Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%

The product is found useful for the following medical conditions

Knee Pain details

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Good
Based on 15 Reviews
8.7
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
9
Alleviated knee pain
Most Useful Review
17 people found this helpful
I started taking magnesium to combat my back pain and was pleasantly surprised to find my knee pain improved as well. It's remarkable how quickly the pain alleviated, though skipping doses does bring back the discomfort!

Bacterial Infection details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
10
Bacterial infection prevention
Most Useful Review
I absolutely adore it! I've been using it for years and have not caught a single cold or infection. I highly recommend it.

Vertigo details

SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.

After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.

Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.
10
Significant relief
Most Useful Review
This has been a lifesaver for me. Since starting this product, my vertigo has significantly improved, and the issues related to my Ménière’s Disease, such as balance problems and ear ringing, have disappeared. I intend to continue, as it has helped me greatly.

Chronic Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Effective supplement
Most Useful Review
6 people found this helpful
This magnesium supplement is effective for my chronic condition following a kidney injury, resulting in a magnesium deficiency. It's one of the few formulations that significantly impacts my lab reports. I recommend taking it in the evening as it helps relax my skeletal muscles and aids sleep.

Depression details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 18 Reviews
8.5
We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.

Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
9
Improved well-being
Most Useful Review
312 people found this helpful
I had been experiencing constant sleepiness, headaches, irritability, and depression before starting magnesium. Using Magnesium Caps has helped me assimilate essential vitamins and minerals, thin my blood, and synthesise the hormone of joy. It effectively alleviated insomnia and my migraines, apathy and depression have vanished. I now feel refreshed after six hours of sleep and my mental clarity has improved significantly. I highly recommend it, especially when taken before bedtime!

Hemorrhoids details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Effective treatment
Most Useful Review
6 people found this helpful
Alhamdulillah, it's been a while since I started using this product, and I want to share my thoughts. It is very effective and works swiftly. I have suffered from hemorrhoids for quite some time since giving birth, but this product has helped me immensely. I feel healthy again; there’s no pain when I defecate or eat spicy foods. The itching and pain have significantly reduced, and I believe my hemorrhoids are now 80% better. The quality and various benefits of this product are exceptional.

Hypothyroidism details

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 5 Reviews
8.4
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.

In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.

However, no noteworthy changes were observed in the control group regarding thyroid hormones.

Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
9
Effective supplement
Most Useful Review
After being diagnosed with hypothyroidism and trying hormonal therapy with no improvement, I decided to try magnesium. I've been taking it for less than a week, and I already feel better—no more freezing limbs or constipation. This supplement genuinely works!

Tinnitus details

SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.

By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.

Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
9
Resolved dizziness
Most Useful Review
I bought magnesium as I was feeling dizzy and dealing with tinnitus, and it worked effectively.

Anxiety details

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.9
USERS' SCORE
Good
Based on 49 Reviews
8.3
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.

We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.

Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.

In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
9
Supports anxiety relief
Most Useful Review
204 people found this helpful
My favourite magnesium supplement has a high dosage of 500 mg per capsule. It effectively supports my nervous system, combats anxiety, helps with muscle cramps, and stabilises sleep. I take one capsule each evening a few hours before bed. The packaging lasts me 3.5 months, and I’m very satisfied with the quality and dosage. There are three forms of magnesium in the composition, ensuring rapid absorption in my body.

Blurred Vision details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Enhanced vision
Most Useful Review
My condition is improving daily. I’ve noticed a significant enhancement in my skin, hair, and nails, along with better hearing and vision. I am truly grateful for such excellent products and am very pleased with the results.

Celiac details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.3
7.5
Muscle relaxation support
Most Useful Review
This product from Life Extension has enhanced my daily diet. Magnesium is essential for muscle, joint, and nervous system function, and this supplement has met my expectations. The capsule size is convenient, containing 500 mg of magnesium per capsule, especially useful during high stress. I’ve noticed fewer muscle spasms, deeper sleep, and lower stress levels without side effects, which is significant for me. It's suitable for various dietary preferences. Consult a doctor if unsure about magnesium levels.

Common Cold details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.3
7.5
Effective for colds
Most Useful Review
23 people found this helpful
This magnesium is excellent. A cardiologist found an abnormality in my heart, which could be linked to my mother’s vitamin D deficiency during pregnancy. I experienced tachycardia and cramps in my calves. Within a week of taking this supplement, I noticed significant improvement. I prioritised chelated forms due to their higher bioavailability compared to inorganic compounds. This product combines magnesium oxide, citrate, succinate, and lysylglycinate chelate.

