Life Extension Magnesium Caps 500 mg

Magnesium oxide treats leg cramps

Likely Ineffective

Based on 16 Researches

A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.

Most Relevant Research

We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.

Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.

The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.

9.5

Eliminated leg cramps

Most Useful Review

I liked Now Foods magnesium 500 mg. The capsules come in good packaging, with 100 capsules at an acceptable price. Taking one capsule daily eliminated my irritability, helped normalise my sleep, and stopped my leg cramps. This effective supplement improved my mood and condition without side effects.

Anxiety

Magnesium treats anxiety in MS

Based on 12 Researches

Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.

Most Relevant Research

We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.

We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.

Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.

In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.

9.5

Supports anxiety relief

Most Useful Review

My favourite magnesium supplement has a high dosage of 500 mg per capsule. It effectively supports my nervous system, combats anxiety, helps with muscle cramps, and stabilises sleep. I take one capsule each evening a few hours before bed. The packaging lasts me 3.5 months, and I’m very satisfied with the quality and dosage. There are three forms of magnesium in the composition, ensuring rapid absorption in my body.

Insomnia

Magnesium improves elderly insomnia

Based on 11 Researches

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.

Most Relevant Research

We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.

9.5

Fights insomnia effectively

Most Useful Review

Using Magnesium Caps has markedly improved my daily sleepiness, irritability, and headaches. I found that it reduces insomnia, and I no longer experience migraines or apathy. I feel refreshed after a good night’s sleep. I highly recommend it, especially if taken before bedtime!

Migraine

Magnesium reduces migraine symptoms

Based on 16 Researches

Magnesium and Migraine.

Most Relevant Research

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.

9.5

Reduced migraines

Most Useful Review

Using Magnesium Caps has been transformative! Before, I struggled with constant sleepiness, headaches, irritability, and nervousness. This supplement aids in the absorption of vitamins and minerals, effectively thinning the blood and reducing my migraines. It also helped me overcome insomnia and depression. I now wake refreshed after just six hours of sleep. Highly recommended!

Back Pain

Magnesium reduces postoperative back pain

Based on 6 Researches

Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.

Most Relevant Research

We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.

9.5

Alleviated back pain

Most Useful Review

I started taking magnesium for my back pain. After a few days, I noticed a significant reduction in pain, and it almost disappeared when I continued taking it. However, the pain returns if I miss a dose!

Cardiovascular Disease

Magnesium's impact on heart health

Based on 8 Researches

The Role of Dietary Magnesium in Cardiovascular Disease.

Most Relevant Research

We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.

8.8

Eases cardiovascular issues

Most Useful Review

I took magnesium while recovering from COVID-19 to address deficiency, taking 1000 mg daily. I enjoy this product without side effects. It improves cardiovascular function and my nervous system, so I recommend drinking it in cycles for optimal benefits.

Heart Disease

Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.

Hypothyroidism

Magnesium shows promise in thyroid recovery

Based on 3 Researches

Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.

Most Relevant Research

We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.

Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.

However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.

9.5

Effective supplement

Most Useful Review

After being diagnosed with hypothyroidism and trying hormonal therapy with no improvement, I decided to try magnesium. I've been taking it for less than a week, and I already feel better—no more freezing limbs or constipation. This supplement genuinely works!

Vertigo

Effective magnesium treatment for vertigo

Likely Very Effective

Based on 3 Researches

Successful treatment of a child with definite Meniere's disease with the migraine regimen.

Most Relevant Research

We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.

After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.

Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.

Significant relief

Most Useful Review

This has been a lifesaver for me. Since starting this product, my vertigo has significantly improved, and the issues related to my Ménière’s Disease, such as balance problems and ear ringing, have disappeared. I intend to continue, as it has helped me greatly.

Bone Pain

Working magnesium is excellent. I take one pill in the evening after discovering my magnesium levels were nearly zero. Despite being an emotional person, I've noticed no muscle pain or nerve issues during its use—it's clearly effective!

Chronic Cough

This magnesium supplement is effective for my chronic condition following a kidney injury, resulting in a magnesium deficiency. It's one of the few formulations that significantly impacts my lab reports. I recommend taking it in the evening as it helps relax my skeletal muscles and aids sleep.

Chronic Fatigue Syndrome

Improved sleep quality

After taking magnesium, I found I became much calmer, my sleep improved, and my legs stopped hurting. Magnesium is crucial for our bodies and is recommended for pregnant women. I take 2 capsules after meals or 30-40 minutes before bedtime. Since using this product, I sleep well, feel less fatigued, and manage my duties as a mother more effectively. I highly recommend it; the quality matches the price, and I appreciate the capsule size.

