Doctor&#039;s Best High Absorption Magnesium Glycinate Lysinate

Magnesium sulfate aids pediatric asthma

Based on 4 Researches

Rower JE, Johnson MD, Zorc JJ, Shihabuddin B, Dai M, et al. Pharmacokinetics and Pharmacodynamics of Intravenous Magnesium Sulfate in Pediatric Acute Asthma Exacerbations. J Clin Pharmacol. 2025. doi:10.1002/jcph.6179

We explored how intravenous magnesium sulfate (IVMg) can help children facing severe asthma attacks. The study included 49 pediatric patients who were treated with IVMg after presenting to the emergency department. Some received a placebo, while others were given either 50 or 75 mg/kg of magnesium.

Our analysis showed that higher magnesium levels in the blood were linked to improvements in asthma symptoms, specifically reductions in the Pediatric Respiratory Assessment Measure scores. This suggests that IVMg could be an effective treatment for moderate to severe asthma exacerbations in children.

Interestingly, we noticed that only two out of 31 participants experienced hypotension, showcasing the safety of IVMg, as severe side effects are rare. Moreover, we proposed that a total serum magnesium area under the concentration-time curve greater than 63.1 mg h/L might be a useful target for effective dosing. Further research in larger studies is necessary to confirm these findings, but they indicate that IVMg could serve as a beneficial adjunct treatment for young patients suffering from asthma attacks.

Enhanced energy levels

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68 people found this helpful

I have been using this vitamin for over six months now and I honestly cannot live without it. It has been a tremendous help with my allergies, asthma, and fatigue. I feel such an incredible boost of strength and energy after taking this supplement that I cannot imagine how my day would be without it!

We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.

Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.

Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.

9.5

Effective pain relief

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26 people found this helpful

I recommend this supplement for arthritis in the knees. After enduring several surgeries and experiencing unbearable pain, I noticed an unbelievable difference just four days after starting this supplement. It provided me with significant relief, better than any painkiller I’ve tried, and restored my knee movement. I truly wish I’d discovered this 40 years ago.

Bruise details

Magnesium reduces bruising post-surgery

Likely Very Effective

Zou P, Zhang K, Jin Y, Liu G. The Efficacy of Magnesium Sulfate (MgSO4) Wet Dressing in Reducing Eyelid Swelling and Bruising after Blepharoplasty: A Randomized, Controlled, and Observer-Blinded Assessment Study. Facial Plast Surg. 2024;40:46. doi:10.1055/s-0043-1767768

We explored the impact of magnesium sulfate (MgSO4) wet dressings on bruising and swelling following blepharoplasty, a common eyelid surgery. In our study, fifty-eight patients were evenly split between two treatments: one side received a magnesium sulfate solution, while the other was cooled with ice packs. This setup allowed us to compare the effectiveness of these two methods objectively.

Over the recovery period, we observed that the eyelid swelling was similar in both groups initially but notably reduced over time. However, by the fifth day after surgery, we found that those treated with the magnesium solution experienced significantly less swelling compared to the cooling method. Additionally, bruising—measured by both area and incidence—was also lower in the magnesium group, highlighting its effectiveness.

Interestingly, a significant majority of patients preferred the magnesium treatment over ice cooling, with many appreciating the convenience and results of the wet dressing. This suggests that magnesium sulfate is not only effective in reducing bruising and swelling but is also a patient-favored option for recovery after eyelid surgery.

Less swelling noted

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3 people found this helpful

Helps with edema! The top form of magnesium! Taking 2 tablets at bedtime significantly reduces swelling by the morning, and the bruises beneath my eyes have lightened. I highly recommend it! Entering 0954 without gaps gives a discount of up to 10%.

Gastritis details

Improved muscle tension

27 people found this helpful

This chelated magnesium remarkably alleviates my persistent muscle tension in my back and neck, enhancing sleep quality and reducing anxiety. Even with my absorption issues stemming from gastritis, I find this magnesium easily digestible and effective. It significantly improves my overall well-being.

Gastroenteritis details

The BEST! This is the finest form of magnesium you can take. There are no gastro side effects, and I noticed its effects within days.

Gout details

Magnesium may protect against bone erosion

Based on 2 Researches

We examined the relationship between magnesium levels and the occurrence of bone erosion in patients with gouty arthritis. In our analysis, we observed that 769 gout patients were studied, allowing us to classify them into groups based on their serum ionized magnesium levels.

The results were striking: those with lower magnesium levels had a significantly higher rate of bone erosion. Specifically, patients in the lowest magnesium group showed a bone erosion prevalence rate of over 60%, compared to less than 45% in those with higher magnesium levels.

Our findings suggest that maintaining adequate levels of magnesium might offer a protective effect against bone deterioration in gout arthritis. This points to the possibility that magnesium supplementation could be beneficial for preventing or slowing down bone erosion in these patients.

Gout relief

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1 people found this helpful

An important mineral. Unfortunately, many people in our country suffer from magnesium deficiency. I purchased this for my family and me. It has alleviated various symptoms, especially for my son, who had gout symptoms. Since he began taking it, he has not had another crisis. Very good!

Influenza details

I’ve purchased the fourth jar from this site! My physician recommended chelated magnesium to combat sleep issues after cancer. I take two tablets at night and occasionally an extra one during the day. The results are distinctly positive! Chelated magnesium effectively alleviates leg cramps and benefits athletes’ muscles. It's also excellent for thinning the blood, crucial for treating the respiratory system after battling influenza viruses and coronavirus! The quality of this brand is outstanding! I'm grateful for this product and will exclusively purchase from iHerb.

Liver Disease details

Liver restoration noted

1 people found this helpful

I have been ordering this magnesium for three years and have found it beneficial in clearing my gallbladder and restoring my liver. Extremely satisfied and would highly recommend it.

Multiple Sclerosis details

Magnesium biotin enhances remyelination

Yulug B, Kilic E, Oğuz T, Orhan C, Er B, et al. Dose-Dependent Effect of a New Biotin Compound in Hippocampal Remyelination in Rats. Mol Neurobiol. 2025. doi:10.1007/s12035-025-04686-y

We investigated the potential benefits of magnesium in the form of a new compound, magnesium biotin (MgB), on remyelination in rats with induced demyelination. This is particularly relevant for conditions like multiple sclerosis (MS), where demyelination plays a critical role in disease progression. Through our study, we compared MgB's effects to those of standard biotin.

Our findings revealed that MgB significantly enhanced the remyelination process compared to biotin alone. Both treatments showed a dose-dependent improvement in spatial memory, indicating benefits for cognitive functions. Additionally, MgB treatment led to reduced levels of inflammatory proteins, an effect that was more pronounced at higher doses.

