H. P. Vasantha Rupasinghe
Affiliation: Department of Pathology, Dalhousie University, Halifax, NS B3H 4H7, Canada
Institution: Dalhousie University
ORCID: 0000-0003-3435-0052
Works: 260, Cited by: 18500, H-index: 76
Dr. Rupasinghe's major research contributions include elucidating the mechanism of actions of plant flavonoids in their anti-proliferative action against hepatocellular carcinoma and breast cancer; exploring the neuroprotective and cardio-protective properties of flavonoids; polyphenols-dependent antioxidant and anti-inflammatory activities of haskap anthocyanins; synthesizing novel acylated flavonoids and examining their anti-cancer, anti-inflammatory, cytoprotective and hypolipidemic properties; and identifying unique phytochemicals that can be used as anti-infective, anti-biofilm and anti-adhesive agents against Streptococcus pyogenes. His current research aims at understanding the cancer chemopreventive mechanisms of flavonoids and their metabolites. Dr. Rupasinghe's research program, which has attracted over $9M (since 2004) in external funding, has resulted in three patent filings, one license agreement, and contributions to the commercialization of over a dozen value-added food products. He has published 260+ peer-reviewed articles (Scopus author h-index 76 and total citations over 18,500; April 2025) and trained over 100 highly qualified personnel (HQP). He serves as the co-chair of the Scientific Expert Council of the Canadian Institute of Food Science and Technology (CIFST). He is a Fellow of CIFST.
Research Interests
Keywords:
Functional foods nutraceuticals phytochemicals human health value-added food processing plant flavonoids
Topics:
Plant flavonoids Cancer chemoprevention Nutraceuticals Polyphenols Antioxidants Anti-inflammatory agents
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