NOW Supplements Magnesium

Magnesium reduces kidney stone risk

Based on 9 Researches

Taheri M, Jalali S, Borumandnia N, Tavasoli S, Basiri A, et al. Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial. Magnes Res. 2024;37:12. doi:10.1684/mrh.2024.0524

We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.

After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.

Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.

Kidney health improvement

Most Useful Review

I spent a long time searching for the right magnesium for my kidney health and found it with this product. I've tried various types over the years, and after learning of my weak kidney, I discovered magnesium oxide online. This supplement from NOW contains 400 mg of magnesium oxide, citrate, and aspartate, and I'm now very satisfied.

Flu details

Magnesium essential for immune response

Kanellopoulou C, George AB, Masutani E, Cannons JL, Ravell JC, et al. Mg regulation of kinase signaling and immune function. J Exp Med. 2019;216:1828. doi:10.1084/jem.20181970

We explored how magnesium affects our immune response, particularly in relation to fighting off influenza. By examining how magnesium levels influence T cell function, we noticed that lower levels of magnesium in the body could hinder the T cell receptor (TCR) activation process. This is significant because TCR activation is crucial for mounting an effective immune response against viruses like influenza.

Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.

Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.

Improved sleep quality

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8 people found this helpful

Healthy vitamins and excellent sleep! Magnesium acts as a natural anti-stress factor, reducing sensitivity to external influences and inhibiting excitation processes in the central nervous system. Insufficient magnesium can lead to anxiety, insomnia, and fatigue. People often experience "causeless" headaches. Magnesium, especially when paired with vitamin B6, normalises the nervous system during stress and depression. I took NOW Magnesium with Vitamin B6 nightly to alleviate stress, irritability, and improve sleep. The effects were noticeable; my sleep and nerves improved significantly! I advise against taking it on an empty stomach. Remarkably, my eye puffiness decreased in the morning!

Headache details

Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725

Magnesium aids migraine management

We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.

Fewer headaches

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199 people found this helpful

I used to suffer from frequent headaches several times a week. After taking this supplement for two months, they have significantly decreased. I will purchase more!

Hemorrhoids details

Reduced hemorrhoids effect

10 people found this helpful

Excellent! I took the metal with my eyes closed. Potassium and magnesium are essential minerals known for muscle relaxation and overall body wellness, which helps reduce anxiety. My experience was lovely from the start; my sleep improved, and my nerves calmed significantly. Initially, I struggled with disturbances, yet I've noticed a transformation in my disposition; I'm much calmer now. I plan to continue taking this mineral, as I observed an effect within just two weeks. It's crucial for absorption, and without it, vitamins would be less effective. It has helped me with chronic constipation, particularly during pregnancy, and remarkably, my hemorrhoids have significantly diminished. My husband noticed a change in me as well. Although I'm unsure of the connection between my other ailments and magnesium, I've become an advocate for its benefits.

Hypothyroidism details

Rabbani E, Golgiri F, Janani L, Moradi N, Fallah S, et al. Randomized Study of the Effects of Zinc, Vitamin A, and Magnesium Co-supplementation on Thyroid Function, Oxidative Stress, and hs-CRP in Patients with Hypothyroidism. Biol Trace Elem Res. 2021;199:4074. doi:10.1007/s12011-020-02548-3

Based on 5 Researches

Magnesium shows potential benefits

We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.

In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.

However, no noteworthy changes were observed in the control group regarding thyroid hormones.

Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.

Improved thyroid function

Most Useful Review

I suffer from hypothyroidism and know magnesium is vital for thyroid function, converting inactive T4 to active T3. I take one capsule of magnesium glycinate nightly and have noticed my leg cramps are gone. It's important to ensure adequate intake, particularly for those with hypothyroidism, and I'm grateful for its benefits when combined with other vitamins.

Menopause details

Magnesium aids menopause-related issues

Based on 8 Researches

Zhang J, Mai CL, Xiong Y, Lin ZJ, Jie YT, et al. The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice. J Inflamm Res. 2021;14:6633. doi:10.2147/JIR.S330894

We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.

