Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as thiamine hydrochloride)
25 mg
2,083%
Riboflavin (as riboflavin 5'-phosphate sodium)
20 mg
1,538%
Niacin (as inositol hexanicotinate and nicotinic acid)
95 mg NE
594%
Vitamin B6 (as pyridoxal 5'-phosphate)
20 mg
1,176%
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt and calcium folinate]
680 mcg DFE (400 mcg)
170%
Vitamin B12 (as MECOBALACTIVE® methylcobalamin and adenosylcobalamin)
50 mcg
2,083%
Biotin
750 mcg
2,500%
Pantothenic Acid (as d-calcium pantothenate)
125 mg
2,500%
Choline (as choline bitartrate)
50 mg
9%
The product is found useful for the following medical conditions
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
We evaluated how D-Pinitol affects allergic rhinitis (AR) in a controlled study using mice.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
9.5
No allergies noted
Most Useful Review
Excellent complex with good forms of vitamins; it did not cause any allergies when I took it. I highly recommend it.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 10 Reviews
8.7
7
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
10
Increased energy
Most Useful Review
I don't feel tired after taking this product. I feel full of vitality and a burst of energy. There is no better remedy for fatigue than this.
Constipation details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.7
10
Constipation resolved
Most Useful Review
The quality is excellent, and the ingredients are top-notch. My health has improved, and the dosage is spot on. The packaging is good, and I've noticed benefits such as better digestion and enhanced microbiome function. My intestines work well, and constipation is now a thing of the past. The supplement is exactly what I needed, and I find the taste pleasant.
Anemia details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.4
USERS' SCORE
Good
Based on 4 Reviews
8.6
9.5
We explored the case of a 23-month-old boy diagnosed with Imerslund-Gräsbeck syndrome (IGS), a rare disorder causing severe anemia. This child showed significant blood cell reduction and poor growth, which led to investigations identifying two genetic variants linked to his condition.
Remarkably, vitamin B12 replacement therapy resulted in a strong recovery. This case highlights how vital it is to diagnose IGS early in cases of severe anemia, ensuring timely treatment to avoid long-term complications, including potential neurological damage.
Remarkably, vitamin B12 replacement therapy resulted in a strong recovery. This case highlights how vital it is to diagnose IGS early in cases of severe anemia, ensuring timely treatment to avoid long-term complications, including potential neurological damage.
10
Anemia resolved
Most Useful Review
None was making me feel better. Then, I was recommended by my doctors to take this complex B. Since then, it has been two years that my anemia is resolved, and I feel so much more energetic.
Blood Clot details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.6
8
We examined the effects of folic acid supplementation on blood clot events in patients with end-stage kidney disease (ESKD). Analyzing data from over 2,000 patients, we divided them into daily and weekly supplementation groups for a mean follow-up of 5.8 years.
Our findings indicated that patients receiving daily folic acid had a lower rate of arteriovenous access thrombosis compared to those on a weekly regimen. However, we found no significant differences between the groups concerning major cardiovascular events or overall mortality.
More research is needed to fully understand the potential of folate in preventing thrombosis in this population.
Our findings indicated that patients receiving daily folic acid had a lower rate of arteriovenous access thrombosis compared to those on a weekly regimen. However, we found no significant differences between the groups concerning major cardiovascular events or overall mortality.
More research is needed to fully understand the potential of folate in preventing thrombosis in this population.
9.5
Increased energy levels
Most Useful Review
This is a very good product! I've been using it for some time and truly feel the difference, particularly for my nervous system. After three months of taking this supplement, my blood tests showed that my B vitamin levels have improved, especially after a month-long break from it. It provides me with energy in the morning that lasts throughout the day. I’m quite a fan of the brand.
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
We examined the potential benefits of carnitine and folic acid in reducing bone pain and fatigue in patients with beta-thalassemia minor. Over three months, 73 participants received either carnitine alone, a combination of carnitine and folic acid, or folic acid alone, while a control group went without supplementation.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
9.5
Strengthened bones
Most Useful Review
These effective vitamins are reasonably priced with fast delivery. The quality is superb, and the small capsule size is convenient for use. I’ve noticed improvements in my immunity and bone strength. The excellent absorption ensures that deficiencies are covered. I highly recommend these vitamins to everyone; they are a very good supplement for the whole family. We consistently choose this product and recommend it to friends as well.
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.6
9.5
Pediatric migraine treatment with riboflavin
Our examination focused on the effectiveness of riboflavin, a form of Vitamin B2, in treating migraines in children and adolescents aged six to 18. We conducted a retrospective observational study involving 42 patients, where we measured the frequency, intensity, and duration of their headaches.
Remarkably, we found significant reductions in headache days per month, with intensity and duration also decreasing. Most importantly, riboflavin helped decrease the reliance on acute medication and fewer missed school days. We suggest this affordable treatment as a safe option for pediatric migraines.
Remarkably, we found significant reductions in headache days per month, with intensity and duration also decreasing. Most importantly, riboflavin helped decrease the reliance on acute medication and fewer missed school days. We suggest this affordable treatment as a safe option for pediatric migraines.
8.3
Symptoms disappeared
Most Useful Review
This is excellent in the complex. Thanks to our doctor Gulzhan Sabetovna, I am discovering new supplements at 60. I previously suffered from hot flashes, headaches, tinnitus, and irritability. After treatment, all these symptoms disappeared. I now have more energy, and life has become more enjoyable.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Positive impact noted
Most Useful Review
Fabulous! A high-quality product with perfectly selected ingredients that do not cause negative reactions. The large packaging ensures it lasts a long time, while the average capsule size has a neutral taste. Delivery was prompt and without damage. The formulation contains only useful and natural ingredients, including folic acid. I’ve noticed improved bowel function and metabolism, with significant results within a week. Additionally, my nervous system's functioning has improved, leading to reduced nervousness. The effectiveness of this vitamin is unquestionably evident.
Sleep Apnea details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Sound sleep achieved
Most Useful Review
This is a fantastic product! I take two capsules before bed, and I find I’ve been sleeping soundly until my alarm goes off in the morning. It has positively transformed my sleep patterns, and I wake up feeling refreshed.
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
10
No more ulcers
Most Useful Review
I can no longer get mouth ulcers.
Flu details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9.5
Strong and energising
Most Useful Review
This B-vitamin is potent. I have taken many B-vitamins over the years, and this one is strong and effective—it provides energy almost immediately. Although a lot tends to be flushed away, this one absorbs much better than most. It’s a great formula.
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Methylcobalamin protects against liver failure
We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.
In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
8.8
Energy boost
Most Useful Review
This complex has been well selected for my needs, eliminating the need to purchase each vitamin separately. It has small, convenient, tasteless capsules that provide energy; my liver feels its effects too. I'm now enjoying deep sleep, reflecting a positive impact on my nervous system. I'm delighted with this purchase and will continue buying it.
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Good
Based on 7 Reviews
8.2
8
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
8.8
Postpartum anxiety control
Most Useful Review
I never skip a day! A friend suggested this for my B deficiency symptoms, including postpartum anxiety. Within four days, I felt much better and noticed the difference if I didn't take it. My anxiety is more controlled, I'm clearer in thought, and I have plenty of energy. I look forward to seeing if this continued usage will benefit other symptoms.
Acne details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.1
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
8.8
Reduced acne
Most Useful Review
This active ingredient is very effective, making my skin less susceptible to acne while adding vitality.
