NOW Supplements Vitamin E

Yousefi-Nodeh H, Farshbaf-Khalili A, Sadeghzadeh Oskouei B, Jafarilar-Aghdam N, Kazemi-Zanjani N, et al. Curcumin and vitamin E improve hot flashes, lipid profile, and fasting blood glucose without any detrimental effect on the liver and renal function in postmenopausal women: A triple-blind placebo-controlled clinical trial. Health Care Women Int. 2024;45:1184. doi:10.1080/07399332.2022.2117815

Based on 4 Researches

Vitamin E reduces hot flashes

We conducted a study with eighty-four postmenopausal women to see how vitamin E affects hot flashes, among other health markers. The participants were divided into three groups and received either Vitamin E, Curcumin, or a placebo for eight weeks.

Our findings revealed that vitamin E significantly reduced the frequency of hot flashes by nearly one-third compared to those taking the placebo. This reduction was accompanied by improvements in several health indicators, including lower serum triglyceride levels and enhanced high-density lipoprotein (HDL) cholesterol.

Furthermore, vitamin E also showed positive effects on liver health markers. Overall, it appears that vitamin E is effective not only in alleviating hot flashes but also in improving some aspects of the lipid profile in postmenopausal women, without adverse effects on liver or kidney function.

Essential vitamin preparation

Most Useful Review

21 people found this helpful

I heard that it is effective for hot flashes and purchased it. I take 5 of 400mg and 2000mg a day. In the middle of the night, it suddenly became hot, waking me up twice with sweat on my head and neck, but it didn't heat up too much. During the day, I have no hot flashes and feel calm. Previously, I took Chinese herbal medicine for 3 months with no effect, but with Vitamin E, I saw improvements in less than a week.

Knee Pain details

9 people found this helpful

I have been taking five tablets a day for nine years. My knee pain and shoulder issues, which had plagued me for years, improved completely within a month, and I have had no symptoms since. It's superb.

Liver Disease details

Song Y, Ni W, Zheng M, Sheng H, Wang J, et al. Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study. Cell Rep Med. 2025;6:101939. doi:10.1016/j.xcrm.2025.101939

Based on 14 Researches

Vitamin E shows promise for MASH

We investigated the effects of a daily dose of 300 mg vitamin E for treating metabolic dysfunction-associated steatohepatitis (MASH). In our study, 124 non-diabetic individuals were randomly assigned to either vitamin E or a placebo.

The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.

Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.

Liver disease support

Most Useful Review

1 people found this helpful

It is an essential part of my daily routine. I struggled to find a product with a sufficient concentration of the ingredient. This supplement helps combat liver disease and provides antioxidant benefits. I have also noticed improvements in my skin. I definitely recommend it; it's a quality product, and the pills are a good size with no taste.

Alzheimer details

Vitamin E's potential in Alzheimer's

Pelczarski M, Wolaniuk S, Zaborska M, Sadowski J, Sztangreciak-Lehun A, et al. The role of α-tocopherol in the prevention and treatment of Alzheimer's disease. Mol Cell Biochem. 2025. doi:10.1007/s11010-025-05214-1

We sought to understand the potential role of α-tocopherol, a form of vitamin E, in preventing and treating Alzheimer's disease. Various research studies have indicated that this antioxidant might slow down the disease's progression or even reduce the risk of developing dementia. Our review delved into the biochemical mechanisms of α-tocopherol, highlighting its anti-inflammatory properties and ability to combat oxidative stress, which are vital in Alzheimer's pathology.

Interestingly, higher intake of α-tocopherol is linked to a lower incidence of mild cognitive impairment, suggesting its protective effects. However, we also noted that many people do not consume sufficient amounts of this vital nutrient. While there's a promising outlook for α-tocopherol supplementation as part of Alzheimer's management, we acknowledge that further research is necessary to draw definitive conclusions regarding its effectiveness and the mechanism behind its action.

Overall, our exploration into the relationship between vitamin E and Alzheimer's sheds light on a possible avenue for intervention, though clarity in treatment specifics and comprehensive studies are still required.

Alzheimer's treatment support

Most Useful Review

Vitamin E is an essential antioxidant vitamin that safeguards cranial nerves and possibly averts cataracts. It is fat-soluble and well-absorbed. I've found that it has a proven track record in aiding Alzheimer’s treatment, and I take it three times daily for its benefits.