Common Cold

This magnesium is excellent. A cardiologist found an abnormality in my heart, which could be linked to my mother’s vitamin D deficiency during pregnancy. I experienced tachycardia and cramps in my calves. Within a week of taking this supplement, I noticed significant improvement. I prioritised chelated forms due to their higher bioavailability compared to inorganic compounds. This product combines magnesium oxide, citrate, succinate, and lysylglycinate chelate.

Gout

Magnesium may protect against bone erosion

Based on 2 Researches

Serum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study.

Most Relevant Research

We examined the relationship between magnesium levels and the occurrence of bone erosion in patients with gouty arthritis. In our analysis, we observed that 769 gout patients were studied, allowing us to classify them into groups based on their serum ionized magnesium levels.

The results were striking: those with lower magnesium levels had a significantly higher rate of bone erosion. Specifically, patients in the lowest magnesium group showed a bone erosion prevalence rate of over 60%, compared to less than 45% in those with higher magnesium levels.

Our findings suggest that maintaining adequate levels of magnesium might offer a protective effect against bone deterioration in gout arthritis. This points to the possibility that magnesium supplementation could be beneficial for preventing or slowing down bone erosion in these patients.

9.5

Gout symptoms relief

Most Useful Review

The best supplement for reducing uric acid. After 1-2 weeks, my gout symptoms vanished. Uric acid levels decrease quite slowly, but the pain disappears!

Urinary Tract Infection

Cramps relief achieved

Saved from cramps during pregnancy. At 16 weeks, I was admitted to hospital with uterine hypertonicity. The sharp stomach pain persisted post-hospital, and numerous medications didn’t help. The doctor advised taking magnesium, which I followed, and ultimately, it worked. In three days, my spasms receded, and my condition improved significantly. I’m now 23 weeks along and feeling very well, with no more tone problems or discomfort.

Kidney Stones

Magnesium reduces kidney stone risk

Based on 8 Researches

Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.

Most Relevant Research

We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.

After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.

Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.

9.5

Eases kidney stones

Most Useful Review

This magnesium supplement is effective for my magnesium deficiency due to a chronic kidney condition. I have noticed positive changes in my blood reports. I recommend taking it in the evening, as it relaxes muscles and aids sleep.

Pneumonia

Strengthened immune system

I recommend taking magnesium after treating pneumonia caused by Covid, along with B vitamins from the same company. After three weeks, I'm pleased with the results—my body feels stronger, anxiety and nervousness have diminished, and my heartbeat has stabilised. Magnesium is well absorbed.

Tinnitus

Magnesium's role in tinnitus explored

Based on 6 Researches

Relationship between serum magnesium level and subjective tinnitus.

Most Relevant Research

We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.

By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.

Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.

9.5

Resolved dizziness

Most Useful Review

I bought magnesium as I was feeling dizzy and dealing with tinnitus, and it worked effectively.

Cancer

Magnesium alloy inhibits cancer growth

Based on 5 Researches

Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer.

Most Relevant Research

We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments.

In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.

Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.

With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.

8.8

Better digestive health

Most Useful Review

I have battled breast cancer, and my oncologist recommended magnesium for better function. After over 20 years of taking it, I sought a new brand due to unavailability of my former one. The positive reviews encouraged me to try this one. So far, it has been great.

Dizziness

Magnesium's role in Meniere's treatment

Based on 6 Researches

Successful treatment of a child with definite Meniere's disease with the migraine regimen.

Most Relevant Research

We observed the intriguing connection between Meniere's disease (MD) and migraine-related dizziness in our study of a 5-year-old girl. She experienced a six-month struggle with left-sided hearing loss, which evolved into daily bouts of vertigo, headaches, and vomiting, fulfilling the criteria for definite MD.

After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.

This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.

Headaches alleviated

Most Useful Review

I purchased this for headaches and noticed significant improvement while taking it, even when I unknowingly combined it with an antibiotic that caused nausea and dizziness. I've realised my headaches tend to flare up due to excessive caffeine, prompting me to be more cautious. The delivery was prompt, and I find the pills easy to swallow. Thankfully, I've experienced no side effects.

Neuropathy

Magnesium's potential in neuropathy treatment

Based on 7 Researches

Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models.

Most Relevant Research

A recent study explored the connection between magnesium levels and diabetic sensorimotor polyneuropathy. We measured serum magnesium and plasma methylglyoxal levels in recently diagnosed type 2 diabetes patients—some with neuropathy and others without.

Our findings revealed that patients with neuropathy had significantly lower magnesium levels, which were inversely related to higher methylglyoxal levels. This interaction appeared to contribute to nerve dysfunction, making magnesium's role particularly interesting in the context of neuropathy.

