I use these for my 2 dogs. I have a 65 pound 5 year old German Shepherd and a 55 pound 9 year old Golden Retriever. Both dogs are very active and get up and go without any resistance. I give the dogs one each with food in the morning and one each with food in the evening. My dogs have been on this for about 3 months now and the difference is really noticeable. They used to lay around a lot more and now they are more active. My husband has noticed this as well. I was so impressed that me and my husband started taking this glucosamine last week. We have zero side effects and feel good so far. I know it takes time but so far so good. If this review was helpful to you in any way, please let me know by clicking on helpful. Thank you so much!! :

My hip had been bothering me for 6 months and I was starting to limp. What the heck, I'm 75 and wearing out. A friend with whom I fly RC airplanes suggested glucosamine & chondrotin. He told me that his doctor wanted him to think about a knee replacement when he decided to try GC. He told me it had been 7 years and he still has the same knee. I figured it was worth a try. I checked Amazon for prices and recommendations and ended up with Doctor's Best. After less than 2 weeks I noticed that my hip joint wasn't bothering me any more. It wasn't instant, just one day I noticed I wasn't limping. Son of a gun, this stuff works. It sure beats taking a lot of ibuprofin. I highly recommend it for "greasing up" and smoothing out your joints

A year and a half later I confirm again that it works for me like magic. I want to emphasize that I was not asked for this review, nor getting any free product. Here is the story. After finishing the first bottle, for the reason I don't remember, I decided to buy a different brand of glucosamine. It was probably also working for my joints because I didn't experience any pain. But it was making me feel dizzy. I'd stop for a while and start again and every time I felt dizzy. So I stopped it all together. A few months later my knees started hurting again and I remembered my own praise for Doctor's Best glucosamine. Now I am back on track: one capsule a day (maybe it is enough for highly sensitive people?) and the knee pain is gone from the day one. Amazing! I have to mention that when I started Doctor's Best almost two years ago I also experienced dizziness at first (just didn't know it could be related) but it improved within a few days. When I restarted this time, there were no side-effects at all. And you know what? I think it works for my dog too. A few months ago our 9 year-old Yorkie started hesitating and sometimes completely refusing to jump up just a few steps on the stairs. The vet didn't see anything wrong with her joints. We decided to start adding a tiny bit of glucosamine in her food once a day and see if that helps. Within a week she started jumping stairs again without hesitation. Keep in mind that our dog is also on a perfect anti-inflammatory diet: all homemade, mostly organic, no junk food at all. ------ I rarely write reviews for the supplements because it's hard to determine whether this particular supplement is actually working. This time something amazing happened, so I want to share it; maybe it will help someone else. For a few weeks I'd been feeling mild but persistent pain in my both knees that did not allow me to walk stairs freely like I used to. When I bought this Glucosamine Chondroitin MSM I was hoping that within a few weeks of taking it my knees will start feeling better. The unexpected magic happened! I took just one capsule in the evening and I woke up next morning without any discomfort in my knees! I know... can it be really so potent?! Maybe it's just a coincidence but it also could be a synergistic effect and the final piece of the puzzle is in its place. In addition to my diligent anti-inflammatory diet, I take Fish Oil, Turmeric and Boswellia for quite a while now. It seems to be working for me pretty well because most of the time I don't even feel any signs of arthritis that was haunting me many years ago. Now I added Glucosamine Chondroitin MSM and all my joints are happy. I still take just one, sometimes two, capsules a day instead of recommended 4. It works! Try it. Highly recommend

This supplement is the best I have ever purchased because it gave me my life back! I suffered chronic pain for 9 years everyday level 7 to 9. I have Fibromyalgia. The more I used my muscles the longer they would hurt during the rest of the day/night. This made me avoid doing practically everything because the pain was unrelenting, intense and no over the counter NSAIDS, helped. I went to a nuerologist who prescribed me Lyrica and another one specially to treat it and that didn't take away ANY pain and made me so drowsy I fell asleep sitting straight up without my back against the chair even! I could not function on the prescription drugs for my condition. One particuarly bad, pain filled day I was online grasping at straws to find SOME WAY to help with the horrid pain (Doctors won't prescribe pain killers for it, even though they DO work for it) I read fibro blogs on pain relief and they mentioned condroiton and MSM, I bought this brand, started with 1 capsule a day, it took about 2 1/2 weeks, but the pain was lessened! after a month I increased it to 2 pills, 1 in the am one in the PM and now Most days my pain is GONE!!! I am so mad at traditional doctors and neurologists for not even suggesting I try this!! I suffered for YEARS unnecessarily!!!! IMO it is a travesty we aren't told by our Drs that there are safe over the counter supplements that we can buy at a reasonable cost that do BETTER than the prescriptions which alot of have bad side effects and don't even freakin work! THIS works for me! I had tried everything else, accupuncture, massage, water therapy,prescriptions, advil,and tylenol. I highly reccomend this supplement

