Supplement Facts
Serving Size: 1 Spray (Approx. 0.41 ml)
Amount Per Serving
%DV
Vitamin B12(as Methylcobalamin from Saccharomyces cerevisiae)
500 mcg
20,833%
Certified Organic Food BlendOrganic Beet (root), Organic Carrot (root), Organic Spinach (leaf), Organic Broccoli (flower & stem), Organic Tomato (fruit), Organic Kale (leaf), Organic Cabbage (leaf), Organic Parsley (leaf), Organic Brussels Sprout (leaf), Organic Green Bell Pepper (fruit), Organic Cucumber (gourd), Organic Celery (stalk), Organic Garlic (bulb), Organic Ginger (root), Organic Onion (root), Organic Cauliflower (flower & stem), Organic Asparagus (flower & stem), Organic Strawberry (fruit), Organic Cherry (fruit), Organic Blackberry (fruit), Organic Blueberry (fruit), Organic Raspberry (fruit)
2 mg
+
The product is found useful for the following medical conditions
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.8
USERS' SCORE
Excellent
Based on 8 Reviews
9
9
We examined a case of a 51-year-old Ugandan man who experienced recurring lower limb weakness linked to pernicious anemia, an autoimmune condition causing vitamin B12 deficiency. After initial treatments, his symptoms reappeared, leading to further testing that confirmed the diagnosis.
Treatment with vitamin B12 injections significantly improved his condition. This case emphasizes the need for healthcare providers to recognize the signs of vitamin B12 deficiency early, particularly in resource-limited settings, to ensure timely diagnosis and treatment.
Treatment with vitamin B12 injections significantly improved his condition. This case emphasizes the need for healthcare providers to recognize the signs of vitamin B12 deficiency early, particularly in resource-limited settings, to ensure timely diagnosis and treatment.
10
B12 normalised
Most Useful Review
144 people found this helpful
According to the test results, my child was deficient in B12, which I ordered upon the doctor's recommendation. This vitamin is fantastic and has a pleasant taste, so my child takes it willingly. After 14 days, my child's B12 levels were back to normal—what a relief!
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.6
USERS' SCORE
Good
Based on 10 Reviews
8.6
0
Vitamin B12 ineffective for CFS
We explored the effectiveness of high-dose vitamin B12 injections on chronic fatigue syndrome (CFS) through two case reports that utilized N of 1 trials. This approach allowed us to make tailored treatment decisions based on individual responses to the therapy.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
9
Fatigue improvement
Most Useful Review
196 people found this helpful
I find these vitamins effective. The vitamin B12 spray is convenient for children—no injections or pills needed. As I have low hemoglobin and do not eat meat, I thought these would benefit me. I experienced no allergies or gastrointestinal changes. My hair stopped falling out after a month, and the chronic fatigue syndrome vanished.
Leg Cramps details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Nervous pain healed
Most Useful Review
5 people found this helpful
Very good! The nerve pain at the base of my leg has healed and I’m extremely pleased!
Cough details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.5
USERS' SCORE
Good
Based on 3 Reviews
8.5
7
We explored the connection between vitamin B-12 deficiency and chronic cough, examining how this condition might contribute to persistent coughing in some individuals. Our study involved assessing 42 patients suffering from unexplained chronic cough, 27 of whom had vitamin B-12 deficiency, while the remaining 15 did not.
By measuring their responses to inhaled histamine, we identified thresholds for laryngeal sensitivity, bronchial response, and cough reflex before and after two months of vitamin B-12 injections. The results highlighted that patients with vitamin B-12 deficiency showed heightened sensitivity, which might indicate that this deficiency plays a role in sensory nerve issues related to chronic cough.
Notably, we observed that markers of nerve growth increased in pharyngeal biopsies of patients with vitamin B-12 deficiency, supporting the idea that these changes may be linked to their chronic cough. This suggests that addressing vitamin B-12 deficiency could be an important factor in managing persistent coughs, especially when other causes remain unidentified.
By measuring their responses to inhaled histamine, we identified thresholds for laryngeal sensitivity, bronchial response, and cough reflex before and after two months of vitamin B-12 injections. The results highlighted that patients with vitamin B-12 deficiency showed heightened sensitivity, which might indicate that this deficiency plays a role in sensory nerve issues related to chronic cough.