Notably, we discovered that MgB helped restore important proteins involved in neuronal function and transmission, such as Synapsin-1 and PSD-95, which are crucial for healthy brain functioning. We also observed an increase in beneficial brain-derived factors and a notable reduction in markers of reactive gliosis, which suggests a reduction in harmful inflammation.

The evidence indicates that combining magnesium with biotin could provide a more effective treatment strategy for promoting myelin repair in demyelination-driven conditions like MS. Our results support the potential for further research into using MgB in clinical settings for MS patients.

Eliminated muscle tension

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1 people found this helpful

I no longer feel sore! I had been suffering from severe low back pain for months and, after starting this supplement, the pain vanished within two weeks. Since then, I've returned to weight lifting and cardio without feeling sore. This has also significantly improved my sleep, which had been disrupted before. However, the tablet size is rather large.

Toothache details

Relieves various pains

This is the best magnesium for its price, offering fantastic quality! Dr. Best's magnesium is remarkable and truly effective! It assists with toothache as well as headaches and muscle pain. I recover more quickly after exercising! I highly recommend it.

Arteriosclerosis details

Prevent arteriosclerosis

The efficacy of magnesium can avert the formation of arteriosclerosis and enhance blood supply to the myocardium, while also protecting the cardiovascular system from damage. It improves calcium absorption and supports overall health, mental clarity, nutrient absorption, and muscle endurance. A deficiency in magnesium may lead to osteoporosis in patients.

Cancer details

Magnesium alloy inhibits cancer growth

Ouyang Y, Cao L, Zhao Q, Yang W, Lin C. Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Biomed Mater. 2025. doi:10.1088/1748-605X/adb2cc

We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments.

In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.

Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.

With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.

Recommended for cancer

Most Useful Review

I've been taking this for a few months now; it’s my second purchase. As a cancer patient, my magnesium levels were low, and my doctor advised long-term use. I found this product on IHerb and can highly recommend it.

Carpal Tunnel Syndrome details

Magnesium shows mixed effectiveness

Fialová J, Bartousek J, Nakládalová M. Alternative treatment of the carpal tunnel syndrome. Cent Eur J Public Health. 1999;7:168.

We explored the effects of a combined infusion therapy including magnesium on carpal tunnel syndrome (CTS) in a group of 101 patients who physically worked with their hands. The study utilized a retrospective design, looking back at participants who presented with abnormal nerve function shown through electromyography (EMG).

Within the study, we discovered that the patients' work environments varied widely, with many exposed to hazardous conditions like excessive vibrations. After treatment, 144 out of 166 diagnosed CTS cases showed improvement, suggesting that the combination therapy—including magnesium—could be beneficial for some patients.

When examining specific outcomes based on the severity of CTS, we noticed that patients with mild symptoms improved by an average of 61%, while those with moderate and severe conditions improved by 47% and 50% respectively. Despite these findings, we need to acknowledge that there was no significant difference in treatment outcomes related to age, sex, or symptom severity.

Interestingly, the results highlighted a portion of patients who did not improve or even experienced worsening symptoms. This raises questions about the effectiveness of magnesium and the combined treatment approach. Therefore, while magnesium plays a role in managing CTS for some individuals, it does not guarantee success for everyone.

Joint pain relief

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21 people found this helpful

I find this magnesium the most beneficial for easing my joint pain associated with Carpal Tunnel Syndrome and Hashimoto's. Other forms of magnesium do not work as effectively for me. The tablets are quite large, but that doesn't bother me; you could always break them in half if you dislike taking tablets.

Colitis details

Cui J, Li Y, Jiao C, Gao J, He Y, et al. Improvement of magnesium isoglycyrrhizinate on DSS-induced acute and chronic colitis. Int Immunopharmacol. 2021;90:107194. doi:10.1016/j.intimp.2020.107194

Based on 7 Researches

Magnesium's effect on colitis

We investigated the potential benefits of magnesium isoglycyrrhizinate in treating colitis induced by dextran sulfate sodium (DSS). Our findings suggest that magnesium isoglycyrrhizinate can effectively alleviate both acute and chronic symptoms of colitis.

The treatment helped reduce inflammation by lowering the number of immune cells in the affected areas and decreasing levels of inflammatory cytokines. Additionally, we noted it significantly reduced reactive oxygen species (ROS) levels and mitigated the damage to the gut barrier associated with DSS treatment.

Another key observation was the treatment's ability to decrease colonic fibrosis, a common complication of IBD. Overall, these results indicate that magnesium isoglycyrrhizinate shows promise in managing intestinal inflammation and could be beneficial for people suffering from inflammatory bowel disease in clinical settings.

7.5

Reduced Colitis symptoms

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4 people found this helpful

After trying magnesium oxide and citrate with little effect, I found this magnesium to be the best. Over a couple of weeks, my leg cramps subsided, and my spastic colitis showed less activity. Additionally, my headaches stopped. It seems I was truly lacking magnesium in my body.

Eczema details

3 people found this helpful

The eczema has subsided, and my skin has become clearer. Just two days after starting the treatment, I fell asleep without removing my makeup, but when I woke up, my skin was still moist instead of rough. For many years, I was concerned that my body's eczema would worsen, but now the lumps have decreased and the itching has vanished. It seems quite effective, so I believe that continued use will lead to complete recovery. I’m optimistic!

Epilepsy details

1 people found this helpful

This product has been a lifesaver for my 10-year-old son who suffered from uncontrolled epilepsy for over six months. After trying this remedy, his seizures vanished. While it may not work for everyone, there is minimal risk in attempting it. I discovered that three capsules daily are effective, and we've successfully begun to reduce his medication intake, albeit slowly.

Frozen Shoulder details

Neck stiffness alleviated

64 people found this helpful

I suffered from severe chronic fatigue syndrome. Upon consulting a nutritionist, I learned I needed magnesium quickly, so I purchased this high-absorption type. Initially, I took the recommended dose, but it didn't help. However, increasing it to 2 tablets twice daily resolved my neck and shoulder stiffness entirely! I continue to use it due to my kidney stones.

Hives details

As someone with multiple chemical sensitivities, allergies, and fibromyalgia, finding supplements that don't induce inflammation, hives, or pain is challenging. This magnesium supplement hasn’t caused me any problems, which is rare, so I highly recommend it.

Hypertension details

Magnesium intake linked to reduced hypertension

Han M, Zhang Y, Fang J, Sun M, Liu Q, et al. Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. Hypertens Res. 2024;47:331. doi:10.1038/s41440-023-01439-z

We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.

We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.

These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.

Insulin Sensitivity

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4 people found this helpful

I always buy magnesium for my elderly mother with diabetes. It enhances tissue sensitivity to insulin and has helped lessen her reliance on insulin injections while keeping hypertension at bay. I recommend it especially for women.

