' 
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
**
Polyunsaturated Fat
0.5 g
**
Monounsaturated Fat
0 g
**
Cholesterol
10 mg
3%
Omega-3 Fish Oil
1000 mg
**
EPA (Eicosapentaenoic Acid)
180 mg
**
DHA (Docosahexaenoic Acid)
120 mg
**
The product is found useful for the following medical conditions
Sinusitis
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 1 Reviews
10
10
Sinusitis improvement
Most Useful Review
Excellent! I was prescribed omega-3 with lemon flavour by my doctor to boost my immunity and thin my blood. Previously, I suffered from sinusitis, which has now completely cleared. I feel more energised and wake up easily.
Migraine
SCIENTIFIC SCORE
Most Likely Effective
Based on 15 Researches
7.5
USERS' SCORE
Excellent
Based on 2 Reviews
9.5
9.5
Eicosapentaenoic acid helps migraines
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Most Relevant Research
We conducted a thorough investigation into how eicosapentaenoic acid (EPA) can impact episodic migraines. In a carefully designed study, we gathered 70 participants who experienced these migraines and divided them into two groups. One group received a high dose of EPA, while the other was given a placebo. This approach ensured that we could see the true effects of EPA without bias.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
9.5
Migraine relief
Most Useful Review
Taking these capsules regularly has normalised my sleep and significantly improved my migraines. When I feel symptoms starting, I take my pills, add extra magnesium, and my migraine typically subsides within hours, compared to previously being incapacitated for half a day. My PMS and menstruation have also become much more manageable with regular magnesium intake, and my chronic nasopharynx pain has lessened. I've also been taking omega-3 and other supplements, which may contribute. I've experienced no side effects; the quality is excellent and natural.
Stroke
SCIENTIFIC SCORE
Most Likely Effective
Based on 8 Researches
7.5
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9
Eicosapentaenoic Acid reduces stroke risk
Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies.
Most Relevant Research
We investigated the relationship between eicosapentaenoic acid (EPA) levels and stroke risk by pooling data from 29 international studies, involving over 183,000 participants. Our goal was to understand how circulating and tissue omega-3 fatty acid levels, specifically EPA, affect the occurrence of different types of stroke, including total, ischemic, and hemorrhagic strokes.
Our findings revealed that higher levels of EPA are linked to a lower risk of both total and ischemic strokes. For participants who had the highest levels of EPA, there was a 17% lower incidence of total strokes compared to those with the lowest levels, and an 18% reduction in ischemic strokes. This suggests that increasing EPA intake could be beneficial in reducing the risk of these stroke types.
However, it's important to note that EPA showed no significant relationship with hemorrhagic stroke risk. This indicates that while EPA may help prevent some stroke types, it does not appear to reduce the risk of bleeding strokes. These results were consistent across various demographics, regardless of whether participants had a history of atrial fibrillation or existing cardiovascular disease. Overall, our study presents strong evidence that EPA can be a valuable addition to dietary strategies aimed at reducing stroke risks.
Our findings revealed that higher levels of EPA are linked to a lower risk of both total and ischemic strokes. For participants who had the highest levels of EPA, there was a 17% lower incidence of total strokes compared to those with the lowest levels, and an 18% reduction in ischemic strokes. This suggests that increasing EPA intake could be beneficial in reducing the risk of these stroke types.
However, it's important to note that EPA showed no significant relationship with hemorrhagic stroke risk. This indicates that while EPA may help prevent some stroke types, it does not appear to reduce the risk of bleeding strokes. These results were consistent across various demographics, regardless of whether participants had a history of atrial fibrillation or existing cardiovascular disease. Overall, our study presents strong evidence that EPA can be a valuable addition to dietary strategies aimed at reducing stroke risks.
9.5
Reduces stroke risk
Most Useful Review
The work concluded that a high level of Omega-3 polyunsaturated fatty acids in blood reduces the risk of minor stroke by 40%. Omega-3 acids clear the walls of blood vessels from excess "bad" cholesterol, preventing “cholesterol plaques” and improving blood viscosity.
Ulcer
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
8.4
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9
Eicosapentaenoic acid aids ulcer healing
Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-κB and TGF-β/ EGFR signaling pathways.
Most Relevant Research
We examined how Eicosapentaenoic acid (EPA) could protect against ulcerative colitis (UC), a chronic condition that inflames the large intestine. In our research, we used acetic acid to induce UC in rats, administering oral EPA for 28 days in doses of 300 and 1000 mg/kg before the acetic acid treatment.
Our findings were quite promising. EPA appeared to significantly alleviate UC symptoms, as seen in the improved colonic health of the rats. We noted that EPA treatment not only reduced inflammation but also helped restore the balance between oxidants and antioxidants in the body. This balance is crucial for maintaining a healthy gut environment and reducing tissue damage.
Moreover, EPA led to the enhancement of protective proteins in the colon, while it suppressed markers associated with inflammation. This included reductions in substances that typically signal more inflammation, which suggests that EPA has a dual role—enhancing protective factors while diminishing harmful responses. We believe these insights highlight the potential of EPA as a therapeutic agent for managing UC more effectively.
Our findings were quite promising. EPA appeared to significantly alleviate UC symptoms, as seen in the improved colonic health of the rats. We noted that EPA treatment not only reduced inflammation but also helped restore the balance between oxidants and antioxidants in the body. This balance is crucial for maintaining a healthy gut environment and reducing tissue damage.
Moreover, EPA led to the enhancement of protective proteins in the colon, while it suppressed markers associated with inflammation. This included reductions in substances that typically signal more inflammation, which suggests that EPA has a dual role—enhancing protective factors while diminishing harmful responses. We believe these insights highlight the potential of EPA as a therapeutic agent for managing UC more effectively.
9.5
Healed gastric ulcers
Most Useful Review
Omega 3 is an excellent remedy for treating ulcers. After starting the supplement, I found that my ulcer pain diminished in just a few days, and healing began swiftly. Omega 3 not only aids digestion but also normalises fat metabolism. Additionally, it is beneficial for joint health and helps reduce inflammation. It plays a crucial role in brain function, making it easier to think and store memories. I highly recommend taking 3-4 capsules daily with meals for optimal effects.
Heartburn
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 27 Reviews
9.4
9.5
No side effects
Most Useful Review
Great quality fish oil at a reasonable price! It works well for me with no side effects like heartburn or belching. I've noticed positive effects on my cognitive abilities, and my skin improved. It’s particularly beneficial in the triglyceride form.
Frozen Shoulder
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 2 Reviews
9.3
9.5
Improved mobility
Most Useful Review
Changed my life. This product is among the best I’ve taken. It aided my digestion and joint issues. I had torn labrums in both shoulders, and it helped me recover to around 90%. I also suffered from severe acid reflux, but I can now enjoy coffee without any problems. Great stuff!
Reflux
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 10 Reviews
9.3
9.5
Reflux improvement
Most Useful Review
Changed my life. This product has been one of the best I've taken, aiding my digestion and joint issues. I had torn both my shoulder labrums, and this supplement has helped me recover to about 90%. Previously, I struggled with severe acid reflux, but now I can enjoy coffee without any problems. Excellent product!
