Natrol Omega-3

EPA significantly reduces migraine frequency

Based on 23 Researches

Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. doi:10.1016/j.bbi.2024.03.019

We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.

Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.

Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.

Migraine relief

Most Useful Review

Taking these capsules regularly has normalised my sleep and significantly improved my migraines. When I feel symptoms starting, I take my pills, add extra magnesium, and my migraine typically subsides within hours, compared to previously being incapacitated for half a day. My PMS and menstruation have also become much more manageable with regular magnesium intake, and my chronic nasopharynx pain has lessened. I've also been taking omega-3 and other supplements, which may contribute. I've experienced no side effects; the quality is excellent and natural.

Arteriosclerosis details

Chong SY, Wang X, van Bloois L, Huang C, Syeda NS, et al. Injectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability. J Control Release. 2023;360:344. doi:10.1016/j.jconrel.2023.06.035

Based on 25 Researches

DHA stabilizes arterial plaques

We embarked on a quest to understand how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, can impact atherosclerosis, a condition where fatty deposits clog the arteries. Our focus was on a specially developed injectable formulation that delivers DHA directly to the site of arterial plaques.

Through our research, we discovered that this liposomal DHA formulation not only protects the compound but also enhances its effectiveness. When we administered it intravenously, DHA particles were specifically absorbed by macrophages—immune cells involved in the inflammation seen in atherosclerosis. This targeted delivery helps reduce inflammation and prevents the formation of foam cells, which are a hallmark of atherosclerotic plaques.

Furthermore, our analysis of the plaques revealed that the DHA treatment led to less macrophage infiltration and reduced lipid build-up, which improves overall plaque stability. In simpler terms, we observed that the treatment makes plaques less likely to rupture, which is critical in preventing serious cardiovascular problems. Additionally, sophisticated imaging techniques showed that DHA can help restore some of the healthy lipid profiles typical of earlier stages of plaque development.

In summary, using injectable DHA offers exciting potential for stabilizing arterial plaques and slowing down the progression of atherosclerosis. Given the importance of addressing this condition, our findings could pave the way for new therapeutic strategies to reduce the risk of heart-related issues.

Risk reduction noted

Most Useful Review

It reduces the risk of arteriosclerosis and assists in maintaining healthy triglyceride levels.

Asthma details

Eicosapentaenoic acid improves asthma

Based on 24 Researches

Olave CJ, Ivester KM, Couetil LL, Burgess J, Park JH, et al. Effects of low-dust forages on dust exposure, airway cytology, and plasma omega-3 concentrations in Thoroughbred racehorses: A randomized clinical trial. J Vet Intern Med. 2023;37:338. doi:10.1111/jvim.16598

We compared how different types of forage affected asthma in Thoroughbred racehorses. Our focus was on assessing dust exposure, airway health, and the presence of eicosapentaenoic acid (EPA), an omega-3 fatty acid known for its anti-inflammatory properties. The horses were randomly assigned to three diets: dry hay, steamed hay, or haylage for a period of six weeks.

Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.

In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.

Asthma risk reduction

Most Useful Review

This supplement is remarkable. It can help reduce the risk of asthma in children when mothers take fish oil. It also offers numerous other benefits, including improved metabolic rate and support for various health issues, such as rheumatoid arthritis and depression.

Common Cold details

Imhoff-Kunsch B, Stein AD, Martorell R, Parra-Cabrera S, Romieu I, et al. Prenatal docosahexaenoic acid supplementation and infant morbidity: randomized controlled trial. Pediatrics. 2011;128:e505. doi:10.1542/peds.2010-1386

Based on 3 Researches

DHA reduces infant cold symptoms

We conducted a double-blind randomized controlled trial to understand how prenatal supplementation of docosahexaenoic acid (DHA) might influence infant health, particularly concerning the common cold. Pregnant women were given either a daily dose of 400 mg of DHA or a placebo starting at 18 to 22 weeks of gestation until childbirth.

Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.

While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.

Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.

This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.

Effective for colds

Most Useful Review

6 people found this helpful

Works! My skin was extremely dry, and I suffered from frequent cold sores. However, alongside vitamin D, these capsules have alleviated my issues. My hair also appears healthier now! They work effectively, and I recommend them for health improvements!

We aimed to understand how eicosapentaenoic acid (EPA) affects psoriasis, a skin condition known for causing redness, irritation, and thickened skin. By creating skin models that reflect both healthy and psoriatic conditions, we were able to assess the impact of EPA directly on lipid profiles—a key factor in skin health.

Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.

More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.

Nutritional support

Most Useful Review

Omega-3 polyunsaturated fatty acids (PUFAs) are increasingly recognised for psoriasis. They not only aid in medication but also provide essential nutritional support. DHA and EPA in Omega-3 help stabilise immune functions, leading to reduced inflammation and fewer relapses in psoriasis.

Swollen Lymph Nodes details

Miraculous skin improvement

Most Useful Review

3 people found this helpful

I started taking Omega-3 on the recommendation of my endocrinologist due to my AIT and hypothyroidism. My skin, particularly on my face, elbows, and knees, was extremely dry and sensitive, often feeling tight and swollen. I tried various creams, but they caused allergic reactions. However, about a month after I began taking Omega-3, I noticed a significant improvement; my skin only dried out after washing, and now I can skip cream for two days without discomfort. This has been a miracle for me! Initially, I took one capsule twice a day, but when I switched to Finnish Omega, the results worsened. I plan to reorder this Omega as the large capsules are worth it. I highly recommend it!

