Jarrow Formulas Milk Thistle

2 people found this helpful

I purchased milk thistle for raised liver enzymes due to non-alcoholic fatty liver disease. My blood tests showed impressive improvement. I temporarily stopped taking it to save money but had to restart as my levels rose. It's now non-negotiable in my routine.

2 people found this helpful

Bloating details

Acquired on recommendation. The first week was tense, experiencing nausea and a strong mouth odour. I was advised to take it with a sorbent for the first two weeks. Despite that, after the treatment, I felt light, the bloating vanished, and the mouth odour dissipated. My tongue became clearer, and surprisingly, my skin improved significantly, being much cleaner and less oily. Overall, I'm satisfied but wouldn't risk taking it without a doctor's advice. I take one capsule daily, cautious about increasing the dosage due to potential kidney issues.

1 people found this helpful

Candidiasis details

I purchased this to help prevent die-off symptoms when eradicating Candida, which can increase toxins and strain the liver. I take milk thistle supplements as they are effective for liver support during this process.

Great supplement! This extract ratio is excellent. Beyond its known benefits, I recommend this to everyone battling cancer! It reduces the side effects of chemotherapy and promotes a better quality of life.

Chemotherapy details

Premenstrual Syndrome details

Effective liver support

6 people found this helpful

Very happy. After completing a month-long course, I was pleased with this milk thistle. I won’t go into too much detail, but regarding the female side of things, particularly concerning the cycle and premenstrual syndrome, everything functioned admirably. Estrogen metabolism occurs in the liver, so by supporting its function, it helps ease the manifestations of estrogen dominance. My skin was also in good condition during the treatment. In today’s world, virtually everyone requires liver support due to the vast number of toxins present, thus I plan to undertake courses every six months.

Updated: Apr 2026

Allergies details

Silibinin shows promise for asthma

Moderately Effective

Based on 4 Researches

Choi YH, Jin GY, Guo HS, Piao HM, Li Lc, et al. Silibinin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2012;427:450. doi:10.1016/j.bbrc.2012.07.112

We examined how silibinin, a compound found in milk thistle, affects allergic asthma in a mouse model. Our findings showed that silibinin significantly helped reduce airway inflammation and hyperresponsiveness, mainly by targeting the NF-κB pathway. This suggests that silibinin might offer protective benefits against allergic airway conditions by moderating inflammatory responses. While our research found promising results in mice, further studies are necessary to confirm its effectiveness in human asthma treatment.

7.5

Improves allergy symptoms

Most Useful Review

1 people found this helpful

I bought it for the first time to tidy up the liver and detox my body. As a child, I often consumed milk thistle syrup, but it contained a lot of sugar. Now, upon discovering this supplement, I ordered it immediately, and it aids me with allergies and bile issues. Good absorption and incredible benefits, but a month-long course is necessary, followed by a break. The product quality is satisfactory, with small capsules that are easy to swallow and minimal taste or smell. I recommend it.

Updated: Mar 2026

Leg Cramps details

1 people found this helpful

Excellent! I purchased vitamin D3 due to my decreased immunity and pain in my legs and lower back. One capsule daily is sufficient to keep me cheerful, with reduced pain in my knees and lower back. The product quality is excellent, and I highly recommend it!

Updated: Mar 2025

Chest Pain details

7 people found this helpful

Best of all, it alleviated my right-side aches in my stomach. After discovering I have a fatty liver through photography, I've experienced no pain in the liver after a week of use. I feel better, and the tinnitus in my ears is less noticeable. I no longer have fatigue and can get up at 5 in the morning for prayer without any issue.

Diabetes details

Silibinin shows potential for diabetes

Possibly Effective

Based on 16 Researches

Zare Mehrjerdi P, Asadi S, Ehsani E, Askari VR, Baradaran Rahimi V. Silibinin as a major component of milk thistle seed provides promising influences against diabetes and its complications: a systematic review. Naunyn Schmiedebergs Arch Pharmacol. 2024;397:7531. doi:10.1007/s00210-024-03172-x

We explored the effects of silibinin, a key component from milk thistle, on diabetes through various studies. The systematic review covered data from multiple databases and highlighted that silibinin can help lower blood glucose levels, reduce insulin resistance, and improve inflammatory responses.

It also showed promise in tackling diabetes complications like liver damage and neuropathy. Despite these encouraging results, it's important to note that further well-structured studies are needed to fully understand how silibinin works in managing diabetes effectively.

7.5

Joint and vision support

Most Useful Review

3 people found this helpful

Milk thistle is renowned for its protective properties, containing flavonoids and silymarin. It's beneficial for both types of diabetes, joint problems, vision issues, and digestive disorders. Research shows that silymarin acts as a natural antioxidant with antiviral properties, fighting inflammation and supporting overall health.

Updated: Mar 2026

Hepatitis details

Milk thistle shows potential in treatment

Questionable

Based on 3 Researches

Payer BA, Reiberger T, Rutter K, Beinhardt S, Staettermayer AF, et al. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Clin Virol. 2010;49:131. doi:10.1016/j.jcv.2010.07.006

We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.

While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.

These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.

Liver cleansing benefits

Most Useful Review

338 people found this helpful

Milk thistle is the most valuable product for healing liver cells and the entire organism. It cleanses blood vessels and removes toxins from the body. This fibre activates the bowels and aids in dysbacteriosis, hemorrhoids, hepatitis, and varicose veins. I take it in courses for 2-3 months every half a year and feel much better with it. A favourable dosage and quantity.

Updated: Mar 2026

Cancer details

Investigating silibinin's cancer treatment role

Possibly Effective

Based on 16 Researches

Li P, Wang D, Yang X, Liu C, Li X, et al. Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Molecules. 2024;29. doi:10.3390/molecules29081901

We aimed to uncover how silibinin, a compound from milk thistle, impacts cancer, specifically in adenoid cystic carcinoma cells and Balb/c nude mice. The study identified 75 key targets linked to tumor growth and showcased that silibinin significantly reduced cell viability, proliferation, and migration.

Additionally, it induced cancer cell death and inhibited tumor growth in live subjects. Our findings highlighted how silibinin acts on specific proteins affecting cancer pathways, offering valuable insights into its potential as an anti-tumor treatment.

Improved quality of life

Most Useful Review

Great supplement. This extract ratio is very good. Apart from its known benefits, I recommend this to everyone battling Cancer! It reduces the side effects of chemotherapy and enhances quality of life.

Updated: Apr 2026

Swollen Lymph Nodes details

Improved facial tightness

3 people found this helpful

I take it to support my liver; however, milk thistle is not as effective as silybin, which I am using here. After two months, the results are evident. I experience no morning heaviness, and my face feels tighter with a noticeably improved colour.

Autoimmune Disorder details

Silybin shows promise for autoimmune disorders

Moderately Effective

Based on 9 Researches

Yang HL, Shi XW. Silybin Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Dendritic Cell Activation and Th17 Cell Differentiation. Front Neurol. 2021;12:659678. doi:10.3389/fneur.2021.659678

We investigated how silybin, a unique flavonoid found in certain plants, impacts autoimmune disorders, specifically using a model for multiple sclerosis called experimental autoimmune encephalomyelitis (EAE).

In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.

The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.

Alleviates discomfort

Most Useful Review

1 people found this helpful

I adore Milk Thistle. I experienced bile issues and discomfort but after a week of taking it, all symptoms vanished. I can take it continuously without interruption, so I highly recommend it. I even ordered some for my mother.

Updated: Mar 2026

Acne details

Silybum marianum reduces acne severity

Moderately Effective

Based on 3 Researches

Fontao F, von Engelbrechten M, Seilaz C, Sorg O, Saurat JH. Microcomedones in non-lesional acne prone skin New orientations on comedogenesis and its prevention. J Eur Acad Dermatol Venereol. 2020;34:357. doi:10.1111/jdv.15926

We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.

Strong efficacy noted

Most Useful Review

4 people found this helpful

I will buy again! Having used milk thistle previously with satisfaction, I initially faced breakouts, and my back and chest also became affected. My landlord suggested I try milk thistle for liver support, and it worked wonders! I've now tried this version and will definitely keep using it regularly. My skin appears better, although I do have acne-prone skin.

Updated: Apr 2026

Constipation details

Relieves constipation

Very effective for constipation and gas relief. I also noticed lighter and clearer skin due to its liver-purifying properties.

I liked this drug! In winter, I had a tendency to get chills, and horrible inflammation used to appear. Adding Milk Thistle to my regimen has made a substantial difference. This winter, I noticed no rashes or painful spots, which is a significant improvement.

Common Cold details

Liver Disease details

Silymarin improves liver protection

Possibly Effective

Based on 16 Researches

Okiljević B, Martić N, Govedarica S, Andrejić Višnjić B, Bosanac M, et al. Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress. Pharmaceutics. 2024;16. doi:10.3390/pharmaceutics16040520

We investigated the effects of silymarin on liver and heart health under oxidative stress from paracetamol. In a controlled study with 28 male mice, silymarin showed a strong potential to reduce liver injury markers and improve liver enzyme levels after treatment.

Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.

Liver support effectiveness

Most Useful Review

136 people found this helpful

The ingredients are excellent. Milk thistle is beneficial for liver health, especially regarding liver disease.

Updated: Mar 2026

Chronic Fatigue Syndrome details

Reduced fatigue feeling

1 people found this helpful

I find that my fatigue has diminished since adding Milk Thistle to my routine. The capsules are small and easy to swallow, making them a convenient addition to my continuous struggle against chronic fatigue syndrome.