NOW Supplements L-Lysine

A friend followed the treatment plan prescribed by the doctor for improving vision, and she noticed a positive result for both herself and her child; their vision improved.

Candidiasis details

Strong result achieved

2 people found this helpful

I liked it very much! The result is very good. My thrush is chronic. I take it with black walnut and Darka. A strong and good result was achieved within four months.

Cough details

Cough relief achieved

Our cat, Kitty, nearly had her cough resolved after consuming this. I take it regularly.

Now's lysine is exceptional for regulating neuropathy caused by diabetes. The tablets are of a good size, supporting muscle maintenance through protein formation and benefiting overall health.

Diabetes details

I’ve struggled with herpes for ages, but this L-Lysine amino acid has halted my recurrent attacks. Just one pill daily significantly helps me, and it also benefits my immunity.

Heart Attack details

Heart Disease details

It effectively boosts immunity, collagen, and heart health. I mix it with L-Arginine to promote relaxation and overall well-being.

Hypothyroidism details

Improved sleep quality

3 people found this helpful

I prefer the 500 mg presentation as it is easier to swallow than the 1000 mg tablet. The quality is just as good, providing the same effect; I sleep peacefully and wake up refreshed. I follow Dr Ludwing Johnson's instructions for my hypothyroidism. My mother, who also suffers from fibromyalgia, now sleeps well without waking frequently. We've completed one 1000 mg bottle and have been using this 500 mg bottle for a month. Delivery to Escobedo, Nuevo León, Mexico, took 11 days.

Updated: Mar 2025

Insomnia details

Effective for insomnia

Excellent L-lysine 500 mg, 250 tablets. After 40 years of experience, I found that taking Lysine at a rate of 23-30 mg per kg of body weight has been beneficial for my insomnia, anxiety, and mood swings. The supply lasts about 2.5 months. I began with one capsule daily for a week, then increased to two, and finally three doses daily. This has resulted in a stabilised emotional state, reduced irritability, less hair loss, and improved sleep quality. I no longer wake up feeling broken, which is a significant improvement. I am pleased that this product is effective, not a placebo as is often the case.

5 people found this helpful

Irritable Bowel Syndrome details

An excellent drug! I suffered with tingling in my heart for a month. After using the medication, all symptoms disappeared literally in five days. I took three capsules a day, 30 minutes before meals, and the symptoms vanished completely. I feel energised! I am continuing the course but now only two capsules a day. Highly recommended!

Menopause details

Mood stabilization noted

Although I prefer not to take tablets, I must say this one has excellent absorption. It effectively manages and stabilises my mood, making it particularly beneficial for situations related to menopause.

For herpes and joint issues, this is excellent! It assisted with herpes where nothing else worked. After taking lysine, my shoulder joint pain, persisting for over a year, has vanished. I can now move my arm freely.

Pelvic Pain details

Effectively reduced symptoms

Swollen Lymph Nodes details

3 people found this helpful

Herpes appeared, but I recovered relatively easily. I purchased 500mg lysine as I frequently get cold sores. I took it once or twice a day, and after tiring myself, I had a terrible outbreak. I think I wasn't taking enough; I read that one needs about 30 mg per kg of body weight, which means 1500 to 2000 mg a day. After starting high doses of 1500-2000mg at the first signs of herpes, I noticed minimal tingling and swelling. I believe lysine is a strong ally for swollen lymph nodes and herpes!

Effective against illness

Whooping Cough details

This essential amino acid is brilliant. I used it in tandem with monolaurin during my week of illness (suffering from a violent barking cough), drinking plenty of water. It helped me considerably, and I ordered more. My husband received one capsule of l-lysine and monolaurin at the onset of his symptoms, and he felt much better after a couple of days.

Allergy improvement noted

Allergies details

Improves allergy and immunity.