Notably, we observed that markers of nerve growth increased in pharyngeal biopsies of patients with vitamin B-12 deficiency, supporting the idea that these changes may be linked to their chronic cough. This suggests that addressing vitamin B-12 deficiency could be an important factor in managing persistent coughs, especially when other causes remain unidentified.
9
Improved cough health
Most Useful Review
Great ingredients that are high-quality and tasty. The convenience of the packaging is noteworthy, and I've noticed significant health benefits. The dosage is better, and I can crush it easily. It’s suitable for children aged 4-12 and serves as a good additive. The frequency of use works well for treating viral pneumonia and cough. While the volume isn’t large enough for all children, the overall quality has improved their health.
Flu details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Effective for flu
Most Useful Review
I've been using all Garden of Life sprays for a couple of years now, and they have been incredibly helpful for my severe sore throat and general malaise. They are organic and completely natural, proving effective for flu, colds, inflamed glands, fever, etc. Some reviews mention mould on the spray lid or bottle, but I've not experienced this. If you keep the top clean and wipe it before each use, you won't encounter mould issues. Avoid touching the spray nozzle with your tongue or saliva, as this can lead to bacteria buildup. Keep your bottle clean, and all should be well. I will continue purchasing these handy sprays as they are compact and work well for me. I highly recommend them.
Hair Loss details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
Stopped shedding quickly
Most Useful Review
I suffered from hair loss due to a lack of vitamin B12, and this product works wonderfully! I noticed a difference in the first week, and within two weeks, the shedding stopped completely.
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Numbness relief
Most Useful Review
Garden of Life is my preferred brand; I enjoy all their products. After taking B12 for two weeks, the numbness in my arms and legs disappeared—previously, my limbs would swell after five minutes in one position, and I experienced "chills" and tingling sensations. Remarkably, my memory improved as well. People often wonder about the large dose of methylcobalamin (20338%); it's due to its poor absorption rate—around 1% of what is taken. The raspberry flavour is pleasant and is also suitable for individuals with Asperger's syndrome.
Anxiety details
SCIENTIFIC SCORE
Questionable
Based on 15 Researches
6.7
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Sake yeast shows potential for anxiety
We explored the potential benefits of Japanese sake yeast on anxiety and depression in mice subjected to stress. Over a week, we treated the mice with different doses of sake yeast and assessed its effects on anxiety, mood, and sleep.
Our findings indicated that the yeast improved anxiety and antidepressant-like behaviors, particularly at higher doses. It also increased sleep duration and influenced certain brain levels related to mood. However, the overall results suggest that while sake yeast shows promise, it may not significantly alter all biological markers associated with stress.
Our findings indicated that the yeast improved anxiety and antidepressant-like behaviors, particularly at higher doses. It also increased sleep duration and influenced certain brain levels related to mood. However, the overall results suggest that while sake yeast shows promise, it may not significantly alter all biological markers associated with stress.
7.5
Quick anxiety relief
Most Useful Review
4 people found this helpful
Fast Relief for your Nerves! My sister mentioned this product to me, and it helps greatly with my nerves and anxiety. A couple of sprays really seems to provide me with more tolerance on those days I feel overwhelmed.
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
7.5
Sore throat relief
Most Useful Review
Good for the throat. If you have a sore throat, spray this, and it will make you feel better! It's sweet and delicious!
Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
8
We explored the potential effects of vitamin B12 on cold sensitivity in a study using rats with induced neuropathic pain. The focus was to see whether vitamin B12, both alone and in combination with the pain reliever diclofenac, could alleviate cold and mechanical allodynia—a condition where non-painful stimuli are perceived as painful.
In our approach, we administered vitamin B12 in varying doses over ten consecutive days following nerve injury. What we discovered was quite telling. Higher doses of vitamin B12 (50, 100, and 200 µg kg(-1)) led to a reduction in cold sensitivity. However, when using a lower, subanalgesic dose (25 µg kg(-1)), vitamin B12 did not significantly impact pain responses when paired with low doses of diclofenac.
As we adjusted the vitamin B12 dosage to a more effective level (100 µg kg(-1)), we noticed an improvement in pain relief compared to diclofenac alone. These findings suggest that vitamin B12 could have a positive effect on alleviating cold-related pain in neuropathic conditions, especially when used at appropriate doses.
In our approach, we administered vitamin B12 in varying doses over ten consecutive days following nerve injury. What we discovered was quite telling. Higher doses of vitamin B12 (50, 100, and 200 µg kg(-1)) led to a reduction in cold sensitivity. However, when using a lower, subanalgesic dose (25 µg kg(-1)), vitamin B12 did not significantly impact pain responses when paired with low doses of diclofenac.
As we adjusted the vitamin B12 dosage to a more effective level (100 µg kg(-1)), we noticed an improvement in pain relief compared to diclofenac alone. These findings suggest that vitamin B12 could have a positive effect on alleviating cold-related pain in neuropathic conditions, especially when used at appropriate doses.
9
Immediate cold relief
Most Useful Review
6 people found this helpful
Love this B12! My family is vegan, so we need a B vitamin that is easily processed, vegan, and affordable. We adore this spray. During a period of 1-2 months without it, I noticed a significant change. Oddly, my skin broke out with pimples, I felt exhausted, and I caught 2 colds, which is unusual for me. After just one week of daily use, my skin and energy returned to normal, and the cold vanished! I won't go without it again.
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.2
USERS' SCORE
Good
Based on 12 Reviews
8.3
9
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
9
No allergies noted
Most Useful Review
196 people found this helpful
The impression of these vitamins is positive. The vitamin B12 comes in a convenient spray format, making it easy to administer to children without injections or pills. As I have low hemoglobin and don't consume meat, I found these vitamins helpful. There were no allergies or gastrointestinal issues, and my hair stopped falling out after a month. Chronic fatigue also disappeared.
Back Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 17 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.3
9
We evaluated the effectiveness of intramuscular vitamin B12 in treating low back pain among 60 patients aged 18 to 65 with mechanical pain lasting at least six months.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
9
Effective B12 treatment
Most Useful Review
1 people found this helpful
Perfectly raises vitamin B12 levels. I was deficient and purchased this spray, which provides 500 mcg per puff under the tongue for better absorption. It effectively boosted my B12, allowing me to quickly recover. Now, for prevention, I take one puff at times and two doses once a month under the tongue.
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.3
USERS' SCORE
Good
Based on 6 Reviews
8.3
8
We conducted a case-control study to investigate the link between vitamin B12 serum levels and migraine, which affects so many people but lacks a fully understood cause. Our research included 90 individuals experiencing migraines—split into those with chronic migraines and those with episodic migraines—matched against 90 healthy participants.
We measured vitamin B12 serum levels using a reliable testing method and explored how these levels correlated with migraine intensity, as assessed by two measuring scales. Notably, we found that migraine sufferers had significantly lower levels of vitamin B12 compared to those without migraines.
Chronic migraine patients specifically had even lower vitamin B12 levels than their episodic counterparts. Additionally, there was a noteworthy negative correlation; as vitamin B12 levels decreased, the severity of migraine attacks increased. These findings suggest that vitamin B12 deficiency may have an important relationship with migraine experiences, emphasizing the need for further studies to explore this connection in detail.
We measured vitamin B12 serum levels using a reliable testing method and explored how these levels correlated with migraine intensity, as assessed by two measuring scales. Notably, we found that migraine sufferers had significantly lower levels of vitamin B12 compared to those without migraines.
Chronic migraine patients specifically had even lower vitamin B12 levels than their episodic counterparts. Additionally, there was a noteworthy negative correlation; as vitamin B12 levels decreased, the severity of migraine attacks increased. These findings suggest that vitamin B12 deficiency may have an important relationship with migraine experiences, emphasizing the need for further studies to explore this connection in detail.
9
Energy and relief
Most Useful Review
17 people found this helpful
My 17-year-old son had fatigue, headaches, and dry lips. After trying this product, I noticed he had more energy and his dry lips improved. He hasn't had any headaches since starting this, so I believe it genuinely works!