Arthritis details

Reduces arthritis risks

Vitamin E is a powerful antioxidant that protects cells from oxidative damage. It strengthens the immune system, protects cells from premature ageing, reduces inflammation, and may lower the risk of diseases linked to oxidative stress, including arthritis, cataracts, and Alzheimer's disease.

Atrial Flutter details

No cardioversion needed

4 people found this helpful

For heart health, I take Vitamin E with every meal as recommended by my natural health sources. Recently, the hospital informed me that I no longer require cardioversion because my sinus rhythm is now normal. Just last month, I was diagnosed with atrial flutter. While Vitamin E isn't the only supplement I take for heart health, I believe it has significantly helped me.

Bruise details

Immediate healing effect

I found this product great for heart health. The quality and dosage are good, and I use the oil for bruises and cuts. It helps with immediate healing and promotes regeneration of the skin.

Chest Pain details

Chest pain improvement

2 people found this helpful

I mistakenly bought synthetic vitamin E, but this natural variant has proven very effective. My period was difficult, yet since using this, the pain in my lower abdomen has almost vanished.

Chronic Cough details

Relieved chronic cough

8 people found this helpful

As a supplement advisor, I've found this vitamin E supplement effective, especially because it contains mixed tocopherols rather than just α-tocophenol, which had previously aggravated my chronic cough. Since switching to this, I have experienced no such symptoms. It also aids blood circulation. Stiff shoulders have reduced significantly, which is notable since I work at a desk. Overall, I find it vastly superior to others I’ve tried.

Flu details

NOW Foods E-400 with Mixed Tocopherols is excellent! My wife and I take it daily as part of our immune system strategy. Alongside Vitamin E-400, we also supplement with Quercetin, zinc, Vitamin C, Vitamin D-3, Curcumin, Melatonin, and NAC. We find this combination a perfect prophylactic for upper respiratory viruses like the flu and Covid-19.

High Cholesterol details

Potential atheroprotective effects of T3

Based on 16 Researches

Rahman TA, Hassim NF, Zulkafli N, Muid S, Kornain NK, et al. Atheroprotective effects of pure tocotrienol supplementation in the treatment of rabbits with experimentally induced early and established atherosclerosis. Food Nutr Res. 2016;60:31525. doi:10.3402/fnr.v60.31525

We aimed to explore how pure tocotrienol (T3), a form of vitamin E, might help in fighting atherosclerosis, a condition often linked to high cholesterol. In our study, 30 rabbits were fed high-cholesterol diets and then divided into groups receiving different doses of T3 or a control without T3.

The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.

Improves blood circulation

Most Useful Review

48 people found this helpful

The key feature of this product is the inclusion of "mixed tocopherols". It contains 400 IU of alpha tocopherol and other tocopherols, which are beneficial for blood circulation. Small and easy to swallow, this product is great value, particularly for those sensitive to cold. This natural alpha-tocopherol is notably effective for improving blood flow and overall health.

Insomnia details

Countering insomnia effectively

I have taken 1200U nightly for three years to combat insomnia. After studying molecular nutrition, I use it to manage my condition without falling into the dependency on sleeping pills. Vitamin E is crucial for eliminating active oxygen to prevent cell damage. I believe these natural ingredients and megadoses of vitamins are vital to treating my insomnia effectively.

Rash details

Skin condition improved

After purchasing vitamins E and A from this company, I found that taking one each day is convenient as they are small and easy to swallow. Since I've recently been unwell, I began taking them immediately. These vitamins restore my respiratory tract's mucous membranes, act as excellent antioxidants, and boost my immunity. Most importantly, I've noticed an improvement in my skin condition. Rashes have virtually stopped appearing, wrinkles are beginning to smooth, and my skin feels more moisturised and radiant.

Swollen Lymph Nodes details

Reduction in swelling

Since I started drinking it, the swelling has diminished, and I feel fantastic!

Adenoiditis details

Natural tocopherol αβγδ mix is a fat-soluble vitamin. Taking it 3-4 times a week reduces my throat pain and decreases my chances of catching a cold. I believe this is due to the strengthening of my mucous membranes and immunity. This natural d-α tocopherol and αβγδ mix can be expected to have a synergistic effect. It’s a well-balanced form of vitamin E!