Insomnia details

Magnesium improves elderly insomnia

Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.

We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.

Effective for insomnia

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575 people found this helpful

A fantastic product for stress, anxiety, and insomnia! Understanding magnesium formulations was initially confusing, but I found Magnesium Glycinate to be the best option. It calms the nervous system, helping with my insomnia and anxiety during the day. I began feeling its effects soon after starting, particularly at night when I needed help to fall asleep.

Lupus details

Magnesium improves lupus symptoms in mice

Verlato A, Laragione T, Bin S, Kim RH, Salem F, et al. Revised version with tracked changes oral Magnesium reduces levels of pathogenic autoantibodies and skin disease in murine lupus. BMC Immunol. 2024;25:58. doi:10.1186/s12865-024-00650-y

We explored the impact of magnesium on lupus by feeding MRL/lpr female mice either a standard or a high magnesium diet over nine weeks. The results showed that the mice on the high magnesium diet experienced fewer skin lesions and reduced pathogenic antibodies.

This suggests magnesium could have a protective effect against lupus symptoms. However, while magnesium treatment demonstrates some promise in improving certain disease markers, it is essential to remember that further research is necessary to confirm its effectiveness in humans.

Normalised sleep

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I ordered Magnesium to assist with my sleep problems caused by work stress and extreme fatigue. This product from Best Company has proven to be the best. After taking just one pill, I am grateful that my sleep pattern has normalised. I now enjoy deeper sleep because this formulation absorbs well. The packaging is generous and it has no taste.

Sciatica details

This works brilliantly! I've tried various brands of magnesium over recent months, and this one is equally effective. I take one to two tablets before bed as a muscle relaxant due to my sciatica and a sleep aid, and the results are remarkable! I highly recommend it.

Ulcer details

Magnesium citrate outperforms sodium phosphate

Berkelhammer C, Ekambaram A, Silva RG. Low-volume oral colonoscopy bowel preparation: sodium phosphate and magnesium citrate. Gastrointest Endosc. 2002;56:89.

We explored the effectiveness of magnesium citrate versus sodium phosphate for bowel preparation before colonoscopy. In our study, which involved over 600 patients, we found that magnesium led to superior bowel cleansing when taken a day prior. Additionally, sodium phosphate, especially when split into doses, showed better cleansing results compared to when taken all at once.

Importantly, we noted that sodium phosphate was associated with a higher occurrence of rectosigmoid ulcers compared to magnesium. Overall, magnesium citrate appears to be a better option for those preparing for colonoscopy.

Reduces cramping

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24 people found this helpful

I've been playing tennis for 6-7 hours on my days off and used to suffer from soreness. I bought magnesium to help, especially since I have a stomach ulcer. I started small and eventually increased my intake. It effectively relieved my soreness, and thankfully, I experienced no cramping, a welcome relief!

Whooping Cough details

For muscle strain, I am pregnant in my second trimester and endured a painful muscle strain following a cough for a month. After taking this supplement for just two days, the pain vanished! I highly recommend it. I've had it for three months and can assert it's the best supplement, providing quick relief for body aches, headaches, and muscle tension.

Alzheimer details

Magnesium's impact on Alzheimer's treatment

Liao W, Wei J, Liu C, Luo H, Ruan Y, et al. Magnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis. Neural Regen Res. 2024;19:2281. doi:10.4103/1673-5374.391310

We explored the potential benefits of magnesium-L-threonate for Alzheimer's disease, particularly how it interacts with the gut microbiome. In our study, we focused on a specific mouse model that simulates Alzheimer's by using double-transgenic groups expressing particular proteins associated with the disease. By administering magnesium-L-threonate, we aimed to see if it could improve cognitive functions and alter gut bacteria positively.

Our findings revealed that magnesium-L-threonate not only enhanced learning and memory but also significantly altered the balance of gut microbiota. We observed a reduction in the harmful bacteria Allobaculum, while beneficial strains like Bifidobacterium and Turicibacter increased.

Additionally, our research detected changes in serum metabolites linked to neurodegenerative diseases, strengthening the idea that magnesium could play a role in brain health by influencing gut health. Importantly, we also noted improvements in intestinal barrier function, indicating that magnesium-L-threonate might mitigate some effects of Alzheimer's by repairing gut-related issues.

Overall, we believe that magnesium-L-threonate holds promise as a therapeutic option in managing Alzheimer’s symptoms, emphasizing the intricate relationship between the gut and brain in this condition.

Alleviates symptoms

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4 people found this helpful

The best of the best! Researchers have shown that magnesium helps reduce blood clotting in type 2 diabetes patients, lowering thrombosis risk. Magnesium is the second most prevalent intracellular electrolyte after potassium and is crucial for numerous enzymatic reactions related to glucose metabolism and vascular functions. Recent studies suggest inadequate magnesium intake correlates with higher incidences of type 2 diabetes and cardiovascular ailments. My 74-year-old mother, who has type 2 diabetes, has been taking this chelated magnesium regularly. A diet rich in magnesium, such as that from Dr. Best, even eases Alzheimer's symptomatology. Some scientists even propose that a magnesium deficit in the brain may trigger Parkinson's disease. I sincerely hope this insight proves helpful!

Anemia details

Magnesium is vital for addressing anemia. While everyone knows that iron is beneficial for treating anemia, I appreciated this product because it contains quality, absorbable ingredients. My regular blood tests showed gradual improvement in my anemia, which encouraged me to purchase it.

Atrial Fibrillation details

Magnesium supplementation reduces atrial fibrillation

Wilson MG, Rashan A, Klapaukh R, Asselbergs FW, Harris SK. Clinician preference instrumental variable analysis of the effectiveness of magnesium supplementation for atrial fibrillation prophylaxis in critical care. Sci Rep. 2022;12:17433. doi:10.1038/s41598-022-21286-1

We wanted to understand the effectiveness of magnesium supplementation in preventing atrial fibrillation, a common heart rhythm issue in critical care patients. In our study, we looked at patient data from a single center, analyzing the varied practices of bedside nurses regarding magnesium treatment.

By examining the approach of individual nurses, we identified two groups: those who tended to be liberal with magnesium administration and those who were more restrictive. Through rigorous analysis, we found that magnesium supplementation was linked to a 3% decrease in the relative risk of developing atrial fibrillation. This suggests that implementing routine magnesium treatment could be beneficial for patients.

While our findings support the idea of using magnesium to help prevent atrial fibrillation, we recognize that more research is needed to determine the best serum magnesium levels for maximum benefit. Overall, our study offers promising insights into how magnesium can play a role in improving patient care in critical settings.