Yeast Infection details

Moderately Effective

Eicosapentaenoic acid combats yeast biofilms

Wang S, Xie S, Li T, Liu J, Wang P, et al. Eicosapentaenoic acid as an antibiofilm agent disrupts mature biofilms of . Biofilm. 2025;9:100251. doi:10.1016/j.bioflm.2024.100251

We set out to explore how eicosapentaenoic acid (EPA), a type of healthy fat, can disrupt the mature biofilms formed by a significant human fungal pathogen. These biofilms are important since they enhance the pathogen's ability to cause infections. Our investigation focused on the effects of a 1 mM EPA treatment on these established biofilms.

Through various assays, we observed that EPA significantly reduced the viability of these preformed biofilms. The use of advanced microscopy techniques allowed us to see that EPA could block the transformation from yeast to a more invasive form and damaged the biofilm's structure.

We also found that EPA prompted changes at the genetic level. Specifically, it downregulated genes linked to the development of hyphae and biofilms. Additionally, EPA affected two key signaling pathways involved in biofilm formation. Notably, it reduced the production of a crucial messenger in one of these pathways.

Lastly, we noted that treatment with EPA downregulated genes related to ergosterol biosynthesis, suggesting it may lower the chances of developing resistance to existing antifungal treatments. Our findings emphasize the potential of EPA as a promising alternative or complementary option in treating yeast infections.

Promotes hair growth

Most Useful Review

Hair grows quite remarkably, almost like a yeast infection. I suggest giving it a try.

Diabetes details

Sugasini D, Yalagala PCR, Park JC, Ma G, Farooq Z, et al. Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2024;65:39. doi:10.1167/iovs.65.14.39

Based on 16 Researches

Reduced retina DHA in diabetes

We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.

Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.

Supports heart and brain health

Most Useful Review

Omega-3 fatty acids are vital for beauty, youth, and health. They reduce heart disease risk, enhance blood circulation, cognitive functions, and lower blood pressure, making them useful in diabetes prevention. Natrol Omega aids in maintaining healthy triglyceride levels. Recommended dosage is one softgel twice daily with meals.

Hypertension details

Eicosapentaenoic acid benefits hypertension

Based on 28 Researches

Asulin M, Gorodetzer N, Fridman R, Shelly Ben-Shushan R, Cohen Z, et al. 5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway. Biochem Biophys Res Commun. 2024;700:149585. doi:10.1016/j.bbrc.2024.149585

We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.

Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.

Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.

Effective against hypertension

Most Useful Review

Omega-3 Fish Oil works brilliantly! I prescribe it to my patients with cardiovascular issues, including hypertension and arrhythmias. It's important to remember that individuals may have a specific intolerance to the components of the medication.

Hypothyroidism details

Abd Allah ES, Gomaa AM, Sayed MM. The effect of omega-3 on cognition in hypothyroid adult male rats. Acta Physiol Hung. 2014;101:362. doi:10.1556/APhysiol.101.2014.3.11

Based on 11 Researches

Omega-3 aids hypothyroid cognition

We set out to investigate how hypothyroidism affects cognitive function and whether omega-3 could provide a helpful boost in adult male rats. The study involved thirty rats, split into three groups: one as a control, another experiencing hypothyroidism, and the last group receiving omega-3 treatment.

The findings were quite striking. Rats with induced hypothyroidism showed significant memory problems, including difficulties in spatial learning and retention in various tests. These deficits were accompanied by lower levels of important brain chemicals and noticeable structural damage in the hippocampus, a key area for memory.

However, when we provided omega-3 supplements to one group, there was a remarkable turnaround. Those rats not only saw improvements in their memory but also regained some brain health. Omega-3 helped boost antioxidant levels, lessen structural issues in the brain, and reduce the expression of a protein linked to these damages.

All in all, our research suggests that omega-3 may serve as a protective ally against the cognitive challenges posed by hypothyroidism. This offers an exciting avenue for potential treatments that could benefit not just rats but perhaps humans facing similar hormonal challenges.

Miraculous skin improvement

Most Useful Review

3 people found this helpful

My first omega-3, recommended by my endocrinologist, needed for my hypothyroidism. Initially, my skin was extremely dry and sensitive, but after taking Omega for about a month, I noticed a significant improvement. My skin now remains better hydrated even after washing. I take two capsules daily after meals. I previously tried Finnish and Norwegian omega, but I prefer this one, despite the large capsule size. Highly recommend it!

Arthritis details

Omega-3 benefits joint health in RA

Based on 37 Researches

Wang W, Xu Y, Zhou J, Zang Y. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Clin Rheumatol. 2024;43:2479. doi:10.1007/s10067-024-07040-0

We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.

However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels.

Joint health

Most Useful Review

8 people found this helpful

Fish oil is beneficial for the brain and boosts the immune system. It lowers blood pressure and improves joint mobility, which is vital for those suffering from arthritis. My therapist recommended it to stabilise my cholesterol. This is a high-quality product at a reasonable price. Our family takes it daily, and we notice no side effects. Highly recommended for everyone!

Cancer details

Omega-3 diet slows cancer progression

Aronson WJ, Grogan T, Liang P, Jardack P, Liddell AR, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43:800. doi:10.1200/JCO.24.00608

We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression.

In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management.

