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Supplement Facts
Serving Size:   1 Tablet
Amount Per Serving
%DV
Zinc (as zinc glycinate amino acid chelate†)
22 mg
200%

The product is found useful for the following medical conditions

Acne

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Good
Based on 22 Reviews
8.8
8
Zinc effective for acne treatment
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.
Most Relevant Research
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.

Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.

Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
10
Long-term acne relief
Most Useful Review
Great for acne! After 20 years of suffering with acne, this is the first time I have gone weeks and now months without a single breakout. Initially, I still had some breakouts, but they gradually diminished. I am convinced this vitamin has stopped my daily bumps effectively. Zinc wasn't recommended by any dermatologist I visited, but after hearing Dr. Oz, I realised its importance for treating acne and could've avoided years of embarrassment.

Common Cold

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 41 Reviews
8.7
9
Zinc shortens cold duration variability
Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration.
Most Relevant Research
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.

Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.

Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.

Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
9.5
Cold prevention
Most Useful Review
My experience with chelated zinc has been very positive. I noticed improvements in my skin and a significant reduction in colds. Unlike traditional views emphasising vitamin C, zinc is now recognised for its effectiveness in combating the common cold and even reducing complications. The tablets are small and easy to swallow, with no side effects.

Chronic Cough

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Prevention effectiveness
Most Useful Review
This is the best zinc on iHerb! It's challenging to find. If it appears, don't hesitate. Firstly, it's from Solgar, a trusted brand. Secondly, it's a chelated form, making it better absorbed. My family and I take it regularly. When I contracted Covid, I had no fever, cough, or sore throat. Though I was fatigued for five days, I recovered quickly. I believe the zinc, alongside vitamin D, helped tremendously. Those with my weight often face complications, so please prioritise prevention.

Pelvic Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Reduced pelvic pain
Most Useful Review
I had suffered from prostatitis for years. After taking this zinc supplement, I noticed the pelvic pain significantly reduced. It seemed to improve my erectile function as well. I discovered a chelating zinc that is cheaper and more effective than domestic options. Now, I feel completely relieved, which is remarkable. I strongly recommend this to others suffering from prostatitis; it truly makes a difference.

Urinary Tract Infection

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.7
USERS' SCORE
Good
Based on 1 Review
8.6
8
Zinc-Infused Catheters Reduce Infections
Antimicrobial and Antibiofilm Activities of Urinary Catheter Incorporated with ZnO-Carbon Nanotube.
Most Relevant Research
We investigated the potential of a new type of urinary catheter to tackle catheter-associated urinary tract infections (CAUTIs). By incorporating zinc oxide-carbon nanotubes (ZnO-CNT) into a silicone catheter, we explored how this innovative design could inhibit infection-causing bacteria effectively.

Utilizing a combination of laboratory techniques like scanning electron microscopy and dynamic light scattering, we analyzed the structure of our ZnO-CNT catheter, which showed promising antibacterial properties. Notably, we found that the ZnO-CNT infusion significantly reduced biofilm formation—one of the main challenges in urinary catheters—demonstrating up to 56% inhibition in bacterial growth compared to standard silicone catheters.

The study revealed that ZnO-CNT not only holds antimicrobial potential but may also provide a more comfortable alternative to existing metal-coated options, like those using silver or gold. With our findings, we hope to present a viable strategy for reducing the discomfort and risks associated with traditional catheters while addressing a prevalent healthcare concern.
9.5
Strengthens immunity
Most Useful Review
An excellent remedy for enhancing immunity, particularly against coronavirus infections. The tablets are small and easy to swallow, which I prefer as I dislike larger pills.

Warts

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5.5
USERS' SCORE
Good
Based on 1 Review
8.6
7
Nitric-zinc solution shows effectiveness
Treatment of Plantar Warts with a Nitric-Zinc Complex Solution: A Review of 72 Cases.
Most Relevant Research
We explored a new treatment approach for plantar warts using a nitric-zinc complex solution. In this study involving 72 patients, we aimed to observe how effective this solution is in achieving complete healing of warts.

The results were promising, showing a 59.2% cure rate after treatments. On average, patients received about 5.9 applications of the solution over a duration of around 9.4 weeks. Additionally, the recurrence rate was relatively low, noted at 6.7%.