Asthma
SCIENTIFIC SCORE
Most Likely Effective
Based on 15 Researches
7.4
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
9
Eicosapentaenoic acid improves asthma
Effects of low-dust forages on dust exposure, airway cytology, and plasma omega-3 concentrations in Thoroughbred racehorses: A randomized clinical trial.
Most Relevant Research
We compared how different types of forage affected asthma in Thoroughbred racehorses. Our focus was on assessing dust exposure, airway health, and the presence of eicosapentaenoic acid (EPA), an omega-3 fatty acid known for its anti-inflammatory properties. The horses were randomly assigned to three diets: dry hay, steamed hay, or haylage for a period of six weeks.
Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.
In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.
Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.
In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.
9.5
Asthma risk reduction
Most Useful Review
This supplement is remarkable. It can help reduce the risk of asthma in children when mothers take fish oil. It also offers numerous other benefits, including improved metabolic rate and support for various health issues, such as rheumatoid arthritis and depression.
Hypertension
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.6
USERS' SCORE
Excellent
Based on 4 Reviews
9.2
9
Eicosapentaenoic acid benefits hypertension
5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway.
Most Relevant Research
We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.
9.5
Effective against hypertension
Most Useful Review
Omega-3 Fish Oil works brilliantly! I prescribe it to my patients with cardiovascular issues, including hypertension and arrhythmias. It's important to remember that individuals may have a specific intolerance to the components of the medication.
Psoriasis
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
6.9
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
8
EPA benefits psoriatic skin health
Eicosapentaenoic Acid Influences the Lipid Profile of an In Vitro Psoriatic Skin Model Produced with T Cells.
Most Relevant Research
We aimed to understand how eicosapentaenoic acid (EPA) affects psoriasis, a skin condition known for causing redness, irritation, and thickened skin. By creating skin models that reflect both healthy and psoriatic conditions, we were able to assess the impact of EPA directly on lipid profiles—a key factor in skin health.
Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.
More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.
Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.
More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.
9.5
Nutritional support
Most Useful Review
Omega-3 polyunsaturated fatty acids (PUFAs) are increasingly recognised for psoriasis. They not only aid in medication but also provide essential nutritional support. DHA and EPA in Omega-3 help stabilise immune functions, leading to reduced inflammation and fewer relapses in psoriasis.
Yeast Infection
SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
8.5
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
9
Eicosapentaenoic acid combats yeast biofilms
Eicosapentaenoic acid as an antibiofilm agent disrupts mature biofilms of .
Most Relevant Research
We set out to explore how eicosapentaenoic acid (EPA), a type of healthy fat, can disrupt the mature biofilms formed by a significant human fungal pathogen. These biofilms are important since they enhance the pathogen's ability to cause infections. Our investigation focused on the effects of a 1 mM EPA treatment on these established biofilms.
Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.
We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.
Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.
Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.
We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.
Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.
9.5
Promotes hair growth
Most Useful Review
Hair grows quite remarkably, almost like a yeast infection. I suggest giving it a try.
Arthritis
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.3
USERS' SCORE
Excellent
Based on 5 Reviews
9.1
8
Eicosapentaenoic acid aids arthritis
Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, on patients with rheumatoid arthritis (RA). This analysis gathered data from eighteen randomized controlled trials involving over a thousand RA patients, ensuring a comprehensive look at its impact.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
9.5
Joint health
Most Useful Review
Fish oil is beneficial for the brain and boosts the immune system. It lowers blood pressure and improves joint mobility, which is vital for those suffering from arthritis. My therapist recommended it to stabilise my cholesterol. This is a high-quality product at a reasonable price. Our family takes it daily, and we notice no side effects. Highly recommended for everyone!
Headache
SCIENTIFIC SCORE
Most Likely Effective
Based on 11 Researches
7
USERS' SCORE
Excellent
Based on 7 Reviews
9.1
9.5
Eicosapentaenoic acid reduces migraines
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Most Relevant Research
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
9.5
Headache relief
Most Useful Review
I've been taking Omega for four months, and it has greatly improved my blood vessel health and eliminated my headaches. This Omega has a pleasant lemon flavour, and I find the quantity sufficient for my needs. I was sceptical about dietary supplements, but I no longer need medication for pressure issues, and I'm genuinely pleased with the results.
Leg Cramps
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 5 Reviews
9.1
9.5
Heart health improved
Most Useful Review
I occasionally experienced leg cramps in my twenties. After taking Omega 3 for years, I appreciate the lemon flavour, and it has effectively alleviated these cramps. It’s true that Omega 3 benefits the heart; stopping for just three days makes me aware of it. It works well for me.
Common Cold
SCIENTIFIC SCORE
Most Likely Effective
Based on 1 Researches
8
USERS' SCORE
Excellent
Based on 4 Reviews
9
8
DHA reduces infant cold symptoms
Prenatal docosahexaenoic acid supplementation and infant morbidity: randomized controlled trial.
Most Relevant Research
We conducted a double-blind randomized controlled trial to understand how prenatal supplementation of docosahexaenoic acid (DHA) might influence infant health, particularly concerning the common cold. Pregnant women were given either a daily dose of 400 mg of DHA or a placebo starting at 18 to 22 weeks of gestation until childbirth.
Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.
While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.
Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.
This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.
Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.
While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.
Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.
This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.
9.5
Effective for colds
Most Useful Review
Works! My skin was extremely dry, and I suffered from frequent cold sores. However, alongside vitamin D, these capsules have alleviated my issues. My hair also appears healthier now! They work effectively, and I recommend them for health improvements!
Menopause
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
6.1
USERS' SCORE
Very Good
Based on 4 Reviews
8.9
9
Eicosapentaenoic acid and estradiol
Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women.
Most Relevant Research
We explored the relationship between eicosapentaenoic acid (EPA) intake and estradiol levels in women, specifically focusing on its effects during menopause. The study utilized data from the National Health and Nutrition Examination Survey, which included dietary interviews and serum estradiol level measurements.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
8.8
Menopause relief
Most Useful Review
The condition of my skin and hair has improved. Omega-3 PUFAs, which the body cannot synthesise, are essential for various functions. They are particularly important for women during menopause, helping alleviate its symptoms, and reducing menstrual pain. I've noticed a positive effect on my digestive tract as well. After two to three weeks of taking two capsules daily, I experienced noticeable improvements. I will continue this as a preventive measure for my health and well-being.
Nausea
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 10 Reviews
8.9
9.5
No nausea noted
Most Useful Review
Good budget omega. Natrol has produced quality supplements for 35 years. Their omega-3s are from fish muscles, molecularly distilled to remove impurities. The capsules have a light lemon aroma. Although not the smallest, they are easy to swallow. I take them morning and evening. I experienced no side effects, including nausea. Omega-3 helped normalise my cholesterol a few years ago. I take it in courses and have noticed benefits for my skin as well, particularly on my elbows and hands.