Successful magnesium treatment

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18 people found this helpful

I've suffered from atrial fibrillation for about five years and have tried numerous medications that affected my thyroid. Despite having RFA, I still felt interruptions in my heart. A cardiologist suggested magnesium, leading me to Doctor's Best. After taking it for three weeks, I've enjoyed sinus rhythm for over ten days without seizures, even after stress! I suspect my arrhythmia was due to magnesium deficiency.

Autism details

Magnesium linked to autism levels

Almalki AH, Bamaga AK, Alharbi A, Abduljabbar MH, Alnemari RM, et al. Exploring the association between serum magnesium level and autism spectrum disorder using validated spectrofluorimetric method. Anal Biochem. 2025;699:115755. doi:10.1016/j.ab.2024.115755

We aimed to understand the relationship between magnesium levels and autism spectrum disorder (ASD), shedding light on a critical nutrient’s role in brain health. To do this, we developed a unique analytical method to measure magnesium levels in the serum of both autistic and healthy children. Our approach used innovative technology involving fluorescent graphene quantum dots to detect magnesium, ensuring accuracy in our measurements.

Our findings revealed that children with ASD had significantly lower serum magnesium levels compared to their healthy peers. Specifically, they averaged 2.03 mg/dl of magnesium, while the healthy group had an average of 2.28 mg/dl. This noteworthy difference suggests a potential link between magnesium deficiency and ASD, indicating that enhancing magnesium levels might benefit autistic children.

Overall, our study emphasizes the importance of considering micronutrients like magnesium when addressing autism. While further research is necessary to fully understand the implications, our results provide a foundation for exploring magnesium supplementation as a supportive approach for those with autism spectrum disorder.

Calmer and attentive

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2 people found this helpful

Excellent! I bought this for a child with autism, and he became noticeably calmer and more attentive, with improved sleeping. Very satisfied.

Back Pain details

Magnesium reduces postoperative back pain

Based on 7 Researches

Celenlioglu AE, Sir E, Ors-Yildirim N, Yildirim AK, Ince ME, et al. Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting. J Vasc Surg Venous Lymphat Disord. 2023;11:517. doi:10.1016/j.jvsv.2022.09.008

We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.

Reduced back pain

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326 people found this helpful

Magnesium is superb! My husband and I notice a difference after just one week; our leg pain has vanished. My sedentary job had led to discomfort, but now we feel energised. We even bought a bottle for our parents, and they've felt the benefits too. If you appreciated my review, please put YES. Wishing you health!

Bone Pain details

CMT shows potential for pain relief

Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.

We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.

Improved quality of life

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720 people found this helpful

I am smiling at my boss and love my mother-in-law! For over two years, I've experienced symptoms like anxiety, fatigue, and constant headaches, which I attributed to a lack of magnesium. Initially, I hesitated to take it, thinking it was just an “age-old” remedy. However, magnesium supplementation has transformed me from a tired individual into a calm person. My meteorological dependence and tearfulness have vanished, and the quality of life has improved dramatically. I recommend magnesium for overall wellness and vitality.

Celiac details

Helps me fall asleep (gluten free for those with celiac). I take this before bed and it definitely aids my sleep. However, the pills are quite large and can be difficult to swallow. Since I have celiac disease, I am very sensitive but have had no adverse reactions to this supplement.

Fibromyalgia details

Magnesium potentially aids fibromyalgia

Based on 6 Researches

Macian N, Dualé C, Voute M, Leray V, Courrent M, et al. Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial. Nutrients. 2022;14. doi:10.3390/nu14102088

We conducted a randomized, controlled, double-blind study to determine the effects of magnesium on fibromyalgia symptoms. Our findings showed that magnesium supplementation did not lead to a significant reduction in overall stress levels compared to placebo.

However, we did find that magnesium significantly reduced mild to moderate stress and pain severity among participants. These results suggest that including magnesium in treatment could help alleviate some of the burdens fibromyalgia patients face.

This research indicates further exploration of magnesium’s potential should take place in larger studies.

Tremendous pain relief

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10 people found this helpful

MAGNESIUM TO THE RESCUE! Doctor's Best magnesium has tremendously helped with my fibromyalgia pain, and using Doctor's Best D-Ribose and 5 HTP together has been an excellent combination.

Hot Flashes details

Magnesium may ease hot flashes

Park H, Parker GL, Boardman CH, Morris MM, Smith TJ. A pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients. Support Care Cancer. 2011;19:859. doi:10.1007/s00520-011-1099-7

We set out to explore whether magnesium could alleviate the uncomfortable hot flashes experienced by breast cancer patients. In our pilot study, we enrolled women who reported having at least 14 hot flashes a week and administered magnesium oxide. The dosage started at 400 mg for four weeks, and we allowed it to escalate to 800 mg if necessary.

Among the 29 women who joined, 25 completed the treatment, with an average age of 53.5 years. We found that the frequency of hot flashes decreased significantly, dropping from an average of 52.2 per week to 27.7, which is a 41.4% reduction. The overall hot flash score, which combines frequency and severity, also showed improvement, reducing by over 50%. More than half of the participants reported that their hot flashes had decreased by more than 50%, and nearly three-quarters experienced at least a 25% reduction.

Side effects were minimal, with only a couple of women discontinuing the treatment due to headache and nausea. Overall, compliance was excellent, and many participants chose to continue taking magnesium even after the study ended. As such, the results suggest that oral magnesium could be a promising option for managing hot flashes, encouraging further research through a randomized placebo-controlled trial.

Reduces hot flashes

Most Useful Review

2 people found this helpful

I bought this for my mother during her menopause. It’s a good magnesium supplement! It alleviates frequent hot flashes and normalises mood, contributing positively to her overall sleep and wellbeing!

Menopause details

Magnesium aids menopause-related issues

Based on 8 Researches

Zhang J, Mai CL, Xiong Y, Lin ZJ, Jie YT, et al. The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice. J Inflamm Res. 2021;14:6633. doi:10.2147/JIR.S330894

We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.

We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.

Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.

In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.

Mood stabilisation noted

Most Useful Review

2 people found this helpful

I bought this for my mother during menopause. Good magnesium! It eliminates frequent hot flashes and normalises her mood, contributing to improved sleep and overall wellbeing.

Migraine details

Magnesium reduces migraine symptoms

Based on 21 Researches

Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.

Migraine relief

Most Useful Review

242 people found this helpful

I have been taking this wonderful medication for a year and a half, and during this time, I have eliminated my main issue - migraines.

Psoriasis details

Magnesium is excellent for psoriasis! It significantly reduces inflammatory processes associated with the condition. Adequate magnesium intake enhances joint mobility and alleviates pain. This mineral is particularly vital for those who suffer from arthritis related to psoriasis.