Chronic Cough details

Prevented chronic cough

I tested L-lysine while visiting a friend whose family had an infectious cold. I took two tablets daily alongside grapefruit seed extract and zinc. Surprisingly, I did not get sick, despite close contact with them. Another friend who used the same supplements recovered in a day and a half, whereas her family suffered for over a week. Now, I always keep lysine in my supplements.

6 people found this helpful

Ear Infection details

L-Lysine is my go-to supplement for viral infections, helping me recover faster and avoiding lingering colds. My daughters were to have their adenoids removed due to EBV but were advised against it. After taking L-Lysine alongside prescribed medication, EBV was no longer detected. I believe it played a significant role in our recovery.

L-lysine tablets are of good quality. The formulation provides remarkable results for my immune system and heart health; my headaches have ceased, and my energy has increased. The tablets are also easy to consume.

Headache details

Sexuality boost confirmed

Low Libido details

Super quality! I ordered this for herpes, and it works effectively. I didn’t realise the impact it could have on my sexuality until I began taking Lysine. My needs for sex increased significantly, along with enhanced libido and sensations. I wholeheartedly recommend it to women experiencing issues in this area.

KLS offers better sore throat relief

Sore Throat details

Passàli D, Volonté M, Passàli GC, Damiani V, Bellussi L. Efficacy and safety of ketoprofen lysine salt mouthwash versus benzydamine hydrochloride mouthwash in acute pharyngeal inflammation: a randomized, single-blind study. Clin Ther. 2001;23:1508.

We looked into how ketoprofen lysine salt (KLS) mouthwash stacks up against benzydamine hydrochloride (BH) for treating sore throats. In a single-blind study with 241 patients, both mouthwashes were used twice daily for seven days. Results showed that KLS provided longer-lasting pain relief and was better tolerated than BH. While both treatments had some side effects, significantly more BH users reported issues. Overall, it seems KLS might be the more effective option for soothing a sore throat.

Helps sore throat

Most Useful Review

Excellent! NOW Foods L-Lysine, 500 mg can help cure sore throat and boost appetite.

Updated: Apr 2025

Tonsillitis details

7 people found this helpful

A superb remedy, this lysine is far more effective than Solaray—I have experienced it myself. It's ideal for a regimen against the Epstein Barr virus, but it works best when combined with monolaurin and colostrum, and requires a long-term intake of at least three months. By the end of my second month, both my chronic tonsillitis and laryngitis vanished, and my thyroid gland is gradually recovering! Please note that on days five to ten, you may experience severe intoxication; do not discontinue use—taking a sorbent will help!

Acne details

G2 dendrimer supports acne solutions

Leignadier J, Drago M, Lesouhaitier O, Barreau M, Dashi A, et al. Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin. Pharmaceutics. 2023;15. doi:10.3390/pharmaceutics15082083

We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.

Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.

We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.

Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.

Smooth skin achieved

Most Useful Review

6 people found this helpful

Against Herpes, For Beautiful Skin! I recommend drinking it if you have cold sores or problem skin. You will see results in a month! I drink for a month, take a break, then have the next one. I'm very happy so far! My facial skin has become perfectly smooth, without redness and acne! I highly recommend it! Thank you if you like it! 🤗💛

Updated: Mar 2026

Anemia details

2 people found this helpful

I am using it as part of my treatment for anemia, as I have low hemoglobin and ferritin. Besides iron supplements and vitamin C, my doctor advised lysine, as I seem to lack protein, crucial for iron absorption. I've been using all these supplements for two months, and while I have not experienced side effects, my iron levels have returned to normal. Healing takes time, but I see a positive trend, and while I don’t believe lysine alone is responsible, it certainly helps.

Autoimmune Disorder details

RCI001 shows promise for Sjögren syndrome

Kang H, Jung YH, Moon J, Ryu JS, Yoon CH, et al. Efficacy of RCI001 as a Therapeutic Candidate in a Primary Sjögren Syndrome Mouse Model. Cornea. 2025;44:226. doi:10.1097/ICO.0000000000003696

We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.