Osteoporosis
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.3
USERS' SCORE
Very Good
Based on 8 Reviews
8.9
9
Eicosapentaenoic acid protects bone health
Eicosapentaenoic acid supplementation modulates the osteoblast/osteoclast balance in inflammatory environments and protects against estrogen deficiency-induced bone loss in mice.
Most Relevant Research
We evaluated the effects of eicosapentaenoic acid (EPA) on osteoporosis, particularly in how it impacts the balance between osteoblasts (the cells that build bone) and osteoclasts (the cells that break down bone). In an experimental setup, we used mouse bone marrow stem cells and macrophages to study how EPA could counteract the negative effects of inflammation, which can lead to osteoporosis.
By simulating an inflammatory environment with TNF-α, we discovered that EPA helped restore the ability of stem cells to differentiate into osteoblasts, which is crucial for bone formation. Furthermore, we explored how EPA influenced the communication between osteoblasts and osteoclasts, finding that it regulated important factors involved in bone resorption.
When we tested the effects of EPA in a mouse model of estrogen deficiency—an established cause of bone loss in postmenopausal women—we observed significant protective effects against osteoporosis. This suggests that EPA could play a valuable role in maintaining bone health and preventing bone loss related to hormonal changes, providing a promising avenue for future osteoporosis treatments.
By simulating an inflammatory environment with TNF-α, we discovered that EPA helped restore the ability of stem cells to differentiate into osteoblasts, which is crucial for bone formation. Furthermore, we explored how EPA influenced the communication between osteoblasts and osteoclasts, finding that it regulated important factors involved in bone resorption.
When we tested the effects of EPA in a mouse model of estrogen deficiency—an established cause of bone loss in postmenopausal women—we observed significant protective effects against osteoporosis. This suggests that EPA could play a valuable role in maintaining bone health and preventing bone loss related to hormonal changes, providing a promising avenue for future osteoporosis treatments.
8.8
Supports joint health
Most Useful Review
Omega-3s support joint health and help prevent osteoporosis. They reduce inflammation and fight bone loss, alleviating joint pain, and mitigate symptoms of rheumatoid arthritis while slowing cartilage degradation in arthrosis. The fish oil is of high quality with no side effects like heartburn. I take it regularly and find it excellent value for money.
Bruise
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
No bruising effects
Most Useful Review
Very good omega; it did not cause any bruising.
Cancer
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.5
USERS' SCORE
Very Good
Based on 3 Reviews
8.8
9
Impact of Omega-3 on Cancer
Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression.
Most Relevant Research
We explored the effects of eicosapentaenoic acid, a type of omega-3 fatty acid, on pancreatic cancer using a specially designed mouse model that closely mimics human disease. This model allowed us to examine how adding omega-3 to the diet could impact cancer progression.
Our findings revealed that a diet enriched with eicosapentaenoic acid led to a significant reduction in tumor size and metastasis to the lungs and liver. We also observed a trend toward improved survival rates in the mice that received this dietary intervention compared to those that did not.
Interestingly, the treatment not only changed the fatty acid profile in the tumors but also influenced certain cellular processes. We noted an increase in apoptosis, or programmed cell death, without affecting how fast the cancer cells were growing. Additionally, there was a marked decrease in tumor fibrosis associated with lower levels of Sonic Hedgehog, a key player in pancreatic cancer development.
Overall, our research suggests that eicosapentaenoic acid holds promise as a dietary intervention for cancer treatment, potentially opening new doors for incorporating nutritional strategies in managing pancreatic cancer.
Our findings revealed that a diet enriched with eicosapentaenoic acid led to a significant reduction in tumor size and metastasis to the lungs and liver. We also observed a trend toward improved survival rates in the mice that received this dietary intervention compared to those that did not.
Interestingly, the treatment not only changed the fatty acid profile in the tumors but also influenced certain cellular processes. We noted an increase in apoptosis, or programmed cell death, without affecting how fast the cancer cells were growing. Additionally, there was a marked decrease in tumor fibrosis associated with lower levels of Sonic Hedgehog, a key player in pancreatic cancer development.
Overall, our research suggests that eicosapentaenoic acid holds promise as a dietary intervention for cancer treatment, potentially opening new doors for incorporating nutritional strategies in managing pancreatic cancer.
8.8
Cancer prevention benefits
Most Useful Review
"Mega" omega is wonderful fish oil of excellent quality! It contains a natural fish oil concentrate rich in polyunsaturated fatty acids, which dramatically lower cholesterol levels, supporting cardiovascular health. Omega 3 is noted for slowing tumour development and is effective in preventing cancer. It aids in skin disease treatment and improves healing. This supplement also normalises digestion and fat metabolism, alleviates arthritis pain, and is essential for brain activity. Recommended dosage is 3-4 capsules daily with meals.
Chest Pain
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
6.5
USERS' SCORE
Very Good
Based on 6 Reviews
8.8
7
Eicosapentaenoic acid showed mixed results
Improvement of coronary vasomotion with eicosapentaenoic acid does not inhibit acetylcholine-induced coronary vasospasm in patients with variant angina.
Most Relevant Research
We examined how eicosapentaenoic acid (EPA), a key ingredient found in fish oil, impacts chest pain in patients with variant angina. Our study followed 22 individuals with this condition, where we infused acetylcholine, a substance known to cause coronary vasospasm, both before and after a four-month course of EPA treatment (1.8 g/day for 12 patients).
In the group that did not receive EPA, we observed no changes in how their coronary arteries responded to acetylcholine over time. However, for those treated with EPA, the results were quite intriguing. In non-spastic areas, the response shifted from vasoconstriction (narrowing) to vasodilation (widening). This indicates a notable improvement in how these arteries are functioning.
Yet, when it came to spastic sites where vasospasm had occurred, the coronary arteries remained responsive to acetylcholine, and the vasospasm persisted despite the EPA treatment. Thus, while EPA enhanced coronary responsiveness in some areas, it did not eliminate the acetylcholine-induced coronary vasospasms associated with variant angina.
In the group that did not receive EPA, we observed no changes in how their coronary arteries responded to acetylcholine over time. However, for those treated with EPA, the results were quite intriguing. In non-spastic areas, the response shifted from vasoconstriction (narrowing) to vasodilation (widening). This indicates a notable improvement in how these arteries are functioning.
Yet, when it came to spastic sites where vasospasm had occurred, the coronary arteries remained responsive to acetylcholine, and the vasospasm persisted despite the EPA treatment. Thus, while EPA enhanced coronary responsiveness in some areas, it did not eliminate the acetylcholine-induced coronary vasospasms associated with variant angina.
9.5
No chest pain
Most Useful Review
I take 2 capsules each morning with breakfast. After 3 weeks, I've noticed improved endurance during cardio workouts, and for the first time, I have no knee pain, which used to trouble me during lunges and squats. I experienced some mouth and stomach discomfort previously, but now, everything is excellent!
Chronic Fatigue Syndrome
SCIENTIFIC SCORE
Most Likely Effective
Based on 5 Researches
7.9
USERS' SCORE
Very Good
Based on 13 Reviews
8.8
9.5
Eicosapentaenoic acid benefits CFS
Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes.