We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.

Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.

In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.

Relief from palpitations

Most Useful Review

Amazing! I experience no heartburn from this and feel relaxed immediately when I take it at night. It helps me with menopause palpitations. Thank you so much! Also, great value for money.

Tendonitis details

Pain relief effective

2 people found this helpful

I can't live without this magnesium, and several family members use it too. I suffered pain in my left foot, making it difficult to step, which disturbed my nights. After researching, I discovered it was inflammation of the covering of the bone; it doesn't show on X-rays, only in tomography. I began taking Magnesium Dimalate, and within a week, the pain disappeared. A friend with a similar issue also resolved her problem with it. This product is very helpful for muscle pain, fibromyalgia, and tendonitis.

Vertigo details

Effective magnesium treatment for vertigo

Likely Very Effective

Based on 3 Researches

Abouzari M, Abiri A, Djalilian HR. Successful treatment of a child with definite Meniere's disease with the migraine regimen. Am J Otolaryngol. 2019;40:440. doi:10.1016/j.amjoto.2019.02.004

We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.

After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.

Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.

Reduced eye twitches

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4 people found this helpful

Magnificent magnesium at a great price! I take it alongside vitamin B6 (100 mg) for a month, then have a break. Remarkably, I noticed my eye twitching ceased by the fifth day! I had suffered for 2-3 months before starting this. The price is much lower than at local pharmacies, and it’s sufficient for the whole family. A vital supplement for the body.

Athlete’s Foot details

2 people found this helpful

I cannot live without this magnesium, and several family members use it too. I had pain in my left foot that made stepping difficult, especially at night. After researching, I realised it was inflammation of the tissue covering the bone. I started taking Magnesium Dimalate and within a week, the pain vanished. My friend had the same issue and found relief as well. It is very helpful for muscle pain, athlete’s foot, fibromyalgia, and tendonitis.

Knee Pain details

Magnesium sulfate alleviates postoperative pain

Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. doi:10.1186/s13018-023-03790-w

We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.

Pain relief

Most Useful Review

6 people found this helpful

It didn't run out of magnesium, and it helped alleviate my knee pain significantly. I appreciated that one capsule meets my daily needs. Excellent brand. Thank you, iHerb, for the fast delivery to Rio de Janeiro; it arrived in just 10 days.

Stroke details

Magnesium shows neuroprotective promise

Based on 15 Researches

Zhang Y, Zhang H, Jiang M, Cao X, Ge X, et al. Neuroprotection on ischemic brain injury by Mg/H released from endovascular Mg implant. Bioact Mater. 2024;42:124. doi:10.1016/j.bioactmat.2024.08.019

We embarked on an intriguing exploration of how magnesium might help during cerebral ischemia, particularly after an acute stroke. The study set out to determine the potential benefits of a biodegradable neuroprotective stent that releases magnesium into the bloodstream, targeting areas impacted by reperfusion injury.

To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.

Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.

In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.

7.5

Improved weakness

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2 people found this helpful

Taking magnesium significantly improved my weakness and low pulse, which had dropped to 40 strokes and below. Just two weeks after starting this medication, I noticed a remarkable change. I now take it regularly and have almost forgotten about my previous issues with low pulse and fatigue.

Arthritis details

Magnesium protects against bone erosion

Based on 17 Researches

Li Y, Wang Y, Xu L, Liu C, Cui J, et al. Serum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. Front Endocrinol (Lausanne). 2024;15:1375871. doi:10.3389/fendo.2024.1375871

We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.

Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.

Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.

Pain disappearance

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4 people found this helpful

Magnesium supplementation is essential! It supports the nervous system, cardiovascular system, and cartilage system. For those with joint pain, this is a miracle supplement. My aunt suffers from osteoarthritis, but after taking magnesium daily, her pain has disappeared. I highly recommend it!