7.5

Cancer prevention benefits

Most Useful Review

33 people found this helpful

"Mega" omega is wonderful fish oil of excellent quality! It contains a natural fish oil concentrate rich in polyunsaturated fatty acids, which dramatically lower cholesterol levels, supporting cardiovascular health. Omega 3 is noted for slowing tumour development and is effective in preventing cancer. It aids in skin disease treatment and improves healing. This supplement also normalises digestion and fat metabolism, alleviates arthritis pain, and is essential for brain activity. Recommended dosage is 3-4 capsules daily with meals.

Chest Pain details

Mizia-Stec K, Mizia M, Haberka M, Lasota B, Gieszczyk-Strózik K, et al. N-3 polyunsaturated fatty acids do not influence the efficacy of dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention. Cardiol J. 2013;20:478. doi:10.5603/CJ.2013.0132

Based on 17 Researches

Omega-3 fish oil ineffective

We examined whether taking omega-3 fatty acids could enhance the effects of dual antiplatelet therapy for patients dealing with stable angina after heart procedures. Our study involved 40 patients who were split into two groups: one received omega-3 alongside standard medication, while the other did not.

After testing platelet activity over time, we found no significant differences between the two groups. This suggests that omega-3 fish oil does not provide additional benefits for managing chest pain in these patients.

No chest pain

Most Useful Review

8 people found this helpful

I take 2 capsules each morning with breakfast. After 3 weeks, I've noticed improved endurance during cardio workouts, and for the first time, I have no knee pain, which used to trouble me during lunges and squats. I experienced some mouth and stomach discomfort previously, but now, everything is excellent!

Chronic Fatigue Syndrome details

Eicosapentaenoic acid shows potential

Based on 5 Researches

Puri BK. The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids. 2004;70:399.

We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.

These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.

Eliminated fatigue

Most Useful Review

6 people found this helpful

Works! My skin was excessively dry, and I was often fatigued and suffering from cold sores. Since taking these capsules alongside vitamin D, my issues have been resolved, and my hair appears healthier. It truly works, and I wholeheartedly recommend it for addressing chronic fatigue syndrome!

Cold details

6 people found this helpful

Works!!! My skin was very dry, I experienced fatigue, and I frequently had cold sores on my lips. These capsules, combined with vitamin D, have resolved my issues, and my hair has visibly improved! It works 100%—here’s to health!

Flu details

I will take more Omega 3, the most beneficial vitamin. Thanks to it, I can enhance my mental and physical wellbeing. Supplements should be consumed in late autumn and early spring when the immune system is weakened. My diet includes foods rich in fish oil during outbreaks of SARS, flu, and other infectious diseases. It is convenient to use, has no side effects, and my skin feels hydrated and nourished.

Hair Loss details

Omega-3 improves women's hair density

Likely Very Effective

Le Floc'h C, Cheniti A, Connétable S, Piccardi N, Vincenzi C, et al. Effect of a nutritional supplement on hair loss in women. J Cosmet Dermatol. 2015;14:76. doi:10.1111/jocd.12127

We examined the effects of a 6-month supplementation of omega 3 and 6, along with antioxidants, on women's hair loss. In this randomized study involving 120 healthy participants, improvements in hair density were objectively measured through photographs.

The results showed significant reductions in hair loss, with 89.9% of women reporting decreased loss and improved hair thickness and density. This suggests omega 3 and 6 can be effective allies against hair loss in women, as confirmed by both objective measurements and personal experiences.

Restored hair growth

Most Useful Review

After taking these, my hair growth was restored, hair loss stopped, and my hair became vibrant and shiny.

Headache details

EPA shows promise for migraine relief

Based on 20 Researches

We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.

Headache relief

Most Useful Review

4 people found this helpful

I've been taking Omega for four months, and it has greatly improved my blood vessel health and eliminated my headaches. This Omega has a pleasant lemon flavour, and I find the quantity sufficient for my needs. I was sceptical about dietary supplements, but I no longer need medication for pressure issues, and I'm genuinely pleased with the results.

Insomnia details

Eicosapentaenoic acid shows limited benefits

Watanabe N, Matsuoka Y, Kumachi M, Hamazaki K, Horikoshi M, et al. Omega-3 fatty acids for a better mental state in working populations - Happy Nurse Project: A 52-week randomized controlled trial. J Psychiatr Res. 2018;102:72. doi:10.1016/j.jpsychires.2018.03.015

We explored the effectiveness of eicosapentaenoic acid, a type of omega-3 fatty acid, on insomnia among junior hospital nurses in a well-structured trial. In this study, 80 nurses were randomly assigned to receive either 1200 mg of eicosapentaenoic acid along with 600 mg of docosahexaenoic acid daily or a placebo for 13 weeks.

Our main focus was to see how these supplements influenced insomnia and overall mental health. While we noted some improvements in various measures, including insomnia severity at the 13-week mark, the results didn't demonstrate a significant advantage when compared to the placebo group.

After analyzing data at multiple checkpoints—13, 26, and 52 weeks—we found that the effects of eicosapentaenoic acid on insomnia were not strong enough to conclude it as a beneficial treatment. Overall, while there were some positive indicators at certain times, the overall impact on insomnia was not substantial, leaving us to conclude that more research is needed to confirm any real benefits from omega-3 fatty acids for sleep disturbances.

Effective for insomnia

Most Useful Review

My husband suffers from insomnia, and the doctor recommended 1000 mg. It has helped him significantly, for which we are grateful.

