Solgar Vitamin C

Lee GW, Yang HS, Yeom JS, Ahn MW. The Efficacy of Vitamin C on Postoperative Outcomes after Posterior Lumbar Interbody Fusion: A Randomized, Placebo-Controlled Trial. Clin Orthop Surg. 2017;9:317. doi:10.4055/cios.2017.9.3.317

Based on 4 Researches

Vitamin C's limited impact on pain

We conducted a year-long study to investigate the effects of vitamin C on postoperative pain and recovery after a specific type of spine surgery known as posterior lumbar interbody fusion (PLIF). In this randomized, placebo-controlled trial, we worked with 123 patients, dividing them into two groups: one receiving vitamin C and the other a placebo.

Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.

So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.

Eased gastrointestinal pain

Most Useful Review

These vitamins are excellent throughout the year, especially during epidemics. They are perfect for sensitive stomachs, and I have not suffered from heartburn or gastrointestinal pain after taking them. When I feel unwell, I take two 500 mg tablets, and the next morning, I feel much better. I'm on my second can and will continue to use them!

Chronic Cough details

22 people found this helpful

I was initially sceptical, but after catching a cold, I remembered I had some ant tree bark. I followed the recommended dosage, along with vitamin C and D3, and within three days, my chronic cough was gone, and I felt healthy again. Last year, I had a severe cold that lasted a week, but this time I recovered swiftly. This product definitely made a significant difference in my recovery.

High Cholesterol details

Vitamin C reduces cholesterol levels

Based on 6 Researches

Tavakolinasab F, Hashemi M. Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis. J Anim Physiol Anim Nutr (Berl). 2025. doi:10.1111/jpn.14091

We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.

Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.

Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.

Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.

Prevention of disease

Most Useful Review

17 people found this helpful

I discovered iHerb through M. Rath's book "Cellular Nutrition" and I appreciate the wide selection of vitamins. I've found Vitamin C-Ester-C to be beneficial for protecting against ulcers caused by high acidity without harming the digestive tract. As humans do not produce Vitamin C, supplementation is essential, particularly for maintaining the integrity of blood vessel walls and preventing complications related to high cholesterol.

Indigestion details

Strengthened immunity

13 people found this helpful

I find this one of the safest types of vitamin C, especially for those like me who suffer from indigestion. Unlike ascorbic acid, the ester form doesn’t irritate my stomach’s mucosa because of its neutral pH. I've been taking it daily for 2.5 months, and I noticed a positive impact almost immediately. My immunity has improved significantly, and I haven’t experienced any gastrointestinal issues despite having high stomach acidity. Furthermore, this vitamin C helps with cold symptoms when taken at the onset. However, I experienced discomfort in my leg veins, which led me to stop taking it. The next day, I felt much better.

Blood Clot details

Kwon JH, Kim D, Cho H, Shin BS. Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b. J Int Med Res. 2019;47:1856. doi:10.1177/0300060518817408

Based on 6 Researches

Vitamin C enhances blood clotting

We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.

We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.

Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.

This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.

Aids blood clot

Most Useful Review

I've found that vitamin C with bioflavonoids is absorbed 35% better than regular ascorbic acid and is gentler on the stomach. It aids in thinning the blood, preventing blood clots and reducing heart strain. This improvement helps with varicose veins and overall blood circulation. If my review was helpful, please give it a thumbs up.

We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.

Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.

After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.

Reduced knee pain

Most Useful Review

1 people found this helpful

I've been taking Ester-S Plus Vitamin C each morning after breakfast for three months. I really like it; it has alleviated my fatigue, and my joints no longer hurt, especially my knee pain. I never thought I could improve my health this way. I used to get colds frequently, but after taking 500 mg twice a day, my cold symptoms subsided quickly.

Ulcer details

Gunton JE, Girgis CM, Lau T, Vicaretti M, Begg L, et al. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial. Br J Nutr. 2021;126:1451. doi:10.1017/S0007114520003815

Based on 10 Researches

Vitamin C enhances ulcer healing

We conducted a double-blind trial involving sixteen individuals with chronic foot ulcers to see how vitamin C impacts their healing. Half of the participants received 500 mg of vitamin C, while the others got a placebo.

After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.

Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.

Does not corrode stomach

Most Useful Review

85 people found this helpful

Super Vitamin C in ester form. It doesn’t corrode the stomach and can be taken by those suffering from an ulcer. We definitely use it in the fall.

Bruise details

Vitamin C improves bruising symptoms

Based on 9 Researches

Amisha F, Ghanta SN, Kumar A, Fugere T, Malik P, et al. Scurvy in the Modern World: Extinct or Not?. Cureus. 2022;14:e22622. doi:10.7759/cureus.22622

We explored how vitamin C can impact bruising, particularly in individuals experiencing a deficiency. The research highlighted a case involving an elderly woman who faced challenges such as weakness, easy bruising, and fatigue due to a lack of this vital nutrient.