Although we can’t isolate the specific contributions of zinc alone since it was part of a combined treatment with nitric acid, these findings suggest that the nitric-zinc complex could serve as a viable option for those suffering from plantar warts. This treatment may be considered among the first-line options for managing this common skin condition.
9.5
Increased fertility
Most Useful Review
Baby making pills. It seems to have resolved these cursed plantar warts on my feet while unexpectedly increasing my fertility, leading to significant changes for me in the coming months.

Gout

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
8
Zinc nanoparticle aids gout treatment
A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway.
Most Relevant Research
We investigated how zinc, specifically in the form of zinc ferrite nanoparticles (ZFN), can impact gouty arthritis. The research focused on finding a safe and effective treatment option to help people dealing with this painful condition, which often affects various age groups.

To explore this, we created ZFN, which has notable activities that help combat inflammation and oxidative stress, while also being gentle on the body. What’s interesting about ZFN is that its low zinc content helps avoid some of the common issues with other zinc-based treatments, such as toxicity. We tested ZFN through both laboratory studies and real-life models to see its effectiveness fully.

Our results were promising! We observed that ZFN significantly reduced inflammation and oxidative stress associated with gout. It seems to work by influencing important body pathways, particularly weakening signals that promote inflammation while boosting the body's natural defenses. This modulation signifies a powerful method for treating gout without the heavy side effects of current medications.

The discoveries we made in this study not only highlight a new potential treatment for gouty arthritis but also demonstrate the wider applicability of nanotechnology in health. The protective benefits of ZFN pave the way for more developments in treating inflammatory conditions like gout.
8.8
Reduced gout attacks
Most Useful Review
One of the self-organised anti-gout formulas has indeed proved effective in lessening the frequency of gout attacks. I must admit it has significantly aided the relationship between my husband and me.

Pneumonia

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Reduced hair loss
Most Useful Review
I was ill with pneumonia, and during my treatment, I noticed increased hair loss. After the first week of taking zinc, I observed that my hair fell out less, and my nails no longer exfoliate.

Hair Loss

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
USERS' SCORE
Good
Based on 1 Review
8.5
9
Zinc shows promise for hair loss
Symptom Profile of Patients With Post-COVID-19 Conditions and Influencing Factors for Recovery.
Most Relevant Research
We explored how zinc acetate hydrate impacts hair loss for patients experiencing symptoms after COVID-19. In our analysis, we looked at 120 symptomatic outpatients over 12 weeks, observing their recovery patterns and any improvements in their symptoms. The focus was on various lingering effects, including fatigue and hair loss, particularly how zinc could potentially alleviate these issues.

Our findings highlighted significant improvements in hair loss for those treated with zinc acetate hydrate at multiple checkpoints (4, 8, and 12 weeks) compared to those who did not receive this treatment. The results were statistically significant and suggested that zinc could be a useful option for those struggling with hair loss post-COVID-19.

Additionally, we noted improvements in fatigue among those receiving zinc, although this was not as pronounced at all time intervals. As a whole, our study emphasized zinc's beneficial effects, particularly for hair loss, providing promising insights for anyone dealing with these challenging post-viral symptoms.
8.8
Promotes hair growth
Most Useful Review
This product works, but patience is key. It aids in hair growth and combats hair thinning due to stress. Pair it with copper vitamins for added effect. Expect about 5-6 months to observe 2 inches of new growth. Persistence paid off for me, and I have proof!

Liver Disease

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.1
USERS' SCORE
Good
Based on 1 Review
8.4
9
Zinc's Role in Liver Health
Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings.
Most Relevant Research
We focused on the connection between zinc and liver health, particularly how it may influence conditions like non-alcoholic fatty liver disease (NAFLD) and metabolic issues, including type II diabetes (T2D). Our analysis of data from a large genetics cohort revealed a significant finding: rare genetic variants that reduce the function of the zinc transporter SLC39A5 were linked to better metabolic profiles and lower T2D risk.

To delve deeper into these results, we used both laboratory and animal models. We developed mice that completely lacked SLC39A5 and observed promising outcomes. These mice showcased improved liver function and lower blood sugar levels after being subjected to obesity challenges, whether congenital or diet-induced.

Notably, this improvement seemed to be associated with increased levels of zinc in the liver, which activated key signaling pathways involved in metabolism, such as AMPK and AKT. Furthermore, these mice exhibited less liver inflammation and fibrosis in models of diet-induced non-alcoholic steatohepatitis (NASH).