Happy customer

Most Useful Review

1 people found this helpful

I ordered this for my sister - she is thrilled with the results and reported no side effects.

Updated: Mar 2026

Stroke details

Lysine is an essential amino acid not produced by the body but obtained through food. It helps with calcium absorption, boosts bone strength, and reduces the likelihood of osteoporosis. Furthermore, lysine may enhance heart health by supporting carnitine production and lowering the risk of heart disease and stroke. Stay healthy❤ Thank you for your thumbs up!

Ulcer details

Reduced ulcer frequency

Since using L-Lysine, the frequency of my mouth ulcers has dramatically diminished. Previously, I experienced them every week, but now only when I overexert myself. I take 1 gm twice daily for maintenance and 1.5 gm twice daily at the first signs of an ulcer, significantly shortening lesion progression.

Abscess details

CT-K3K7 shows promise for abscess

Based on 3 Researches

Li S, Shui Y, Ma J, Yuan Y, Jiang W, et al. Antimicrobial activity of CT-K3K7, a modified peptide by lysine substitutions from ctry2459 - A Chaerilus tryznai scorpion venom peptide. Toxicon. 2022;218:88. doi:10.1016/j.toxicon.2022.09.004

We explored the effects of a modified peptide, CT-K3K7, derived from scorpion venom on abscess treatment. This peptide, altered through lysine substitutions, exhibited stronger antibacterial properties and reduced inflammatory cell presence in mouse models infected with S. aureus and P. aeruginosa.

Our study found that CT-K3K7 effectively decreased infection severity by lowering both bacterial counts and abscess area. We noted that this peptide also struggled to induce drug resistance in bacteria, highlighting its potential as a novel treatment option. Overall, CT-K3K7 seems promising for tackling abscess-related infections.

Amazingly effective

Most Useful Review

5 people found this helpful

Previously, I experienced monthly outbreaks of herpes labialis. Since I began taking lysine, with one tablet in the morning and one at night, the frequency has drastically reduced. On occasions when symptoms appear, I increase my intake, and the blisters tend to dry up without significant swelling. The results are impressive, and I consider it an essential supplement for managing my herpes.

Updated: Mar 2026

Adenoiditis details

Effective against EBV

6 people found this helpful

L-Lysine is my top supplement for any viral infection. It helps me recover faster and avoid lingering colds or complications. My daughters were set to have their adenoids removed, but due to contraindications from an EBV (Epstein-Barr virus) finding, they couldn't. L-Lysine was taken alongside prescribed medications after which EBV was no longer detected. I believe L-Lysine was very beneficial in our situation.

Cardiovascular Disease details

ZGCD improves diabetic cardiomyopathy

Ji K, Han M, Yang M, Xu Q, Zhang Y. Integrated meta-analysis and network pharmacology analysis: evaluation of Zhigancao decoction as treatment for diabetic cardiomyopathy. Front Cardiovasc Med. 2025;12:1454647. doi:10.3389/fcvm.2025.1454647

We examined how Zhigancao Decoction (ZGCD) affects diabetic cardiomyopathy (DCM), aiming to uncover its clinical benefits and underlying mechanisms. After analyzing numerous studies, we found that ZGCD significantly improves cardiac function and reduces blood pressure more effectively than conventional treatments. Additionally, it appears to have fewer side effects. The positive effects are likely linked to its ability to influence the AGEs-RAGE signaling pathway, boost lipid metabolism, and reduce atherosclerosis. However, it's important to note that more research is needed to fully understand these mechanisms.

Strong antiviral effect

Most Useful Review

542 people found this helpful

Excellent antiviral and immunomodulating agent. L-Lysine boasts a more than 95% effectiveness in treating viral diseases compared to 50-80% for antiviral drugs, regardless of the disease stage. Even in cases where it’s less effective, it prevents disease progression and enhances overall well-being. Additionally, it improves brain function and increases stress resilience.