After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.

This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.

Strengthens vessels

Most Useful Review

This supplement successfully strengthens my weak blood vessels. I take 500 ml every morning, resulting in healthier gums and the absence of small bruises.

Celiac details

8 people found this helpful

The Solgar company is one I approve of, as their products are halal, free from dairy, gluten, and wheat, and non-GMO. I've noticed an improvement in my immunity, hair, nails, and skin since using their supplements. The quality is excellent, and I strongly recommend it. I take one pill daily before breakfast, alongside collagen, on an empty stomach. As the capsules have no taste, they are easy to swallow. You will notice a difference after consulting your doctor, God willing.

Common Cold details

Hemilä H, Chalker E. Vitamin C reduces the severity of common colds: a meta-analysis. BMC Public Health. 2023;23:2468. doi:10.1186/s12889-023-17229-8

Based on 7 Researches

Vitamin C reduces cold severity

We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.

Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.

This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.

Strengthened immunity

Most Useful Review

780 people found this helpful

This is what I constantly take, and during a common cold, I increase the dosage by 2-3 capsules per day. It really helps, and I notice results almost immediately. My immune system feels more robust.

Herpes details

Prevents cold symptoms

This is the best vitamin C I’ve tried on iHerb. It’s the most effective one! Taking it 3-4 times a day during illness speeds recovery. At the first signs of a cold (and even with herpes), symptoms don’t escalate, and herpes subsides after itching without developing rashes.

Leg Cramps details

Leg cramps treatment comparison

Hammar M, Berg G, Solheim F, Larsson L. Calcium and magnesium status in pregnant women. A comparison between treatment with calcium and vitamin C in pregnant women with leg cramps. Int J Vitam Nutr Res. 1987;57:179.

We explored the effects of vitamin C on leg cramps in a group of 60 pregnant women through a double-blind trial. Participants received either calcium or vitamin C (1 g twice daily) as treatment. Our observations revealed that there was no significant difference in clinical improvement between the two treatment groups.

Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.

Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.

Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.

Invigoration noticed

Most Useful Review

1 people found this helpful

Reacta C has truly invigorated me and alleviated my leg fatigue.

Pneumonia details

I was ill with coronavirus pneumonia for about 30 days at home. I took this medication initially in large doses and noticed an immediate improvement in my symptoms, including less pain in my head and chest. I even felt more energetic and hopeful, which helped me avoid depression. I recommend it to others without vitamin C allergies.

Acne Rosacea details

Effective against redness

1 people found this helpful

Fabulous! There is little I can say to praise this vitamin C. It does not induce heartburn, which I often experience with other vitamin C products, making it particularly effective in combating acne rosacea. During the autumn-winter period, I noticed fewer capillary bursts and less facial redness. In short, I highly recommend it. However, it's best to consult a doctor regarding the dosage.

Anemia details

Haile A, Mara S, Belete Y, Dejene T. The Forgotten Disease in the 21st Century: Scurvy Outbreak in Hawassa Central Prison, Hawassa, Sidama, Southern Ethiopia, 2023. Int Med Case Rep J. 2023;16:847. doi:10.2147/IMCRJ.S438833

Based on 8 Researches

Vitamin C aids anemia treatment

We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.

Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.

Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.

Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.

Improves absorption

Most Useful Review

2 people found this helpful

Excellent vitamin C! I've been dealing with anaemia, so the doctor recommended an iron supplement. I purchased both iron and vitamin C to enhance iron absorption. This Ester-C form is easily tolerated, even on an empty stomach. Very satisfied with the results!

Bacterial Infection details

Prevented throat infection

Very good Vitamin C. When I had a sore throat with a cold, it helped immensely. I took it alongside echinacea, and it prevented the infection from descending into my lungs. I continue to take it for immune support, and the whole family does too! I highly recommend it!

Cold details

Effectiveness of Vitamin C on Colds

Based on 2 Researches

Hemilä H, Chalker E. Vitamin C for the common cold and pneumonia. Pol Arch Intern Med. 2025;135. doi:10.20452/pamw.16926

We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.

But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.

Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.

Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.

Immune support

Most Useful Review

780 people found this helpful

This is what I drink constantly, and during a cold, I increase the dosage to 2-3 capsules per day. It helps a lot and the results are almost immediate. My immune system feels strengthened.

Diarrhea details

Vitamin C improves diarrheic calf health

Based on 2 Researches

Zakariya MR, Ghasemi E, Hashemzadeh F, Ghorbani GR, Ahmadi F. Does vitamin C supplementation in milk improve growth and health of diarrheic calves?. Prev Vet Med. 2024;224:106122. doi:10.1016/j.prevetmed.2024.106122

We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.

Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.

The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.

Easily tolerated

Most Useful Review

This vitamin C is excellent as it is easily tolerated and does not cause diarrhoea. Together with bioflavonoids, it enhances absorption, and I've been taking it daily without any problems.

Gastritis details

Sasazuki S, Hayashi T, Nakachi K, Sasaki S, Tsubono Y, et al. Protective effect of vitamin C on oxidative stress: a randomized controlled trial. Int J Vitam Nutr Res. 2008;78:121. doi:10.1024/0300-9831.78.3.121

Based on 12 Researches

Vitamin C lessens oxidative stress

We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.

After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.

Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.

Effective for gastritis

Most Useful Review

82 people found this helpful

Vitamin C from Solgar has been a revelation for my chronic gastritis. Unlike other forms, this one doesn't cause stomach pain after a while. I've noticed increased energy and improved immunity. Even during a family illness, symptoms were mild. I take it alongside other vitamins as recommended by my gastroenterologist. Plus, I appreciate that I can pour the capsules into a drink without affecting digestion. Always consult your doctor and listen to your body. Stay healthy!

Heart Disease details

Vitamin C's uncertain heart benefits

Based on 8 Researches

Manolis AA, Manolis T, Melita H, Manolis AS. Role of Vitamins in Cardiovascular Health: Know Your Facts - Part 1. Curr Vasc Pharmacol. 2023;21:378. doi:10.2174/1570161121666230912155548

We aimed to understand the role of vitamin C in heart disease and its potential cardioprotective effects. Vitamin C is renowned for its antioxidant properties, which means it fights off harmful substances in our body, potentially reducing the risk of heart issues.

Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.

So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.

Quick recovery

Most Useful Review

4 people found this helpful

I used high doses of vitamin C for a cold while on holiday in Cyprus. After falling ill with a 38-degree temperature and sore throat, I followed a colleague's advice to take 1.5-2 grams of vitamin C in the early days. The recovery was swift; I felt almost normal the next day. Now, with autumn here, my family takes vitamin C, and we all remain well.

Sore Throat details

4 people found this helpful

I experienced cold symptoms during a summer trip and found vitamin C to be a tremendous aid. Upon feeling ill with a sore throat and fever, I took a large dose of vitamin C. Within a day, I nearly returned to normal. Now, I rely on Ester-C Plus, which is gentle on the stomach, and once again, it provides quick results for my family during colder months.

Swollen Lymph Nodes details

An excellent vitamin! My son fell ill, took two capsules daily and recovered within four days; previously, he relied on antibiotics. I also administered vitamin D and magnesium. He is 7 years old, had swollen lymph nodes and a sore throat, but just one capsule daily sufficed, and by the next day, the symptoms vanished. For prevention, I continued for an additional four days.

Cough details

1 people found this helpful

We drank a full course of vitamin C with the children over the month, and no one got sick this winter! We completely forgot about colds, coughs, and tonsillitis. Now every autumn, these capsules are a must, and I highly recommend them!

Flu details

Cai Y, Li YF, Tang LP, Tsoi B, Chen M, et al. A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice. Biomed Res Int. 2015;2015:675149. doi:10.1155/2015/675149

Based on 5 Researches

Vitamin C mitigates flu pneumonia

We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.

However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.

Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.

Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.

7.5

Prevented flu effectively

Most Useful Review

25 people found this helpful

Helps my immune system. I use this product to boost my immune health with natural ingredients. It helps keep bladder infections at bay. I take it to avoid getting the flu. Typically, I suffer from a severe flu every winter, but this year I did not get the flu. I usually buy this locally, but I appreciate the convenience of delivery. We could all benefit from stronger immune systems.

Adenoiditis details

Highly effective remedy

2 people found this helpful

My find for colds! An excellent tool for prevention and treatment. I've been taking it for 2.5 months without getting sick. At the first symptoms—sore throat or headache—I take it every three hours, and the symptoms vanish! I recommend it wholeheartedly.

Allergies details

Pleuran and Vitamin C aid asthma

Jesenak M, Hrubisko M, Chudek J, Bystron J, Rennerova Z, et al. Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma. Sci Rep. 2025;15:7146. doi:10.1038/s41598-025-91830-2

We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.

The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.

While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.

No allergies

Most Useful Review

9 people found this helpful

Wonderful! I am not allergic to it! My body did not tolerate other vitamin C brands; they always caused a red, itchy rash. This vitamin C didn’t cause any allergies, and I’m very pleased. I recommend it to anyone with similar issues; it may work for you.

Autoimmune Disorder details

Vitamin C impacts autoimmune response

Based on 11 Researches

Yin Y, Wu S. Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies. Cell Commun Signal. 2024;22:373. doi:10.1186/s12964-024-01756-x

We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.

Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.

Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.

Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.