I recently began a new fitness program that put a pounding on my 50 year old knees. I was so sore that I could hardly walk, but I was making great progress toward my goal but not without pain. I did some research and read several reviews about Glucosamine Chondroitin and MSM. I subscribe to a service that rates supplements that tells you if they work, and then test several brands to see if they have what they say they have in them, and if there is anything in there that should not be. I was very happy to see this brand was highly recommended so I gave them a try. After taking 2 tabs twice a day for the first week, I can tell you that I was able to see a big reduction in my pain, almost totally gone even after continuing and intensifying my workout! I'm a believer in it because I can now exercise the way I want and need too without pain. I highly recommend

If you are new to MSM, you should read THE MIRACLE OF MSM by Stanley Jacob, MD. He explains MSM and how it works in layman's terms. I've dealt with joint pain AND sciatic pain that was so painful I was wondering if I had cancer in both my legs! The following protocol/regimen is what has brought me to a place of being, literally, 99% pain free. It is my opinion (personal experience) that the combination of the hyaluronic acid and collagen II along with Doctor's Best MSM has just about cured me. This is by Russell Blaylock, MD Special Supplements to Repair Joints * *Hyaluronic acid The joint contains cartilage composed of complex glycosaminoglycans, which aid in joint health. One product that supplies this vital substance is hyaluronic acid. This is a component of connective tissue whose function is to cushion and lubricate. Some products contain the larger molecular form, which is not absorbed. Pure Encapsulation Company makes a product under this name. It has a lower molecular weight and is well absorbed. The dose is three capsules twice a day with or between meals. You can get Pure Encapsulation products at [...] * *MSM Also called methyl sulfonyl methane, MSM is a natural form of sulfur found in living organisms. Its main benefits are a reduction of inflammation and the ability to penetrate many tissues, including joints. Recent studies have confirmed its safety, even when used in large doses over prolonged periods of time. The dose is 500 mg. to 1,000 mg. two to three times a day with meals. It is widely available. * *Collagen type II This is a major component in cartilage, and supplementation has demonstrated benefits in reducing pain and improving joint function. The dose is three capsules twice a day on an empty stomach. It is important that you get a brand made from chicken rather than bovine. You can get this from [...] * Tart cherry extract A number of studies have shown that concentrated extracts of tart cherries improve joint function and reduce pain and swelling. You can also get this fromJuly 2006 The Blaylock Wellness Report Page 5 [...]. The dose is one to two capsules a day. * Triple stack This is a special compounded supplement containing full therapeutic doses of MSM, glucosamine, and curcumin. The dose is one capsule three times a day. It should be taken with meals. The best results are seen within three weeks. It can only be found at Specialty Pharmacy [...] Special Supplements to Reduce Inflammation Below I will discuss special plant extracts and vitamins that can reduce inflammation and free radicals within the joint. * *Curcumin This is one of the most powerful natural anti- inflammatory substances known. Its effects are comparable to steroids, without the harmful effects. All inflammatory arthritis problems arise from the activation of a special inflammation signal molecule in cartilage cells called NFkappaB, or NFKB. Curcumin powerfully inhibits this cell signal and also suppresses the destructive enzymes mentioned above (MMPs and collagenase). Curcumin is best absorbed when dissolved in an oil. I would recommend either extra virgin olive oil or fish oil. Fish oil has a significant anti-inflammatory effect all its own, so I would recommend over olive oil. The dose is 250 mg. of curcumin powder mixed with a half-tablespoon of fish oil. Mix well. Take this three times a day with meals. * *Quercetin This is also a powerful anti-inflammatory and antioxidant. When combined with curcumin, you get a powerful anti-inflammatory effect because they each act on different inflammatory biochemical pathways. It also suppresses the destructive enzymes I spoke about (MMPs and collagenase). Mix 250 mg. of quercetin into oil with the curcumin and take that three times a day. * *Borage oil Borage oil contains a high concentration of gamma-linolenic acid, which has significant anti- inflammatory properties. It also moistens mucous membranes and the skin. You can add this to the mix above. It will come in a gelatin capsule, but don't eat that -- just stick a pin into it and squeeze 1,000 mg. into the mentioned mix twice a day. Keep both the fish oil and borage oil in the refrigerator. * *Natural vitamin E (Unique-E) Vitamin E, in natural form, has significant anti- inflammatory effects. The dose is 1,000 IU a day. Unique-E is the brand I recommend. * *Buffered vitamin C (calcium/magnesium ascorbate) Vitamin C is not only a powerful antioxidant and anti-inflammatory, but it also strengthens the tissues and the ligaments surrounding the joint. * *Vitamin/mineral supplement A recent study found that selenium was significantly depleted in the joints of people with arthritis, while copper levels increased. High iron levels were found in the damaged joints of osteoarthritis sufferers. Iron is a powerful generator of inflammation and free radicals. A well-balanced supplement such as Extend Core [...]will deliver all the essential vitamins and minerals. * *Magnesium citrate or citrate/malate Magnesium supplementation has been shown to reduce inflammation, while a deficiency increases it. It not only slashes free radicals but blocks the release of inflammatory cytokines as well. The dose is two capsules twice a day between meals. A survey found that a dearth of magnesium is one of the most common mineral deficiencies seen, with 75% of the population lacking it. Chronic illness and many medications worsen magnesium loss. * Stinging nettle extract This plant extract has been shown to have powerful anti-inflammatory properties. Recent studies have found it to be very protective of the brain as well. It is often included in natural supplements used to treat chronic prostate problems for the same reason. But taking too much can produce a mucous-like diarrhea. I would limit intake to two capsules a day with meals. These are the basic steps you will need to follow for good health. I have placed an asterisk beside the most important supplements. The closer you follow these steps the more likely you will attain success. It is important to know that curcumin and quercetin can cause your blood sugar to drop slightly. While this is beneficial to those with diabetes, it can be a problem if you have reactive hypoglycemia. For this reason, always take it with a meal

