brain biochemistry highlight the potential of vitamin C as a beneficial treatment complementary to conventional methods for addressing the cognitive concerns tied to hypothyroidism.
We found that PTU negatively impacted learning and memory, shown by increased time needed to navigate a maze and lowered performance in memory tests. However, when we introduced vitamin C, particularly in doses of 10, 100, and 500 mg/kg, we noted significant improvements. The rats receiving vitamin C showed faster navigation times, better memory test results, and enhanced brain health markers, such as increased levels of antioxidants.
These findings suggest that vitamin C could serve as a protective agent against learning and memory deficits associated with hypothyroidism in young rats. The improvements in both cognitive function and brain biochemistry highlight the potential of vitamin C as a beneficial treatment complementary to conventional methods for addressing the cognitive concerns tied to hypothyroidism.
Read More
9
Vitamin C improves thyroid hormone absorption
Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis.
Study directly addresses vitamin C effects
We explored how vitamin C might assist in the absorption of levothyroxine (l-T4) in patients battling hypothyroidism, particularly those also dealing with gastritis. In this study, 31 patients—with an average age of about 48 years—consumed their prescribed dose of l-T4 mixed in water, sometimes supplemented with 500 mg of vitamin C.
After some time, we carefully measured changes in their thyroid hormone levels. The results were quite encouraging: we found that vitamin C appeared to positively influence serum levels of free T4, T3, and TSH, which are key indicators of thyroid function in these patients. This improvement suggests that vitamin C may play a valuable role in managing hypothyroidism, especially for individuals who have additional gastrointestinal health concerns.
Overall, this study highlights a potential avenue for better control of thyroid hormone levels in patients who struggle with conventional treatments due to malabsorption issues. We believe that incorporating vitamin C into treatment plans for these patients could enhance their overall management and quality of life.
After some time, we carefully measured changes in their thyroid hormone levels. The results were quite encouraging: we found that vitamin C appeared to positively influence serum levels of free T4, T3, and TSH, which are key indicators of thyroid function in these patients. This improvement suggests that vitamin C may play a valuable role in managing hypothyroidism, especially for individuals who have additional gastrointestinal health concerns.
Overall, this study highlights a potential avenue for better control of thyroid hormone levels in patients who struggle with conventional treatments due to malabsorption issues. We believe that incorporating vitamin C into treatment plans for these patients could enhance their overall management and quality of life.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
9.5
Increased energy
Excellent! I really liked the vitamin D from this manufacturer; I feel energised and active from early morning to late evening, and sometimes even at night. The apathy associated with hypothyroidism has vanished! I have a large jar that will last me a long time, and the small gelatin capsules are convenient to take. I highly recommend it! 👍
Read More
9.5
Boosted vitality
I really liked the vitamin D from this manufacturer; I feel a surge of energy and can stay active from morning till late night. The apathy linked to hypothyroidism has disappeared! The large jar lasts a long time, and the small gelatin capsules are easy to take. Highly recommended! 👍
Read More