Improved absorption

Most Useful Review

82 people found this helpful

Vitamin C is well assimilated and suitable for those with gastritis. I have chronic gastroduodenitis, and I've struggled with various forms of vitamin C causing stomach pain. After trying the Ester-formula from Solgar, I noticed that my stomach didn't hurt. I feel more energetic, and during a recent family illness, my symptoms were minimal. I combine this with vitamins A, E, and selenium, plus iron for better absorption. These capsules can even be added to a collagen drink, which aids digestibility.

Cold Sores details

Hovi T, Hirvimies A, Stenvik M, Vuola E, Pippuri R. Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution. Antiviral Res. 1995;27:263.

Based on 3 Researches

Vitamin C alleviates cold sores

We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.

Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.

Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.

In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.

Immunity boost

Most Useful Review

3 people found this helpful

An excellent tool for boosting immunity! I took two capsules each morning and evening, which did wonders for my cold symptoms.

Nausea details

Vitamin C ineffective against nausea

Very Likely Ineffective

Foessleitner P, Rager L, Mikula F, Hager M, Granser S, et al. The Role of hCG and Histamine in Emesis Gravidarum and Use of a Chewing Gum Containing Vitamin C as a Treatment Option: A Double-Blinded, Randomized, Controlled Trial. J Clin Med. 2024;13. doi:10.3390/jcm13175099

We explored the effects of vitamin C as a treatment for nausea and vomiting in pregnancy, also known as emesis gravidarum. Our study involved 111 participants, who were given either vitamin C-containing chewing gum, a placebo, or no treatment at all. We monitored them over two follow-up visits in early pregnancy to assess their symptoms.

While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.

Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.

Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.

Supports immunity well

Most Useful Review

3 people found this helpful

A wonderful product that promotes activity and boosts immunity. Despite having a sensitive stomach, I experienced no acidity or nausea while taking this vitamin.

Chest Pain details

Vitamin C improves coronary response

Based on 13 Researches

Schindler TH, Magosaki N, Jeserich M, Olschewski M, Nitzsche E, et al. Effect of ascorbic acid on endothelial dysfunction of epicardial coronary arteries in chronic smokers assessed by cold pressor testing. Cardiology. 2000;94:239.

We explored the effects of vitamin C on chest pain in chronic smokers experiencing endothelial dysfunction. In our study, 31 patients, who were undergoing diagnostic catheterization without significant coronary artery issues, participated in a controlled trial. They were given either an IV infusion of 3 grams of ascorbic acid (vitamin C) or a placebo saline solution before undergoing a cold pressor test to assess their coronary artery response.

The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.

This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.

7.5

Chest pain alleviated

Most Useful Review

64 people found this helpful

Solgar Ester-C Plus is a staple for me. It doesn’t irritate my stomach, even when taken on an empty stomach, which is crucial as I have gastritis. This product has proven effective for dealing with colds; it alleviates symptoms, including chest pain, and can even lower my temperature. I appreciate the 500 mg dosage, and I take 1000 mg during illness. I've never encountered an overdose or allergy. I highly recommend this quality product from Solgar.

Adrenal Gland Disorder details

Helps adrenal function

Excellent! I’ve been using these vitamins for three years, and they've significantly helped with my adrenal gland disorder. During cold season, my husband and I use them, which aids in recovering from ARVI more quickly.

Rash details

9 people found this helpful

Wonderful! I am not allergic to it! My body did not respond poorly to vitamin C from various manufacturers, as I usually develop a red rash on my elbow that itches. This particular vitamin C did not cause any allergies, which has made me very happy. I recommend it to anyone with similar issues; it may suit you too.

Chronic Fatigue Syndrome details

Kodama M, Kodama T. The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex. Int J Mol Med. 2005;15:109.

Based on 5 Researches

Vitamin C aids immune function

We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.

We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.

While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.

Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.

Increased energy

Most Useful Review

5 people found this helpful

Fantastic vitamin! Other brands caused stomach issues until I discovered Ester-C Plus, for which I’m very grateful. No stomach pain now, and I wake up energetic, with fatigue gone. This product is effective for my chronic fatigue syndrome. Highly recommend!

Headache details

Zhao D, Long X, Wang J. Association between dietary vitamin C intake and migraine in adults: A cross-sectional study of the National Health and Nutrition Examination Survey. J Hum Nutr Diet. 2024;37:1454. doi:10.1111/jhn.13366

Based on 2 Researches

Vitamin C intake reduces migraines

We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.

Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.

We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.

Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.

Eliminates headaches quickly

Most Useful Review

6 people found this helpful

This super vitamin allows me to remain well through winter. If I feel itching or discomfort, I take a double dose and the ailment vanishes. I've noticed that my headaches dissipate after taking it. It's a product I intend to use indefinitely!

Kidney Stones details