American Health Original Papaya Digestive Enzyme

Supplement Facts

Serving Size: 3 Tablets

Amount Per Serving

%DV

Calories

Total Carbohydrate

1 g

<1%**

Total Sugars

1 g

***

Includes 1 g Added Sugars

2%**

Calcium

157 mg

12%

Papain (from Papaya) (90,000 USP)

45 mg

***

Amylase (240 DU)

6 mg

***

Protease (from Papaya) (9,600 USP)

6 mg

***

Papaya Fruit (Carica papaya)

3 mg

***

The product is found useful for the following medical conditions

We explored the impact of Caricol®, a papaya preparation, on digestive issues, particularly constipation. In a double-blind, placebo-controlled study, volunteers suffering from chronic indigestion took either Caricol® or a placebo for 40 days.

Although participants reported significant improvements in constipation and bloating, these benefits did not persist after a washout phase. There was no substantial effect on heartburn due to the limited number of cases. Overall, while Caricol® showed promise, its long-term efficacy remains uncertain.

Relieves constipation

Most Useful Review

6 people found this helpful

Fast transfer speed. After a meal, I take 2 to 3 tablets, even after snacks and sweets. It aids in digestion, and now I feel comfortable without any discomfort or tiredness post-meal. Constipation is no longer an issue, and I feel lean and clean.

Updated: Mar 2026

Reflux details

Comfortable after-meals

Most Useful Review

21 people found this helpful

A few years back, I began experiencing bloating, reflux, and heart palpitations after every meal, regardless of my food intake. My doctor diagnosed me with GERD and prescribed antacids, but after suffering adverse effects, I sought alternatives. After discontinuing antacids for good, I discovered digestive enzymes were the solution! Taking these with another enzyme product means I can finally enjoy meals without distress, allowing me to relax after eating instead of agony. They come in convenient small doses, permitting flexibility for various meal sizes, which I prefer to swallow with water to protect my teeth.

Updated: Apr 2025

Flu details

SCIENTIFIC SCORE

Likely Very Effective

Based on 4 Researches

Promising vaccine approach for influenza

Carignan D, Thérien A, Rioux G, Paquet G, Gagné ML, et al. Engineering of the PapMV vaccine platform with a shortened M2e peptide leads to an effective one dose influenza vaccine. Vaccine. 2015;33:7245. doi:10.1016/j.vaccine.2015.10.123

We explored a new vaccine approach using papaya mosaic virus particles fused with a short influenza peptide. This innovative structure showed promise in generating strong immune responses after just one dose in mice. The results indicated that vaccinated mice were significantly protected from the flu, suggesting that this could pave the way for an effective, broadly protective vaccine. While the study used mouse models, the findings could provide insights into future influenza vaccine development.

Effective control

Most Useful Review

15 people found this helpful

I have suffered from severe acid reflux for over 11 years. I tried many times to come off medications like Omerazole only to return quickly. After a recommendation, I am so pleased with the results. I have finally managed to stop taking my standard medication and my symptoms are now completely under control thanks to this supplement. I'm a huge fan!

Updated: Mar 2026

Autoimmune Disorder details

9 people found this helpful

A miracle occurred—these vegetarian digestive enzymes are life-changing! After stumbling upon them online, I ordered and found that they truly work! After a few weeks of taking 1-3 tablets with food, I've noticed a significant improvement in my digestive health despite poor eating habits. They have a sweet taste and a strong fruity aroma. I’m delighted with this purchase and will definitely reorder!

Updated: Mar 2026

Bloating details

Short-term relief in digestion

Muss C, Mosgoeller W, Endler T. Papaya preparation (Caricol®) in digestive disorders. Neuro Endocrinol Lett. 2013;34:38.

We examined how the papaya preparation Caricol® impacts digestive issues like bloating and constipation in a double-blind placebo-controlled study. Participants with chronic digestive complaints took either Caricol® or a placebo for 40 days.

While we noticed significant improvements in symptoms of constipation and bloating for some participants, these benefits didn’t continue after the washout phase. Unfortunately, the treatment showed no lasting effect on heartburn. Overall, Caricol® may help some digestive issues but the benefits seem temporary.