Together, these findings position SLC39A5 as a potentially valuable target for treating liver-related metabolic disorders, emphasizing zinc's crucial role in managing liver health and blood sugar regulation.
7.8
Supports liver health
Most Useful Review
Chelated Zinc, 250 tablets by Solgar, offers an easily absorbed form of zinc, crucial for the body's organ functions. This product aids the liver's work and helps regulate the nervous and endocrine systems, promoting overall health and potentially assisting in the management of liver disease.

Tinnitus

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 3 Reviews
8.4
7
Zinc intake affects tinnitus risk
The Association between Dietary Intakes of Vitamins and Minerals with Tinnitus.
Most Relevant Research
We examined how dietary intakes of vitamins and minerals, particularly zinc, could influence the onset and presence of tinnitus, a condition characterized by phantom sounds in the ears. In a study involving nearly 3,000 participants over the age of 50, we identified cases of tinnitus to determine if their dietary habits played a role in their experience of this condition.

The findings indicated that while there were no significant associations between overall vitamin and mineral intake and existing tinnitus prevalence, zinc intake stood out in relation to developing tinnitus over time. Specifically, we observed that lower zinc consumption was linked to a 44% increased risk of experiencing tinnitus over a ten-year period.

Furthermore, we noted that iron intake also showed a significant correlation, with lower iron levels raising incident tinnitus risk by approximately 35%. These results highlight the potential importance of maintaining adequate zinc and iron levels in our diets to help reduce the risk of developing tinnitus.
9.5
Pain relief
Most Useful Review
Amazing! It helps me cope with various pains and provides relief for nearly non-existent tinnitus. A lifesaver!

Nausea

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.5
USERS' SCORE
Good
Based on 20 Reviews
8.3
7
Zinc treatment reduces nausea risk
Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia.
Most Relevant Research
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.

For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.

Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
9.5
No nausea
Most Useful Review
Very good and affordable! I've been using it for a year and find it beneficial to my health. It’s easy to take, and I have experienced no nausea when consumed after meals.

Cold Sores

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.2
9
Zinc cream alleviates cold sores
A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine.
Most Relevant Research
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.

Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.

As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
9
Improved male health
Most Useful Review
Helped me with a cold, and my boyfriend is thrilled with the result – these are excellent male vitamins. This Zinc delivers a good effect and helped him overcome a cold in two days. He noticed a significant difference after just five days, stating that men should monitor their zinc levels. However, we did notice some tingling in his side after taking it for five consecutive days, which we are monitoring. Overall, these vitamins are highly commendable.

Blood Clot

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Moderately Good
Based on 1 Review
7.9
8
Zinc enhances blood clot formation
Enhanced coagulation cascade activation and styptic effects of Zn@SiO nanocomposite.
Most Relevant Research
We explored how zinc affects blood clotting, particularly through a substance called Zn@SiO nanocomposite. This material shows promise as a hemostatic agent, which means it helps stop bleeding by promoting the formation of stable blood clots.

During our analysis, we examined various aspects of how this nanocomposite interacts with blood. It activates specific factors in the coagulation cascade—the process our bodies use to form clots. With the presence of zinc in the material, we observed enhanced activation of these factors, leading to improved clot formation.

Our research involved synthesizing and characterizing the Zn@SiO nanocomposite using several methods, including XRD, FTIR, and HRTEM. We also tested its effects on red blood cell aggregation, platelet adhesion, and several vital clotting time measures. The results indicate that Zn@SiO has significant hemostatic properties, showing potential for use in surgeries and trauma care.

This study highlights the exciting role of zinc in optimizing hemostasis, making it a candidate worth considering for medical applications related to bleeding management.
2.3
No change observed
Most Useful Review
I did not find this product suitable. I ordered it for my child, who took one tablet for a month, but the zinc levels in their blood did not improve. It's quite disappointing. I will look for another zinc supplement.

Autoimmune Disorder

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.5
USERS' SCORE
Medium or Average
Based on 8 Reviews
6.9
9
Zinc supplementation benefits MS models
Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.
Most Relevant Research
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.

After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.

Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
9.5
Normalisation after COVID
Most Useful Review
After experiencing severe post-COVID fatigue, my doctor suggested zinc and vitamin D. I ordered it online and took it daily with my husband, and gradually my strength returned. The convenient dosage of one tablet daily worked well for us.
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