I like these, although it's hard to tell how well any supplement works. My joint pain has not come back since I switched to this brand, so I'm giving this my 5 Star rating. Before using Glucosamine/Chondroitin/MSM supplements, I had severe joint pain in my shoulders, and this combination absolutely worked to relieve it! IMHO always look for a 1500/1200/1000 mixture and avoid "proprietary blends" at all cost! Propriatary blends means they don't want you to know how much (or how little) and/or what compounds they put into their crap. I used to get WalM***'s brand but I had a hard time finding it and switched to these. I like these a lot and it has the same blend, but in a capsule instead of a pill, which I find easier to swallow

My doctor recommended that I go and see an Orthopedic Doctor for my worsening knee pain. He prescribed a prescription gel that I was to apply four times a day. Very messy, but I done as he told me for around 2 weeks with no improvement. I went back. They xrayed my knees and told me the joints were worn out. Bone rubbing against bone, with nothing there to cushion the shock. He gave me a shot in each knee. It helped for around a week. I couldn't get any more shots for a month, so I toughed it out. I went back in for more shots. My doctor was gone, I had a new doctor. He gave me the first shot, not too uncomfortable. Time for the second shot, in the worst of my two knees. I have never felt such pain in all my life! Tears were streaming down my cheeks, I had a tight grip of the table I was sitting on. Finally he stopped, pulled the needle out and said "I can't do this to you!" He was so sorry and didn't know what had went wrong. He then sent me for aqua therapy. This helped, while I was moving around in the 96 degree pool. My insurance would not pay for more than 2 months of treatments. It was very expensive to pay out-of-pocket. Plus since I could only go twice a week, my knees hurt just as bad the other 5 days of the week. I went back to see my doctor and he recommended something I had never heard of before. He told me that vets were having amazing success in horses with leg sprains and problems, after they started using this product. I stopped at a pharmacy and bought a bottle of Glucosamine Chondroitin MSM. I buy a lot of vitamins and supplements, most I can never tell if they are working or not. I take 3 capsules per day of these, one in the morning and two at night. I saw results within FOUR DAYS! Then I found these on Amazon. I think they work faster because they are not a solid pill, like I found locally in the pharmacy. I will never, ever run out of these again! It hurt so bad to walk before, with a constant audible crunching of bone rubbing against bone. Now that is mainly gone. These amazing pills put the cushion back, and I LOVE them! UPDATE: I have taken these for months now. My knee pain is gone! There were a few times that I went for a few days, forgetting to take them. I will not make that mistake again! Now when I fill my weekly prescription box, these are included. To me, they are more important than some of the prescriptions that I am taking

I had a car accident 2 years ago that has left me in severe pain from a L5 S1 blown disc that has also been causing hip pain when I walk. After being on Doctor's best, along with same brand Hyaluronic Acid, my pain has diminished by about 90% in 10 days. I wish I had thought to try it sooner. Oddly, my TMJ is also going away. Added benefit. I can't speak for anyone else, but it's absolutely worth every penny for me and I trust this brand to deliver a quality product

I started taking this at age forty in anticipation of hereditary knee problems my father was experiencing. We both have Osgood-Schlatter's disease of the knee. He was due for double knee replacement, but insurance wouldn't cover it. He took this daily and now doesn't need the replacements - even years later. That's incredible anecdotal evidence. After I started taking it, a noticeable ridge appeared in my fingernails where the nails became thicker and the skin on my face looked better. After a third friend commented on how thick my hair looked, I figured out that it must be the MSMGC - a little googling supported the claim that hair, nails, and skin are positively affected