Urinary Tract Infection details

33 people found this helpful

OMG! The best product I've taken. The packaging is easy to open, and it does its job perfectly. I started sleeping through the night without waking up and have more energy than ever. I highly recommend this magnesium due to its exceptional absorption.

Athlete’s Foot details

45 people found this helpful

I'm very impressed with this magnesium! I take it regularly for myself and my mother, who works on her feet all day. She used to suffer from cramps at night, but now everything is fine. We appreciate the intermittent use and the health benefits it provides.

Brain Tumor details

Magnesium reduces brain injury markers

Mirrahimi B, Mortazavi A, Nouri M, Ketabchi E, Amirjamshidi A, et al. Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial. Acta Neurochir (Wien). 2015;157:985. doi:10.1007/s00701-015-2376-x

We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.

The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.

Life-changing effect

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106 people found this helpful

Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.

Chemotherapy details

93 people found this helpful

I am thrilled about this vitamin as it has been beneficial. I bought one for my sister, who was struggling during chemotherapy, and she's feeling better now. I also took it daily and feel great. The mild taste is another aspect I enjoy!

Hypothyroidism details

Rabbani E, Golgiri F, Janani L, Moradi N, Fallah S, et al. Randomized Study of the Effects of Zinc, Vitamin A, and Magnesium Co-supplementation on Thyroid Function, Oxidative Stress, and hs-CRP in Patients with Hypothyroidism. Biol Trace Elem Res. 2021;199:4074. doi:10.1007/s12011-020-02548-3

Magnesium shows potential benefits

We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.

In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.

However, no noteworthy changes were observed in the control group regarding thyroid hormones.

Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.

Calmness and relief

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5 people found this helpful

This product genuinely works well for my nervous system. After taking this magnesium alongside B vitamins, I achieved almost complete calmness. Caution is necessary to avoid overdosing, which can lead to lowered blood pressure; for me, it notably improved my stool regularity, a common issue with hypothyroidism. Although I experienced constipation previously, I needed to control my intake and had to stop after two weeks due to an accidental overdose. Nevertheless, I am pleased with the results and plan to order more.

Knee Pain details

Magnesium sulfate alleviates postoperative pain

Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. doi:10.1186/s13018-023-03790-w

We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.

Knee improvement noted

Most Useful Review

16 people found this helpful

Great value for money! This magnesium chelate, with glycine and lysine, promotes relaxation, especially when taken before bed. My knee arthrosis has improved significantly, and I wholeheartedly recommend it. If you find this helpful, please give it a like!

Low Libido details

After taking this with zinc, I noticed an increase in libido, and my beard feels sturdier to the touch, plus my nails are growing rapidly.

Pelvic Pain details

Magnesium alleviates primary dysmenorrhea

Based on 10 Researches

Benassi L, Barletta FP, Baroncini L, Bertani D, Filippini F, et al. Effectiveness of magnesium pidolate in the prophylactic treatment of primary dysmenorrhea. Clin Exp Obstet Gynecol. 1992;19:176.

We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.

The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.

Improved life quality

Most Useful Review

720 people found this helpful

I am smiling at my boss and I love my mother-in-law! Two years ago, I discovered symptoms such as muscle cramps and pelvic pain, which led me to consider magnesium. Initially dismissive, I soon realised that magnesium supplementation significantly enhanced my life quality, transforming me from an irritable person into a more balanced individual. My symptoms of meteorological dependence and tearfulness faded, making mornings much more pleasant. It's vital to test for magnesium deficiency, and one should take approximately 300-350 mg daily, which is difficult to obtain from food alone. I recommend magnesium chelates for better absorption.

Polycystic Ovary Syndrome details

High quality, clear ingredients, and an ideal size. It offers the best magnesium content for Polycystic ovary syndrome and sleep assistance.

Tendonitis details

Joint discomfort reduced

This has been a game-changer for my sleep quality. Since adding this to my routine, my sleep has become deeper and more restful, even better than melatonin for me. As a bodybuilder, joint health is vital, and this magnesium supplement has significantly helped. My elbow tendonitis disappeared in under three weeks, working better than any other mineral so far. The high absorption formula is impressive—I've felt the effects quickly, showing it's potent, especially compared to cheaper local options. It has also enhanced my cognitive function. Overall, it's an excellent supplement I highly recommend, having used it since 2021.

Tinnitus details

Magnesium's role in tinnitus explored

Based on 6 Researches

Uluyol S, Kılıçaslan S, Yağız Ö. Relationship between serum magnesium level and subjective tinnitus. Kulak Burun Bogaz Ihtis Derg. 2016;26:225. doi:10.5606/kbbihtisas.2016.87094

We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.

By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.

Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.

Quick recovery

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17 people found this helpful

Something few know about is that taking large doses of vitamin D3 can strip magnesium from your body. I experienced dizziness, blurry vision, and tinnitus for months before realising I needed magnesium. After taking high-quality chelated magnesium, I was completely fine within 48 hours. Most people should consider supplementing with magnesium, especially if taking large doses of vitamin D3.

Vertigo details

Likely Very Effective

Effective magnesium treatment for vertigo

Abouzari M, Abiri A, Djalilian HR. Successful treatment of a child with definite Meniere's disease with the migraine regimen. Am J Otolaryngol. 2019;40:440. doi:10.1016/j.amjoto.2019.02.004

We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.

After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.

Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.

7.5

Helps with dizziness

Most Useful Review

An excellent combination at a great price, it offers top quality. I found it beneficial for deep sleep, which is helpful for the body, and it is particularly useful for certain cases of dizziness, namely vertigo.

Adrenal Gland Disorder details

Improved sleep quality

6 people found this helpful

I purchased this to help with adrenal gland disorder, anxiety and as a sleep aid. Suffering from adrenal gland disorder results in chronic fatigue, insomnia, anxiety, and muscle loss. This product has the highest absorption rate I've found at a great price. One tablet taken about 45 minutes before bedtime helps me sleep through the night and wake up refreshed. I believe it’s effective and calming my nervous system. I’ll continue to reorder from iHerb, as their price is the best I’ve come across.

Angina details

Magnesium deficiency linked to angina

Based on 4 Researches

Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.

We set out to understand how magnesium levels relate to the frequency of chest pain in women suffering from variant angina. By assessing the magnesium status in twelve participants, we divided them into two groups: those experiencing four or more angina attacks per week, and those with fewer.

Through a magnesium loading test, we discovered that women in the group with higher attack frequency had a significantly higher retention of magnesium. They also showed lower intracellular magnesium levels in their red blood cells. This suggests a clear deficiency in magnesium amongst those experiencing more frequent chest pain.

Our findings indicate a strong correlation: as magnesium levels in the cells decreased, the frequency of angina attacks increased. This suggests that addressing magnesium deficiency may be crucial for women dealing with variant angina and experiencing chest pain more frequently.

