Last update
5/26/2025
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 14 Reviews
8.5
Supplement Facts
Serving Size: One Capsule
Amount Per Serving
%DV
One Capsule Contains:
Amount Per Serving
% DV
Vitamin C (as Ascorbic Acid)
500 mg
556%
Citrus Bioflavonoids
75 mg
*

Top Medical Research Studies

8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

Most Useful Reviews

9
No heartburn relief
There is no heartburn at all. The raw materials are also reliable.
Read More
9
Trustworthy quality
Family Vitamin C is easy to take and causes no heartburn. Thorne's quality is trustworthy.
Read More
9
Good experience
There is no heartburn, and it is good to eat~
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

User Reviews

USERS' SCORE
Good
Based on 14 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No heartburn relief
There is no heartburn at all. The raw materials are also reliable.
Read More
9
Trustworthy quality
Family Vitamin C is easy to take and causes no heartburn. Thorne's quality is trustworthy.
Read More
9
Good experience
There is no heartburn, and it is good to eat~
Read More
9
Family approval
We are consuming the second package and are pleased with the product. There's no heartburn, nausea, or belching. The capsules are medium-sized and easy to swallow. I also purchased this for my 76-year-old parents, and they are experiencing no side effects. We are satisfied!
Read More
9
No heartburn noted
Vitamin C without heartburn.
Read More

Frequently Asked Questions

9
No heartburn relief
There is no heartburn at all. The raw materials are also reliable.
9
Family approval
We are consuming the second package and are pleased with the product. There's no heartburn, nausea, or belching. The capsules are medium-sized and easy to swallow. I also purchased this for my 76-year-old parents, and they are experiencing no side effects. We are satisfied!
9
No heartburn noted
Vitamin C without heartburn.
9
No heartburn
I trust this brand due to its reputation. While the content per capsule is modest, it does not cause heartburn.
9
No heartburn
I take this on an empty stomach each morning with glutathione, and I don’t experience heartburn. The capsule size is perfect, making it easy to swallow.
9
Quick recovery
I took vitamin C in high doses during my first experience with this product and was pleased. After taking 2 capsules three times a day, I recovered from ARVI in just 3 days. Importantly, the capsules do not cause heartburn.
9
No heartburn issue
Sun Flavonoid Vitamin C was challenging due to heartburn with other vitamins, but I have no issues with this one, allowing me to take it comfortably.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.

References

  1. Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
image