Menopause details

Gao H, Ying Y, Sun J, Huang Y, Li X, et al. Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16234103

Based on 31 Researches

Omega-3 links to menopause timing

We investigated the link between omega-3 fatty acids and the timing of menopause. Using a Mendelian randomization approach, we analyzed data from thousands of women to assess how different fatty acids influenced reproductive longevity—specifically, the age at menopause.

Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.

7.5

Menopause relief

Most Useful Review

9 people found this helpful

The condition of my skin and hair has improved. Omega-3 PUFAs, which the body cannot synthesise, are essential for various functions. They are particularly important for women during menopause, helping alleviate its symptoms, and reducing menstrual pain. I've noticed a positive effect on my digestive tract as well. After two to three weeks of taking two capsules daily, I experienced noticeable improvements. I will continue this as a preventive measure for my health and well-being.

Premenstrual Syndrome details

This product effectively helps during premenstrual syndrome. I appreciate that there is no fishy smell, especially as I’ve ordered it multiple times and intend to continue doing so.

Alzheimer details

Otaegui L, Urgin T, Zaiter T, Zussy C, Vitalis M, et al. Nose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease. Int J Pharm. 2025;670:125125. doi:10.1016/j.ijpharm.2024.125125

Based on 29 Researches

DHA shows promise in Alzheimer's

We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.

The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.

Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients.

Memory support

Most Useful Review

Omega-3 is crucial for preventing Alzheimer's and supporting heart health. I take 2 capsules daily and have also tried a higher dosage. This product is effective, with no fishy aftertaste and a pleasant lemon flavour.

Anemia details

Wang H, Shi P, Huang C, Liu Q. Maresin 1 ameliorates iron-deficient anemia in IL-10(-/-) mice with spontaneous colitis by the inhibition of hepcidin expression though the IL-6/STAT3 pathway. Am J Transl Res. 2016;8:2758.

Based on 20 Researches

Maresin 1 helps treat anemia

We focused on how Maresin 1, a compound derived from docosahexaenoic acid, might help improve iron-deficient anemia in mice with chronic colitis. Our research involved IL-10 knockout mice, which are known to develop spontaneous colitis and associated anemia.

Over two weeks, we treated these mice with MaR1, observing several important changes. We found that MaR1 significantly reduced inflammation in the colon and was associated with a boost in hemoglobin levels, increased serum iron, and improved transferrin saturation.

Additionally, we noted that the levels of hepcidin, a protein that regulates iron metabolism and is often elevated during inflammation, decreased after treatment. This suggests that MaR1 helps combat anemia by influencing this protein's expression through the IL-6/STAT3 pathway.

Overall, we uncovered promising evidence that MaR1 has the potential to alleviate anemia connected to inflammatory processes, making it a noteworthy area for further exploration in treating patients with similar conditions.

7.5

Helps with fatigue

Most Useful Review

This product is amazing and very helpful. I no longer feel fatigued, and it’s excellent for anaemia as it contains fish oil.

Anxiety details

Omega-3s improve mental health outcomes

Based on 26 Researches

Li Y, Hua L, Ran Q, Gu J, Bao Y, et al. Plasma Polyunsaturated Fatty Acid Levels and Mental Health in Middle-Aged and Elderly Adults. Nutrients. 2024;16. doi:10.3390/nu16234065

We explored the impact of polyunsaturated fatty acids (PUFAs), particularly omega-3s, on anxiety and depression in over 102,000 participants from the UK Biobank.

The study revealed that higher levels of omega-3 PUFAs were linked to lower risks of developing anxiety and depressive disorders, alongside improvement in adverse psychological symptoms.

Additionally, the research highlighted significant associations between these fatty acids and brain white matter structure, providing valuable insights into how omega-3s might support mental wellness.

7.5

Reduces anxiety effectively

Most Useful Review

4 people found this helpful

Excellent Omega. This is one of my favourites. Omega-3 supplementation has helped me with my anxiety and overall well-being. I find it easier to obtain essential fatty acids through supplements rather than consuming fatty fish regularly. I take 1-2 capsules daily with breakfast, and I believe Omega-3 is essential for my health. It supports blood vessel health and overall cardiovascular system functionality, making it good value for money.

Nausea details

Cerchietti LC, Navigante AH, Castro MA. Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Nutr Cancer. 2007;59:14.

Based on 4 Researches

Omega-3s show symptom relief

We aimed to see how omega-3 fatty acids from fish oil could ease nausea and other symptoms in patients with advanced lung cancer suffering from Systemic Immune-Metabolic Syndrome (SIMS). The study involved a small group of patients divided into treatment groups, some receiving fish oil and others a combination of fish oil with celecoxib.

After six weeks, we noted improvements in appetite, fatigue, and lower inflammation markers in both fish oil groups. Interestingly, those who received fish oil alongside celecoxib showed even greater benefits in weight gain and muscle strength. These findings suggest that fish oil may help manage certain symptoms associated with nausea but not specifically reduce it alone.

No nausea noted

Most Useful Review

8 people found this helpful

Good budget omega. Natrol has produced quality supplements for 35 years. Their omega-3s are from fish muscles, molecularly distilled to remove impurities. The capsules have a light lemon aroma. Although not the smallest, they are easy to swallow. I take them morning and evening. I experienced no side effects, including nausea. Omega-3 helped normalise my cholesterol a few years ago. I take it in courses and have noticed benefits for my skin as well, particularly on my elbows and hands.