Autism details
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.4
USERS' SCORE
Good
Based on 4 Reviews
8.2
4
We conducted a study that examined the levels of vitamin B12, homocysteine, and anti-parietal cell antibodies in children diagnosed with autism spectrum disorder (ASD) compared to a control group. Our research included 69 children, where 36 had ASD, and 33 were matched controls based on age, sex, and socioeconomic status. The severity of autism was assessed using the Childhood Autism Rating Scale (CARS), while serum levels were measured using a common laboratory technique called enzyme-linked immunosorbent assay.
Our findings revealed that children with ASD had significantly lower levels of vitamin B12 and homocysteine compared to their peers in the control group. However, we found no significant difference in the levels of anti-parietal cell antibodies, which suggests that vitamin B12 deficiency may not be due to absorption issues related to these antibodies. While we observed notable micronutrient deficiencies, it’s important to clarify that the study did not establish a direct benefit of vitamin B12 treatment for autism symptoms.
Importantly, this research hints at the potential role that vitamin B12 deficiencies may play in the clinical features of autism. Nonetheless, we believe that further studies involving larger populations are necessary to better understand how these micronutrient levels might influence the condition and its underlying causes.
Our findings revealed that children with ASD had significantly lower levels of vitamin B12 and homocysteine compared to their peers in the control group. However, we found no significant difference in the levels of anti-parietal cell antibodies, which suggests that vitamin B12 deficiency may not be due to absorption issues related to these antibodies. While we observed notable micronutrient deficiencies, it’s important to clarify that the study did not establish a direct benefit of vitamin B12 treatment for autism symptoms.
Importantly, this research hints at the potential role that vitamin B12 deficiencies may play in the clinical features of autism. Nonetheless, we believe that further studies involving larger populations are necessary to better understand how these micronutrient levels might influence the condition and its underlying causes.
7.5
Child enjoys vitamin
Most Useful Review
2 people found this helpful
Great for a child with autism. I take B12 as part of our treatment protocol, and it's an excellent vitamin. It's ideal for daily use. After reading reviews, I decided to order it, and it arrived quickly. I'm pleased with the purchase and will continue to use it for my child. It’s a vital vitamin for our bodies and comes in the best spray formula with raspberry flavour, which my child really enjoys.
Anemia details
SCIENTIFIC SCORE
Moderately Effective
Based on 25 Researches
8.3
USERS' SCORE
Good
Based on 36 Reviews
8.1
9.5
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
9
Convenient anaemia solution
Most Useful Review
196 people found this helpful
I have a positive impression of these vitamins. The vitamin B12 spray format is convenient for children, avoiding injections or pills. As someone with low hemoglobin and a restricted diet, I find these vitamins helpful. No side effects, and after a month, my hair stopped falling out, and chronic fatigue disappeared.
Celiac details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.1
7.5
Boosted energy levels
Most Useful Review
I've been using the Garden of Life MyKind Organics B-12 Organic Spray in Raspberry flavour for several months, and it's now a vital part of my routine. The compact 2 fl oz bottle lasts ages, and the delicious flavour makes it a delightful experience. Unlike tablets, this spray is convenient and promotes quick absorption. Since starting it, I’ve experienced a noticeable increase in my energy and mood. This organic, non-GMO product is free from any synthetic fillers. I highly recommend it for anyone looking for a natural B-12 supplement.
Hypothyroidism details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
5.2
USERS' SCORE
Good
Based on 5 Reviews
8.1
7
We explored the connection between vitamin B12 deficiency and hypothyroidism through a focused study involving 100 hypothyroid patients. This research took place over a year and aimed to determine how common vitamin B12 deficiency is among these individuals and how it correlates with thyroid antibodies.
Our findings revealed that a significant 68% of the hypothyroid patients were vitamin B12 deficient. Interestingly, a large majority of these deficient patients were female, specifically 73.5%. Additionally, we noted that a high percentage of patients with elevated Anti TPO and Anti Thyroglobulin antibodies also had low vitamin B12 levels.