Effective remedy

Most Useful Review

12 people found this helpful

These papaya enzymes are fantastic! I appreciate the favourable packaging and pleasant taste. They truly work to alleviate bloating and heaviness after overeating or eating something unsuitable. I've been loyal to this brand for three years now!

Updated: Mar 2026

Indigestion details

8 people found this helpful

Amazing! My husband has struggled with gastric issues for the entire four years we’ve been together. Last week, he complained that his stomach, even with Protonix, was causing him severe discomfort. I found this product, and after just one day, combined with Life Flora probiotics, his stomach pain vanished! He hasn't experienced any indigestion since starting this. It's a wonderful product that has truly saved his stomach!

Updated: Apr 2025

Gastroesophageal Reflux Disease details

Effective during exacerbations

Most Useful Review

6 people found this helpful

THIS IS FOR WHAT YOU CAN COME TO iHerb!! My rescuers, my helpers, and wellness-givers - THEY ARE MY FATHER!! I take them frequently (perhaps too much, I’m unsure), but during periods of exacerbation of Gastroesophageal Reflux Disease, they are my first saviours from heartburn and stomach discomfort. I confess that I sometimes dissolve them even on an empty stomach when heartburn strikes after eating, and they always help me. I truly hope that plant enzymes are not addictive, and I try to avoid taking unnecessary substances once the acute periods subside. But MY DADDERS ARE ALWAYS WITH ME!! Happy purchases to ALL! Your Mummy Lou.

Updated: Mar 2026

Liver Disease details

I introduced the whole family to these enzymes. They are a natural alternative to mezim without putting stress on the liver, especially following large family meals.

Updated: Apr 2025

Heartburn details

Papaya treatment shows mixed results

Muss C, Mosgoeller W, Endler T. Papaya preparation (Caricol®) in digestive disorders. Neuro Endocrinol Lett. 2013;34:38.

We analyzed the effectiveness of the papaya preparation Caricol® in treating digestive disorders, including heartburn, using a double-blind placebo-controlled design. Participants with chronic digestive issues took either Caricol® or a placebo for 40 days.

While we observed significant improvements in symptoms like constipation and bloating among early returnees, results for heartburn did not reach statistical significance due to a small sample size. Thus, while Caricol® supports digestive health, it may not effectively alleviate heartburn symptoms specifically.

7.5

Effective heartburn relief

Most Useful Review

228 people found this helpful

The best enzymes for my stomach health! These tablets are effective and really assist with overeating, soothing and relieving my heartburn. I usually take 2, but during heavy overeating, I chew 3 to alleviate discomfort faster.

Updated: Mar 2026

Celiac details

2 people found this helpful

Amazing! If you have IBS, you must purchase these! They are fantastic and great value for money. I also have a 3-year-old granddaughter who is highly sensitive to gluten, and even one slice of bread triggers diarrhoea. I provided a little container of these tablets to her mum, who noticed a dramatic improvement in her daughter. She now buys them too. I've been giving out these tablets to family and friends who complain of tummy ailments. I also keep a small container in the car for meals when I'm out and about.

Updated: Apr 2025

Food Poisoning details

SCIENTIFIC SCORE

Likely Very Effective

Papaya extract’s effect on S. aureus

Handayani L, Faridah DN, Kusumaningrum HD. Staphylococcal enterotoxin A gene-carrying Staphylococcus aureus isolated from foods and its control by crude alkaloid from papaya leaves. J Food Prot. 2014;77:1992. doi:10.4315/0362-028X.JFP-13-483

We investigated how a crude alkaloid extract from papaya leaves impacts Staphylococcus aureus, the bacteria responsible for food poisoning through its harmful enterotoxin A.

We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.

Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.

Daily digestive maintenance

Most Useful Review

11 people found this helpful

This enzyme has become essential for my gastrointestinal health. One tablet post-meal prevents any bloating or heaviness. I'm now able to enjoy any food without concern, and I hardly recall needing other digestive aids. The tablets are sweet and tasty.