Sleep Apnea details

Moderately Effective

Yokoi-Shimizu K, Yanagimoto K, Hayamizu K. Effect of Docosahexaenoic Acid and Eicosapentaenoic Acid Supplementation on Sleep Quality in Healthy Subjects: A Randomized, Double-Blinded, Placebo-Controlled Trial. Nutrients. 2022;14. doi:10.3390/nu14194136

Omega-3s enhance sleep quality

We investigated how omega-3 fatty acids, specifically DHA and EPA, affect sleep quality in adults aged 45 and older. Our study involved 66 healthy participants and employed a randomized, double-blind, placebo-controlled design for 12 weeks.

Participants in the DHA/EPA group showed significant improvements in sleep quality metrics, including less frequent dreaming and better sleep efficiency compared to those taking a placebo. This is notable as it provides new insights about the beneficial effects of omega-3s on sleep in an older demographic.

Supports sleep issues

Most Useful Review

1 people found this helpful

Omega-3 fatty acids are essential for everyone. A deficiency can lead to skin issues, concentration loss, sleep disturbances, irritability, chronic fatigue, and worsened allergy reactions. This product has improved my heart function, as well as my skin and hair. They are easy to swallow. I take two capsules daily with food.

Blurred Vision details

Boosts memory function

Most Useful Review

2 people found this helpful

The best omega with lemon flavour! It is excellent for vision, brain function, and nervous system support. I highly recommend it!

Bone Pain details

Resolvin D1 alleviates bone cancer pain

Likely Very Effective

Flippen A, Khasabova IA, Simone DA, Khasabov SG. Systemic administration of Resolvin D1 reduces cancer-induced bone pain in mice: Lack of sex dependency in pain development and analgesia. Cancer Med. 2024;13:e70077. doi:10.1002/cam4.70077

We explored the potential of Resolvin D1 (RvD1) as a non-opioid treatment for bone cancer pain in a mouse model. RvD1 was administered intravenously, showing a remarkable ability to lessen pain effects similarly in both male and female mice.

We found that a single dose effectively reduced pain, while daily treatments eliminated it entirely. Notably, sex didn't influence the pain or treatment efficacy, opening doors for RvD1 as a viable alternative to opioids in managing bone cancer pain.

No knee pain

Most Useful Review

8 people found this helpful

I take 2 capsules each morning with breakfast, and I've noticed greater endurance during cardio workouts. My knees, which formerly experienced bone pain during lunges and squats, feel perfectly fine now. There are no lingering issues whatsoever. I haven’t encountered any mouth or stomach discomfort, so I rate this as EXCELLENT!

Cold Sores details

6 people found this helpful

Works! My skin was very dry, and I frequently suffered from cold sores. Along with vitamin D, these capsules addressed my issues, and my hair also improved. It works 100%, I highly recommend it for health!

Depression details

Wu SK, Yang KJ, Liu WC, Malau IA, Zailani H, et al. The Efficacy of Omega-3 Fatty Acids as the Monotherapy for Depression: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Nutrients. 2024;16. doi:10.3390/nu16213688

Based on 30 Researches

Omega-3 fatty acids show promise

We conducted a study to see if omega-3 fatty acids could help people with major depressive disorder as a standalone treatment. Over 12 weeks, 60 participants took either omega-3 supplements or a placebo.

Results showed that those taking omega-3 had lower depression scores at various points throughout the study. While there were hints of improved outcomes in terms of remission and response rates, these weren't statistically significant.

Overall, omega-3 fatty acids could be a promising alternative, but further research is necessary to confirm their effectiveness.

Depression relief

Most Useful Review

9 people found this helpful

This brand of fish oil has helped lift my permanent depression. There's no unpleasant fish taste or odour, and it works well compared to other Omega-3 brands I've tried.

Eczema details

Eicosapentaenoic Acid reduces eczema

Based on 20 Researches

Mirrahimi B, Moazemi M, Eslami N, Jamshidi E, Mir M, et al. Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial. J Pediatr Pharmacol Ther. 2023;28:29. doi:10.5863/1551-6776-28.1.29

We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.

Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.

Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.

7.5

Improved eczema condition

Most Useful Review

1 people found this helpful

I recommend this product! The capsules are large, as most omega-3s are. My husband took them alongside vitamin D, which significantly improved his dry eczema.

Knee Pain details

Torres-Guzman AM, Morado-Urbina CE, Alvarado-Vazquez PA, Acosta-Gonzalez RI, Chávez-Piña AE, et al. Chronic oral or intraarticular administration of docosahexaenoic acid reduces nociception and knee edema and improves functional outcomes in a mouse model of Complete Freund's Adjuvant-induced knee arthritis. Arthritis Res Ther. 2014;16:R64. doi:10.1186/ar4502

Based on 18 Researches

DHA reduces knee pain and swelling

We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.

This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.

No knee pain

Most Useful Review

8 people found this helpful

I drink these capsules with my husband every morning alongside breakfast. After three weeks, I've noticed improved endurance during cardio workouts, and intriguingly, I experienced no knee pain during squats and lunges that previously caused discomfort. No stomach issues either! I hope my review helps others.

