We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
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Melatonin reduces menopause symptoms effectivelyCombination of Soy Isoflavones, 8-Prenylnaringenin and Melatonin Improves Hot Flashes and Health-Related Quality of Life Outcomes in Postmenopausal Women: Flavie Study.
High relevance for menopause management
We explored how a blend of soy isoflavones, 8-prenylnaringenin, and melatonin affects hot flashes in postmenopausal women. Over 12 weeks, 44 participants reported significant reductions in hot flash frequency and improvements in health-related quality of life.
By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
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Melatonin boosts bone healthMelatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis.
High relevance for osteoporosis research
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
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We examined the impact of melatonin on chronic dyspepsia in postmenopausal women, particularly those infected with Helicobacter pylori. The study involved 152 participants across various groups, including healthy women and those with H. pylori infection.
After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.
Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
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Melatonin shows promise for menopauseEffects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
Relevant for menopause management
We explored the role of melatonin in reducing depression and anxiety among postmenopausal women by reviewing multiple randomized controlled trials. Our analysis included five studies with 441 participants, revealing that melatonin significantly lessened symptoms of both depression and anxiety.
This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.
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