Most Relevant Research
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
9.5
Eliminated fatigue
Most Useful Review
Works! My skin was excessively dry, and I was often fatigued and suffering from cold sores. Since taking these capsules alongside vitamin D, my issues have been resolved, and my hair appears healthier. It truly works, and I wholeheartedly recommend it for addressing chronic fatigue syndrome!
Depression
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.1
USERS' SCORE
Very Good
Based on 7 Reviews
8.8
8
Eicosapentaenoic acid may reduce depression
The Efficacy of Omega-3 Fatty Acids as the Monotherapy for Depression: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.
Most Relevant Research
We conducted a study to explore the effectiveness of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, in treating major depressive disorder (MDD). Over the course of 12 weeks, 60 participants suffering from MDD were divided into two groups: one received 3.2 grams of EPA daily, while the other group was given a placebo, which was soybean oil.
Throughout the study, we assessed the severity of depression using the Hamilton Rating Scale for Depression (HRSD). What we found was promising. The group taking EPA experienced significantly lower HRSD scores at various checkpoints—specifically at weeks 4, 6, 8, and 12—indicating a reduction in depressive symptoms. Although the rates of remission and response were higher in the EPA group compared to the placebo group, these findings did not achieve statistical significance.
Overall, while EPA shows potential as a treatment for depression, further research is needed to solidify its role. Our findings suggest that it may be an alternative option for MDD patients seeking additional treatment pathways.
Throughout the study, we assessed the severity of depression using the Hamilton Rating Scale for Depression (HRSD). What we found was promising. The group taking EPA experienced significantly lower HRSD scores at various checkpoints—specifically at weeks 4, 6, 8, and 12—indicating a reduction in depressive symptoms. Although the rates of remission and response were higher in the EPA group compared to the placebo group, these findings did not achieve statistical significance.
Overall, while EPA shows potential as a treatment for depression, further research is needed to solidify its role. Our findings suggest that it may be an alternative option for MDD patients seeking additional treatment pathways.
9.5
Depression relief
Most Useful Review
This brand of fish oil has helped lift my permanent depression. There's no unpleasant fish taste or odour, and it works well compared to other Omega-3 brands I've tried.
Epilepsy
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.1
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
2
No benefit observed in epilepsy
Effects of essential fatty acid supplementation in dogs with idiopathic epilepsy: a clinical trial.
Most Relevant Research
We conducted a study to investigate whether essential fatty acid supplementation, specifically eicosapentaenoic acid (EPA), could help control idiopathic epilepsy in dogs. This involved a carefully designed approach where fifteen dogs received a daily dose of purified Omega-3 oil for 12 weeks, followed by a 12-week placebo period using olive oil.
Throughout the study, dog owners diligently recorded seizure frequency and severity, along with any side effects that may have arisen. Despite hopes that these essential fatty acids would provide some benefit, the results were quite clear: we found no significant reduction in seizure frequency or severity for those dogs receiving the Omega-3 supplement compared to the placebo group.
These findings suggest that while EPA is a popular supplement often touted for various health benefits, it does not appear to have a positive effect on managing idiopathic epilepsy in dogs. This research can help pet owners make informed decisions about treatment options for their furry companions struggling with seizures.
Throughout the study, dog owners diligently recorded seizure frequency and severity, along with any side effects that may have arisen. Despite hopes that these essential fatty acids would provide some benefit, the results were quite clear: we found no significant reduction in seizure frequency or severity for those dogs receiving the Omega-3 supplement compared to the placebo group.
These findings suggest that while EPA is a popular supplement often touted for various health benefits, it does not appear to have a positive effect on managing idiopathic epilepsy in dogs. This research can help pet owners make informed decisions about treatment options for their furry companions struggling with seizures.
8.8
Good source oils
Most Useful Review
Natrol Omega-3 Purified Fish Oil in lemon flavour is a great buy. I use it as an excellent source of oils for managing my epilepsy.
Pneumonia
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Family-friendly product
Most Useful Review
An excellent product for the entire family to consume. The dosage is optimal. My mother was prescribed it following her pneumonia.
Rosacea
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Improved rosacea
Most Useful Review
I find this omega 3 supplement essential for my health and beauty, recommended by my nutritionist. It effectively smooths my skin, making it glow and nourish without peeling, while also reducing my rosacea. Omega 3 is crucial for the absorption of vitamin D3, and I believe fatty acids are vital for women's health; I take them almost continuously!
Tonsillitis
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Improved recovery
Most Useful Review
I was desperate from walking with my child to hospitals due to chronic tonsillitis and rhinitis. After searching for a solution, I found that taking Ant Bark and Black Walnut during illness helped my child endure colds better, and we avoided antibiotics. We also restored gut health with probiotics and other supplements. The recovery took time, but now we only take a vitamin complex, and my child is as healthy as other kids. Thanks to iHerb and all the reviewers!
Anxiety
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
6.9
USERS' SCORE
Very Good
Based on 7 Reviews
8.7
8
EPA alleviates anxiety in mice
Omega-3 alleviates behavioral and molecular changes in a mouse model of stress-induced juvenile depression.
Most Relevant Research
We examined how eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, influences anxiety levels in a juvenile mouse model affected by stress. Using an ultrasound (US) stress method, we subjected one-month-old C57/BL6 mice to varying sound frequencies that can mimic depressive-like symptoms.
Alongside the stress exposure, these mice received either an omega-3 food supplement containing EPA and docosahexaenoic acid (DHA) or a placebo. The results were striking: mice treated with the omega-3 supplement showed no signs of anxiety or depression, while those given the placebo exhibited increased anxiety, lowered motivation for reward, and elevated stress hormones in their blood.
Additionally, our metabolomic analysis revealed beneficial changes, particularly in brain energy metabolism, thanks to the omega-3 treatment. These findings suggest that eicosapentaenoic acid may help alleviate anxiety in stressful situations, implying its potential role as a therapeutic option for tackling anxiety and depression, especially in young populations.
Alongside the stress exposure, these mice received either an omega-3 food supplement containing EPA and docosahexaenoic acid (DHA) or a placebo. The results were striking: mice treated with the omega-3 supplement showed no signs of anxiety or depression, while those given the placebo exhibited increased anxiety, lowered motivation for reward, and elevated stress hormones in their blood.
Additionally, our metabolomic analysis revealed beneficial changes, particularly in brain energy metabolism, thanks to the omega-3 treatment. These findings suggest that eicosapentaenoic acid may help alleviate anxiety in stressful situations, implying its potential role as a therapeutic option for tackling anxiety and depression, especially in young populations.
8.8
Reduces anxiety effectively
Most Useful Review
Excellent Omega. This is one of my favourites. Omega-3 supplementation has helped me with my anxiety and overall well-being. I find it easier to obtain essential fatty acids through supplements rather than consuming fatty fish regularly. I take 1-2 capsules daily with breakfast, and I believe Omega-3 is essential for my health. It supports blood vessel health and overall cardiovascular system functionality, making it good value for money.
