DHA alleviates epilepsy-related depression
Yang Y, Chen L, Zhang N, Zhao Y, Che H, et al. DHA and EPA Alleviate Epileptic Depression in PTZ-Treated Young Mice Model by Inhibiting Neuroinflammation through Regulating Microglial M2 Polarization and Improving Mitochondrial Metabolism. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12122079
EPA shows promise for depression
Yu Q, Li H, Chen M, Pan Y, Zhou L, et al. GPR120 internalization: a key mechanism for EPA in antidepressant action. Food Funct. 2025;16:2893. doi:10.1039/d5fo00252d
Calcitriol impacts depression positively
Wang C, Cui C, Xie X, Chen B, Feng L, et al. Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway. Psychopharmacology (Berl). 2024;241:1329. doi:10.1007/s00213-024-06565-1