Although vitamin B12 deficiency was present in a notable portion of the hypothyroid population, we're careful to point out that the study does not state that vitamin B12 supplementation alone can fully alleviate hypothyroid symptoms. However, it suggests that addressing this deficiency could be a valuable addition to current hypothyroid treatments. By recognizing and treating vitamin B12 deficiency, we may improve the overall management of hypothyroid conditions for some patients.
Our findings revealed that a significant 68% of the hypothyroid patients were vitamin B12 deficient. Interestingly, a large majority of these deficient patients were female, specifically 73.5%. Additionally, we noted that a high percentage of patients with elevated Anti TPO and Anti Thyroglobulin antibodies also had low vitamin B12 levels.
Although vitamin B12 deficiency was present in a notable portion of the hypothyroid population, we're careful to point out that the study does not state that vitamin B12 supplementation alone can fully alleviate hypothyroid symptoms. However, it suggests that addressing this deficiency could be a valuable addition to current hypothyroid treatments. By recognizing and treating vitamin B12 deficiency, we may improve the overall management of hypothyroid conditions for some patients.
9
Improvement noticed
Most Useful Review
This supplement worked wonders for my hypothyroidism and B12 deficiency. After a two-month course, my results improved significantly, and my naturopath was pleased. The goitre I thought was normal has reduced, and my husband's levels improved as well. We'll continue taking B12 until it's optimal.
Tinnitus details
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.4
USERS' SCORE
Good
Based on 4 Reviews
8.1
1
We conducted a double-blind clinical trial with 140 patients suffering from idiopathic tinnitus to gauge the effectiveness of vitamin B12. Participants were divided into two groups, one receiving vitamin B12 and the other a placebo over a month.
We evaluated tinnitus severity through questionnaires at multiple intervals. However, our findings revealed that vitamin B12 did not significantly reduce tinnitus severity compared to the placebo.
Ultimately, our study suggests that vitamin B12 may not be a beneficial treatment for tinnitus, as the results showed no noteworthy improvements.
We evaluated tinnitus severity through questionnaires at multiple intervals. However, our findings revealed that vitamin B12 did not significantly reduce tinnitus severity compared to the placebo.
Ultimately, our study suggests that vitamin B12 may not be a beneficial treatment for tinnitus, as the results showed no noteworthy improvements.
9
Tinnitus improvement
Most Useful Review
It's excellent! Although I haven't tested my B12 levels, my tinnitus and tachycardia have diminished. I appreciate the convenient sweet berry spray for taking the vitamin.
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 3 Reviews
8
7
We investigated how β-glucans derived from Saccharomyces cerevisiae can impact bone loss and metabolic health. In our study, diabetic rats underwent a treatment regimen of β-glucans for 28 days.
We observed that these glucans significantly reduced the loss of alveolar bone in both diabetic and non-diabetic groups, as well as lowered blood glucose and triglyceride levels. Additionally, they appeared to improve metabolic markers related to inflammation and bone health.
Overall, β-glucans show promise for enhancing both metabolic and periodontal health in diabetic conditions.
We observed that these glucans significantly reduced the loss of alveolar bone in both diabetic and non-diabetic groups, as well as lowered blood glucose and triglyceride levels. Additionally, they appeared to improve metabolic markers related to inflammation and bone health.
Overall, β-glucans show promise for enhancing both metabolic and periodontal health in diabetic conditions.
7.5
Reduced body pain
Most Useful Review
This is excellent for alleviating bone pain if you have low vitamin B levels. I purchase vitamin B frequently, and I believe this is one of the best I have had.
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8
9
We explored how methylcobalamin, a form of vitamin B12, impacts liver disease, particularly in the context of cholestatic liver failure. The study utilized high-throughput screening to identify methylcobalamin as a specific inhibitor of gasdermin E (GSDME), a protein that plays a key role in pyroptotic cell death—a form of inflammatory cell death contributing to liver damage.
Our findings showed that when tested on mouse models with liver failure due to cholestasis, cisplatin, or concanavalin A, methylcobalamin effectively reduced liver damage. It significantly lowered liver transaminase levels, indicating less liver inflammation and cellular injury, and helped alleviate overall liver cell death.