Cardiovascular Disease
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.3
USERS' SCORE
Very Good
Based on 46 Reviews
8.7
9
EPA's role in diabetic heart health
Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy.
Most Relevant Research
We explored the impact of eicosapentaenoic acid (EPA), a nutrient known for its heart benefits, on diabetic cardiomyopathy (DC), a condition leading to heart failure. Our study focused on diabetic mice and revealed that EPA plays a protective role against DC, particularly by reducing harmful M1-polarized macrophages in the heart.
In our experiments, we found that EPA not only reduces cardiomyocyte injury caused by M1-polarized macrophages but also encourages a shift in macrophages' behavior from M1 to a protective Mox state—not M2. This shift is crucial because Mox macrophages help mitigate the damage inflicted by their M1 counterparts.
We identified heme oxygenase 1 (HO-1) as a key player in maintaining the Mox phenotype. EPA promotes HO-1, which helps curb macrophage M1 polarization and the resulting cardiomyocyte injury. Interestingly, our findings also showed that EPA fosters this protective Mox polarization in monocyte-derived macrophages from diabetic patients, suggesting a broader application for this treatment strategy.
Overall, our study highlights the potential of EPA as a novel approach to combat diabetic cardiomyopathy, emphasizing the importance of macrophage Mox polarization in maintaining heart health in diabetes.
In our experiments, we found that EPA not only reduces cardiomyocyte injury caused by M1-polarized macrophages but also encourages a shift in macrophages' behavior from M1 to a protective Mox state—not M2. This shift is crucial because Mox macrophages help mitigate the damage inflicted by their M1 counterparts.
We identified heme oxygenase 1 (HO-1) as a key player in maintaining the Mox phenotype. EPA promotes HO-1, which helps curb macrophage M1 polarization and the resulting cardiomyocyte injury. Interestingly, our findings also showed that EPA fosters this protective Mox polarization in monocyte-derived macrophages from diabetic patients, suggesting a broader application for this treatment strategy.
Overall, our study highlights the potential of EPA as a novel approach to combat diabetic cardiomyopathy, emphasizing the importance of macrophage Mox polarization in maintaining heart health in diabetes.
9.5
Cardiovascular remedy
Most Useful Review
This "Mega" omega fish oil is superb! It helps reduce cholesterol concentrations, acts as a preventive measure against cardiovascular disease, and has shown potential in cancer prevention. Omega 3 aids in skin conditions, allergies, and arthritis, often providing relief in just days. It's crucial for brain function and normal embryo development. I take 3-4 capsules daily with meals.
Eczema
SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8
USERS' SCORE
Very Good
Based on 4 Reviews
8.6
9
Eicosapentaenoic Acid reduces eczema
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
Most Relevant Research
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
8.8
Improved eczema condition
Most Useful Review
I recommend this product! The capsules are large, as most omega-3s are. My husband took them alongside vitamin D, which significantly improved his dry eczema.
High Cholesterol
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.6
USERS' SCORE
Very Good
Based on 40 Reviews
8.6
9
Eicosapentaenoic acid benefits cholesterol
Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
8.8
Good prevention
Most Useful Review
This Omega-3 fish oil is excellent for health. It provides adequate doses of essential fatty acids and adheres to GMP standards. While it lacks the highest concentration of Omega-3s, it's cost-effective. I use it for skin and hair beauty, and my parents take it to maintain heart health. I recommend it, just follow the instructions of taking two capsules daily with meals.
Sleep Apnea
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 6 Reviews
8.6
9.5
Supports sleep issues
Most Useful Review
Omega-3 fatty acids are essential for everyone. A deficiency can lead to skin issues, concentration loss, sleep disturbances, irritability, chronic fatigue, and worsened allergy reactions. This product has improved my heart function, as well as my skin and hair. They are easy to swallow. I take two capsules daily with food.
Bone Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 14 Reviews
8.5
9.5
No knee pain
Most Useful Review
I take 2 capsules each morning with breakfast, and I've noticed greater endurance during cardio workouts. My knees, which formerly experienced bone pain during lunges and squats, feel perfectly fine now. There are no lingering issues whatsoever. I haven’t encountered any mouth or stomach discomfort, so I rate this as EXCELLENT!
Insomnia
SCIENTIFIC SCORE
Likely Ineffective
Based on 1 Researches
4
USERS' SCORE
Very Good
Based on 3 Reviews
8.4
4
Eicosapentaenoic acid shows limited benefits
Omega-3 fatty acids for a better mental state in working populations - Happy Nurse Project: A 52-week randomized controlled trial.
Most Relevant Research
We explored the effectiveness of eicosapentaenoic acid, a type of omega-3 fatty acid, on insomnia among junior hospital nurses in a well-structured trial. In this study, 80 nurses were randomly assigned to receive either 1200 mg of eicosapentaenoic acid along with 600 mg of docosahexaenoic acid daily or a placebo for 13 weeks.
Our main focus was to see how these supplements influenced insomnia and overall mental health. While we noted some improvements in various measures, including insomnia severity at the 13-week mark, the results didn't demonstrate a significant advantage when compared to the placebo group.
After analyzing data at multiple checkpoints—13, 26, and 52 weeks—we found that the effects of eicosapentaenoic acid on insomnia were not strong enough to conclude it as a beneficial treatment. Overall, while there were some positive indicators at certain times, the overall impact on insomnia was not substantial, leaving us to conclude that more research is needed to confirm any real benefits from omega-3 fatty acids for sleep disturbances.
Our main focus was to see how these supplements influenced insomnia and overall mental health. While we noted some improvements in various measures, including insomnia severity at the 13-week mark, the results didn't demonstrate a significant advantage when compared to the placebo group.
After analyzing data at multiple checkpoints—13, 26, and 52 weeks—we found that the effects of eicosapentaenoic acid on insomnia were not strong enough to conclude it as a beneficial treatment. Overall, while there were some positive indicators at certain times, the overall impact on insomnia was not substantial, leaving us to conclude that more research is needed to confirm any real benefits from omega-3 fatty acids for sleep disturbances.
9.5
Effective for insomnia
Most Useful Review
My husband suffers from insomnia, and the doctor recommended 1000 mg. It has helped him significantly, for which we are grateful.
Autoimmune Disorder
SCIENTIFIC SCORE
Most Likely Effective
Based on 15 Researches
7.4
USERS' SCORE
Very Good
Based on 15 Reviews
8.3
8
Eicosapentaenoic acid benefits MS
The therapeutic effect of PEGlated nanoliposome of pistachio unsaturated oils and its efficacy to attenuate inflammation in multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial phase I.
Most Relevant Research
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore the effects of PEGlated nanoliposome of pistachio unsaturated oils on inflammation in multiple sclerosis (MS). During the study, we treated MS patients with these nanoliposomes enriched with eicosapentaenoic acid, a type of omega-3 fatty acid known for its potential health benefits.
After the treatment, we observed significant improvements in various markers of inflammation. Notably, the levels of docosahexaenoic and eicosapentaenoic acids increased, while the level of matrix metallopeptidase-9, an enzyme linked to inflammation, decreased. This shift indicates a favorable response in how the patients’ bodies were managing inflammation.