Back Pain details

Magnesium reduces postoperative back pain

Based on 7 Researches

Celenlioglu AE, Sir E, Ors-Yildirim N, Yildirim AK, Ince ME, et al. Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting. J Vasc Surg Venous Lymphat Disord. 2023;11:517. doi:10.1016/j.jvsv.2022.09.008

We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.

Pain relief noted

Most Useful Review

139 people found this helpful

The effect is noticeable from the very first capsule! I have a neurological disability and take magnesium regularly. This magnesium is excellent for alleviating spasticity, promoting sleep, and is perfect for irritable bowel syndrome as it quickly eases abdominal pain. I am very pleased with the purchase and will order more.

Bone Pain details

CMT shows potential for pain relief

Based on 3 Researches

Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.

We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.

Muscle pain relief

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230 people found this helpful

Good magnesium; I take it regularly. My muscle pain has disappeared.

We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.

We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.

These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.

Indispensable mineral

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1 people found this helpful

Magnesium is indispensable for managing hypertension. NOW Foods provides an excellent option without equal.

Adenoiditis details

5 people found this helpful

Calmness, only calmness. Six months ago, I sought help from a nutritionist and then from a D-Doctor, who focuses on eliminating vitamin and mineral deficiencies. I suspected iron deficiency, but tests revealed a very low level of magnesium. Symptoms included insomnia, cramps, and irritability. I experienced sudden convulsions at night and felt a lump in my throat. After a thorough examination, the D-Doctor confirmed magnesium deficiency. Previously, I used to rush around when my child was upset, but now I maintain calmness, engaging with my child without raising my voice. This change has brought happiness to both of us.

Anxiety details

Li Z, Chen K, Shao Q, Lu H, Zhang X, et al. Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. J Neuroinflammation. 2023;20:16. doi:10.1186/s12974-023-02696-y

Magnesium treats anxiety in MS

We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.

We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.

Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.

In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.

Reduced anxiety

Most Useful Review

194 people found this helpful

Taking magnesium improved my overall health and significantly reduced my muscle cramps and eyelid twitches. I no longer suffer from anxiety, and my general well-being has enhanced. If you find this review helpful, please like it!

Atrial Flutter details

41 people found this helpful

Calmness, balance, sleep - that's what I experience. I can't speak for others, but it aids me in managing overwork, calming my nerves. Before I began this, I had dull skin, brittle hair and nails, headaches, distractibility, irritability, fatigue, sleep issues, pressure fluctuations, and arrhythmia. I take about 800 mg in two doses. Alongside the subtle, yet significant work magnesium does within my body, I cherish its ability to bring balance.

Blood Clot details

Magnesium scaffold shows promising results

Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study. EuroIntervention. 2023;19:e414. doi:10.4244/EIJ-D-23-00326

We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.

Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.

Overall, our findings support its potential use in heart treatments.

Improved digestion

Most Useful Review

1 people found this helpful

My digestion was slow with significant constipation due to age and medication. After taking magnesium for 8 months, I experienced no constipation and improved digestion. An added benefit was that a blood test showed my cholesterol had increased good levels and decreased bad levels, bringing me within acceptable limits.

Dizziness details

Magnesium's role in Meniere's treatment

Based on 7 Researches

Abouzari M, Abiri A, Djalilian HR. Successful treatment of a child with definite Meniere's disease with the migraine regimen. Am J Otolaryngol. 2019;40:440. doi:10.1016/j.amjoto.2019.02.004

We observed the intriguing connection between Meniere's disease (MD) and migraine-related dizziness in our study of a 5-year-old girl. She experienced a six-month struggle with left-sided hearing loss, which evolved into daily bouts of vertigo, headaches, and vomiting, fulfilling the criteria for definite MD.

After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.

This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.

Reduces dizziness stress

Most Useful Review

Small capsules that are easy to swallow; a large package offers great value. I recommend it due to its quality and effectiveness. It alleviates dizziness and reduces stress responses, improving my overall quality of life. It's now a staple in my meals.