Furthermore, methylcobalamin worked by preventing the cleavage of GSDME, which is essential for uncontrolled inflammatory cell death. By binding to a specific site on the GSDME protein, it blocked the interactions that trigger this damaging process. Overall, our study highlighted the potential of methylcobalamin as a promising therapeutic option for managing cholestatic liver failure and related conditions.
Our findings showed that when tested on mouse models with liver failure due to cholestasis, cisplatin, or concanavalin A, methylcobalamin effectively reduced liver damage. It significantly lowered liver transaminase levels, indicating less liver inflammation and cellular injury, and helped alleviate overall liver cell death.
Furthermore, methylcobalamin worked by preventing the cleavage of GSDME, which is essential for uncontrolled inflammatory cell death. By binding to a specific site on the GSDME protein, it blocked the interactions that trigger this damaging process. Overall, our study highlighted the potential of methylcobalamin as a promising therapeutic option for managing cholestatic liver failure and related conditions.
9
Salvation for deficiency
Most Useful Review
1 people found this helpful
An essential vitamin for the body, especially for those with liver disease. This product provides effective support and can be a real lifesaver!
Depression details
SCIENTIFIC SCORE
Questionable
Based on 21 Researches
6.9
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.8
8
We explored the connection between vitamin B levels and depression in older adults over four years. Our study followed nearly 3,850 participants and found that those with low blood levels of vitamin B were significantly more likely to report depressive symptoms. Specifically, individuals with low vitamin B had a 51% higher chance of developing depression compared to those with adequate levels.
However, we did not find any significant link between folate levels and depression. These insights suggest that boosting vitamin B might be a simple, cost-effective way to help improve mental health in older adults.
However, we did not find any significant link between folate levels and depression. These insights suggest that boosting vitamin B might be a simple, cost-effective way to help improve mental health in older adults.
9
Postpartum support noted
Most Useful Review
The cast form is suitable for both children and adults, and it helped me avoid postpartum depression. Take strictly as your doctor advises!
Heart Disease details
SCIENTIFIC SCORE
Questionable
Based on 10 Researches
6.2
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.5
8
We explored the potential of high doses of vitamin B12 to protect against heart damage caused by ischemia/reperfusion injury. By researching mice subjected to heart injury, we found that vitamin B12 showed promising effects in reducing oxidative stress and improving heart function.
Our findings suggest that this vitamin works through specific pathways that lessen inflammation and cell death in heart tissue. However, more studies are needed to fully understand its therapeutic value in treating heart disease.
Our findings suggest that this vitamin works through specific pathways that lessen inflammation and cell death in heart tissue. However, more studies are needed to fully understand its therapeutic value in treating heart disease.
9
Positive heart effects
Most Useful Review
3 people found this helpful
I chose this natural vitamin because of its pleasant raspberry taste. Taking it once a day under the tongue has positively affected my heart muscles, thyroid glands, immunity, and blood pressure, while providing antiallergenic, antitoxic, and antitumour benefits. Despite B12 being poorly absorbed, this form worked well for me, alleviating muscle aches and pains.
Heart Attack details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.9
USERS' SCORE
Medium or Average
Based on 5 Reviews
6.8
9.5
β-Glucan shows cardioprotective effects
We explored whether pretreatment with β-glucan, a compound from the yeast Saccharomyces cerevisiae, could shield against heart damage induced by isoprenaline in rats. Through a well-structured experiment involving control and treatment groups, we discovered that β-glucan significantly reduced heart strain by improving cardiac markers and minimizing harmful changes in heart tissue.
This suggests that β-glucan has the potential to aid in preventing damage from heart attacks. However, it’s essential to note that more research is needed to see if these promising results can translate to humans.
This suggests that β-glucan has the potential to aid in preventing damage from heart attacks. However, it’s essential to note that more research is needed to see if these promising results can translate to humans.
7.5
Prevents heart attack
Most Useful Review
1 people found this helpful
Vitamin B12 is essential as it helps alleviate pain and prevents pernicious anaemia, heart attack, and stroke. It can assist in treating nervous disorders, anaemia, depression, hypertension, and sclerosis. The quality is excellent, the ingredients are natural, and I appreciate the attractive packaging and health benefits, especially for the price. The benefits are remarkable, and the size is convenient with a pleasant taste.