7.5

Effective pain relief

Most Useful Review

55 people found this helpful

I have tried various remedies for my constitution and my mother’s panic disorder, but magnesium has had an immediate effect. My body has been getting weaker due to my job, and I often woke up at night with pain. After taking magnesium, I am now completely pain-free. I have also managed to deal with my vasospastic angina attacks, which I’ve been controlling with nitroglycerin for years. This has been a dramatic bonus for me. I can feel how effective it is for my nerves and muscles. I’m feeling much better now, and I hope it will benefit my mother’s mental health as well.

Chest Pain details

Magnesium improves chest pain outcomes

Based on 19 Researches

Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.

We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.

Continues to work

Most Useful Review

14 people found this helpful

I take magnesium transdermally and orally. After I stopped, I began experiencing leg cramps. However, once I resumed taking magnesium, the chest pain ceased. I intend to continue its use as I find it helpful. Capsules are easier to swallow, albeit manageable. Sometimes, I feel it might be stuck in my throat, so I drink carefully.

Leg Cramps details

Barna O, Lohoida P, Holovchenko Y, Bazylevych A, Velychko V, et al. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps. Nutr J. 2021;20:90. doi:10.1186/s12937-021-00747-9

Likely Ineffective

Based on 17 Researches

Magnesium oxide treats leg cramps

We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.

Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.

The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.

High digestibility

Most Useful Review

418 people found this helpful

Excellent magnesium with very high digestibility. I take it at night, two hours before bed. It has completely resolved my night leg cramps.

Cholecystitis details

5 people found this helpful

I absolutely love magnesium, particularly this brand. The dosage is ideal, allowing me to adjust the number of tablets as needed. My life transformed dramatically after I started taking magnesium, which is crucial for about 300 enzymatic reactions in the body. It's vital for stress reduction, alleviating spasms, and improving bile flow, especially since I've had my gallbladder removed. Normalising gastric acidity is also key for absorption. Consulting a doctor is advisable for the best results.

Chronic Fatigue Syndrome details

Magnesium potentially benefits CFS patients

Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.

We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.

Irritability reduced

Most Useful Review

189 people found this helpful

This magnesium has been incredibly effective for me. It alleviated my irritability and fatigue, allowing me to fall asleep much more easily. It appears to have a cumulative effect, so consistency in taking it is key.

Cold Sores details

31 people found this helpful

The best sleep! Why didn't I drink this brand sooner? I'm grateful I discovered it. After drinking, I felt instant comfort and was able to fall asleep and have a good night's rest. My toes became warmer, and my sensitivity to cold improved. I regularly use it, especially in combination with magnesium oil. Please refer to my other reviews for more details. Thank you for your consideration.

Ear Infection details

Improved sleep quality

18 people found this helpful

Years ago, I neglected my health, but after getting back into fitness, I discovered a magnesium deficiency. I started taking a supplement for it and saw a remarkable improvement in my insomnia within two weeks. I’m thrilled with how quickly things have improved and can't wait to see the long-term results.

Obesity details

Chromium is vital for normal fat metabolism; a deficiency often leads to excess weight and obesity. It aids the thyroid gland's function, contributes to immune system formation, and influences tissue growth and regeneration. I was prescribed this by my endocrinologist!

Stroke details

Magnesium shows neuroprotective promise

Based on 15 Researches

Zhang Y, Zhang H, Jiang M, Cao X, Ge X, et al. Neuroprotection on ischemic brain injury by Mg/H released from endovascular Mg implant. Bioact Mater. 2024;42:124. doi:10.1016/j.bioactmat.2024.08.019

We embarked on an intriguing exploration of how magnesium might help during cerebral ischemia, particularly after an acute stroke. The study set out to determine the potential benefits of a biodegradable neuroprotective stent that releases magnesium into the bloodstream, targeting areas impacted by reperfusion injury.

To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.

Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.

In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.

Improves recovery post-stroke

Most Useful Review

4 people found this helpful

This product has been excellent for someone who has suffered a stroke. Observations suggest significant improvements in mood and memory from the patient's perspective, particularly when comparing conditions before and after starting treatment. We combine it with other natural remedies, and though I can't pinpoint the exact factor, the overall effect is remarkable, and I highly recommend it to anyone facing similar challenges.

Depression details

Magnesium intake reduces depression risk

Hajhashemy Z, Shirani F, Askari G. Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis of Epidemiologic Studies. Nutr Rev. 2025;83:217. doi:10.1093/nutrit/nuae056

We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.

Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.

Effective depression relief

Most Useful Review

69 people found this helpful

I take it to relieve symptoms of depression. I'm surprised by the clear effects; I had a terrible experience in psychiatry and prefer controlling my mental state with magnesium now. It’s critical not to exceed 300mg daily since I’ve read that long-term use of ineffective psychotropic medications can shorten life expectancy. I feel empowered with magnesium and find it more effective than psychosomatic treatments.

Diabetes details

Magnesium intake benefits diabetes patients

Based on 19 Researches

Huang R, Kong X, Geng R, Wu J, Li J, et al. Associations of dietary magnesium intake with the risk of atherosclerotic cardiovascular disease and mortality in individuals with and without type 2 diabetes: A prospective study in the UK Biobank. Diabetes Metab. 2024;50:101554. doi:10.1016/j.diabet.2024.101554

We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.

However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.

Improves diabetes symptoms

Most Useful Review

9 people found this helpful

I purchased this chelate for my mother, as other forms didn't work for her digestive issues. It has calmed her and improved her sleep, and her diabetes-related cramps have vanished.

Gastroesophageal Reflux Disease details

Decreased heartburn attacks

Anyone suffering from Gastroesophageal Reflux Disease should buy this! Magnesium helps regulate the autonomic nervous system, which controls the valve preventing gastric juices from entering the oesophagus. My constant heartburn made it impossible to lie down after meals, but after a few days of taking this magnesium, I noticed a significant reduction in heartburn episodes. I felt confident enough to lie down half an hour post-dinner without any discomfort. It's truly effective!

Atrial Flutter details

Effective magnesium supplement

22 people found this helpful

This magnesium is a must-have as it provides the best relief compared to other types I've tried. Since starting one tablet daily, I've stopped getting migraines, and after my father's atrial flutter diagnosis, his arrhythmia has also ceased since he began taking it. Highly recommended for absorbable magnesium.

Bacterial Infection details

Significant improvement

After taking this magnesium, my ear infection has greatly improved. The packaging is satisfactory and the efficacy is noticeable quickly. I'm truly pleased with the results!

High Cholesterol details

Magnesium chloride reduces liver stress

Based on 9 Researches

Mohammed KA, Goji ADT, Tanko Y, Muhammed A, Salisu IA. Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats. Niger J Physiol Sci. 2019;34:149.