Updated: Apr 2025

Celiac details

Improved skin condition

Good health to everyone! Everything is of high quality and positively affects health. The smell is neutral, making it suitable for the whole family. I appreciate this product; it improves skin condition and gives it a smooth, appealing look. It's completely natural and not tested on animals! Importantly, it does not contain gluten! I ordered this brand without regret. I've noticed improvements in my health, including a slight weight gain, which is important for me, and new hair has started to grow. At 54 years old, I wholeheartedly recommend it!

Chronic Fatigue Syndrome details

My doctor recommended I take L-Lysine 500 mg twice daily for my Epstein-Barr virus, alongside monolaurin and quercetin. After five months, my energy levels have greatly improved. I may reduce my dosage soon, but I will continue with L-Lysine.

Significant benefits observed

Tendonitis details

2 people found this helpful

L-lysine is an essential amino acid that I take for my tendons and bones. I've noticed a significant reduction in leg pain. The main benefits of L-lysine include: 1) aiding collagen formation; 2) normalising joint mobility; 3) alleviating joint pain; 4) enhancing dental health; 5) reinforcing the tendon structure; 6) accelerating wound healing; 7) increasing blood flow to muscles; 8) playing a crucial role in fat metabolism and energy production; 9) ensuring normal cardiovascular function. It's extremely beneficial for the entire body.

Cold details

Lysine aids cold adaptation mechanisms

Likely Very Effective

Xue C, Zhu S, Li Y, Chen X, Lu L, et al. Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation. Environ Int. 2024;192:109015. doi:10.1016/j.envint.2024.109015

We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.

We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.

In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.

7.5

Less outbreaks

Most Useful Review

60 people found this helpful

My last cold sore was 1.5 years ago. Since I started these supplements, I've experienced very few outbreaks, with the last being minor. I believe this product works, and I recommend taking it daily for anyone who suffers from cold sores.

Updated: Apr 2025

Flu details

Avoided flu effectively

323 people found this helpful

I have been taking one vitamin in the morning on an empty stomach for three months. I noticed the effects right away. The redness in my eyes has gone, and my hair has been falling out less. My menstrual cycle became more abundant and regular after stopping hormonal pills. Remarkably, when my husband fell ill, I managed to avoid the flu, indicating an antiviral effect, which is very encouraging! Lysine also aids in collagen production and helps maintain youthfulness. I plan to take a break before repeating the three-month course. The benefits of lysine for me have been tremendous; it exceeded my expectations.

Hair Loss details

L-lysine shows mixed results

Rushton DH. Nutritional factors and hair loss. Clin Exp Dermatol. 2002;27:396.

We delved into the connection between nutritional factors and hair loss, especially focusing on l-lysine. The study revealed that while a variety of nutrients influence hair health, l-lysine stood out as potentially beneficial. A double-blind study showed that many women experiencing increased hair shedding responded positively to treatments combining l-lysine with iron.

However, the research also highlighted that there is no strong evidence linking low zinc levels to hair loss. Overconsumption of supplements could even worsen hair loss if no deficiency is present. Overall, while nutrition plays a role, proper hair care and understanding the hair cycle are equally significant.

Effective for hair loss

Most Useful Review

1 people found this helpful

Use it as advised by Dr. Berg; it is excellent for the issue of hair loss and is taken on an empty stomach.

Updated: Apr 2025

Rash details

7 people found this helpful

A truly effective amino acid, verified by my personal experience. I have herpes type 1.2, and upon onset of symptoms, I took one tablet on an empty stomach, half an hour before meals. Within a day, the herpes had diminished, and after four days, my skin was clear without any rash. I'm extremely pleased with the outcome! Previously, I resorted to ointments and acyclovir, which were harsh on my liver, but now I will exclusively use L-lysine. I highly recommend it!

Lysine improves herpes symptoms

Shingles details

Walsh DE, Griffith RS, Behforooz A. Subjective response to lysine in the therapy of herpes simplex. J Antimicrob Chemother. 1983;12:489.