Moreover, we noted a Th2-biased response in cytokine levels, which typically suggests a less inflammatory environment. The results showed a significant reduction in the frequency of relapses, lower disability scores, and fewer T2 lesions in patients treated with the nanoliposomes. Overall, our findings suggest that eicosapentaenoic acid treatment may offer promising benefits for managing inflammation associated with multiple sclerosis.
After the treatment, we observed significant improvements in various markers of inflammation. Notably, the levels of docosahexaenoic and eicosapentaenoic acids increased, while the level of matrix metallopeptidase-9, an enzyme linked to inflammation, decreased. This shift indicates a favorable response in how the patients’ bodies were managing inflammation.
Moreover, we noted a Th2-biased response in cytokine levels, which typically suggests a less inflammatory environment. The results showed a significant reduction in the frequency of relapses, lower disability scores, and fewer T2 lesions in patients treated with the nanoliposomes. Overall, our findings suggest that eicosapentaenoic acid treatment may offer promising benefits for managing inflammation associated with multiple sclerosis.
9.5
Supports overall health
Most Useful Review
I've consumed dietary supplements for 18 years and find Omega-3 beneficial for various health aspects, including memory and metabolism. Recommended by my therapist to lower cholesterol, I appreciate the quality here and take them with meals daily. This Omega-3 aids in maintaining good mood and skin, which is essential for treating my autoimmune disorder. It’s a family staple due to its effects and reasonable price.
Heart Disease
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
6.8
USERS' SCORE
Very Good
Based on 57 Reviews
8.3
9
Omega-3 lowers coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
9.5
Cardiovascular benefits
Most Useful Review
"Mega" omega!!! This quality fish oil contains essential omega-3 fatty acids, which significantly lower cholesterol levels and aid in preventing heart disease. Omega-3 has been noted by oncologists for slowing tumour growth and is effective for various skin ailments. It also reduces allergy symptoms in children, aids in wound healing, and helps with arthritis by promoting anti-inflammatory prostaglandins. Omega-3 is vital for brain function and can help pregnant women develop the embryo. I take it daily to regulate fat metabolism and support overall health.
Alzheimer
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
6.9
USERS' SCORE
Very Good
Based on 3 Reviews
8.2
8
Eicosapentaenoic Acid aids Alzheimer's treatment
N-3 polyunsaturated fatty acids attenuate amyloid-beta-induced toxicity in AD transgenic Caenorhabditis elegans via promotion of proteasomal activity and activation of PPAR-gamma.
Most Relevant Research
We investigated how eicosapentaenoic acid (EPA), an n-3 polyunsaturated fatty acid, affects the toxicity linked to Alzheimer’s disease. Using a model of transgenic Caenorhabditis elegans, we observed that treating these worms with EPA led to a decrease in the harmful effects caused by beta-amyloid (Aβ) accumulation, a key contributor to cognitive decline in Alzheimer’s.
Notably, we found that EPA not only reduced the signs of paralysis associated with Aβ but also lowered the production of reactive oxygen species, which are harmful compounds that can damage cells. Additionally, our findings suggested that EPA restored proteasomal activity, helping clear the Aβ build-up.
We further explored the role of PPAR-gamma, a receptor that appears to be crucial for EPA's protective effects. When we used an inhibitor to block PPAR-gamma, the positive outcomes of EPA treatment were no longer evident. This suggests that EPA’s beneficial effects in fighting Aβ-induced toxicity are linked to its ability to activate PPAR-gamma.
Overall, our research underscores the potential of eicosapentaenoic acid as a promising therapeutic option for mitigating Alzheimer's symptoms by enhancing cellular functions.
Notably, we found that EPA not only reduced the signs of paralysis associated with Aβ but also lowered the production of reactive oxygen species, which are harmful compounds that can damage cells. Additionally, our findings suggested that EPA restored proteasomal activity, helping clear the Aβ build-up.
We further explored the role of PPAR-gamma, a receptor that appears to be crucial for EPA's protective effects. When we used an inhibitor to block PPAR-gamma, the positive outcomes of EPA treatment were no longer evident. This suggests that EPA’s beneficial effects in fighting Aβ-induced toxicity are linked to its ability to activate PPAR-gamma.
Overall, our research underscores the potential of eicosapentaenoic acid as a promising therapeutic option for mitigating Alzheimer's symptoms by enhancing cellular functions.
9.5
Memory support
Most Useful Review
Omega-3 is crucial for preventing Alzheimer's and supporting heart health. I take 2 capsules daily and have also tried a higher dosage. This product is effective, with no fishy aftertaste and a pleasant lemon flavour.
Anemia
SCIENTIFIC SCORE
Most Likely Effective
Based on 13 Researches
7.4
USERS' SCORE
Very Good
Based on 2 Reviews
8.2
8
SC411 boosts survival in SCD
SC411 treatment can enhance survival in a mouse model of sickle cell disease.
Most Relevant Research
We explored how a treatment called SC411, which is enriched with eicosapentaenoic acid (EPA), impacts anemia in a specific mouse model of sickle cell disease (SCD). SCD often leads to severe anemia and other serious health issues. Our investigation revealed that SC411 increased the levels of both docosahexaenoic acid (DHA) and EPA in the blood, which are essential fatty acids known to have beneficial effects on health.
Furthermore, we observed that SC411 helped decrease harmful arachidonic acid levels and reduced the sickling of red blood cells, thereby potentially alleviating some of the pain and complications associated with the disease. The treatment not only improved cerebral blood flow but also seemed to enhance cognitive functions, like memory, in the mice.
Overall, the results highlighted that treatment with SC411 could significantly enhance survival rates in mice with SCD through improved cellular and functional outcomes, paving the way for new therapeutic strategies to handle ischemic injuries related to this debilitating condition.
Furthermore, we observed that SC411 helped decrease harmful arachidonic acid levels and reduced the sickling of red blood cells, thereby potentially alleviating some of the pain and complications associated with the disease. The treatment not only improved cerebral blood flow but also seemed to enhance cognitive functions, like memory, in the mice.
Overall, the results highlighted that treatment with SC411 could significantly enhance survival rates in mice with SCD through improved cellular and functional outcomes, paving the way for new therapeutic strategies to handle ischemic injuries related to this debilitating condition.
8.8
Helps with fatigue
Most Useful Review
This product is amazing and very helpful. I no longer feel fatigued, and it’s excellent for anaemia as it contains fish oil.
Arteriosclerosis
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
6.9
USERS' SCORE
Very Good
Based on 2 Reviews
7.9
8
Eicosapentaenoic acid benefits atherosclerosis
The effect of omega-3 polyunsaturated fatty acid intake on blood levels of omega-3s in people with chronic atherosclerotic disease: a systematic review.
Most Relevant Research
We set out to understand how eicosapentaenoic acid (a type of omega-3 fatty acid) influences blood levels in individuals suffering from chronic atherosclerotic disease. This study synthesized findings from 25 articles, focusing on randomized controlled trials that investigated omega-3 supplementation specifically for this patient group.