Osteoporosis details

Li L, Wen Y, Liu D, Lan JP, Yang B. Causal link between docosahexaenoic acid and osteoporosis: A 2-sample Mendelian randomization study. Medicine (Baltimore). 2024;103:e38893. doi:10.1097/MD.0000000000038893

Based on 35 Researches

DHA linked to osteoporosis risk

We examined the relationship between docosahexaenoic acid (DHA) and osteoporosis using a method called 2-sample Mendelian randomization. This approach allowed us to investigate if higher levels of DHA could be a risk factor for osteoporosis.

Our findings revealed a causal tie: increased blood levels of DHA were indeed linked to a higher risk of developing osteoporosis. Specifically, for each standard deviation increase in DHA levels, the risk for osteoporosis rose by nearly 10%. We found this connection to be statistically significant, with a P-value of 0.033.

However, it's important to point out that the genetic correlation between DHA and osteoporosis was weak, suggesting that this relationship might not be heavily influenced by our genes. While these results indicate that DHA levels are a risk factor for osteoporosis, the underlying mechanisms are still unclear, highlighting the need for further research in this area.

7.5

Supports joint health

Most Useful Review

2 people found this helpful

Omega-3s support joint health and help prevent osteoporosis. They reduce inflammation and fight bone loss, alleviating joint pain, and mitigate symptoms of rheumatoid arthritis while slowing cartilage degradation in arthrosis. The fish oil is of high quality with no side effects like heartburn. I take it regularly and find it excellent value for money.

Irritable Bowel Syndrome details

Linsalata M, Ignazzi A, D'Attoma B, Riezzo G, Mallardi D, et al. Relationship between Markers of Gut Barrier Function and Erythrocyte Membrane PUFAs in Diarrhea-Predominant IBS Patients Undergoing a Low-FODMAP Diet. Nutrients. 2024;16. doi:10.3390/nu16162706

USERS' SCORE

Good

Based on 3 Reviews

Omega-3 benefits IBS-D gut health

We examined how omega-3 fish oil relates to gut health in patients with diarrhea-predominant irritable bowel syndrome (IBS-D). This involved studying 38 individuals who started a low-FODMAP diet for 12 weeks.

Initially, those with a compromised gut barrier displayed lower omega-3 levels. Post-diet, improvements were noted, with higher omega-3 levels and better gut function. This suggests that omega-3 fatty acids play a crucial role in enhancing gut integrity and may aid in managing IBS-D symptoms.

7.5

Metabolism enhancement

Most Useful Review

This is an excellent quality product with well-selected ingredients. I experienced no allergies, and the large package will last a long time. I began to notice better bowel function and improved metabolism within a week. My nervous system started to perform better too, which made me feel less anxious. I have complete confidence in its effectiveness.

Rheumatoid Arthritis details

Based on 16 Researches

Omega-3 shows potential benefits

We examined the effects of omega-3 supplementation on rheumatoid arthritis through a meta-analysis of 18 randomized controlled trials involving over 1,000 patients.

Our findings showed that omega-3 increased beneficial fatty acids and decreased triglyceride levels and tender joint counts.

However, while there were some reductions in inflammation markers, these changes weren't statistically significant, suggesting that omega-3 might not drastically alter disease activity overall.

7.5

Excellent supplement

Most Useful Review

Excellent! Omega-3 fatty acids help prevent osteoporosis and maintain joint health while alleviating pain during flare-ups. They fight bone loss, reduce inflammation, and help lessen the symptoms of rheumatoid arthritis, slowing the process of cartilage destruction during arthrosis.

Back Pain details

Eicosapentaenoic acid alleviates back pain

Based on 9 Researches

Lin Z, Ni L, Teng C, Zhang Z, Wu L, et al. Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis. Front Cell Dev Biol. 2021;9:745621. doi:10.3389/fcell.2021.745621

We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.

Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.

In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.

Joint pain relief

Most Useful Review

8 people found this helpful

I drank two capsules each morning with breakfast for three weeks. I've noticed increased endurance during cardio workouts and no knee pain, which was a previous issue during lunges and squats. This product has worked well for me and my husband, with no mouth or stomach discomfort experienced. I highly recommend it!

Acne details

Conforti C, Agozzino M, Emendato G, Fai A, Fichera F, et al. Acne and diet: a review. Int J Dermatol. 2022;61:930. doi:10.1111/ijd.15862

Based on 18 Researches

Omega-3 may improve acne

We observed that acne is a common skin condition, particularly affecting individuals under 30. Our exploration into the role of diet revealed that nutrition significantly influences acne development. Among the various dietary components, omega-3 fatty acids stood out due to their potential anti-inflammatory properties.

The research indicates that foods rich in omega-3 can help reduce the production of inflammatory substances that may contribute to acne. Additionally, specific fatty acids, such as docosapentaenoic acid and γ-linolenic acid, have shown promise in improving acne lesions.

By integrating omega-3 into the diet, we might be able to mitigate some of the troublesome symptoms associated with acne. While the evidence is still unfolding, the link between omega-3 fatty acids and reduced acne severity offers a hopeful avenue worth considering for those battling breakouts.

7.5

Skin quality improvement

Most Useful Review

3 people found this helpful

I first purchased fish oil for its cost-effectiveness and lemon flavour. I was pleasantly surprised by how comfortable I felt and noticed an improvement in my skin quality, which had been prone to acne due to my meat-heavy diet. The subtle lemon aroma made it easy to consume, and the packaging is appealing. It seems to be an essential supplement for me.

