Jarrow Formulas Milk Thistle 150 mg

We investigated the effects of silymarin on liver and heart health under oxidative stress from paracetamol. In a controlled study with 28 male mice, silymarin showed a strong potential to reduce liver injury markers and improve liver enzyme levels after treatment.

Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.

9.5

Liver health improvement

Most Useful Review

Milk thistle is highly effective for healing liver cells and detoxifying the body. It aids in cleansing blood vessels and alleviates constipation. I find that it assists with liver disease, dysbiosis, and other issues. I take it for 2-3 months biannually, and it significantly enhances my well-being. The dosage is also favourable.

Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum.

Most Relevant Research

We examined the effects of Silybum marianum (SM) on heart health through a study on pigs with myocardial infarction. Our findings revealed that administering SM for ten days significantly lowered plasma triglycerides and reduced triglyceride absorption.

Notably, this outcome correlated with reduced cardiac lipotoxicity three weeks after the heart incident and better cardiac structure. Importantly, we observed no adverse effects from SM. Overall, while SM shows promise in improving certain heart conditions, further research could clarify its broader application.

8.8

Liver detoxification

Most Useful Review

I recommend Milk Thistle as it effectively treats food poisoning, chronic intoxication, and is beneficial for acquired immunodeficiencies, diabetes, obesity, and to mitigate the risk of cardiovascular disease. It aids in cleansing the liver, blood, and body of toxins, particularly after chemotherapy or radiation therapy.

Chest Pain

Best of all, it alleviated my right-side aches in my stomach. After discovering I have a fatty liver through photography, I've experienced no pain in the liver after a week of use. I feel better, and the tinnitus in my ears is less noticeable. I no longer have fatigue and can get up at 5 in the morning for prayer without any issue.

Ear Infection

I purchased this complex due to persistent ringing in my ears, weakness, and headaches. It helped alleviate the ringing, but after six months, I encountered the same problem again. I need to reorder as I want to address the ear infection.

Gout

Good for liver support and has helped my husband reduce his gout issues.

Heart Disease

SCIENTIFIC SCORE

Moderately Effective

Based on 8 Researches

2,3-dehydrosilybin shows heart protection

Cardioprotective effect of 2,3-dehydrosilybin preconditioning in isolated rat heart.

Most Relevant Research

We investigated the potential heart health benefits of 2,3-dehydrosilybin (DHS), a component of silybum marianum. In our study, rats' isolated hearts were treated with low doses of DHS before experiencing induced heart attacks and subsequent recovery.

The results showed that DHS significantly reduced heart tissue damage compared to untreated hearts, suggesting it has a protective effect. This effect is linked to specific signaling pathways in the heart. Overall, our research highlights the promising cardioprotective properties of this natural compound.

8.8

Reduces bad cholesterol

Most Useful Review

Milk thistle helps to lower bad cholesterol (LDL), which in turn protects against heart disease. It can be taken alongside cholesterol medications, due to its beneficial effects on liver health, as liver issues are a known side effect of these medications.

Tinnitus

Reduced tinnitus severity

Most Useful Review

Best of all, it relieved my stomach aches on the right side. After discovering I have a fatty liver, I noticed that after a week of use, I experience no liver pain and feel better overall. My tinnitus has also lessened, and I no longer feel fatigued; I can wake up at 5 in the morning for prayer without any issues.

Food Poisoning

It works! Whenever I eat fried food or have reactions due to junk food or gluten, I take this pill. It helps to soothe the liver. I also have a mild reaction to shrimp, and this assists in calming the irritation without inflaming my liver enzymes. Milk thistle targets the liver, helping to reduce and balance the toxins. Always have your liver checked through blood tests and ultrasounds, eat well, and exercise.

High Cholesterol

SCIENTIFIC SCORE

Possibly Effective

Based on 16 Researches

Silymarin positively influences cholesterol

Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial.

Most Relevant Research

We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.

Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.

However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.

9.5

Liver recovery aid

Most Useful Review

I have found that Milk Thistle is beneficial for my liver health. It is best taken after meals, and I usually take 2 tablets before bed, especially after drinking. It has helped me recover quickly, particularly from the effects of high cholesterol.

Irritable Bowel Syndrome

Effective supplement for IBS relief

Retrospective analysis of the effects of a highly standardized mixture of Berberis aristata, Silybum marianum, and monacolins K and KA in diabetic patients with dyslipidemia.

Most Relevant Research

We explored the effects of a supplement called Berberol®K, which contains silybum marianum, on patients dealing with irritable bowel syndrome (IBS) alongside diabetes and dyslipidemia.

In a retrospective study with 59 subjects, those who were treated showed notable improvements after six months, including reduced diarrhea symptoms.

The results suggest that this food supplement could be beneficial, especially for those who cannot tolerate standard treatments like statins.

9.5

Immediate relief

Most Useful Review

I suffer from severe Myofascial Pain Syndrome (MPS), which causes very painful muscle knots known as trigger points. After taking three capsules of Milk Thistle three times a day, I noticed an immediate improvement, particularly regarding vertigo and toxicity. This allowed my clinician to increase my trigger point injections significantly, from about four or five to tolerating 180 per session, twice a week. Eventually, I reduced to the recommended dosage of just three capsules a day when the toxic load decreased.

Autoimmune Disorder

SCIENTIFIC SCORE

Moderately Effective

Based on 9 Researches

Silybin shows promise for autoimmune disorders

Silybin Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Dendritic Cell Activation and Th17 Cell Differentiation.

Most Relevant Research

We investigated how silybin, a unique flavonoid found in certain plants, impacts autoimmune disorders, specifically using a model for multiple sclerosis called experimental autoimmune encephalomyelitis (EAE).

In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.

The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.

9.5

Reduces fatigue

Most Useful Review

I find Jarrow brand Milk Thistle to be the best for my excessive daytime sleepiness disorder. I can safely take one capsule three times a day, which helps alleviate my tiredness. Within 45 minutes of taking a capsule, I feel more awake. Just remember not to exceed three capsules a day.