Anemia details

I constantly drink Vitamin E as it’s essential for supplying oxygen to the internal organs, especially in less-than-ideal environments. Factors like smoking and anemia can deprive organs of oxygen. Vitamin E compensates for this deficiency. I repeatedly order this product.

Arteriosclerosis details

Elbeltagy MAF, Elkholy WB, Salman AS. Effect of atherosclerosis and the protective effect of the antioxidant vitamin E on the rabbit cerebellum. Microscopy (Oxf). 2019;68:369. doi:10.1093/jmicro/dfz023

Based on 15 Researches

Vitamin E shows mixed effects

We examined the effects of vitamin E on atherosclerosis in the cerebellum of rabbits. In this study, forty rabbits were split into four groups, where specific groups received vitamin E alongside regular diets or added cholesterol.

The results revealed that cholesterol-treated rabbits experienced significant damage, evident through decreased fiber density and changes in brain cell structure. Surprisingly, while vitamin E showed some protective traits by reducing these changes, its overall impact on atherosclerosis was inconclusive.

Essential supplement

Most Useful Review

2 people found this helpful

Vitamin E is a fat-soluble vitamin with powerful antioxidant properties, preventing lipid oxidation and helping to avert arteriosclerosis and blood clots. It may lower blood pressure and reduce LDL (bad) cholesterol. Moreover, it keeps cell membranes healthy, potentially warding off age-related diseases, hence its title as the "rejuvenating vitamin." It is an essential supplement for my health.

Autoimmune Disorder details

Cholesterol reduction

I ordered this course alongside other medications to lower cholesterol levels. Currently, I am pleased with the results as my bad cholesterol is decreasing, although the course is not finished yet. My reaction to this vitamin E has been normal. It provides an excellent price-quality ratio.

Chronic Fatigue Syndrome details

Physical and mental well-being

After reading Dr. Tokumi Fujikawa's book, I incorporated vitamin E alongside Ferroquel and Vitamin B for chronic fatigue syndrome. I've been feeling fantastic both physically and mentally for about a year now.

Depression details

Since last year, I've been struggling with severe depression alongside PMS and PMDD. I've been practising megavitamin therapy, taking five tablets each morning. The tocopherol seems beneficial, and while the tablets are large, they're easy to swallow. I believe this therapy is effective in addressing my depression.

Heart Disease details

Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. doi:10.1016/j.ijcrp.2024.200340

Based on 12 Researches

Vitamin E linked to heart health

We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.

The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.

Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.

Heart disease protection

Most Useful Review

22 people found this helpful

Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.

Irritable Bowel Syndrome details

Menstrual pain relief

For menstrual pain, it works well. I noticed a significant difference in both premenstrual syndrome and menstrual pain during the month I took it compared to the month I didn’t.

Kidney Stones details

Supports kidney health

The quality of this product is excellent. The ingredients are thoughtfully chosen to assist kidney health. The size of the bottle is practical for storage and use. The recommended dosage fits easily into my daily routine. This product primarily supports normal kidney function and helps cleanse the body, and the neutral taste makes it comfortable to consume. Overall, it’s a sound choice for anyone concerned about kidney health and seeking an effective remedy for kidney stones.

Migraine details

Vitamin E aids menstrual migraine relief

Based on 4 Researches

Ziaei S, Kazemnejad A, Sedighi A. The effect of vitamin E on the treatment of menstrual migraine. Med Sci Monit. 2009;15:CR16.

We took a closer look at how vitamin E might help women suffering from menstrual migraines. In a double-blinded, placebo-controlled study with 72 participants, we compared the effects of vitamin E against a placebo over several months.

The results were promising, showing significant relief in headache severity and associated symptoms like photophobia and nausea when using vitamin E. Women reported less functional disability during this treatment. Overall, it appears that vitamin E could be a helpful option for managing menstrual migraines.

7.5

Reduced migraine frequency

Most Useful Review

5 people found this helpful

Very good cost performance! I’m taking this supplement alongside my girlfriend. Vitamin E is fat-soluble and difficult to overdose on, with just one tablet needed each day, making it easy to take. I've noticed it’s effective; my girlfriend used to suffer from severe migraines, but since she started this product, the frequency of her migraines has surprisingly decreased. I plan to continue using it!