Our exploration revealed that dosages between 1.8 grams and 3.4 grams per day, over a span of three to six months, were effective in elevating omega-3 levels to therapeutic targets. Higher doses, at 4.4 grams or more, showed similar benefits even with a shorter supplementation period, ranging from one to six months.
The evidence suggests that regular omega-3 supplementation could be crucial for individuals with atherosclerosis, potentially improving their health outcomes and lowering cardiac risks. Given the study’s findings, we advocate for reassessing dietary recommendations and considering higher daily intake allowances for omega-3s in these patients.
Our exploration revealed that dosages between 1.8 grams and 3.4 grams per day, over a span of three to six months, were effective in elevating omega-3 levels to therapeutic targets. Higher doses, at 4.4 grams or more, showed similar benefits even with a shorter supplementation period, ranging from one to six months.
The evidence suggests that regular omega-3 supplementation could be crucial for individuals with atherosclerosis, potentially improving their health outcomes and lowering cardiac risks. Given the study’s findings, we advocate for reassessing dietary recommendations and considering higher daily intake allowances for omega-3s in these patients.
8.8
Stable health checkup
Most Useful Review
For managing arteriosclerosis, it’s best to control it through diet, although taking omega can be challenging. I have my husband, who has high triglyceride levels, take it daily. The capsules are somewhat large, but one can adapt to them. I have been taking it for many years, and as my health check-up results are stable, I will continue with it.
Back Pain
SCIENTIFIC SCORE
Most Likely Effective
Based on 7 Researches
7.4
USERS' SCORE
Very Good
Based on 6 Reviews
7.9
9
Eicosapentaenoic acid alleviates back pain
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Most Relevant Research
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
9.5
Joint pain relief
Most Useful Review
I drank two capsules each morning with breakfast for three weeks. I've noticed increased endurance during cardio workouts and no knee pain, which was a previous issue during lunges and squats. This product has worked well for me and my husband, with no mouth or stomach discomfort experienced. I highly recommend it!
Blood Clot
SCIENTIFIC SCORE
Most Likely Effective
Based on 15 Researches
7.6
USERS' SCORE
Very Good
Based on 8 Reviews
7.9
9
Eicosapentaenoic acid influences clotting
Emergence of omega-3 fatty acids in biomedical research.
Most Relevant Research
We explored how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences blood clotting processes. The interest in EPA grew substantially after the 1970s when researchers Dyerberg and Bang noted that Greenland Eskimos had lower rates of coronary disease linked to their diet rich in marine lipids.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
9.5
Headache relief
Most Useful Review
I have been taking Omega for four months now, and my body feels much better. My headaches and fluctuating blood pressure have disappeared. Previously, I used omega from two other brands, but this third one with a hint of lemon is my favourite. The jar is sturdy and lasts for about 75 days. I used to be sceptical about supplements, but this has genuinely improved my vascular health and eliminated the need for pressure medication since autumn. I am very pleased!
Irritable Bowel Syndrome
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Researches
5
USERS' SCORE
Very Good
Based on 3 Reviews
7.9
5
Fatty acids affect IBS metabolism
Bifidobacterium breve with α-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome.
Most Relevant Research
Our study focused on understanding how eicosapentaenoic acid, alongside other fatty acids, influences irritable bowel syndrome (IBS). We designed an experiment where we treated both maternally separated and non-separated rats with Bifidobacterium breve and explored its effect on colonic sensitivity and fatty acid metabolism over a period of seven weeks.
Throughout our research, we observed significant changes in fatty acid profiles, especially in liver and serum tissues, after administering Bifidobacterium breve. Notably, in the maternally separated rats, the treatment appeared to enhance levels of palmitoleic acid, arachidonic acid, and docosahexaenoic acid in various tissues, which are fatty acids that others believe could be influential in managing symptoms related to IBS.
However, while eicosapentaenoic acid was present in the research context, it was largely studied in combination with other treatments. This made it challenging to evaluate its isolated effect on IBS directly. Thus, while we noted some positive metabolic changes with our treatment approach, the specific impact of eicosapentaenoic acid on IBS symptoms wasn’t definitively established.
Overall, our findings suggest that while Bifidobacterium breve and fatty acid supplementation may influence host fatty acid metabolism, further focused studies are necessary to clarify the role of eicosapentaenoic acid in managing irritable bowel syndrome.
Throughout our research, we observed significant changes in fatty acid profiles, especially in liver and serum tissues, after administering Bifidobacterium breve. Notably, in the maternally separated rats, the treatment appeared to enhance levels of palmitoleic acid, arachidonic acid, and docosahexaenoic acid in various tissues, which are fatty acids that others believe could be influential in managing symptoms related to IBS.
However, while eicosapentaenoic acid was present in the research context, it was largely studied in combination with other treatments. This made it challenging to evaluate its isolated effect on IBS directly. Thus, while we noted some positive metabolic changes with our treatment approach, the specific impact of eicosapentaenoic acid on IBS symptoms wasn’t definitively established.
Overall, our findings suggest that while Bifidobacterium breve and fatty acid supplementation may influence host fatty acid metabolism, further focused studies are necessary to clarify the role of eicosapentaenoic acid in managing irritable bowel syndrome.
8.8
Metabolism enhancement
Most Useful Review
This is an excellent quality product with well-selected ingredients. I experienced no allergies, and the large package will last a long time. I began to notice better bowel function and improved metabolism within a week. My nervous system started to perform better too, which made me feel less anxious. I have complete confidence in its effectiveness.
Acne
SCIENTIFIC SCORE
Most Likely Effective
Based on 24 Researches
7.2
USERS' SCORE
Very Good
Based on 10 Reviews
7.8
8
Omega-3 may improve acne
Acne and diet: a review.
Most Relevant Research
We observed that acne is a common skin condition, particularly affecting individuals under 30. Our exploration into the role of diet revealed that nutrition significantly influences acne development. Among the various dietary components, omega-3 fatty acids stood out due to their potential anti-inflammatory properties.
The research indicates that foods rich in omega-3 can help reduce the production of inflammatory substances that may contribute to acne. Additionally, specific fatty acids, such as docosapentaenoic acid and γ-linolenic acid, have shown promise in improving acne lesions.
By integrating omega-3 into the diet, we might be able to mitigate some of the troublesome symptoms associated with acne. While the evidence is still unfolding, the link between omega-3 fatty acids and reduced acne severity offers a hopeful avenue worth considering for those battling breakouts.
The research indicates that foods rich in omega-3 can help reduce the production of inflammatory substances that may contribute to acne. Additionally, specific fatty acids, such as docosapentaenoic acid and γ-linolenic acid, have shown promise in improving acne lesions.
By integrating omega-3 into the diet, we might be able to mitigate some of the troublesome symptoms associated with acne. While the evidence is still unfolding, the link between omega-3 fatty acids and reduced acne severity offers a hopeful avenue worth considering for those battling breakouts.
