Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Proprietary Probiotic BlendProviding 1 billion CFUBifidobacterium longum BB536, HOWARU® Lactobacillus acidophilus NCFM®
11 mg
**
The product is found useful for the following medical conditions
Yeast Infection details
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.7
9
We explored how Lactobacillus acidophilus ATCC 4356 impacts yeast infections caused by Candida albicans. The study used both in vitro and in vivo models, with tests on biofilm formation and filamentation in lab settings and survival analysis in Galleria mellonella larvae.
Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
10
Life-changing impact
Most Useful Review
22 people found this helpful
Buy this TODAY if you have a yeast infection. I discovered this product while desperately seeking a cure for recurrent yeast infections that my doctor attributes to hormonal changes. This product, along with acidophilus pills, has transformed my life. I had monthly yeast infections for six years, despite various treatments. Since using this product daily, I've been yeast-infection free for four months! This has also helped with bowel irregularities. Honestly, GET THIS TODAY; it's the best deal I've found!
Updated: Apr 2025
Bloating details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.4
USERS' SCORE
Good
Based on 16 Reviews
8.6
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
9
Bloating resolved
Most Useful Review
141 people found this helpful
GREAT! Wish I had tried these years ago! After suffering from various digestive issues, I decided to try Pearls, and the difference is remarkable. Within two days, bowel regularity improved, bloating was gone, and my nausea significantly decreased. I now take it once in the morning and once after dinner, reducing my reliance on acid blockers, which can worsen constipation. I highly recommend trying Pearls for anyone with similar issues; they are worth the investment.
Updated: Apr 2025
Ear Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
Yeast Infection Cure
Most Useful Review
22 people found this helpful
I found this product to be a lifesaver for my recurring yeast infections, which I experienced monthly for six years. Since starting on this product, I have not had any yeast infections in the last four months. It significantly improved my situation, and I highly recommend it for anyone struggling with similar issues.
Back Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Regular bowel movements
Most Useful Review
37 people found this helpful
For me, life-changing. Since my teen years, I've struggled with constipation. After being diagnosed with colitis, I found a prescription that controlled my issues, but it didn't last. Since taking these pearls daily for over two months, I am now regular and solid, without any tummy pains or back pain. These tiny pearls have made a significant difference to my life.
Colitis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Regular bowel movements
Most Useful Review
37 people found this helpful
For me, this has been life-changing. Since my teens, I struggled with constipation, then faced a diagnosis of a rare form of colitis that prevented me from holding it in. Working with my doctor, I found a prescription that helped but I frequently returned to being constipated. Since taking these supplements daily for over two months, I am now regular and haven’t experienced tummy pain. I've never gone two or three days without issues for the last 20 years, so for me, these small pearls are truly transformative.
Gastroesophageal Reflux Disease details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
10
Effective GERD management
Most Useful Review
5 people found this helpful
I have been using this product for the past two years and I wouldn't be without it. It has helped tremendously in managing my Gastroesophageal Reflux Disease, allowing me to avoid over-the-counter antacids or prescription medications.
Updated: Mar 2026
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.1
USERS' SCORE
Good
Based on 2 Reviews
8.4
8
Probiotics improve acne severity after twelve weeks
We analyzed nine randomized trials involving 623 acne patients to see whether probiotics could help reduce breakouts. Early results at four weeks were modest, but after twelve weeks, probiotics showed real promise. They significantly reduced disease severity, lowered the total number of lesions, and even improved skin hydration and oil content compared to placebo.
The good news? Probiotics were well-tolerated with no major side effects reported. While more research is needed, these findings suggest probiotics may offer a genuine therapeutic benefit for people struggling with acne.
The good news? Probiotics were well-tolerated with no major side effects reported. While more research is needed, these findings suggest probiotics may offer a genuine therapeutic benefit for people struggling with acne.
8
Essential after antibiotics
Most Useful Review
135 people found this helpful
These acidophilus pearls are easy to take and essential after a course of antibiotics. They help establish friendly bacteria in the bowel, which benefits anyone, particularly acne sufferers. Highly recommended to re-establish gut health!
Updated: Apr 2026
Bacterial Infection details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.4
8
Lactobacillus aids pigs' health
We explored the effects of Lactobacillus acidophilus fermentation products on weanling pigs that were challenged with a harmful strain of bacteria known as enterotoxigenic F4 Escherichia coli (F4-ETEC). To better understand this, we conducted a detailed study involving eighty pigs, which were divided into five groups based on different diets. This included a control diet, as well as diets supplemented with various fermentation products and zinc oxide.
After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.
Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.
After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.
Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.
9
Bacterial skin infection control
Most Useful Review
2 people found this helpful
If you own an English Bulldog, you need these! Our rescue bulldog had severe skin issues and was on antibiotics for a bacterial infection for six months. While the antibiotics worked, the symptoms returned soon after we stopped them. After some trial and error with the pearls, I saw improvement—his eyes and nose stopped running, and the staining cleared up remarkably. I’m now on my second box, and his appearance has improved dramatically, with no more staining or licking issues. These pearls seem to effectively address the bacteria causing the staining.
Updated: Apr 2025
Nausea details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 2 Reviews
8.4
8
We conducted a double-blind, placebo-controlled study to assess how Lactobacillus acidophilus might help with stress-related gastrointestinal issues, particularly nausea. Over three weeks, volunteers received either a probiotic called Probio-Stick or a placebo.
