Last update
3/28/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 11 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Milk Thistle Seed 30:1 Extract(Silybum marianum) (Fruit/Seed) (80% [120 mg] Total Flavonoids)
150 mg
†
Top Medical Research Studies
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
Most Useful Reviews
8
Liver cleansing benefits
338 people found this helpful
Milk thistle is the most valuable product for healing liver cells and the entire organism. It cleanses blood vessels and removes toxins from the body. This fibre activates the bowels and aids in dysbacteriosis, hemorrhoids, hepatitis, and varicose veins. I take it in courses for 2-3 months every half a year and feel much better with it. A favourable dosage and quantity.
Read More
8
Accelerates recovery
4 people found this helpful
I took milk thistle oil for my wife to help the liver recover after hepatitis. Its benefits stem from silymarin, which accelerates cell regeneration. We took two capsules daily, and it significantly aided her recovery.
Read More
9
Effective recovery aid
3 people found this helpful
This has been the only effective solution for recovering from non-viral hepatitis. It was the only thing that my body could utilise without upsetting my stomach. Day by day, my liver grew stronger, and that awful yellow skin colour faded away.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
- All Researches
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
8
Liver cleansing benefits
338 people found this helpful
Milk thistle is the most valuable product for healing liver cells and the entire organism. It cleanses blood vessels and removes toxins from the body. This fibre activates the bowels and aids in dysbacteriosis, hemorrhoids, hepatitis, and varicose veins. I take it in courses for 2-3 months every half a year and feel much better with it. A favourable dosage and quantity.
Read More
8
Accelerates recovery
4 people found this helpful
I took milk thistle oil for my wife to help the liver recover after hepatitis. Its benefits stem from silymarin, which accelerates cell regeneration. We took two capsules daily, and it significantly aided her recovery.
Read More
9
Effective recovery aid
3 people found this helpful
This has been the only effective solution for recovering from non-viral hepatitis. It was the only thing that my body could utilise without upsetting my stomach. Day by day, my liver grew stronger, and that awful yellow skin colour faded away.
Read More
9
Normalized liver profile
3 people found this helpful
As a diabetic, I learned the importance of liver health after experiencing issues resembling hepatitis. Milk thistle effectively restored my liver profile to normal after I started taking it about 12 years ago.
Read More
8
Stable test results
1 people found this helpful
Long-term consumption of milk thistle prevents hepatitis. After two months, my latest test results remain stable. It's a cost-effective purchase at a reduced price.
Read More
Frequently Asked Questions
8
Excellent for liver function
This is one of the best milk thistles available! For those with impaired liver function, taking three tablets a day produced excellent results within a month. I highly recommend this milk thistle for anyone with liver disease, including hepatitis.
7
Provides relief
It has benefits; I have hepatitis B and after one bottle, I feel relief in my liver. I will continue taking this supplement.
9
Normalized liver profile
3 people found this helpful
As a diabetic, I learned the importance of liver health after experiencing issues resembling hepatitis. Milk thistle effectively restored my liver profile to normal after I started taking it about 12 years ago.
9
Effective recovery aid
3 people found this helpful
This has been the only effective solution for recovering from non-viral hepatitis. It was the only thing that my body could utilise without upsetting my stomach. Day by day, my liver grew stronger, and that awful yellow skin colour faded away.
10
Cured chronic hepatitis
Milk thistle is the holy medicine for my liver. My chronic hepatitis was successfully treated by combining milk thistle and artichoke. The quality of this brand is excellent, and I plan to stock up when on sale!
References
- Payer BA, Reiberger T, Rutter K, Beinhardt S, Staettermayer AF, et al. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Clin Virol. 2010;49:131. 10.1016/j.jcv.2010.07.006
- Polyak SJ, Morishima C, Lohmann V, Pal S, Lee DY, et al. Identification of hepatoprotective flavonolignans from silymarin. Proc Natl Acad Sci U S A. 2010;107:5995. 10.1073/pnas.0914009107
- Seeff LB, Curto TM, Szabo G, Everson GT, Bonkovsky HL, et al. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47:605. PubMed