Headache details

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 63 Reviews
8.3
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
9
Stops severe headaches
Most Useful Review
315 people found this helpful
Fantastic Magnesium supplement. I opted for this product after extensive research on magnesium supplements online. My previous brand rated poorly on Labdoor.com, but this supplement emerged as their top-ranking magnesium supplement. I have trusted Labdoor for a long time, and this product proved to be excellent; I noticed improvements within a week. It alleviated issues like difficulty sleeping, muscle cramps, slightly elevated blood pressure, and importantly, my severe headaches from occipital neuralgia. Ever since I started taking magnesium several years ago, I haven't experienced a bad headache.

Polycystic Ovary Syndrome details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.3
9
Eased symptoms effectively
Most Useful Review
3 people found this helpful
Magnesium has significantly improved my well-being in just three weeks. I originally purchased it to help with hormone balancing and PCOS. While I've made some lifestyle changes, I believe magnesium has played a major role in how much better I feel. Thank you!

Atrial Flutter details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
Significant improvement
Most Useful Review
7 people found this helpful
The best healthy food selected by Mae! After reviewing many options, I chose this product and have been very satisfied. During my regular examination every two years, the results were notably positive, partly due to the health supplement I’ve been taking. My issues with arrhythmia and palpitations have significantly improved. Please continue providing good products at affordable prices. Thank you!

Back Pain details

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 36 Reviews
8.2
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
9
Alleviated back pain
Most Useful Review
17 people found this helpful
I started taking magnesium for my back pain. After a few days, I noticed a significant reduction in pain, and it almost disappeared when I continued taking it. However, the pain returns if I miss a dose!

Kidney Stones details

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.3
USERS' SCORE
Good
Based on 9 Reviews
8.2
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.

After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.

Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
9
Eases kidney stones
Most Useful Review
6 people found this helpful
This magnesium supplement is effective for my magnesium deficiency due to a chronic kidney condition. I have noticed positive changes in my blood reports. I recommend taking it in the evening, as it relaxes muscles and aids sleep.

Premenstrual Syndrome details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 65 Reviews
8.2
10
Fights PMS pain
Most Useful Review
32 people found this helpful
I can't praise magnesium enough! Since I started taking it, I've experienced significant improvements: I fall asleep quickly, feel less irritable, and my PMS has become much more manageable, with no pains or discomfort. I’ve also noticed fewer headaches and an overall improved mood throughout the day. Moreover, magnesium supports bone health and helps tackle inflammation. It promotes healthy cardiovascular function and encourages beneficial metabolic factors.

Adrenal Gland Disorder details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.1
9
Enhanced sleep quality
Most Useful Review
Magnesium is truly remarkable! I consistently take magnesium, as stress depletes the adrenal glands, impacting sleep, health, and muscle function. This is my family's go-to magnesium, promoting excellent sleep, increasing concentration to 100%, enhancing memory, and eliminating anxiety. I highly recommend regular magnesium intake. The white capsules are easy to swallow, and I’ve noticed no side effects. I hope my review and experience can assist others.

Heart Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 48 Reviews
8.1
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.

In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.

Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
9
Aids heart recovery
Most Useful Review
219 people found this helpful
Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.

Leg Cramps details

SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
USERS' SCORE
Good
Based on 187 Reviews
8.1
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.

Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.

The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
9
Eliminated leg cramps
Most Useful Review
421 people found this helpful
I liked Now Foods magnesium 500 mg. The capsules come in good packaging, with 100 capsules at an acceptable price. Taking one capsule daily eliminated my irritability, helped normalise my sleep, and stopped my leg cramps. This effective supplement improved my mood and condition without side effects.

Migraine details

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Good
Based on 26 Reviews
8.1
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
9
Reduced migraines
Most Useful Review
312 people found this helpful
Using Magnesium Caps has been transformative! Before, I struggled with constant sleepiness, headaches, irritability, and nervousness. This supplement aids in the absorption of vitamins and minerals, effectively thinning the blood and reducing my migraines. It also helped me overcome insomnia and depression. I now wake refreshed after just six hours of sleep. Highly recommended!