High Cholesterol details

Magnesium chloride reduces liver stress

Based on 9 Researches

Mohammed KA, Goji ADT, Tanko Y, Muhammed A, Salisu IA. Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats. Niger J Physiol Sci. 2019;34:149.

We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.

In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.

We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.

This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.

7.5

Lowers blood pressure

Most Useful Review

1 people found this helpful

Reduces high blood pressure, relaxing my heart and muscles.

Insomnia details

Magnesium improves elderly insomnia

Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.

We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.

7.5

Reduced insomnia symptoms

Most Useful Review

253 people found this helpful

This magnesium is excellent for its price. As a doctor, I recommend it for insomnia and sweet cravings. I noticed improvements in sleep and reduced anxiety after just one dose. My sweet cravings vanished within a week. The capsules are large yet easy to swallow. Given today’s pace of life, magnesium is essential. I will definitely order more for my family.

Osteoporosis details

Magnesium's role in osteoporosis therapy

Based on 19 Researches

Li J, Chen Y, Zha D, Wu C, Li X, et al. Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism. Lipids Health Dis. 2024;23:88. doi:10.1186/s12944-024-02083-3

We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.

Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.

In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.

Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.

Helps with osteoporosis

Most Useful Review

1 people found this helpful

Magnesium helps alleviate insomnia, muscle cramps, and anxiety, and it’s essential for calcium absorption, which aids in preventing osteoporosis. I take a pill before bed and found my body adjusted well to it after initial relaxation effects.

Diabetes details

Magnesium intake benefits diabetes patients

Based on 19 Researches

Huang R, Kong X, Geng R, Wu J, Li J, et al. Associations of dietary magnesium intake with the risk of atherosclerotic cardiovascular disease and mortality in individuals with and without type 2 diabetes: A prospective study in the UK Biobank. Diabetes Metab. 2024;50:101554. doi:10.1016/j.diabet.2024.101554

We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.

However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.

Diabetes balance

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2 people found this helpful

I found great benefits in balancing my diabetes.

Irritable Bowel Syndrome details

Magnesium boosts colonic activity

Harvey RF, Read AE. Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome. Gut. 1973;14:983.

We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.

Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.

Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.

Effective soothing relief

Most Useful Review

139 people found this helpful

The effect is noticeable from the very first capsule! I have a neurological disability and regularly take magnesium supplements. This magnesium is very good; it quickly relaxes my spasticity and helps me sleep better if taken in the evening. It also soothes my irritable bowel syndrome, with abdominal pains easing quickly. I'm very pleased with my purchase and shared it with my mum. I'll definitely order more.

Weight Loss details

Significant weight loss

3 people found this helpful

Super magnesium! I had tried magnesium from another brand, which was decent, but this one seems much better. Surprisingly, I've noticed my cravings for sweets have disappeared! I've never struggled with my weight, but somehow I gained a few pounds recently. At over fifty, I found it challenging to shed them. After some tests, my doctor prescribed D3, ferritin in the morning, and magnesium in the evening. With a slight adjustment to my diet, I've lost seven kilograms in just four months. I would not have believed that vitamin deficiency could hinder weight loss, but it clearly does! Plus, I've started sleeping much better since taking magnesium. Thanks for reading, ladies!

Cold details

MPM performance in cold environments

Based on 4 Researches

Liu J, Zhang J, Li A, Xia X, Chen J. Effect of fly ash and curing temperature on the properties of magnesium phosphate repair mortar. Sci Rep. 2024;14:15512. doi:10.1038/s41598-024-66581-1

We examined how incorporating fly ash into magnesium phosphate repair mortar (MPM) influences its effectiveness in cold environments. Our investigation revealed that fly ash modifies the microstructure of the MPM, enhancing its performance without affecting the setting time or fluidity significantly.

We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.

Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.

Essential for colds

Most Useful Review

Great for colds, this is a must-have product of mine. The large size means it lasts a long time. Elderberry is packed with benefits...

Depression details

Magnesium intake reduces depression risk

Hajhashemy Z, Shirani F, Askari G. Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis of Epidemiologic Studies. Nutr Rev. 2025;83:217. doi:10.1093/nutrit/nuae056

We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.

Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.

Reduced anxiety

Most Useful Review

16 people found this helpful

Every woman should consider magnesium, as deficiency can lead to heart issues and affect mental health, causing anxiety and depression. After taking one capsule daily, my leg cramps vanished, I became calmer, and my insomnia improved significantly. I find it a bargain for six months' supply.

Premenstrual Syndrome details

1 people found this helpful

I can't praise magnesium enough! Since I started taking it in January, I've slept well, felt less irritable, and had a much easier time during my menstrual cycle. My headaches have significantly reduced, and I have a great mood throughout the day. Additionally, it supports bone density and helps manage inflammation, cardiovascular health, and metabolic factors. The product quality is exceptional with high-quality ingredients.

Sleep Apnea details

Magnesium's role in sleep apnea

Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. doi:10.1016/j.jad.2024.05.002

We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.

7.5

Reduced tension

Most Useful Review

778 people found this helpful

This magnesium offers excellent value for money. I take one capsule at night, and it significantly improves my sleep while reducing nervous tension. The capsules are large but easy to swallow.

Autoimmune Disorder details

Magnesium shows promise for RA treatment

Based on 10 Researches

Laragione T, Harris C, Gulko PS. Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways. Nutrients. 2024;16. doi:10.3390/nu16234247

We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.

Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.

Quick relaxation

Most Useful Review

139 people found this helpful

The effects were noticeable within my first capsule! With a neurological disability, I regularly take magnesium. This particular one works effectively; my spasticity relaxes quickly and aids my sleep, so it’s best taken in the evening. It alleviates my irritable bowel syndrome, and I’m very pleased with my purchase.

Leg Cramps details

Barna O, Lohoida P, Holovchenko Y, Bazylevych A, Velychko V, et al. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps. Nutr J. 2021;20:90. doi:10.1186/s12937-021-00747-9

Likely Ineffective

Based on 17 Researches

Magnesium oxide treats leg cramps

We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.

Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.

The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.

Cramps disappeared

Most Useful Review

714 people found this helpful

Initially, when I began taking magnesium each evening, I did not notice much improvement apart from enhanced sleep quality. However, after a month and a half, I realised I hadn't experienced night leg cramps for a while. Overall, my mood improved, and I felt less irritable, which was a pleasant change.

Migraine details

Magnesium reduces migraine symptoms

Based on 21 Researches

Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.

Improved migraines

Most Useful Review

7 people found this helpful

One of my favourite brands, with one minor downside: it may cause looseness of the stool due to citrate. I take magnesium for muscle cramps and headaches, using 10 mg per kg of body weight. I weigh roughly 50 kg, so the dosage works perfectly. Since using this supplement, I’ve had to take fewer capsules than various other brands. Overall, it's effective, especially for ensuring I maintain adequate magnesium levels for my health.

Chronic Fatigue Syndrome details

Magnesium potentially benefits CFS patients

Based on 5 Researches

Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.

We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.

Reduced muscle tension

Most Useful Review

11 people found this helpful

This supplement effectively alleviates various symptoms of chronic fatigue syndrome, including nervous and muscle tension, cravings, poor sleep, and headaches. I noticed improvements after two years of regular use, transforming me from a tired individual to a more balanced person.

Rash details

Magnesium affects rash treatment efficacy

Based on 2 Researches

Neckermann G, Bavandi A, Meingassner JG. Atopic dermatitis-like symptoms in hypomagnesaemic hairless rats are prevented and inhibited by systemic or topical SDZ ASM 981. Br J Dermatol. 2000;142:669.

We investigated how magnesium deficiency affects rash in hairless rats, which develop a severe, itchy rash resembling atopic dermatitis. In our study, we tested a derivative called SDZ ASM 981, given either systemically or topically. Remarkably, oral treatment with SDZ ASM 981 significantly cleared the rash within just one day.

