Supplement Facts
Serving Size: 1 tbsp (15 ml)
Amount Per Serving
%DV
Calories
120
Total Fat
14 g
18%
Saturated Fat
2.5 g
13%
Polyunsaturated Fat
8 g
Monounsaturated Fat
2 g
Sodium
0 mg
0%
Total Carbohydrate
0 g
0%
Protein
0 g
Vitamin E
20 mg
130%
The product is found useful for the following medical conditions
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 8 Reviews
8.7
8
We explored the potential of recombinant phospholipase A5, also known as Ves v 5, to improve the diagnosis of yellow jacket venom allergies. Our study involved seven individuals, including those who had allergic reactions and those who did not. By isolating serum samples from these participants, we assessed their reactions to both bee venom and the recombinant allergens.
The production of Ves v 5 was successfully carried out in Escherichia coli, leading to the creation of soluble proteins that we then purified. We performed various tests to evaluate these proteins' functionality. This included assessing their biochemical characteristics and how well they interacted with the immune system.
Our findings highlighted the significant role of Ves v 5 in allergic reactions to hymenoptera venoms. The results suggest that recombinant proteins can be a promising alternative for diagnosing these allergies, moving away from traditional methods that rely on whole venom extracts. Ultimately, allergen-specific therapies could provide more effective and tailored treatment options for those prone to these allergies.
The production of Ves v 5 was successfully carried out in Escherichia coli, leading to the creation of soluble proteins that we then purified. We performed various tests to evaluate these proteins' functionality. This included assessing their biochemical characteristics and how well they interacted with the immune system.
Our findings highlighted the significant role of Ves v 5 in allergic reactions to hymenoptera venoms. The results suggest that recombinant proteins can be a promising alternative for diagnosing these allergies, moving away from traditional methods that rely on whole venom extracts. Ultimately, allergen-specific therapies could provide more effective and tailored treatment options for those prone to these allergies.
10
Beautiful packaging
Most Useful Review
Today I received my order. I will share my experiences regarding its use, smell, quality, size, lifespan, and benefits. The packaging is lovely and well-sealed. There's nothing in its formula that triggers my allergies. I hope to see a positive difference!
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Good
Based on 2 Reviews
8.5
5
We aimed to understand how immunoadsorption therapy, which removes certain proteins from the blood, affects individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following a COVID-19 infection.
Our study focused on 12 post-COVID patients experiencingME/CFS symptoms, heightened levels of specific autoantibodies, and neurological issues. We found that after receiving immunoadsorption therapy, there was a marked decrease in these troublesome autoantibodies associated with the autonomic nervous system.
Additionally, the therapy led to reduced levels of pro-inflammatory cytokines—substances involved in the body's immune response—which correlated with the presence of spike proteins in some patients. Despite these changes, we noted that, thirty days after therapy, while there were improvements in neuropsychological function and some physical strength, the self-reported symptoms and overall scores on ME/CFS questionnaires did not show significant improvement.
Therefore, while immunoadsorption therapy showed promise in altering certain immune markers, it did not lead to a substantial improvement in the patients' overall experience of ME/CFS.
Our study focused on 12 post-COVID patients experiencingME/CFS symptoms, heightened levels of specific autoantibodies, and neurological issues. We found that after receiving immunoadsorption therapy, there was a marked decrease in these troublesome autoantibodies associated with the autonomic nervous system.
Additionally, the therapy led to reduced levels of pro-inflammatory cytokines—substances involved in the body's immune response—which correlated with the presence of spike proteins in some patients. Despite these changes, we noted that, thirty days after therapy, while there were improvements in neuropsychological function and some physical strength, the self-reported symptoms and overall scores on ME/CFS questionnaires did not show significant improvement.
Therefore, while immunoadsorption therapy showed promise in altering certain immune markers, it did not lead to a substantial improvement in the patients' overall experience of ME/CFS.
9
Energised and active
Most Useful Review
1 people found this helpful
It's effective. I purchased it for Octacosanol after experiencing chronic fatigue syndrome for months. Just one spoon of wheat germ oil has made me feel revitalised. Recently, I was so enthusiastic that I moved some furniture myself, a task I had postponed for ages due to my lethargy.