Pelvic Pain details

Ziaei S, Zakeri M, Kazemnejad A. A randomised controlled trial of vitamin E in the treatment of primary dysmenorrhoea. BJOG. 2005;112:466.

Based on 13 Researches

Vitamin E reduces menstrual pain

We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.

Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.

Relieves menstrual pain

Most Useful Review

8 people found this helpful

Taking three tablets a day is quite a lot, but since I started, my pelvic pain during menstruation has been mild enough that I no longer need painkillers, and my menstrual flow has calmed down. After struggling for years, I am genuinely impressed by this significant change.

Tinnitus details

9 people found this helpful

Blurred Vision details

Enhancement of health

3 people found this helpful

I like the manufacturer but wish they noted the absence of GMOs. I'm very happy! I took four types of E; though I couldn't find non-GMO labels, I gave one star less. These vitamins are crucial—my body thanks me! I take them with A, C, and alternate with Astaxanthin. My skin improved in a week, and after two, it was much better: dryness and cracks healed, and my vision is clearer.

Bone Pain details

3 people found this helpful

I follow my therapist’s advice for circulation issues and varicose veins. This has been extremely helpful; I no longer suffer from leg pain, which is a great relief.

Constipation details

It's amazing, girls. I used to suffer from dryness in my skin and had dark circles under my eyes. Thankfully, since I started using it, the dark circles have decreased significantly, and my hair looks shiny. I even had constipation, which has now been resolved. Its effect is lovely; I feel it moisturises the inside of my body, and the package has plenty to last for months.

Leg Cramps details

Ayres S, Mihan R. Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol). Calif Med. 1969;111:87.

Based on 3 Researches

Vitamin E alleviates leg cramps

We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.

Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.

Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.

Effective for cramps

Most Useful Review

2 people found this helpful

I took Vitamin E for leg cramps prior to knee surgery, and it worked well for me.

Psoriasis details

This complex has successfully treated my psoriasis.

Acne details

No significant benefit of vitamin E

Based on 16 Researches

Kus S, Gün D, Demirçay Z, Sur H. Vitamin E does not reduce the side-effects of isotretinoin in the treatment of acne vulgaris. Int J Dermatol. 2005;44:248.

We explored the effectiveness of vitamin E alongside isotretinoin, a common treatment for severe acne. In an investigator-blinded, randomized study involving 82 patients, participants were divided into two groups. One group received isotretinoin alone, while the other combined it with 800 IU of vitamin E, over a period of 16 weeks.

Our main goal was to determine whether vitamin E could reduce the side-effects associated with isotretinoin, which are often bothersome for patients. Throughout the study, we assessed various mucocutaneous side effects, such as facial dryness and redness, as well as changes in serum lipid and liver enzyme levels.

Ultimately, we found no significant difference in the incidence or severity of side effects between the two treatment groups. This indicates that vitamin E did not provide any noticeable benefit when added to isotretinoin therapy for acne vulgaris.

While vitamin E is often suggested as a remedy to lighten the side effects of medications, our findings suggest that its use alongside isotretinoin may not be helpful.

No acne experienced

Most Useful Review

5 people found this helpful

Excellent vitamins! I'm very satisfied as my skin is now radiant. I had persistent acne before, but after three weeks of taking these vitamins, I no longer had any at all.

Back Pain details

Vitamin E shows promise for back pain

Likely Very Effective

Georges C, Lefaix JL, Delanian S. Case report: resolution of symptomatic epidural fibrosis following treatment with combined pentoxifylline-tocopherol. Br J Radiol. 2004;77:885.

We investigated the potential of vitamin E, when combined with pentoxifylline, in treating symptomatic epidural fibrosis, a common cause of persistent back pain after surgery.

A case study involving a patient suffering from chronic leg and back pain showed remarkable improvement after three months of this combined treatment over a period of 3.5 years.

By April 2001, he experienced total symptom regression, although residual fibrosis remained. This finding suggests that vitamin E could offer hope for individuals struggling with similar conditions, but more studies are necessary to validate these results.