Furthermore, this treatment reduced several inflammatory markers, showing promising results for both prevention and therapy. This indicates that magnesium's role might be crucial in managing similar skin conditions in humans, reinforcing the value of this rat model for effective treatment evaluation.

7.5

Mood boost but rash

Most Useful Review

56 people found this helpful

These capsules really work! After completing a course, I felt rejuvenated with an incredible burst of energy and an uplifting mood. However, do not exceed the recommended dosage, as this may trigger an allergic reaction. I experienced itching and a rash, which subsided after I stopped taking the capsules.

Constipation details

Effective treatment for chronic constipation

Based on 22 Researches

Morishita D, Tomita T, Mori S, Kimura T, Oshima T, et al. Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial. Am J Gastroenterol. 2021;116:152. doi:10.14309/ajg.0000000000000942

We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.

Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.

Importantly, there were no severe treatment-related side effects reported during the trial.

7.5

Effective for constipation

Most Useful Review

226 people found this helpful

I’ve been taking magnesium for a long time and am always pleased with the results. It calms and acts as a mild laxative, making it great for those suffering from constipation. My family and I all take one capsule a day and it keeps us happy!

Cardiovascular Disease details

Nielsen FH. The Role of Dietary Magnesium in Cardiovascular Disease. Nutrients. 2024;16. doi:10.3390/nu16234223

Magnesium's impact on heart health

We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.

Effective for insomnia

Most Useful Review

6 people found this helpful

Recommended for maintaining good health! I've heard that a lack of magnesium can increase the risk of insomnia and cardiovascular disease. Since I started taking it an hour before bed, I now fall asleep more quickly. It's been three weeks, and it helps my insomnia significantly. The supplement is large, so be cautious if you struggle to swallow. Magnesium is vital for health support, and I intend to continue taking it.

Common Cold details

Restless legs improvement

1 people found this helpful

I purchased this magnesium for my mother, who suffers from restless legs syndrome, particularly at night. After just three doses, she began to sleep peacefully, which is fantastic! It highlights the importance of maintaining proper magnesium levels in the body.

Indigestion details

Helpful for indigestion

Great product! Magnesium oxide is a fantastic ingredient for my indigestion, heartburn, and constipation. It even aids my sleep, alleviates muscle cramps, and works best when taken at night with no aftertaste. The size of the capsule is good and easy to swallow.

Liver Disease details

5 people found this helpful

I regularly purchase magnesium supplements, as many people are deficient, especially those under stress or with demanding lifestyles. After struggling with chronic migraines and using harsh medications that burdened my liver, I took 400 mg of magnesium with Vit D before bed. My migraines vanished, and my blood pressure normalised. A follow-up blood test revealed my magnesium levels were at the lower limit of normal. I highly recommend this product.

Heart Attack details

Magnesium implantation improves heart recovery

Based on 23 Researches

Wang B, Pan S, Nie C, Zou R, Liu J, et al. Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats. Sci Rep. 2024;14:10959. doi:10.1038/s41598-024-60609-2

We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.

Normalised heart rhythm

Most Useful Review

4 people found this helpful

This magnesium is easy to take and the dosage is good. I've observed positive effects, such as reduced seizures in an elderly person and calmer demeanour. It assists in normalising heart rhythm, but I recommend other sedative options for a better effect.

Heart Disease details

Magnesium supplements lower heart failure risk

Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. doi:10.1161/JAHA.124.038870

We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.

In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.

Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.

7.5

Stabilised heart

Most Useful Review

546 people found this helpful

I consider these capsules essential for managing my atrial fibrillation because I need magnesium. Having taken this complex for two years, I've noticed my heart works more steadily and no longer goes out of rhythm with the slightest excitement. The capsules are small and easy to take, although my wife prefers to empty the powder into her food. The packaging confirms this is acceptable. I highly recommend this product!

Heartburn details

Magnesium alginate offers heartburn relief

Based on 6 Researches

Bianchetti M, Peralta S, Nicita R, Aragona SE, Ciprandi G. Emerging from gastroesophageal reflux (EMERGE): An Italian survey - II the viewpoint of the patient. J Biol Regul Homeost Agents. 2018;32:983.