Constipation details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
7
Diabetes management beverage study
Our exploration into the management of diabetes and its complications led us to develop a unique beverage formulation. This drink combines stevia glycoside, mogroside V, and sodium hyaluronate, known as SMH-B, which offers a sweet taste without affecting blood sugar levels.
In our study, we found SMH-B to be more than just enjoyable; it plays a key role in addressing various health issues related to diabetes. These include improving skin moisture and elasticity, alleviating constipation, and even reducing signs of depression.
Importantly, we observed that SMH-B helped lower blood glucose and lipid levels as well, proving to be a multifaceted approach to diabetes management. Such findings indicate that integrating protein in our beverage formulation could possibly enhance digestive health and symptomatic relief for those struggling with constipation.
In our study, we found SMH-B to be more than just enjoyable; it plays a key role in addressing various health issues related to diabetes. These include improving skin moisture and elasticity, alleviating constipation, and even reducing signs of depression.
Importantly, we observed that SMH-B helped lower blood glucose and lipid levels as well, proving to be a multifaceted approach to diabetes management. Such findings indicate that integrating protein in our beverage formulation could possibly enhance digestive health and symptomatic relief for those struggling with constipation.
9
Dog's constipation resolved
Most Useful Review
1 people found this helpful
This is great for my dogs’ digestion issues. I bought it for my two Siberian Huskies, one of whom had constipation problems, and this has alleviated that completely. The other one loves the taste and finishes all her food since I mix a tablespoon into the kibble. No more picky eating husky! I'll definitely buy more!
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
7.5
Clear skin results
Most Useful Review
8 people found this helpful
The condition of my skin and hair has improved, but there was one minor inconvenience. I recently took a drug containing wheat germ oil, and the results were remarkable, prompting me to continue with these capsules. Soon, my skin cleared up, and my hair became shinier. However, I experienced a constant sensation of hunger. I managed the hunger by also taking fish oil capsules alongside these. After three doses a day, the skin is completely clear, with minimal new rashes. I've ordered more supplies as there are no side effects.
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
We investigated the potential of a specific protein, PTGFRN, as a new target for chimeric antigen receptor (CAR) T-cell therapy aimed at treating glioblastoma, a type of aggressive brain tumor. Our study involved creating a library of monoclonal antibodies (mAbs) that would ideally react with cancer cells from patients while sparing healthy brain cells. Through this process, we identified mAbs that successfully targeted tumor cells in resected tissues from patients with glioblastoma.
Among the promising candidates, we focused on the mAb called 5E17, which was found to interact with tumor cells from six out of seven patients but not with any non-cancerous brain cells. We discovered that PTGFRN is the antigen recognized by this antibody. When we generated CAR-T cells based on 5E17, these engineered cells showed significant activity, producing beneficial cytokines and displaying effective tumor cell killing in lab tests. Further trials in mice injected with human-derived glioblastoma tissues demonstrated the ability of 5E17-CAR-T cells to fight tumors in a living organism.
This research suggests that PTGFRN could be a fruitful target for CAR-T cell treatments in glioblastoma patients. However, we need to approach future studies with caution to carefully evaluate any potential off-target effects this approach may have on normal tissues.
Among the promising candidates, we focused on the mAb called 5E17, which was found to interact with tumor cells from six out of seven patients but not with any non-cancerous brain cells. We discovered that PTGFRN is the antigen recognized by this antibody. When we generated CAR-T cells based on 5E17, these engineered cells showed significant activity, producing beneficial cytokines and displaying effective tumor cell killing in lab tests. Further trials in mice injected with human-derived glioblastoma tissues demonstrated the ability of 5E17-CAR-T cells to fight tumors in a living organism.
This research suggests that PTGFRN could be a fruitful target for CAR-T cell treatments in glioblastoma patients. However, we need to approach future studies with caution to carefully evaluate any potential off-target effects this approach may have on normal tissues.