We explored the effectiveness of lysine supplementation in treating herpes infections through a survey of 1,543 participants after a six-month trial. The findings revealed that a substantial 84% reported that lysine helped prevent recurrences or reduced the frequency of outbreaks.

Notably, only 8% of users described their symptoms as severe while taking lysine, compared to 79% who felt that way without it. Healing times improved significantly; 83% felt lesions healed in five days or less with lysine, while 90% said healing took longer without it. Overall, 88% regarded lysine as an effective treatment.

Outbreak resolved

Most Useful Review

4 people found this helpful

I faced a shingles outbreak all over my arm. I aggressively treated it with 5000 mg of this product daily, and within a week, the outbreak had completely subsided!

Updated: Mar 2026

Weight Loss details

Effective for weight loss

Good. It can be used for weight loss very effectively, the quality is very good, and it is a necessary supplement that can be combined with protein.

Cumulative health benefits

Depression details

7 people found this helpful

Lysine bolsters fat metabolism and energy production, while also supporting the immune system. After six months of combining it with L-carnitine, I’ve experienced a surge in energy, improved mood, and less stress. I feel more vigorous and resistant to illness, as if I’ve fortified my health against outside challenges.

Herpes details

L-lysine helps prevent herpes outbreaks

Questionable

Based on 3 Researches

Jamgochian M, Alamgir M, Rao B. Diet in Dermatology: Review of Diet's Influence on the Conditions of Rosacea, Hidradenitis Suppurativa, Herpes Labialis, and Vitiligo. Am J Lifestyle Med. 2023;17:152. doi:10.1177/15598276211026592

We explored how dietary changes and supplements impact skin conditions like herpes labialis. Specifically, we found that L-lysine can be effective as a preventive measure against herpes outbreaks. However, it doesn’t help shorten the duration of active lesions once they appear. Despite popular beliefs around diet's role in such conditions, we observed that high-quality evidence supporting dietary changes for other skin issues like rosacea is lacking. Additionally, certain vitamins and minerals showed promise in treating conditions like hidradenitis suppurativa.

Herpes free!

Most Useful Review

83 people found this helpful

Excellent! My frequent herpes outbreaks have disappeared. I take lysine 1-3 times daily, and I'm thrilled with the results.

Updated: Mar 2026

Osteoporosis details

NSD2 inhibition may reduce osteoporosis

Based on 3 Researches

He G, Ke Y, Yuan J, Zhang B, Dai L, et al. NSD2-mediated H3K36me2 exacerbates osteoporosis via activation of hoxa2 in bone marrow mesenchymal stem cells. Cell Signal. 2024;121:111294. doi:10.1016/j.cellsig.2024.111294

We explored the connection between NSD2 and bone health, specifically how it affects bone marrow stem cells in osteoporosis. By using advanced techniques, we found that NSD2 inhibits the growth of these cells, which is crucial for healthy bones.

In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.

Calcium absorbtion help

Most Useful Review

L-lysine is an amino acid essential for various functions in the body. It aids in protein synthesis and is a key component of muscles and bones. This amino acid enhances calcium absorption, thereby decreasing the risk of Osteoporosis. Additionally, it boosts immune function, supporting the body in fighting infections. L-lysine improves collagen synthesis, benefiting skin, hair, and nails while contributing to overall health.

Updated: Mar 2026

Cold Sores details

Lysine helps reduce cold sore outbreaks

Questionable

Based on 6 Researches

Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol. 1984;58:659.

We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.

Quick relief

Most Useful Review

2 people found this helpful

After just a few doses, my lip sore noticeably reduced. I'm really impressed by the quick results.

Updated: Mar 2026

Brain Tumor details

Many people on social media recommend lysine for improved brain function and focus. This is the third day of using it, and I have noticed no change. I will reassess it in a month and hope to see significant results.

This is an excellent medication that helps alleviate anxiety and effectively counters diarrhoea due to stress.

Diarrhea details

Bone Pain details