Eased menstrual pain

Most Useful Review

2 people found this helpful

I was worried about the painful cramps during my period, but since I started taking vitamin E, the pain has lessened significantly and I feel better. The smaller grain size makes it easy to take.

Cancer details

Gamma-tocopherol in cancer research

Based on 14 Researches

Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, et al. Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Molecules. 2025;30. doi:10.3390/molecules30030653

We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.

In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.

Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.

While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.

Synergistic effects

Most Useful Review

89 people found this helpful

Vitamin E is vital for those practising Fujikawa's theory. High in antioxidants, it is expected to offer anti-aging benefits and cancer prevention. It enhances the effects of vitamins B and C when taken separately.

Cardiovascular Disease details

Vitamin E aids ischemic stroke recovery

Based on 14 Researches

Ishihara N, Tanaka M, Namba K, Kawano S, Nishimura S, et al. Long-term exposure to urban particulate matter exacerbates mortality after ischemic stroke in mice. J Toxicol Sci. 2025;50:147. doi:10.2131/jts.50.147

We investigated how long-term exposure to urban air pollution affects the recovery from ischemic stroke in mice. Our findings showed that breathing in fine particulate matter increases neuroinflammation and cardiac injury, leading to higher mortality rates after a stroke.

Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.

Aging prevention

Most Useful Review

22 people found this helpful

Vitamin E prolongs youth and beauty as it contains multiple tocopherols, with α-tocopherol being the most active. This powerful antioxidant stabilises cell membranes and interacts with vitamin C. Supplementing with tocopherols, such as those from NOW Foods, helps maintain health and appearance while preventing cardiovascular disease.

Eczema details

Vitamin E may aid eczema relief

Koczok K, Horváth L, Korade Z, Mezei ZA, Szabó GP, et al. Biochemical and Clinical Effects of Vitamin E Supplementation in Hungarian Smith-Lemli-Opitz Syndrome Patients. Biomolecules. 2021;11. doi:10.3390/biom11081228

We explored the effects of vitamin E supplementation on patients with Smith-Lemli-Opitz Syndrome (SLOS), particularly focusing on symptoms like eczema. In a three-year study, six patients who were already on dietary cholesterol treatment received vitamin E. Their vitamin E levels were initially low, but following supplementation, all patients showed a significant increase in plasma vitamin E concentrations.

Among the various symptoms assessed, including aggression, irritability, and skin issues like eczema, some patients reported improvements. Our findings indicated that three out of the six patients experienced a reduction in symptoms, including skin photosensitivity and eczema. Notably, those who responded best to therapy had lower baseline ratios of certain cholesterol-related compounds.

While the study suggests that vitamin E could provide benefits to SLOS patients—possibly contributing to improvements in skin conditions like eczema—individual responses varied. Thus, vitamin E supplementation may be worth considering in the management of SLOS, especially for those with low initial vitamin E levels and certain biochemical markers.

7.5

Skin healing effects

Most Useful Review

Superb quality. The large size offers great value. It works wonderfully for skin issues, including wounds and eczema. There’s no flavour which is an added benefit.

Frozen Shoulder details

Frozen shoulder relief

Since I began taking this product, my frozen shoulder has disappeared. As a parent, I often suffered from it while holding my baby, but I now have no discomfort, which I attribute to this supplement.

Hair Loss details

Vitamin E improves rabbit skin health

Moderately Effective

Based on 3 Researches

Waisburd GS, Cordero AM, Núñez CR, Contreras LM, Cárdenas RH, et al. Topical effect of a specific spot-on treatment made of natural ingredients in rabbits () with skin problems: A pilot study. Vet World. 2020;13:1760. doi:10.14202/vetworld.2020.1760-1763

We assessed the impact of a topical solution featuring essential oils, polyunsaturated fatty acids, and Vitamin E on rabbits facing skin diseases. The study included thirty New Zealand rabbits divided into two groups: one treated with the natural formula and a control group.

Over the treatment period, we observed notable improvements in hair shine, hydration, and a reduction in flaking, bad odor, and hair loss in the treatment group. In contrast, the control group showed no such benefits. Overall, this suggests that Vitamin E combined with other natural ingredients can enhance skin and hair health in rabbits.