8.8
Skin quality improvement
Most Useful Review
I first purchased fish oil for its cost-effectiveness and lemon flavour. I was pleasantly surprised by how comfortable I felt and noticed an improvement in my skin quality, which had been prone to acne due to my meat-heavy diet. The subtle lemon aroma made it easy to consume, and the packaging is appealing. It seems to be an essential supplement for me.
Dizziness
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 3 Reviews
7.8
8.8
Dizziness addressed
Most Useful Review
After years of reliance on medications for sleep, I found this product excellent. After six months, I recommend taking 5mg or 3mg for sleep; it works well and suits morning people. If you drink coffee, 10mg is suitable but may cause slight dizziness and sleepiness initially. That feeling fades after some time.
Heart Attack
SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.9
USERS' SCORE
Very Good
Based on 26 Reviews
7.6
9
Eicosapentaenoic acid aids heart recovery
Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats.
Most Relevant Research
We investigated how eicosapentaenoic acid (EPA) may help improve heart health after a heart attack. In our study, we induced myocardial infarction (MI) in male rats by ligating their coronary artery. Some of these rats received daily treatment with EPA, while others did not, allowing us to compare the effects.
Over 12 weeks, we observed that the rats treated with EPA showed better left ventricular function—essentially, their hearts were working more efficiently. Moreover, these rats had higher levels of EPA in their mitochondria, which are the energy factories of cells. Despite the damage caused by the heart attack, the EPA treatment helped maintain crucial energy levels and kept the mitochondrial function from declining, preserving a specific protein linked to cellular health.
Our findings suggest that including EPA in the diet can bolster mitochondrial quality and support heart function after an MI. This could mean that EPA may serve as an important dietary addition for promoting heart health following heart events.
Over 12 weeks, we observed that the rats treated with EPA showed better left ventricular function—essentially, their hearts were working more efficiently. Moreover, these rats had higher levels of EPA in their mitochondria, which are the energy factories of cells. Despite the damage caused by the heart attack, the EPA treatment helped maintain crucial energy levels and kept the mitochondrial function from declining, preserving a specific protein linked to cellular health.
Our findings suggest that including EPA in the diet can bolster mitochondrial quality and support heart function after an MI. This could mean that EPA may serve as an important dietary addition for promoting heart health following heart events.
9.5
Heart health support
Most Useful Review
Value Pack Omega-3 Fish Oil helps support heart and brain health, and maintains healthy triglyceride levels. It's molecularly distilled to remove harmful substances. Some studies suggest omega-3 may reduce heart attack risk.
Knee Pain
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
6.8
USERS' SCORE
Very Good
Based on 14 Reviews
7.6
8
Eicosapentaenoic acid alleviates knee pain
l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Most Relevant Research
We explored the potential benefits of eicosapentaenoic acid (EPA) combined with l-serine in relieving chronic low-back and knee pain among adults. In a well-structured randomized, double-blind, placebo-controlled trial, we followed 120 participants who suffered from pain for over three months. They were divided into two groups: one received daily doses of 594 mg of l-serine and 149 mg of EPA, while the other group was given a placebo.
After eight weeks of treatment and a four-week follow-up, we observed pain relief improvements reported through various questionnaires. The results indicated that the combination of l-serine and EPA was effective in reducing pain in the lower back and knees, highlighting the significance of these components in managing chronic pain conditions. Though EPA was part of a combination treatment, its anti-inflammatory properties may offer a promising avenue for individuals suffering from knee pain specifically.
Our findings provide an encouraging perspective for those seeking alternatives for pain management. While the study combined l-serine with EPA, it became evident that these ingredients together can lead to meaningful relief for patients with persistent knee pain.
After eight weeks of treatment and a four-week follow-up, we observed pain relief improvements reported through various questionnaires. The results indicated that the combination of l-serine and EPA was effective in reducing pain in the lower back and knees, highlighting the significance of these components in managing chronic pain conditions. Though EPA was part of a combination treatment, its anti-inflammatory properties may offer a promising avenue for individuals suffering from knee pain specifically.
Our findings provide an encouraging perspective for those seeking alternatives for pain management. While the study combined l-serine with EPA, it became evident that these ingredients together can lead to meaningful relief for patients with persistent knee pain.
9.5
No knee pain
Most Useful Review
I drink these capsules with my husband every morning alongside breakfast. After three weeks, I've noticed improved endurance during cardio workouts, and intriguingly, I experienced no knee pain during squats and lunges that previously caused discomfort. No stomach issues either! I hope my review helps others.
Cold Sores
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 2 Reviews
7.3
9.5
Effective treatment
Most Useful Review
Works! My skin was very dry, and I frequently suffered from cold sores. Along with vitamin D, these capsules addressed my issues, and my hair also improved. It works 100%, I highly recommend it for health!
Bloating
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.9
9.5
No bloating here
Most Useful Review
Excellent! A good omega-3 supplement that is easy to take and does not cause bloating. It is essential for managing cholesterol levels.
Diarrhea
SCIENTIFIC SCORE
Most Likely Effective
Based on 7 Researches
7.4
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.7
8
5,6-DiHETE alleviates diarrhea
Efficient Attenuation of Dextran Sulfate Sodium-Induced Colitis by Oral Administration of 5,6-Dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic Acid in Mice.
Most Relevant Research
We examined how eicosapentaenoic acid, specifically a compound called 5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid (5,6-DiHETE), affects diarrhea caused by inflammation in mice. In our study, the mice were given a substance that induces colitis, known as dextran sulfate sodium (DSS), and then treated with different doses of 5,6-DiHETE orally.
What we found was promising: the administration of both 150 and 600 micrograms of 5,6-DiHETE daily helped to speed up the recovery from diarrhea. After just a few days of treatment, we observed significant improvements in the mice’s condition. The daily doses led to less inflammation in the colon and a notable reduction in the symptoms of diarrhea associated with DSS-induced colitis.
We also measured how much of this compound remained in the mice's blood after taking it, finding that it peaked within half an hour of administration. This suggests that 5,6-DiHETE works relatively quickly to start affecting the inflammation. Overall, our research indicates that eicosapentaenoic acid holds potential as a beneficial treatment for inflammatory bowel diseases that cause diarrhea.
What we found was promising: the administration of both 150 and 600 micrograms of 5,6-DiHETE daily helped to speed up the recovery from diarrhea. After just a few days of treatment, we observed significant improvements in the mice’s condition. The daily doses led to less inflammation in the colon and a notable reduction in the symptoms of diarrhea associated with DSS-induced colitis.
We also measured how much of this compound remained in the mice's blood after taking it, finding that it peaked within half an hour of administration. This suggests that 5,6-DiHETE works relatively quickly to start affecting the inflammation. Overall, our research indicates that eicosapentaenoic acid holds potential as a beneficial treatment for inflammatory bowel diseases that cause diarrhea.
8.8
No bad breath
Most Useful Review
It tastes excellent, does not cause bad breath, and I’ve not experienced any diarrhoea.
Constipation
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.1
9.5
Constipation relief
Most Useful Review
Fish oil is remarkable. Anyone suffering from constipation will quickly appreciate the benefits it offers.