Stroke details

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.1
We embarked on an intriguing exploration of how magnesium might help during cerebral ischemia, particularly after an acute stroke. The study set out to determine the potential benefits of a biodegradable neuroprotective stent that releases magnesium into the bloodstream, targeting areas impacted by reperfusion injury.

To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.

Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.

In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.
7.5
Calming effect noted
Most Useful Review
5 people found this helpful
I can feel the calming effect of magnesium, which is vital for normal bone structure. Low levels of magnesium are linked to various diseases, including osteoporosis, high blood pressure, heart disease, diabetes, and stroke. These pills are easy to take, and I felt the calming effects within 30 minutes. I opted for this after my last physical showed slightly elevated LDL levels, and I’ll post my next test results as an update.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 57 Reviews
8
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
9
Improved sleep quality
Most Useful Review
262 people found this helpful
After taking magnesium, I found I became much calmer, my sleep improved, and my legs stopped hurting. Magnesium is crucial for our bodies and is recommended for pregnant women. I take 2 capsules after meals or 30-40 minutes before bedtime. Since using this product, I sleep well, feel less fatigued, and manage my duties as a mother more effectively. I highly recommend it; the quality matches the price, and I appreciate the capsule size.

Diabetes details

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Good
Based on 9 Reviews
8
We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.

However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
9
Diabetes risk reduction
Most Useful Review
1 people found this helpful
Magnesium is a vital mineral involved in numerous biochemical reactions. It helps convert food into energy, synthesise DNA and proteins, and conduct nerve impulses. Without sufficient magnesium, risks of cardiovascular diseases, hypertension, osteoporosis, and type 2 diabetes increase. The dosage is good, lasting for 100 days of usage.

Insomnia details

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 68 Reviews
8
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
9
Fights insomnia effectively
Most Useful Review
312 people found this helpful
Using Magnesium Caps has markedly improved my daily sleepiness, irritability, and headaches. I found that it reduces insomnia, and I no longer experience migraines or apathy. I feel refreshed after a good night’s sleep. I highly recommend it, especially if taken before bedtime!

Osteoporosis details

SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.2
USERS' SCORE
Good
Based on 32 Reviews
8
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.

Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.

In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.

Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
9
Muscle tension relief
Most Useful Review
I trust the quality of this magnesium product, which contains 500mg. It’s easy to consume, and the packaging is convenient. I find it effective in relieving muscle and nerve tension while also aiding in osteoporosis treatment.

Sleep Apnea details

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 70 Reviews
8
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
9
Calmer nights
Most Useful Review
110 people found this helpful
Magnesium helps me achieve restful sleep at night and calms my nervous system effectively.

Adenoiditis details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
9
Very effective product
Most Useful Review
1 people found this helpful
A wonderful product. The capsules are not large, so they don't get stuck in my throat. It works well.

Heart Attack details

SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.8
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
9
Reduces heart issues
Most Useful Review
6 people found this helpful
Life Extension's magnesium supplement is fantastic. It aids in recovery and alleviates stress due to deficiencies. It helps with heart health and lowers blood pressure, enhances energy production, and improves sleep. This supplement also has anti-inflammatory benefits, making it a vital part of my diet.

Bone Pain details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Moderately Good
Based on 75 Reviews
7.7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7.5
No bone pain
Most Useful Review
490 people found this helpful
Working magnesium is excellent. I take one pill in the evening after discovering my magnesium levels were nearly zero. Despite being an emotional person, I've noticed no muscle pain or nerve issues during its use—it's clearly effective!

Cardiovascular Disease details

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
USERS' SCORE
Moderately Good
Based on 38 Reviews
7.7
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
7.5
Eases cardiovascular issues
Most Useful Review
54 people found this helpful
I took magnesium while recovering from COVID-19 to address deficiency, taking 1000 mg daily. I enjoy this product without side effects. It improves cardiovascular function and my nervous system, so I recommend drinking it in cycles for optimal benefits.

High Cholesterol details

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.7
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.

In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.

We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.

This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
9
Cramps alleviated
Most Useful Review
1 people found this helpful
This magnesium is highly dosed and compatible, presented at a great price. I used to suffer from calf cramps at night, but since taking these capsules, they have disappeared entirely.

Frozen Shoulder details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.6
9
Migraine relief
Most Useful Review
8 people found this helpful
After over 10 years of migraines due to atmospheric pressure and my frozen shoulder, I tried magnesium. Surprisingly, after just two days, my migraines vanished. It may not work for everyone, but if you're suffering from headaches, it's worth a shot.