We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.

In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.

We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.

This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.

Relieves inflammation

Most Useful Review

104 people found this helpful

It's best to increase intake from 10 to 20 eggs per day. I noticed unbelievable relief from allergic rhinitis and frequent inflammation after one month of taking a high dose of omega 3.

Acne details

Mesoporous magnesium carbonate fights acne

Welch K, Latifzada MA, Frykstrand S, Strømme M. Investigation of the Antibacterial Effect of Mesoporous Magnesium Carbonate. ACS Omega. 2016;1:907. doi:10.1021/acsomega.6b00124

This study looks into how mesoporous magnesium carbonate (MMC) can help with acne by reducing bacteria that thrive on our skin. We used a specific Gram-positive bacterium considered a common culprit in acne lesions. To ensure our results were reliable, we measured bacterial activity using a metabolic assay.

Our findings revealed that MMC exhibits a strong antibacterial effect against this acne-related bacterium. A significant factor contributing to its effectiveness is the material's alkalinity. This suggests that MMC could be developed further as a skincare ingredient aimed at inhibiting bacterial growth, providing an alternative to traditional antibiotic treatments.

Overall, we see promising potential for MMC in topical applications, especially for those looking for non-antibiotic solutions to manage acne and maintain skin health.

Improves skin and mood

Most Useful Review

Excellent! We combined magnesium with omega, vitamin D3, and B complex. My sleep quality improved, leading to fewer headaches and back pain. My skin condition has enhanced; my acne cleared up, and new spots appeared less frequently.

Allergies details

Magnesium enhances postoperative recovery

Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. doi:10.2147/DDDT.S444896

We conducted a study to see how magnesium sulfate could influence recovery after total knee arthroplasty in older patients. Using a double-blind, randomized control design, 148 patients were split into two groups: one received magnesium sulfate while the other got saline.

We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.

Effective for allergies

Most Useful Review

68 people found this helpful

I've been using this vitamin for over six months and honestly can't live without it. It has greatly helped my allergies, asthma, and fatigue. The energy boost I get is remarkable, and I can't fathom my day without it!

Autoimmune Disorder details

Magnesium shows promise for RA treatment

Based on 10 Researches

Laragione T, Harris C, Gulko PS. Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways. Nutrients. 2024;16. doi:10.3390/nu16234247

We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.

Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.

Significant improvement

Most Useful Review

216 people found this helpful

I tried taking magnesium from local brands with no noticeable changes. After ordering this product, I immediately observed a significant difference. I recommend that everyone gives it a go.

Cardiovascular Disease details

Nielsen FH. The Role of Dietary Magnesium in Cardiovascular Disease. Nutrients. 2024;16. doi:10.3390/nu16234223

Magnesium's impact on heart health

We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.

Effective for numbness

Most Useful Review

200 people found this helpful

Magnesium is one of the most vital minerals in the human body, essential for the nervous, cardiovascular, skeletal, and muscular systems. After my arm went numb at night, I started taking magnesium. Following just one tablet each morning, the numbness disappeared! I'm very pleased and would highly recommend it!

Hashimoto details

I began taking this magnesium due to muscle spasms and long-standing sleep issues. I had read that magnesium helps with both these concerns, especially for those with Hashimoto's. The glycinate form is recommended for those with normal bowel habits or prone to diarrhoea. Now, with at least two capsules daily, my spasms have ceased, and I enjoy solid sleep of 6-8 hours. If I wake, I easily fall back asleep. I am absolutely thrilled! I wish I had started this earlier. Doctor's Best products are excellent.

Osteoporosis details

Magnesium's role in osteoporosis therapy

Based on 19 Researches

Li J, Chen Y, Zha D, Wu C, Li X, et al. Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism. Lipids Health Dis. 2024;23:88. doi:10.1186/s12944-024-02083-3

We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.

Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.

In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.

Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.

Important for elderly

Most Useful Review

2 people found this helpful

Today, we must fully recognise magnesium deficiency's importance, especially among the elderly. Osteoporosis poses a significant issue in this group, as insufficient magnesium intake can lead to increased bone fragility. Adequate magnesium may slow the decline in skeletal muscle mass, thus reducing osteoporosis and the risk of fractures. Thanks for the thumbs up! ❤️❤️

Heart Attack details

Magnesium implantation improves heart recovery

Based on 23 Researches

Wang B, Pan S, Nie C, Zou R, Liu J, et al. Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats. Sci Rep. 2024;14:10959. doi:10.1038/s41598-024-60609-2

We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.

Supports heart function

Most Useful Review

138 people found this helpful

Following a heart attack, magnesium has been very beneficial for my body in maintaining normal cardiovascular function. I now take this supplement regularly to prevent future issues.

Heart Disease details

Magnesium supplements lower heart failure risk

Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. doi:10.1161/JAHA.124.038870

We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.

In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.

Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.

Enhanced relaxation benefits

Most Useful Review

1258 people found this helpful

I've found magnesium, particularly its connection with amino acids, incredibly beneficial. It absorbs well and supports relaxation, sound sleep, and blood pressure normalisation. I alternate my magnesium type every three months based on my needs, feeling rejuvenated with each cycle. It’s become an essential part of my health routine, aiding significantly in managing my heart health.

Sleep Apnea details

Magnesium's role in sleep apnea

Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. doi:10.1016/j.jad.2024.05.002

We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.

Improved sleep quality

Most Useful Review

100 people found this helpful

Excellent magnesium, combined with lysine and glycine for optimal absorption. I take it almost daily, and it normalises my sleep. I fall asleep easily and my nervous system recovers well after a busy day. No adverse effects on my gut.

Swollen Lymph Nodes details

120 people found this helpful

Mind-blowing effect! After 14 days of taking it, my PMS symptoms disappeared—no irritability, chest pain, or swelling. My sleep has improved, and I now have regular bowel movements each morning. My cravings for sweets have decreased. The tablets are tasteless, and I've experienced no side effects. I do recommend it!

Blood Clot details

Magnesium scaffold shows promising results

Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study. EuroIntervention. 2023;19:e414. doi:10.4244/EIJ-D-23-00326

We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.

Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.

Overall, our findings support its potential use in heart treatments.

7.5

Blood clot prevention

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112 people found this helpful

Magnesium reduces the activity of substances that contribute to blood clot formation. It is crucial for maintaining heart health and should be taken by everyone for optimal cardiovascular function.

Blurred Vision details

Eliminated blurred vision

1 people found this helpful

After several months of being advised to try it for the blinking phenomenon, I began taking this supplement. Exactly two weeks later, the symptoms of blurred eyes that had been persistently bothering me disappeared!