We found that magnesium supplementation could protect nerve cells from the neurotoxic effects of methylglyoxal in laboratory models. Importantly, when magnesium was added, we observed improvements in cell health, suggesting that maintaining magnesium levels might be a promising strategy for mitigating diabetic neuropathy.

Overall, our research highlights a compelling link between magnesium deficiency and nerve damage, suggesting that addressing magnesium levels could hold the key to new treatment approaches for diabetic neuropathy and possibly other neurodegenerative conditions.

8.8

Cramps alleviated

Most Useful Review

I suffer from severe leg cramps and began using magnesium to treat it. Initially, it worked wonders; however, after running out, the pain returned fiercely. After reordering, my leg cramps disappeared. Given that many people are deficient in magnesium, I encourage supplementation, as it is difficult to obtain enough through diet alone, especially with today’s nutrient-poor food sources. I also use magnesium to manage my peripheral neuropathy and highly recommend this brand for its efficacy.

Stroke

Magnesium shows neuroprotective promise

Based on 15 Researches

Neuroprotection on ischemic brain injury by Mg/H released from endovascular Mg implant.

Most Relevant Research

We embarked on an intriguing exploration of how magnesium might help during cerebral ischemia, particularly after an acute stroke. The study set out to determine the potential benefits of a biodegradable neuroprotective stent that releases magnesium into the bloodstream, targeting areas impacted by reperfusion injury.

To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.

Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.

In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.

7.5

Calming effect noted

Most Useful Review

I can feel the calming effect of magnesium, which is vital for normal bone structure. Low levels of magnesium are linked to various diseases, including osteoporosis, high blood pressure, heart disease, diabetes, and stroke. These pills are easy to take, and I felt the calming effects within 30 minutes. I opted for this after my last physical showed slightly elevated LDL levels, and I’ll post my next test results as an update.

Autoimmune Disorder

I noticed various forms of magnesium in this product, although the manufacturer did not specify their ratios. After a month, I've felt remarkably calmer, observing that the emotional reactions of others no longer affect me as they did before. However, it's essential to consult with a doctor before using it to ensure it's right for your autoimmune disorder.

Diabetes

Magnesium deficiency affects diabetes control

Based on 7 Researches

Hypomagnesemia in adults with type 2 diabetes mellitus in Riyadh, Saudi Arabia: A cross-sectional study.

Most Relevant Research

We looked into how magnesium levels relate to diabetes, specifically focusing on adults with type 2 diabetes mellitus (T2DM) in Riyadh, Saudi Arabia. Conducted as a cross-sectional study, we analyzed data from 294 individuals, including T2DM patients, prediabetics, and nondiabetic controls. Our goal was to uncover the prevalence of magnesium deficiency and its potential effects on various metabolic factors.

The findings revealed a striking difference in magnesium levels across the groups. T2DM patients exhibited notably lower magnesium than those with prediabetes and nondiabetic controls. This deficiency was linked to worse metabolic outcomes, including higher fasting glucose and glycated hemoglobin (HbA1c) levels, as well as increased insulin resistance.

We noted a strong negative correlation between magnesium levels and both glucose and HbA1c, suggesting that as magnesium levels decrease, diabetes control worsens. Interestingly, our analysis indicated that magnesium levels could effectively predict higher HbA1c values, highlighting the need for regular monitoring of magnesium in diabetes management.

While our study emphasizes the significant impact of magnesium deficiency on the metabolic health of T2DM patients, it also opens the door for further exploration regarding the benefits of magnesium supplementation in diabetes care. Overall, these insights push us to consider the broader implications of maintaining proper magnesium levels for better diabetes management.

9.5

Diabetes risk reduction

Most Useful Review

Magnesium is a vital mineral involved in numerous biochemical reactions. It helps convert food into energy, synthesise DNA and proteins, and conduct nerve impulses. Without sufficient magnesium, risks of cardiovascular diseases, hypertension, osteoporosis, and type 2 diabetes increase. The dosage is good, lasting for 100 days of usage.

Heart Attack

Magnesium implantation improves heart recovery

Based on 14 Researches

Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.

Most Relevant Research

We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.

9.5

Reduces heart issues

Most Useful Review

Life Extension's magnesium supplement is fantastic. It aids in recovery and alleviates stress due to deficiencies. It helps with heart health and lowers blood pressure, enhances energy production, and improves sleep. This supplement also has anti-inflammatory benefits, making it a vital part of my diet.