9
Boosts brain health
Most Useful Review
1 people found this helpful
Excellent, I use it all the time. The ingredients include wheat germ oil, which is not widely known. At 27 years old, I've found the oil’s thickness to be high and the packaging sufficient. The benefits align exactly with the claims. Omega is incredibly beneficial for brain health. I applied it to my hair, and it greatly improved dryness and frizz, enhancing its overall condition. It's also suitable for those with cholesterol issues. I honestly recommend it; it helps in removing melasma, spots, dark circles, and skin marks, and it pairs well with other oils.
Eczema details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 6 Reviews
8.4
8
We explored the effects of a specialized moisturizer designed for eczema-prone and sensitive skin on the skin's bacterial communities. In our open-label study involving 12 participants, we focused on a formulation that includes colloidal oatmeal, a specific plant extract, and a unique protein derived from filaggrin. Participants applied the moisturizer twice daily for 21 days, and we looked at changes in their skin microbiome through cheek swab samples collected before and after the treatment.
Our findings revealed that in 10 of the participants, there was a notable increase in bacterial species richness, meaning that a greater variety of bacteria was present on their skin after using the moisturizer. Importantly, these changes did not lead to any harmful shifts in the overall makeup of the skin bacteria, suggesting a positive balance was maintained.
This implies that incorporating moisturizers with anti-inflammatory and skin-repairing properties could be beneficial for managing eczema symptoms. Overall, the study adds valuable insight into how specific ingredients might support skin health in those with sensitive conditions.
Our findings revealed that in 10 of the participants, there was a notable increase in bacterial species richness, meaning that a greater variety of bacteria was present on their skin after using the moisturizer. Importantly, these changes did not lead to any harmful shifts in the overall makeup of the skin bacteria, suggesting a positive balance was maintained.
This implies that incorporating moisturizers with anti-inflammatory and skin-repairing properties could be beneficial for managing eczema symptoms. Overall, the study adds valuable insight into how specific ingredients might support skin health in those with sensitive conditions.
9
Severe itching relief
Most Useful Review
13 people found this helpful
Helped my eczema. I started having eczema on my elbows with severe itching. I read that this oil is excellent for eczema, and it truly is. I use it after every shower and even in between.
Food Poisoning details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
We explored the effectiveness of chicken egg yolk immunoglobulin Y (IgY) in combating foodborne pathogens, a growing concern in food safety. By isolating IgY from the yolks of immunized hens using a special dilution technique, we confirmed its ability to specifically target harmful bacteria.
Our evaluations showed that IgY could significantly inhibit the growth of major foodborne pathogens. In fact, a single dose of 0.5 mg/mL of IgY managed to reduce bacterial counts by as much as 7 log in some cases. We noticed that while this dose was impactful across the board, some pathogens required repeated doses for optimal effect.
These findings suggest that chicken egg yolk IgY might serve as a sustainable and ethical alternative to traditional antibiotics in livestock management. Our next steps will involve further testing in live animals and considering large-scale production methods of IgY for practical applications in animal healthcare.
Our evaluations showed that IgY could significantly inhibit the growth of major foodborne pathogens. In fact, a single dose of 0.5 mg/mL of IgY managed to reduce bacterial counts by as much as 7 log in some cases. We noticed that while this dose was impactful across the board, some pathogens required repeated doses for optimal effect.
These findings suggest that chicken egg yolk IgY might serve as a sustainable and ethical alternative to traditional antibiotics in livestock management. Our next steps will involve further testing in live animals and considering large-scale production methods of IgY for practical applications in animal healthcare.
9
Versatile use
Most Useful Review
Excellent for food, mixtures, body, and hair. I highly recommend it! The large packaging lasts a long time.
Heart Attack details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.8
USERS' SCORE
Good
Based on 4 Reviews
8.4
2
We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
9
Moisturises heart
Most Useful Review
Mrahha, it deeply moisturises the heart.
Pelvic Pain details
SCIENTIFIC SCORE
Questionable
Based on 13 Researches
6.9
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.
Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
10
PMS pain relief
Most Useful Review
6 people found this helpful
Gorgeous butter! I’m delighted with this purchase, which I made on the advice of a nutritionist. I had a severe deficiency and took vitamin E capsules without noticeable effects. So I tried wheat germ oil. Within a couple of days, my skin rashes started to fade, and most importantly, after a week, my periods began without any pelvic pain, which is a huge victory for me. Usually, I experience strong abdominal cramps, but this time, I didn't need any pills. I wholeheartedly recommend this for anyone suffering from PMS pain. Additionally, I've found it effective for minor cuts due to its healing properties. My health is improving!
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.4
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
In our exploration of how certain natural compounds can impact rheumatoid arthritis (RA), we focused on the total flavonoids derived from Schltr., specifically identifying the effects of quercetin. Our research employed various methods, including cellular and animal models, to examine how these compounds inhibit TNF-α, a key player in inflammation and joint deterioration.
We discovered that quercetin stands out among several compounds, demonstrating a strong ability to reduce TNF-α activity. This reduction corresponds with decreased cellular injury and apoptosis in our models, showcasing quercetin's potential as a protective agent against RA symptoms. Through advanced techniques such as molecular docking and thermal profiling, we verified that quercetin binds to TNF-α, eventually diminishing the inflammatory processes related to arthritis.
The findings suggest that quercetin plays a significant role in suppressing the TNF-α/NF-κB signaling pathway, which is crucial in the development of RA. By blocking certain inflammatory responses, quercetin appears to mitigate pain and joint damage, positioning it as a hopeful candidate for RA treatment. Overall, our investigation highlights quercetin's promising properties as a natural anti-inflammatory agent for those suffering from arthritis.
We discovered that quercetin stands out among several compounds, demonstrating a strong ability to reduce TNF-α activity. This reduction corresponds with decreased cellular injury and apoptosis in our models, showcasing quercetin's potential as a protective agent against RA symptoms. Through advanced techniques such as molecular docking and thermal profiling, we verified that quercetin binds to TNF-α, eventually diminishing the inflammatory processes related to arthritis.
The findings suggest that quercetin plays a significant role in suppressing the TNF-α/NF-κB signaling pathway, which is crucial in the development of RA. By blocking certain inflammatory responses, quercetin appears to mitigate pain and joint damage, positioning it as a hopeful candidate for RA treatment. Overall, our investigation highlights quercetin's promising properties as a natural anti-inflammatory agent for those suffering from arthritis.
9
Great help
Most Useful Review
Wonderful. Simply a great, pure product that we are using for arthritis, and it has proven to be very helpful for my husband's bad back. I love that it's entirely natural.
Athlete’s Foot details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.3
8
We explored the potential of dermcidin, a natural antimicrobial protein, in fighting off Trichophyton rubrum, the fungus responsible for athlete’s foot. Our research involved testing recombinant dermcidin to evaluate its ability to inhibit the growth of this fungus. The results were quite promising, revealing that at typical sweat levels of dermcidin—about 50 μg/mL—it was able to reduce fungal growth by 40.5%. When we ramped up the concentration to 270 μg/mL, the effect amplified significantly, with a 93.4% reduction in fungal presence.
Further analysis showed that dermcidin not only kills Trichophyton but also impacts its metabolic activity, making it less effective at thriving on the skin. Interestingly, we found that individuals suffering from tinea pedis, commonly known as athlete’s foot, had lower levels of dermcidin in their sweat compared to healthy individuals. This suggests that sufficient levels of dermcidin are critical in protecting our skin against fungal infections.
Ultimately, this study highlights dermcidin's important role in skin health, particularly its potential to prevent athlete’s foot by inhibiting the growth of the fungus. It seems that maintaining adequate levels of this protein might be key to successfully combating these infections and supporting overall skin immunity.
Further analysis showed that dermcidin not only kills Trichophyton but also impacts its metabolic activity, making it less effective at thriving on the skin. Interestingly, we found that individuals suffering from tinea pedis, commonly known as athlete’s foot, had lower levels of dermcidin in their sweat compared to healthy individuals. This suggests that sufficient levels of dermcidin are critical in protecting our skin against fungal infections.
Ultimately, this study highlights dermcidin's important role in skin health, particularly its potential to prevent athlete’s foot by inhibiting the growth of the fungus. It seems that maintaining adequate levels of this protein might be key to successfully combating these infections and supporting overall skin immunity.