Food Poisoning details

Magnesium oxide shows promise against EHEC

Hirakawa H, Suzue K, Uchida M, Takita A, Kamitani W, et al. A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic , Which Attenuates Virulence. Front Microbiol. 2022;13:883689. doi:10.3389/fmicb.2022.883689

We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.

Improved mood

Most Useful Review

24 people found this helpful

Magnesium has been my go-to for seasonal affective disorder and stress relief. I take it daily now, regardless of indications, as it helps with muscle spasms and sleep issues. This chelated magnesium works quickly, with noticeable results within a week. It's made a significant difference in my mental well-being.

Indigestion details

No unpleasant side effects

9 people found this helpful

This magnesium formula is enjoyable. I have heart issues and rely on magnesium and omega Q10. Previous supplements caused unpleasant side effects like indigestion, but with Doctor's Best, no such issues occurred. Overall, I am satisfied with this product.

Headache details

Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725

Magnesium aids migraine management

We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.

7.5

Back pain relieved

Most Useful Review

162 people found this helpful

The magnesium composition is excellent. I take two capsules at night, and on occasion, I add another if I feel stressed or have restless sleep. This routine has stopped my back pain and greatly reduced headaches, allowing me to feel rejuvenated. I find it indispensable for managing stress and overall health.

Reflux details

Magnesium alginate effectively treats LPR

Based on 11 Researches

Ciprandi G, Damiani V, Passali FM, Crisanti A, Motta G, et al. Magnesium alginate in patients with laryngopharyngeal reflux. J Biol Regul Homeost Agents. 2021;35:61. doi:10.23812/21-1supp2-12

We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.

The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.

Reduces burning sensation

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2 people found this helpful

Doctor prescribed antacids for acid reflux, but I opted for a natural remedy. Whenever I feel a burn in my stomach, I take a few of these tablets and find I no longer need antacids. It also aids digestion.

Irritable Bowel Syndrome details

Magnesium boosts colonic activity

Harvey RF, Read AE. Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome. Gut. 1973;14:983.

We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.

Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.

Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.

Effective for constipation

Most Useful Review

9 people found this helpful

I struggled with constipation since childhood. After trying numerous supplements with little success, this one finally provided relief. I've been taking it for nearly three years, and while I adjust my dosage, its effectiveness remains consistent. It has significantly eased my concerns about bowel movements.

Constipation details

Effective treatment for chronic constipation

Based on 22 Researches

Morishita D, Tomita T, Mori S, Kimura T, Oshima T, et al. Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial. Am J Gastroenterol. 2021;116:152. doi:10.14309/ajg.0000000000000942

We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.

Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.

Importantly, there were no severe treatment-related side effects reported during the trial.

7.5

Resolved constipation

Most Useful Review

121 people found this helpful

My life-changing saviour! I’ve spent years in and out of emergency rooms and struggled with many issues, including a decade-long constipation problem. After trying magnesium, I experienced incredible benefits within days. My constipation has almost resolved, and my overall health has improved remarkably. I love this supplement and even shared it with my sisters, who also saw improvements.

Kidney Stones details

Magnesium reduces kidney stone risk

Based on 9 Researches

Taheri M, Jalali S, Borumandnia N, Tavasoli S, Basiri A, et al. Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial. Magnes Res. 2024;37:12. doi:10.1684/mrh.2024.0524

We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.

After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.

Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.

Kidney sand removal

Most Useful Review

1 people found this helpful

One of my favourite magnesiums! I tend to form stones in my kidneys. A year after drinking this brand, my kidney sand has disappeared. I’ll keep taking it!

Common Cold details

22 people found this helpful

Persistent cold feet and cramps plagued me until I took a magnesium supplement, which resolved these issues within just a few days. After consulting a professional about my magnesium levels, I was pleased to find that this product provided the relief I desperately needed at a reasonable price.

Rash details

Magnesium affects rash treatment efficacy

Based on 2 Researches

Neckermann G, Bavandi A, Meingassner JG. Atopic dermatitis-like symptoms in hypomagnesaemic hairless rats are prevented and inhibited by systemic or topical SDZ ASM 981. Br J Dermatol. 2000;142:669.

We investigated how magnesium deficiency affects rash in hairless rats, which develop a severe, itchy rash resembling atopic dermatitis. In our study, we tested a derivative called SDZ ASM 981, given either systemically or topically. Remarkably, oral treatment with SDZ ASM 981 significantly cleared the rash within just one day.

Furthermore, this treatment reduced several inflammatory markers, showing promising results for both prevention and therapy. This indicates that magnesium's role might be crucial in managing similar skin conditions in humans, reinforcing the value of this rat model for effective treatment evaluation.

No skin rash

Most Useful Review

Best magnesium I've had! It significantly reduces muscle cramps without causing any skin rash, unlike cheaper, lower-quality magnesium tablets.

Nausea details

Hua X, Chen Y, Wu Z, Zheng G, Yang D, et al. Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial. Heliyon. 2024;10:e30342. doi:10.1016/j.heliyon.2024.e30342

Based on 4 Researches

Magnesium effectively reduces PONV

We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.

We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.

Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.

This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.

No nausea at all

Most Useful Review

91 people found this helpful

Effective and cost-effective magnesium supplementation. I recognised that my diet lacked enough sources, and this form is easily absorbed, causing no side effects, including nausea. I feel better overall and have noticed improvements in sleep quality since taking this supplement.

Bloating details

Magnesium alleviates menstrual bloating

Walker AF, De Souza MC, Vickers MF, Abeyasekera S, Collins ML, et al. Magnesium supplementation alleviates premenstrual symptoms of fluid retention. J Womens Health. 1998;7:1157.

We explored the impact of magnesium supplementation on bloating as part of a larger study examining premenstrual symptoms. In our randomized, double-blind, placebo-controlled design, we administered a daily dose of 200 mg of magnesium (as MgO) to participants over the course of two menstrual cycles. Each volunteer kept track of their symptoms using a detailed diary with twenty-two items.

Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.

Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.

Reduces bloating

Most Useful Review

8 people found this helpful

I cut it in half with my teeth and drink it! Since I started taking it, my intestines are in great condition. I no longer feel bloated. I take two tablets in the morning and three at night. Initially, swallowing was fine, but it began to stick in my throat, so I tried breaking it in half. It feels good. If you think it's too big, give this a try. If you lack strong teeth, I recommend cutting it first.

Adenoiditis details

Sleep improvement observed

118 people found this helpful

Effective for a good night's sleep! It was helpful in improving my sleep quality. I felt naturally drowsy a few hours after taking it. It’s crucial to choose chelated forms for better absorption; this product is quite good in that regard. I recommend taking 1.5 tablets daily, and I've found that sleep improves significantly with this dosage. I hope my experiences help others!

Diarrhea details