Stopped hair loss

Most Useful Review

Great for hair and skin! This high-quality vitamin is excellent; my husband and I have been taking it for two months now. Our skin appears much more beautiful, nourished, radiant, and youthful. The benefits are expected to increase with prolonged use. My hair was shedding significantly after the "crown" (four months ago), but I'm pleased to report that the hair loss has stopped! The product's quality is exceptional, and the large packaging is economical. We take one capsule daily, which is easy to swallow. I highly recommend it!

Nausea details

I suffered from heavy menstrual cramps, headaches, and nausea. I've gradually increased my intake to 5 capsules, and I was surprised to find my cramps were nearly gone. When I missed a dose, the headaches returned, highlighting the effect of vitamin E. I believe vitamin C and vitamin K should be taken together.

Allergies details

Vitamin E in allergy treatment explored

Lu Y, Shan X, Huang J, Zhou H, Zhu Y, et al. Reductive Adjuvant Nanosystem for Alleviated Atopic Dermatitis Syndromes. ACS Nano. 2025;19:4195. doi:10.1021/acsnano.4c08767

We explored the potential of a specially designed nanoemulsion containing vitamin E to address the symptoms of atopic dermatitis (AD), a chronic skin condition that significantly impacts quality of life. In this study, the formulation, named PV-NE, aimed to balance the immune system and reduce inflammation characterized by the overproduction of reactive oxygen species (ROS), which are linked to worsening allergic reactions.

Through our research, we noted that while PV-NE demonstrated effectiveness in restoring immune balance and alleviating symptoms like itching and skin irritation, it did not isolate the effects of vitamin E specifically on allergies. Instead, the focus was on how the combination worked as a whole. This means that while vitamin E plays a role in the treatment via the nanoemulsion, we can't conclusively say it effectively treats allergies when considered on its own.

Ultimately, our findings establish a foundation for further exploration of vitamin E's contributions within broader therapeutic systems, indicating its biocompatibility and importance in future treatments for AD and potentially other allergies.

Essential for allergies

Most Useful Review

We take natural vitamin E regularly as a family. Its price and quality are excellent, and it’s indispensable for individuals with allergies and problem skin, complementing primary treatments. For women over 40, it is essential for maintaining a youthful appearance.

Blood Clot details

Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. Circulation. 2007;116:1497.

Based on 15 Researches

Vitamin E may reduce blood clots

We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.

Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.

Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.

Reduced blood pressure

Most Useful Review

33 people found this helpful

I had taken Vitamin E 400 units for 30 years but stopped three years ago. My blood pressure rose to 140 systolic, which was unusual for me. After recalling the benefits of Vitamin E, I switched to the NOW brand. Within two days of resuming, my systolic dropped below 120 and has remained stable since. Vitamin E helps keep arteries healthy as we age.

Common Cold details

Vitamin E's complex effects on colds

Based on 3 Researches

Hemilä H, Virtamo J, Albanes D, Kaprio J. The effect of vitamin E on common cold incidence is modified by age, smoking and residential neighborhood. J Am Coll Nutr. 2006;25:332.

We examined how vitamin E affects common cold incidence among different groups. In our study involving over 14,500 participants, we found that older smokers living in cities benefited from vitamin E, showing a 46% reduction in cold risk.

In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.

7.5

Enhanced warmth

Most Useful Review

6 people found this helpful

I take one tablet in the morning, one in the afternoon, and two in the evening. I feel my blood circulation improving. Notably, when I go to bed, my feet no longer feel cold, which helps me sleep.

Premenstrual Syndrome details

7 people found this helpful

My period pain has vanished, and I feel great. Since I started this regimen a month ago, I experienced my first month without menstrual pain or PMS. It feels incredible. I wish I had discovered this 10 years ago; my life has transformed. I plan to continue this journey to regain my lost health.

Headache details

Vitamin E alleviates menstrual migraines

Based on 5 Researches

Ziaei S, Kazemnejad A, Sedighi A. The effect of vitamin E on the treatment of menstrual migraine. Med Sci Monit. 2009;15:CR16.

We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.

The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.

Migraine frequency decreased

Most Useful Review

5 people found this helpful

I've been using this vitamin E supplement with my girlfriend. It has good cost performance, and since taking one tablet a day, my girlfriend's severe migraine headaches have significantly decreased. I plan to continue using it!

Menopause details