7.5
Improved skin softness
Most Useful Review
5 people found this helpful
I add this wheat germ oil to my daily salad rather than using olive oil, appreciating its almond flavour. The oil is additive-free and contains naturally occurring vitamin E, and is also non-GMO. I favour this brand and frequently purchase their products. Within a few days, I noticed a difference in my skin; it feels noticeably softer, and my soles feel great. I also give it to my dog by adding it directly to his food bowl.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Improved vision health
Most Useful Review
I took this oil on my doctor's advice to maintain my vitamin E levels. It was a delightful surprise, proving beneficial for my bones, teeth and joints due to its vitamin D content. Additionally, the presence of omega is noteworthy. The use of wheat germ oil effectively addresses vision problems and aids the nervous system. The manufacturer has a solid reputation, and I consistently purchase this product, being thoroughly pleased with its results.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 4 Reviews
8.3
8
Vitamin E mitigates respiratory damage
We investigated how exposure to ultrafine particles (UFPs) in cold and humid environments impacts respiratory health. Using a controlled study with male Balb/c mice, we found that exposure to carbon black nanoparticles worsened lung function and increased inflammation and oxidative stress.
Notably, the combination of UFPs and cold-humid conditions intensified these adverse effects. However, when we administered Vitamin E, it helped reduce these harmful impacts. This suggests that Vitamin E could be a potential protector against indoor air pollutants, offering insights for healthier living spaces.
Notably, the combination of UFPs and cold-humid conditions intensified these adverse effects. However, when we administered Vitamin E, it helped reduce these harmful impacts. This suggests that Vitamin E could be a potential protector against indoor air pollutants, offering insights for healthier living spaces.
9
Improved immunity
Most Useful Review
9 people found this helpful
Wheat germ oil is fantastic; this is my second purchase. It's incredibly beneficial, as I take it with pleasure. After starting, my immunity improved, and my metabolism returned to normal. It’s packed with vitamins and minerals, making me feel energised and less hungry. I apply it to my skin, and it nourishes and moisturises effectively. My children also take it; their illnesses seem milder and pass quickly. I prefer natural vitamins and frequently alternate oils. When I ran out, I felt a decline in energy and started to gain weight, but I was thrilled to have ordered it again, opting for two bottles this time. I also purchased cod liver oil to alternate with it. If you take it with the intention of benefitting, it certainly delivers.
Sleep Apnea details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Effective for insomnia
Most Useful Review
4 people found this helpful
This product has a beneficial impact, although the taste is not very pleasant. I have deducted a star due to insufficient information from Now Foods regarding the extraction process of this oil. It appears to be effective for sleep—especially for those battling insomnia. I will continue to purchase it.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.2
9
Back pain relief
Most Useful Review
This oil helped my husband significantly with his back pain. After taking it just twice, he reported a notable improvement in his back muscles, which is quite helpful.
Cancer details
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.2
8
We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
7.5
Skin cancer prevention
Most Useful Review
34 people found this helpful
The yellow colour of the oil may appear darker than others. Its texture is rather heavy, and while the quality is satisfactory, the smell resembles oatmeal and lingers. Despite this, its benefits outweigh the drawbacks, as it accelerates healing for skin wounds and burns, reduces scar appearance, alleviates itching, and helps prevent skin cancer. Additionally, it can lighten skin tone and address hair breakage and stretch marks. Being a larger package, it's advisable to use it in mixtures for hair or skin, as it should be diluted for effective use. If my comment helps, please give a like 💗
Knee Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 9 Reviews
8.1
9
CNP may ease knee osteoarthritis
We explored the potential of C-type natriuretic peptide (CNP) as a treatment for knee pain and osteoarthritis. This peptide was tested through intraarticular injections in a rat model of knee arthritis to assess its impact on cartilage degradation and persistent pain.
Our analysis revealed that CNP appears to work by targeting specific pathways in the body. Notably, we found that CNP negatively affected the IL6-STAT3 signaling pathway, which is known to contribute to inflammation and pain in the knees. Rather than interfering with other inflammatory signals, CNP selectively inhibited the mechanism that usually leads to increased pain and degradation of joint cartilage.