Autoimmune Disorder details

Resolvin D1 impacts lupus progression

Huang L, Wu J, Cao J, Sheng X, Wang M, et al. Resolvin D1 inhibits T follicular helper cell expansion in systemic lupus erythematosus. Scand J Rheumatol. 2024;53:276. doi:10.1080/03009742.2024.2344906

We focused on how Resolvin D1 (RvD1), a pro-resolving lipid, impacts systemic lupus erythematosus (SLE). Our study measured RvD1 levels and T follicular helper (Tfh) cell counts in SLE patients versus healthy individuals.

We found that higher RvD1 levels correlated with lower disease activity and fewer Tfh cells. RvD1 was effective in reducing Tfh cell activity in a mouse model and inhibited Tfh differentiation in lab tests.

Overall, RvD1 appears to play a significant role in managing SLE by suppressing Tfh cells and influencing immune responses.

Supports overall health

Most Useful Review

8 people found this helpful

I've consumed dietary supplements for 18 years and find Omega-3 beneficial for various health aspects, including memory and metabolism. Recommended by my therapist to lower cholesterol, I appreciate the quality here and take them with meals daily. This Omega-3 aids in maintaining good mood and skin, which is essential for treating my autoimmune disorder. It’s a family staple due to its effects and reasonable price.

Bloating details

Omega-3s help reduce PMS bloating

Sohrabi N, Kashanian M, Ghafoori SS, Malakouti SK. Evaluation of the effect of omega-3 fatty acids in the treatment of premenstrual syndrome: "a pilot trial". Complement Ther Med. 2013;21:141. doi:10.1016/j.ctim.2012.12.008

We observed the effectiveness of omega-3 fatty acids in treating symptoms of premenstrual syndrome (PMS) in a well-structured study with 184 women. Participants were divided into two groups, receiving either omega-3 supplements or a placebo over three months.

Encouragingly, we found that those taking omega-3 reported reduced bloating along with other symptoms like anxiety and headaches. Furthermore, these benefits increased with longer treatment durations. Overall, omega-3 fatty acids show promise for alleviating bloating in women suffering from PMS.

No bloating here

Most Useful Review

Excellent! A good omega-3 supplement that is easy to take and does not cause bloating. It is essential for managing cholesterol levels.

Cardiovascular Disease details

Omega-3 levels reduce heart failure

Based on 33 Researches

Jawad MA, O'Keefe JH, Tintle N, O'Keefe EL, Franco WG, et al. Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. Mayo Clin Proc. 2024;99:1895. doi:10.1016/j.mayocp.2024.08.007

We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.

For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.

Cardiovascular remedy

Most Useful Review

33 people found this helpful

This "Mega" omega fish oil is superb! It helps reduce cholesterol concentrations, acts as a preventive measure against cardiovascular disease, and has shown potential in cancer prevention. Omega 3 aids in skin conditions, allergies, and arthritis, often providing relief in just days. It's crucial for brain function and normal embryo development. I take 3-4 capsules daily with meals.

Constipation details

Fish oil is remarkable. Anyone suffering from constipation will quickly appreciate the benefits it offers.

Dizziness details

After years of reliance on medications for sleep, I found this product excellent. After six months, I recommend taking 5mg or 3mg for sleep; it works well and suits morning people. If you drink coffee, 10mg is suitable but may cause slight dizziness and sleepiness initially. That feeling fades after some time.

Blood Clot details

Fish oil reduces catheter-related clots

Based on 29 Researches

Jami MM, Bhardwaj V, Merritt RJ. Intravenous Fish Oil Lipid Emulsion Prevents Catheter-Related Thromboses in Pediatric Patients with Intestinal Failure. J Pediatr. 2018;198:301. doi:10.1016/j.jpeds.2018.03.029

We analyzed the effects of fish oil lipid emulsion on the prevention of deep vein thrombosis in children with intestinal failure.

In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.

Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.

Headache relief

Most Useful Review

4 people found this helpful

I have been taking Omega for four months now, and my body feels much better. My headaches and fluctuating blood pressure have disappeared. Previously, I used omega from two other brands, but this third one with a hint of lemon is my favourite. The jar is sturdy and lasts for about 75 days. I used to be sceptical about supplements, but this has genuinely improved my vascular health and eliminated the need for pressure medication since autumn. I am very pleased!

Diarrhea details

Takenouchi S, Imai D, Nakamura T, Murata T. Efficient Attenuation of Dextran Sulfate Sodium-Induced Colitis by Oral Administration of 5,6-Dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic Acid in Mice. Int J Mol Sci. 2021;22. doi:10.3390/ijms22179295

Based on 8 Researches

5,6-DiHETE alleviates diarrhea

We examined how eicosapentaenoic acid, specifically a compound called 5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid (5,6-DiHETE), affects diarrhea caused by inflammation in mice. In our study, the mice were given a substance that induces colitis, known as dextran sulfate sodium (DSS), and then treated with different doses of 5,6-DiHETE orally.

What we found was promising: the administration of both 150 and 600 micrograms of 5,6-DiHETE daily helped to speed up the recovery from diarrhea. After just a few days of treatment, we observed significant improvements in the mice’s condition. The daily doses led to less inflammation in the colon and a notable reduction in the symptoms of diarrhea associated with DSS-induced colitis.

We also measured how much of this compound remained in the mice's blood after taking it, finding that it peaked within half an hour of administration. This suggests that 5,6-DiHETE works relatively quickly to start affecting the inflammation. Overall, our research indicates that eicosapentaenoic acid holds potential as a beneficial treatment for inflammatory bowel diseases that cause diarrhea.