Swollen Lymph Nodes details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.6
10
Pleasant results
Most Useful Review
Excellent! I take a capsule at night. My legs were extremely swollen from standing all day. Now there's no swelling, and I am very pleased with my choice.

Indigestion details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.5
9
Effective for colon issues
Most Useful Review
1 people found this helpful
Wonderful! This is the third time I have ordered it. It has relieved my colon and indigestion, which was a problem I had been suffering from.

Autoimmune Disorder details

SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
USERS' SCORE
Moderately Good
Based on 47 Reviews
7.4
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.

Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
9
Emotional stability
Most Useful Review
215 people found this helpful
I noticed various forms of magnesium in this product, although the manufacturer did not specify their ratios. After a month, I've felt remarkably calmer, observing that the emotional reactions of others no longer affect me as they did before. However, it's essential to consult with a doctor before using it to ensure it's right for your autoimmune disorder.

Chest Pain details

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.1
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.4
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
9
Reduced chest pain
Most Useful Review
44 people found this helpful
I was admitted to hospital at 16 weeks pregnant due to uterine hypertonicity and severe stomach pain, which no one could explain. I visited an osteopath, but after trying various medications, my doctor advised magnesium. I took one tablet daily, and my spasms began to reduce after three days. My bowel movements improved, and I felt much better overall. Now at 23 weeks, I no longer have uterine tension or any worries.

Pelvic Pain details

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Moderately Good
Based on 23 Reviews
7.3
We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.

The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
9
Improved pelvic pain
Most Useful Review
44 people found this helpful
Saved from cramps during pregnancy. At 16 weeks, I was admitted with uterine hypertonicity. The pain continued, and various medications did not help. The doctor advised magnesium, which I took daily. Within three days, my symptoms improved significantly. Now at 23 weeks, I feel great with no more tone or discomfort.

Heartburn details

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.5
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.2
We explored the impact of a new treatment, Marial®, on patients suffering from gastroesophageal reflux disease (GERD). In a large survey involving 56 gastroenterological offices across Italy, patients were treated with either proton pump inhibitors (PPIs), a combination of PPIs and an additional remedy, or the Marial® formulation containing magnesium alginate. The results showed that both Marial® and the combination therapy significantly reduced heartburn symptoms, with Marial® proving to be more effective than the combination. Overall, patients reported a marked improvement in their GERD-related symptoms.
9
Effective heartburn relief
Most Useful Review
Excellent product! I take it at night, and it significantly helps with my heartburn. The magnesium is of high quality, and the package is relatively large.

Constipation details

SCIENTIFIC SCORE
Questionable
Based on 22 Researches
6.8
USERS' SCORE
Moderately Good
Based on 142 Reviews
7.1
We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.

Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.

Importantly, there were no severe treatment-related side effects reported during the trial.
10
Constipation relief
Most Useful Review
21 people found this helpful
I suffered from migraines and initially dismissed magnesium supplements. However, after trying this, my constipation disappeared within two days, and I lost 3 kg. My headaches have reduced significantly, making my days easier. I now recommend it to friends.

Food Poisoning details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.1
We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.
9
Effective for constipation
Most Useful Review
It really helps. I used magnesium citrate as an oral laxative when nothing else worked. My doctor prescribed it after I experienced constipation due to travel and food poisoning. After taking a 10 oz bottle at 4 p.m., I felt the urge to go to the toilet by 10 p.m., which continued until 5 a.m. This product is strong but highly effective.

Athlete’s Foot details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.7
9
Leg cramps alleviated
Most Useful Review
4 people found this helpful
No more leg cramps after switching to a keto lifestyle. I faced severe cramps and constipation, but since I began taking Life Extension magnesium supplements, I've only experienced one episode of cramps at night. Increasing my intake from one to two capsules has effectively resolved the issue.

Irritable Bowel Syndrome details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 55 Reviews
6.5
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.

Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.

Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
9
Regulated bowel transit
Most Useful Review
11 people found this helpful
My wife has irritable bowel syndrome and struggled with constipation. After trying various methods, this supplement has resolved her issues. Previously, she would go four to five days without a bowel movement, but now she goes twice daily. The quality of this magnesium complex is excellent and it's easy to take.
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