The findings suggest that by suppressing the expression of VEGFa, a protein associated with inflammation, CNP could provide relief from knee pain. We believe this positions CNP as an exciting candidate for further development as a disease-modifying anti-osteoarthritis drug (DMOAD). With its ability to reduce pain and protect cartilage, CNP shows promise as an innovative approach to managing knee osteoarthritis.
Our analysis revealed that CNP appears to work by targeting specific pathways in the body. Notably, we found that CNP negatively affected the IL6-STAT3 signaling pathway, which is known to contribute to inflammation and pain in the knees. Rather than interfering with other inflammatory signals, CNP selectively inhibited the mechanism that usually leads to increased pain and degradation of joint cartilage.
The findings suggest that by suppressing the expression of VEGFa, a protein associated with inflammation, CNP could provide relief from knee pain. We believe this positions CNP as an exciting candidate for further development as a disease-modifying anti-osteoarthritis drug (DMOAD). With its ability to reduce pain and protect cartilage, CNP shows promise as an innovative approach to managing knee osteoarthritis.
9
Great for joints
Most Useful Review
39 people found this helpful
I've heard so much praise for wheat germ oil and wanted to see its effects myself. It’s purported to help lighten dark areas and has been great for my joints, especially when mixed with other oils to minimise the scent. The results have been excellent.
Liver Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.3
USERS' SCORE
Good
Based on 2 Reviews
8.1
9.5
We explored the impact of engineered mesenchymal stromal cells (MSCs) on liver disease, specifically focusing on their ability to manage inflammation caused by excessive neutrophil infiltration. With conditions like autoimmune disorders and liver diseases often worsened by this inflammation, we found a remarkable way to enhance the therapeutic properties of MSCs.
By modifying these cells with P-selectin and E-selectin targeting peptides, we created a system where engineered MSCs could effectively compete with neutrophils at the site of injury. This clever design allows the MSCs to more efficiently reach the damaged liver in a mouse model of acute liver failure.
Our findings showcase that these modified MSCs not only home to the liver effectively, but they also significantly curb unnecessary neutrophil activity. This one-two punch of reducing inflammation and utilizing the MSCs' inherent healing abilities leads to better treatment outcomes. Notably, we observed an increase in certain macrophages that help inhibit neutrophils, further suggesting a multi-faceted approach to therapy. Overall, we're excited about how this strategy opens new doors for MSC-based therapies in helping repair damaged tissues.
By modifying these cells with P-selectin and E-selectin targeting peptides, we created a system where engineered MSCs could effectively compete with neutrophils at the site of injury. This clever design allows the MSCs to more efficiently reach the damaged liver in a mouse model of acute liver failure.
Our findings showcase that these modified MSCs not only home to the liver effectively, but they also significantly curb unnecessary neutrophil activity. This one-two punch of reducing inflammation and utilizing the MSCs' inherent healing abilities leads to better treatment outcomes. Notably, we observed an increase in certain macrophages that help inhibit neutrophils, further suggesting a multi-faceted approach to therapy. Overall, we're excited about how this strategy opens new doors for MSC-based therapies in helping repair damaged tissues.
7.5
Taste and health benefits
Most Useful Review
9 people found this helpful
I bought this oil for salads, and it’s simply delightful! I didn’t expect it to be so tasty. I often change my salad oils, but this one is exceptionally pleasant. It sits lightly on my stomach and feels curative for my liver and pancreas. I'm keen to order it regularly. Compared to olive oil, which feels heavy, this oil is rich yet light. I can’t quite describe my feelings otherwise.
Acne details
SCIENTIFIC SCORE
Questionable
Based on 21 Researches
6.7
USERS' SCORE
Good
Based on 9 Reviews
8
1
We explored the effectiveness of vitamin E alongside isotretinoin, a common treatment for severe acne. In an investigator-blinded, randomized study involving 82 patients, participants were divided into two groups. One group received isotretinoin alone, while the other combined it with 800 IU of vitamin E, over a period of 16 weeks.