We explored the impact of a new treatment, Marial®, on patients suffering from gastroesophageal reflux disease (GERD). In a large survey involving 56 gastroenterological offices across Italy, patients were treated with either proton pump inhibitors (PPIs), a combination of PPIs and an additional remedy, or the Marial® formulation containing magnesium alginate. The results showed that both Marial® and the combination therapy significantly reduced heartburn symptoms, with Marial® proving to be more effective than the combination. Overall, patients reported a marked improvement in their GERD-related symptoms.

No heartburn experienced

Most Useful Review

I find this magnesium is fantastic as I experience no heartburn and feel relaxed shortly after taking it at night. It also helps with my menopausal palpitations. Thank you for offering such great value for money!

Nausea details

Hua X, Chen Y, Wu Z, Zheng G, Yang D, et al. Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial. Heliyon. 2024;10:e30342. doi:10.1016/j.heliyon.2024.e30342

Based on 4 Researches

Magnesium effectively reduces PONV

We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.

We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.

Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.

This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.

Effective without nausea

Most Useful Review

A brilliant vitamin! They perform their primary function well. This magnesium is excellent and doesn't induce nausea.

Hair Loss details

3D micropattern enhances hair regrowth

Based on 3 Researches

Ma J, Qin C, Wu J, Zhuang H, Du L, et al. 3D multicellular micropatterning biomaterials for hair regeneration and vascularization. Mater Horiz. 2023;10:3773. doi:10.1039/d3mh00528c

We explored a novel approach to tackle hair loss by using a 3D multicellular micropattern that includes magnesium silicate (MS) nanomaterials. This innovative method involved carefully positioning hair follicle-related cells in a structured network along with vascular cells, all created through advanced bioprinting techniques.

The incorporation of magnesium silicate aimed to enhance both hair follicle potential and the formation of new blood vessels—factors crucial for healthy hair growth. Our findings revealed promising results, showing that this 3D micropattern with MS significantly promoted hair regrowth in models of skin tissue regeneration, including both immunodeficient mice and those with androgenetic alopecia.

Essentially, we demonstrated that integrating magnesium with a well-designed cell arrangement could lead to better hair restoration outcomes. This significant insight contributes to the ongoing search for effective treatments for hair loss, bridging biological engineering and dermatology in the process.

Restores hair growth

Most Useful Review

2 people found this helpful

This supplement improved my sleep and aided in restoring my hair after experiencing severe hair loss. After six months, I noticed significant hair regrowth! I take one capsule in the morning and one at night; the large, tasteless capsules don’t upset my stomach. I'm very satisfied with the results.

Chest Pain details

Magnesium improves chest pain outcomes

Based on 19 Researches

Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.

We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.

Miracle supplement

Most Useful Review

4 people found this helpful

Magnesium supplementation is essential! It supports the nervous, cardiovascular, and cartilage systems. For those with joint pain, it's a miracle supplement. My aunt suffers from osteoarthritis, but since she began taking Magnesium daily, her pain has disappeared. I highly recommend it!

Food Poisoning details

Magnesium oxide shows promise against EHEC

Hirakawa H, Suzue K, Uchida M, Takita A, Kamitani W, et al. A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic , Which Attenuates Virulence. Front Microbiol. 2022;13:883689. doi:10.3389/fmicb.2022.883689

We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.

Constipation relief

Most Useful Review

1 people found this helpful

I had a prescription at the hospital for severe constipation. It was difficult to manage, so I bought a magnesium supplement from a pharmacy. However, the quantity required was inconvenient, leading me to switch to this product. The pills are large, but with enough water, swallowing them is easy. I initially upped my intake to two pills, but found that every other day worked best. My bowel movements improved naturally without discomfort. While I tried another brand of magnesium, it didn’t suit me as well as NOW Foods. I've stocked up on it to ensure I don't run out.

Pelvic Pain details