7.5

No bad breath

Most Useful Review

It tastes excellent, does not cause bad breath, and I’ve not experienced any diarrhoea.

Heart Attack details

Omega-3s' mixed effects on heart health

Based on 37 Researches

Rodriguez D, Lavie CJ, Elagizi A, Milani RV. Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health. Nutrients. 2022;14. doi:10.3390/nu14235146

We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.

Heart health support

Most Useful Review

1 people found this helpful

Value Pack Omega-3 Fish Oil helps support heart and brain health, and maintains healthy triglyceride levels. It's molecularly distilled to remove harmful substances. Some studies suggest omega-3 may reduce heart attack risk.

Heart Disease details

Omega-3 reduces heart disease risk

We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.

For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.

Cardiovascular benefits

Most Useful Review

33 people found this helpful

"Mega" omega!!! This quality fish oil contains essential omega-3 fatty acids, which significantly lower cholesterol levels and aid in preventing heart disease. Omega-3 has been noted by oncologists for slowing tumour growth and is effective for various skin ailments. It also reduces allergy symptoms in children, aids in wound healing, and helps with arthritis by promoting anti-inflammatory prostaglandins. Omega-3 is vital for brain function and can help pregnant women develop the embryo. I take it daily to regulate fat metabolism and support overall health.

High Cholesterol details

Omega-3 EPA+DHA improves cholesterol

Zhou Q, Zhang Z, Wang P, Zhang B, Chen C, et al. EPA+DHA, but not ALA, Improved Lipids and Inflammation Status in Hypercholesterolemic Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Mol Nutr Food Res. 2019;63:e1801157. doi:10.1002/mnfr.201801157

We conducted a comprehensive trial to understand how different types of omega-3 fatty acids affect cholesterol levels and inflammation in adults struggling with high cholesterol.

Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.

Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.

7.5

Good prevention

Most Useful Review

419 people found this helpful

This Omega-3 fish oil is excellent for health. It provides adequate doses of essential fatty acids and adheres to GMP standards. While it lacks the highest concentration of Omega-3s, it's cost-effective. I use it for skin and hair beauty, and my parents take it to maintain heart health. I recommend it, just follow the instructions of taking two capsules daily with meals.

Food Poisoning details

Liao J, Bi S, Fang Z, Deng Q, Chen Y, et al. Docosahexaenoic Acid Promotes Cd Excretion by Restoring the Abundance of in Cd-Exposed Mice. Molecules. 2023;28. doi:10.3390/molecules28104217

Likely Very Effective

DHA promotes cadmium excretion

We explored the effects of docosahexaenoic acid (DHA) on cadmium (Cd) exposure, a common pollutant that risks human health through the food chain. Our investigation focused on how DHA might help mitigate the harmful effects of Cd, particularly by looking at changes in gut microbiota.

The study involved examining mice that had been exposed to cadmium. We observed that DHA significantly boosted the amount of cadmium expelled in feces while reducing the levels of cadmium accumulated in various organs. Our findings highlighted a particularly encouraging increase in Parabacteroides, a beneficial bacteria in the gut that appeared to play a crucial role in this process.

We noted that the representative strain of Parabacteroides not only demonstrated the ability to reduce Cd toxicity but also helped repair gut damage inflicted by cadmium exposure. Furthermore, DHA effectively reduced cadmium levels in organs such as the liver, spleen, and kidneys, leading to a noticeable increase in cadmium excretion.

Overall, our results suggest that DHA may have significant potential in promoting the excretion of cadmium in instances of exposure. This insight offers a fascinating avenue for considering DHA as a supportive treatment option for handling heavy metal toxicity.

7.5

Enhanced concentration noted

Most Useful Review

1 people found this helpful

After two months of using this Omega-3, my mother has shown improved concentration and memory retention. The high DHA content is quite impressive for its price, making it worth the purchase. I researched Omega-3s extensively and found that DHA and EPA are essential for longevity and children's development. Their deficiency can lead to numerous health issues. Omega-3 sources include fish oils, zooplankton, and microalgae.

Rash details

Rhodes LE, White SI. Dietary fish oil as a photoprotective agent in hydroa vacciniforme. Br J Dermatol. 1998;138:173.

Based on 3 Researches

Promising results for fish oil

We investigated the impact of dietary fish oil, rich in omega-3 fatty acids, on hydroa vacciniforme, a challenging photosensitivity disorder. Three boys with the condition took five capsules of MaxEPA daily for three months. During follow-up tests, we observed that all boys had lower sensitivity to UVA light, indicating a positive response to the treatment.

While one child demonstrated a significant improvement, another showed mild progress, and the third did not improve but later responded well to another medication. Overall, fish oil may reduce UV sensitivity and improve rash outcomes for some patients.

Skin improvement

Most Useful Review

2 people found this helpful

The best. I am 27 years old. I started taking Omega 3 on the advice of a beautician alongside vitamin D3 due to skin and hair issues. After just one jar, the results are evident. My hair has stopped falling out, and my skin is hydrated; the rashes on my face have disappeared. I really like this Omega 3 as it contains natural lemon oil, which is good for the stomach. The dosage of Omega is 1000 mg, which is excellent. I've ordered it twice already, and while I've tried Omega 3 from another company, I will definitely reorder from this one.

Allergies details