Our main goal was to determine whether vitamin E could reduce the side-effects associated with isotretinoin, which are often bothersome for patients. Throughout the study, we assessed various mucocutaneous side effects, such as facial dryness and redness, as well as changes in serum lipid and liver enzyme levels.
Ultimately, we found no significant difference in the incidence or severity of side effects between the two treatment groups. This indicates that vitamin E did not provide any noticeable benefit when added to isotretinoin therapy for acne vulgaris.
While vitamin E is often suggested as a remedy to lighten the side effects of medications, our findings suggest that its use alongside isotretinoin may not be helpful.
Our main goal was to determine whether vitamin E could reduce the side-effects associated with isotretinoin, which are often bothersome for patients. Throughout the study, we assessed various mucocutaneous side effects, such as facial dryness and redness, as well as changes in serum lipid and liver enzyme levels.
Ultimately, we found no significant difference in the incidence or severity of side effects between the two treatment groups. This indicates that vitamin E did not provide any noticeable benefit when added to isotretinoin therapy for acne vulgaris.
While vitamin E is often suggested as a remedy to lighten the side effects of medications, our findings suggest that its use alongside isotretinoin may not be helpful.
9
Wonderful results
Most Useful Review
36 people found this helpful
This product is amazing for anyone with problematic skin! My results have been fantastic, making this my go-to choice. I mix it with honey for facials and enjoy it in the bath, leaving my skin soft and doing wonders for my acne. Having tried countless expensive treatments, I've achieved better results with wheat germ oil. If I get a pimple, it nearly disappears by morning after application. Fantastic!
Hair Loss details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 5 Reviews
8
8
We assessed the impact of a topical solution featuring essential oils, polyunsaturated fatty acids, and Vitamin E on rabbits facing skin diseases. The study included thirty New Zealand rabbits divided into two groups: one treated with the natural formula and a control group.
Over the treatment period, we observed notable improvements in hair shine, hydration, and a reduction in flaking, bad odor, and hair loss in the treatment group. In contrast, the control group showed no such benefits. Overall, this suggests that Vitamin E combined with other natural ingredients can enhance skin and hair health in rabbits.
Over the treatment period, we observed notable improvements in hair shine, hydration, and a reduction in flaking, bad odor, and hair loss in the treatment group. In contrast, the control group showed no such benefits. Overall, this suggests that Vitamin E combined with other natural ingredients can enhance skin and hair health in rabbits.
9
Softens hair
Most Useful Review
1 people found this helpful
It’s great for hair; it makes my hair soft and has reduced hair loss for me. I mixed it with olive oil, jojoba oil, tea tree oil, and castor oil.
High Cholesterol details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.3
USERS' SCORE
Good
Based on 11 Reviews
8
9
Potential atheroprotective effects of T3
We aimed to explore how pure tocotrienol (T3), a form of vitamin E, might help in fighting atherosclerosis, a condition often linked to high cholesterol. In our study, 30 rabbits were fed high-cholesterol diets and then divided into groups receiving different doses of T3 or a control without T3.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
9
Lower cholesterol effectively
Most Useful Review
1 people found this helpful
I’m extremely impressed by the quality of this Wheat Germ Oil. The pure ingredients ensure health benefits. While the taste is a bit odd at first, the health impacts are worth it. Since adding it to my routine, I've seen a significant decrease in inflammation, which is vital for heart health. As someone who favours plant-based over fish oil, this has significantly helped in managing my cholesterol levels. I highly recommend it for those looking for a natural way to support heart health and lower cholesterol.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.2
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.8
8
We investigated how long-term exposure to urban air pollution affects the recovery from ischemic stroke in mice. Our findings showed that breathing in fine particulate matter increases neuroinflammation and cardiac injury, leading to higher mortality rates after a stroke.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
9
Strengthens immunity
Most Useful Review
8 people found this helpful
Wheat germ oil is a powerhouse of vitality and nutrients, containing numerous vitamins and trace elements that positively influence the cardiovascular system. It’s known for its high vitamin E content, which acts as a powerful antioxidant. I consume it as a dietary supplement for various gastrointestinal conditions, to enhance my immune system, and for detoxification, especially after chemotherapy. I appreciate its form and pleasant taste.