Frozen Shoulder

After over 10 years of migraines due to atmospheric pressure and my frozen shoulder, I tried magnesium. Surprisingly, after just two days, my migraines vanished. It may not work for everyone, but if you're suffering from headaches, it's worth a shot.

Sleep Apnea

Magnesium's role in sleep apnea

Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.

Most Relevant Research

We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.

8.3

Calmer nights

Most Useful Review

Magnesium helps me achieve restful sleep at night and calms my nervous system effectively.

Bloating

Magnesium alleviates menstrual bloating

Based on 5 Researches

Magnesium supplementation alleviates premenstrual symptoms of fluid retention.

Most Relevant Research

We explored the impact of magnesium supplementation on bloating as part of a larger study examining premenstrual symptoms. In our randomized, double-blind, placebo-controlled design, we administered a daily dose of 200 mg of magnesium (as MgO) to participants over the course of two menstrual cycles. Each volunteer kept track of their symptoms using a detailed diary with twenty-two items.

Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.

Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.

2.5

Terrible digestive issues.

Most Useful Review

I've taken magnesium for years without issues but had a bad reaction to this new brand, experiencing terrible bloating and gas after just a few days. I've confirmed that this supplement does not agree with me as the symptoms disappeared when I stopped taking it. I can’t return it, so I may attempt to adjust the dosage by making my own.

Chest Pain

Magnesium supplementation aids chest pain

Based on 5 Researches

The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy.

Most Relevant Research

We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.

9.5

Reduced chest pain

Most Useful Review

I was admitted to hospital at 16 weeks pregnant due to uterine hypertonicity and severe stomach pain, which no one could explain. I visited an osteopath, but after trying various medications, my doctor advised magnesium. I took one tablet daily, and my spasms began to reduce after three days. My bowel movements improved, and I felt much better overall. Now at 23 weeks, I no longer have uterine tension or any worries.

Ear Infection

Magnesium possesses essential benefits for sleep and muscles. However, after using this product, my family and I developed urinary tract infections. The quality is lovely, but the side effects were concerning.

Colitis

Magnesium's effect on colitis

Based on 7 Researches

Improvement of magnesium isoglycyrrhizinate on DSS-induced acute and chronic colitis.

Most Relevant Research

We investigated the potential benefits of magnesium isoglycyrrhizinate in treating colitis induced by dextran sulfate sodium (DSS). Our findings suggest that magnesium isoglycyrrhizinate can effectively alleviate both acute and chronic symptoms of colitis.

The treatment helped reduce inflammation by lowering the number of immune cells in the affected areas and decreasing levels of inflammatory cytokines. Additionally, we noted it significantly reduced reactive oxygen species (ROS) levels and mitigated the damage to the gut barrier associated with DSS treatment.

Another key observation was the treatment's ability to decrease colonic fibrosis, a common complication of IBD. Overall, these results indicate that magnesium isoglycyrrhizinate shows promise in managing intestinal inflammation and could be beneficial for people suffering from inflammatory bowel disease in clinical settings.

1.3

Not suitable for colitis

Most Useful Review

Avoid this if you have colitis. Fellow sufferers of pseudomembranous colitis, unless you seek uncontrollable diarrhoea alongside your usual issues, this product is not for you. Instead, I recommend magnesium glycinate, as this disease impairs magnesium absorption. This supplement is not suitable for us. I don't hold the manufacturer responsible, but they should have listed this common side effect.

Constipation

Effectiveness of magnesium on constipation

Based on 11 Researches

Effect of reduced daily magnesium oxide doses on laxative effect: a single-center retrospective study.

Most Relevant Research

We explored how changing the frequency of magnesium oxide (MgO) doses influences its effectiveness in relieving constipation. In this study, we looked at 11 patients who had been regularly using MgO to manage their bowel movements and decided to reduce their daily dose frequency over two weeks.

Initially, patients were taking magnesium three times a day, but we reduced this to either two or one dose per day while keeping the total amount the same. We found that the average number of bowel movements dropped from 7.6 to 6.6 in this period. However, this change wasn't statistically significant, indicating that it may not be clinically meaningful.

Additionally, we measured stool consistency using the Bristol Stool Form Scale and noted no significant difference before and after the dosage adjustment. Our findings suggest that reducing the number of doses does not impact the laxative effect of magnesium oxide. This implies that patients can comfortably manage their magnesium intake without sacrificing effectiveness.

Constipation relief

Most Useful Review

I suffered from migraines and initially dismissed magnesium supplements. However, after trying this, my constipation disappeared within two days, and I lost 3 kg. My headaches have reduced significantly, making my days easier. I now recommend it to friends.

Food Poisoning

Effective for constipation