We found that consumption of the probiotics significantly eased nausea and abdominal pain linked to stress. However, it didn't have a notable impact on other symptoms like sleep problems or psychological distress. Overall, our findings suggest that Probio-Stick is effective for alleviating certain gastrointestinal symptoms caused by stress.
We found that consumption of the probiotics significantly eased nausea and abdominal pain linked to stress. However, it didn't have a notable impact on other symptoms like sleep problems or psychological distress. Overall, our findings suggest that Probio-Stick is effective for alleviating certain gastrointestinal symptoms caused by stress.
8
Effective for constipation
Most Useful Review
141 people found this helpful
What a difference these probiotics have made! After years of constipation and digestive issues, I hesitated to try probiotics for fear they might worsen my condition. After discovering "burns" in my stomach from acid, I decided to try Pearls. Merely two days in, I experienced significant improvements. My bathroom visits increased, the bloating and nausea disappeared, and acid reflux has vastly improved. Now, I rarely need antacids, a remarkable change from before. I urge anyone with similar issues to try Pearls.
Updated: Apr 2025
Constipation details
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.4
USERS' SCORE
Good
Based on 13 Reviews
8.3
7
We evaluated the impact of Bifidobacterium longum BB536 on chronic constipation in elderly individuals through a randomized, double-blind trial in Japan, involving 80 participants.
Although the primary outcomes showed no significant improvement, we did observe noteworthy enhancements in bowel movements among those taking the probiotics compared to the placebo group.
This suggests that while not a complete solution, B. longum BB536 may still provide safe and beneficial effects for older adults struggling with constipation.
Although the primary outcomes showed no significant improvement, we did observe noteworthy enhancements in bowel movements among those taking the probiotics compared to the placebo group.
This suggests that while not a complete solution, B. longum BB536 may still provide safe and beneficial effects for older adults struggling with constipation.
10
Constipation relief
Most Useful Review
141 people found this helpful
GREAT! I wish I had tried these years ago! After an endoscopy that revealed "burns" in my stomach, I decided to try Pearls. They have made such a difference! I suffered from constipation for 7 years following thyroid removal, and nothing seemed to help. Within just two days of starting Pearls, I began to have regular bathroom visits. The bloating and nausea disappeared, and while my reflux isn't completely gone, it's significantly improved. I recommend Pearls for anyone struggling with constipation.
Updated: Apr 2025
Reflux details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
7.5
Probiotics improved reflux
Most Useful Review
141 people found this helpful
I wish I had tried probiotics years ago. I had many digestive issues, including reflux and bloating. After trying Pearls following an endoscopy that showed acid burns, I experienced significant improvement within days. My nausea and bloating disappeared, and my reflux remains much better. I used to take Zantac frequently, but now I only take it occasionally, thanks to Pearls.
Updated: Apr 2025
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.9
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
Lactobacillus shows promise against flu
We explored the effects of heat-killed Lactobacillus gasseri TMC0356 on mice infected with the flu virus. After 19 days of treatment, we observed improved clinical symptoms, reduced viral loads, and enhanced immune responses in the treated mice compared to controls. This suggests that Lactobacillus could bolster both gut and respiratory immunity against influenza. However, these exciting results are limited to animal studies, and further research in humans is needed to fully understand its benefits.
9
Life-changing product
Most Useful Review
22 people found this helpful
Buy this TODAY if you have a yeast infection. I stumbled across this product one night while desperately seeking a 'cure' for yet another yeast infection caused by hormones. My doctor suggested trying different kinds of acidophilus, and this product, along with the pills, has genuinely changed my life. I went from struggling with a yeast infection EVERY MONTH for six years—despite various diets, Diflucan, and creams—to not having a single one in the past four months since taking this daily. Initially, I took higher doses but now follow the bottle's recommendation. Although the higher doses caused some discomfort, I eventually adjusted to a suitable regimen. If you face similar challenges, you must try this. It's the best value I've found!
Updated: Mar 2026
Heartburn details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.2
8
Positive effects on gastrointestinal symptoms
Our research aimed to understand how a specific symbiotic gel, containing Lactobacillus acidophilus, affects gastrointestinal symptoms, including heartburn, in hemodialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
10
Natural heartburn remedy
Most Useful Review
4 people found this helpful
Stopped daily heartburn—finally! I discovered that acidophilus could help chronic heartburn. Rather than continuing to use daily Pepcid tabs, which I took excessively, I tried these. Within a week, I no longer needed Pepcid at all! I plan to order these regularly, especially since they are cheaper than Pepcid. My digestion is also more regular.
Updated: Apr 2025
Diarrhea details
SCIENTIFIC SCORE
Moderately Effective
Based on 31 Researches
8.3
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
9.5
Probiotics improve H. pylori treatments
We analyzed various studies on incorporating probiotics into treatments for Helicobacter pylori (H. pylori) infection. Our findings revealed that adding probiotics like Bifidobacterium longum improved the eradication rate significantly.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
7.5
Effective probiotics
Most Useful Review
11 people found this helpful
I used to suffer from flu-like symptoms after working out, which seemed connected to my exercise routine. I'd tried everything to stop it. Eventually, I found out that many people had a similar experience and found relief with probiotics. After trying Enzymatic Therapy Acidophilus Pearls, I've noticed many of my digestive issues, including diarrhea, have almost disappeared. My energy levels have improved, and I no longer get sick post-exercise. Highly recommended!
Updated: Apr 2025
Data last updated:
