Jarrow Formulas Milk Thistle

Brain Tumor details

Curcumin reduces glioma tumor growth

Based on 9 Researches

Luís Â, Amaral L, Domingues F, Pereira L, Cascalheira JF. Action of Curcumin on Glioblastoma Growth: A Systematic Review with Meta-Analysis of Animal Model Studies. Biomedicines. 2024;12. doi:10.3390/biomedicines12020268

We conducted a thorough investigation into how curcumin, a compound found in turmeric, affects brain tumors, particularly gliomas. Our research involved a systematic review and meta-analysis of 24 studies from 15 different articles. Each study utilized murine xenograft models to observe the effects of curcumin on tumor growth.

Through our analysis, we discovered that curcumin significantly reduced tumor volume compared to control groups. The overall results showed a notable decrease, with a standardized mean difference of -2.079, suggesting a strong therapeutic effect.

We explored various conditions under which curcumin was tested, including different animal models and administration methods. While we did identify some publication bias in the existing studies, this did not negate the effectiveness of curcumin. Overall, our findings strongly advocate for further research into curcumin as a potential treatment for gliomas.

Effective treatment

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103 people found this helpful

I have been taking 2 gms (four capsules) of curcumin daily since my stage 4 breast cancer diagnosis a year ago. Remarkably, I entered remission within three months, and all tumours have disappeared. I have now been in remission with no evidence of disease for eight months.

Updated: Apr 2025

Diabetes details

33 people found this helpful

I've been using milk thistle daily for my medication-induced type II diabetes. It helps regulate my liver's glucose release, particularly after taking pain relievers. Over ten years, I've seen noticeable improvements in my energy and overall health, showcasing its value in managing my condition.

Heart Disease details

Nano-curcumin improves heart health

Rezaei M, Soltani M, Alipoor E, Rezayat SM, Vasheghani-Farahani A, et al. Effect of nano-curcumin supplementation on angina status, and traditional and novel cardiovascular risk factors in overweight or obese patients with coronary slow flow phenomenon: a randomized double-blind placebo-controlled clinical trial. BMC Nutr. 2024;10:73. doi:10.1186/s40795-024-00877-3

We conducted a double-blind, placebo-controlled trial to see how nano-curcumin, a supplement derived from turmeric, affects heart health in overweight or obese patients with a condition known as coronary slow flow phenomenon (CSFP). Our study involved 42 participants who received either 80 mg of nano-curcumin or a placebo daily for 12 weeks.

To measure how angina—a type of chest pain—improved, we used the Seattle angina questionnaire among other cardiovascular risk factors, including endocan, adropin, homocysteine levels, and various lipid profiles.

At the end of the study, we observed that those taking nano-curcumin reported significant improvements in their angina status and some cardiovascular factors, compared to their baseline measures. While some improvements were also seen in traditional and novel risk factors, more research will be needed to understand these changes in depth and whether they offer any real-world benefits for heart health.

Eliminated pain relief

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14 people found this helpful

This is a fantastic product. I use it for its anti-inflammatory properties, which have allowed me to nearly stop using Ibuprofen. My cardiologist considers me his most boring patient after having two heart stents for almost six years. I also take nattokinase and serrapeptase to maintain excellent cardiovascular health.

Updated: Mar 2026

Indigestion details

9 people found this helpful

I have been taking Curcumin 500mg for over a year since my first gallstone attack. Initially, it alleviated the uncomfortable indigestion and restored my pale complexion. I take it twice a day, and over the last six months, I have not observed any signs of gallstones. It's a great product.

Irritable Bowel Syndrome details

Questionable

Turmeric may alleviate IBS symptoms

Bundy R, Walker AF, Middleton RW, Booth J. Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study. J Altern Complement Med. 2004;10:1015.

We undertook an investigation to understand how turmeric, scientifically known as Curcuma longa, might affect symptoms of irritable bowel syndrome (IBS) in healthy adults. In a well-structured pilot study, we screened 500 volunteers for IBS and ultimately randomized 207 suitable candidates to assess the impact of taking one or two tablets of a standardized turmeric extract daily for eight weeks.

Throughout the study, we observed significant improvements in IBS symptoms. The prevalence of IBS symptoms decreased notably in both dosage groups, and after treatment, those taking one tablet saw a 53% reduction in symptoms, while the two-tablet group experienced a 60% decline. We also noted a meaningful reduction in abdominal pain and discomfort, with scores dropping by 22% and 25% respectively.

Furthermore, most participants reported improved overall quality of life related to their IBS symptoms. Approximately two-thirds of individuals noted a positive change in their symptoms post-treatment, indicating a favorable response to turmeric. While there were no significant differences between the two dosage groups, the findings confirm that turmeric may offer a helpful option for managing IBS symptoms.

Given these encouraging results, we believe that further placebo-controlled trials are necessary to validate the effectiveness of turmeric in treating IBS.

Improved bowel condition

Most Useful Review

32 people found this helpful

I recommend everything for Crohn's disease! I've struggled with bowel issues for over 10 years and tried various medications. I discovered curcumin online, impressed by its natural composition, and decided to order it. It has anti-inflammatory and antimicrobial effects and is gentle on my stomach. By the second week, my irritable bowel syndrome symptoms improved, and my overall well-being enhanced. It's essential to maintain the correct diet for those with Crohn's. Best of health!

Updated: Apr 2025

Prostate Cancer details

Curcumin's potential in prostate cancer

Mazaheri-Tehrani S, Rouzbahani S, Heidari-Beni M. The Association Between Anti-Neoplastic Effects of Curcumin and Urogenital Cancers: A Systematic Review. Biomed Res Int. 2024;2024:9347381. doi:10.1155/2024/9347381

We evaluated the anti-cancer effects of turmeric, specifically focusing on how it influences prostate cancer. Our systematic review examined various studies that investigated the relationship between curcumin, a component of turmeric, and the regulation of microRNA expressions linked to prostate cancer.

Among the studies we analyzed, we found that curcumin appears to play a significant role in combating prostate cancer by modulating specific microRNAs. This compound seems to promote tumor suppression by increasing beneficial microRNAs while simultaneously decreasing those associated with cancer progression.

By effectively altering the balance of these molecules, curcumin is thought to inhibit cell proliferation and encourage apoptosis, or programmed cell death, in prostate cancer cells. Overall, the evidence suggests that turmeric may serve as a valuable complementary approach in the fight against prostate cancer.

Stronger antioxidant

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23 people found this helpful

Curcumin is known for its powerful anti-cancer actions and strong antioxidant properties. I prefer the Drs. Best 1000 mg caplets over the Jarrow formula for affordability and take it twice daily.

Updated: Mar 2026

Psoriasis details

Curcumin nanogels show psoriasis promise

Ahmad A, Akhtar J, Ahmad M, Islam A, Khan MI, et al. Curcumin Nanogel Preparations: A Promising Alternative for Psoriasis Treatment. Curr Drug Metab. 2024;25:179. doi:10.2174/0113892002312605240508042634

We explored the potential of curcumin, a natural compound derived from turmeric, as a treatment for psoriasis. Known for its anti-inflammatory properties, curcumin has been used in traditional medicine for centuries and is now being recognized for its role in modern therapeutic approaches. Psoriasis, a chronic skin condition marked by red, scaly patches, can be challenging to manage, making the search for effective treatments crucial.

The study highlighted curcumin's ability to inhibit specific enzymes and proteins that contribute to the inflammation and proliferation of skin cells associated with psoriasis. Interestingly, curcumin is being formulated into nanogels—small, crosslinked hydrogels that enhance the delivery of the compound. This nanogel preparation not only boosts the solubility and stability of curcumin but also increases its bioavailability, meaning we may need lower doses to achieve the desired results.

Ultimately, we found that curcumin nanogels present a promising alternative to traditional psoriasis treatments. They offer a potential pathway to more effective and safer treatment options. However, it's essential to emphasize that more research is necessary to fully understand how well these curcumin nanogels work in humans before they become a standard part of psoriasis care.

Milk Thistle clears psoriasis

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481 people found this helpful

After struggling with tiredness and skin issues like psoriasis, I started taking Milk Thistle. I suspected my liver was affected due to years of pain medication. Within a month of use, my psoriasis cleared, and I’ve gained more energy. I've completely changed my diet by eliminating sugars, which has further improved my skin and overall health. I will keep taking it to maintain these benefits.

Updated: Mar 2026

Rosacea details

Turmeric's potential for rosacea

Vaughn AR, Pourang A, Clark AK, Burney W, Sivamani RK. Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study. J Integr Med. 2019;17:20. doi:10.1016/j.joim.2018.11.004

We conducted a study to understand how turmeric, particularly in combination with other herbal ingredients, affects facial redness, which can be a key symptom of rosacea. This was a carefully designed, double-blind, randomized pilot study with thirty participants who took either a placebo, turmeric alone, or a polyherbal formulation for four weeks.

At the end of the study, we assessed the participants' facial redness using clinical grading and a specialized imaging system. The results were promising; our findings indicated that those taking the polyherbal formulation experienced a noticeable improvement in facial redness compared to the other groups.

Although turmeric showed some benefits, it was the combination with other herbs that appeared to make the most significant impact on reducing redness. This suggests that there might be a potential for further exploration of turmeric and its blends in treating skin issues linked with rosacea, but we can't definitively attribute the benefits solely to turmeric itself.

Overall, the study hints at a positive direction for using herbal treatments for rosacea, but additional research is needed to fully understand each component's role and effectiveness.

Energy boost

Most Useful Review

481 people found this helpful

I’ve suffered from tiredness for years, but after using Jarrow Milk Thistle for a month, it has miraculously cleared my skin's psoriasis and rosacea! I’m feeling much more energised, healthier, and ready to be active. Thank God for Milk Thistle!

Updated: Apr 2025

Abscess details

I have been taking the treatment for a month now. The abscess in my chest has resolved, and I will continue with it.

Autoimmune Disorder details

Curcumin improves rheumatoid arthritis symptoms

Pourhabibi-Zarandi F, Rafraf M, Zayeni H, Asghari-Jafarabadi M, Ebrahimi AA. The efficacy of curcumin supplementation on serum total antioxidant capacity, malondialdehyde, and disease activity in women with rheumatoid arthritis: A randomized, double-blind, placebo-controlled clinical trial. Phytother Res. 2024;38:3552. doi:10.1002/ptr.8225

We conducted a clinical trial to explore how curcumin, a compound found in turmeric, affects women with rheumatoid arthritis (RA). Over the course of eight weeks, 48 participants took either a daily curcumin capsule or a placebo. This double-blind, placebo-controlled design ensured that neither the participants nor the researchers knew who was receiving the actual treatment, which adds credibility to our findings.

At the end of the study, we observed some encouraging results. Women who took curcumin showed a significant increase in their serum total antioxidant capacity (TAC), indicating improved antioxidant levels in their bodies. Additionally, these participants experienced a notable decrease in symptoms like tender and swollen joints, pain intensity, and overall disease activity, as measured by the Disease Activity Score in 28 joints (DAS-28).

While levels of malondialdehyde (MDA)—a marker of oxidative stress—decreased in the curcumin group, the change wasn't significantly different when compared to the placebo group. Overall, our findings support the idea that curcumin can be beneficial for women with RA, particularly in reducing disease activity and enhancing antioxidant levels.

Decreased inflammation

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11 people found this helpful

This is my second order of curcumin, which has significantly reduced inflammation in my husband’s autoimmune disorder, IBD. His calprotectin levels dropped from 480 to 180, while following the AIP diet and taking zinc. Overall, these measures together have effectively decreased inflammation, as evidenced by the reduction in his C-reactive protein from 3 to 0.

Updated: Mar 2026

Cardiovascular Disease details

Curcumin protects heart cells effectively

Based on 8 Researches

Yuan Y, Huang H, Hu T, Zou C, Qiao Y, et al. Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1. Int J Mol Med. 2024;54. doi:10.3892/ijmm.2024.5434

We explored how curcumin, a natural compound found in turmeric, can protect heart cells during events like myocardial ischemia/reperfusion injury (I/RI). This type of injury occurs when blood supply returns to the heart after a period of low oxygen, often leading to additional damage to heart tissue.

Through a series of experiments, we observed that curcumin has significant protective effects on heart cells exposed to anoxic stress. Our findings revealed that curcumin improves cell health by reducing cell death, lowering oxidative stress markers, and increasing the body’s antioxidant defenses. Specifically, we noted an increase in important proteins that help protect heart cells, such as HES1 and glutathione peroxidase 4.

Furthermore, curcumin appears to inhibit processes known to contribute to cell death, such as ferroptosis and excessive autophagy, while also reducing apoptosis, which is a form of programmed cell death. This multifaceted approach showcases curcumin's ability to enhance cell survival and maintain heart function during and after ischemic episodes.

Overall, our study supports the potential of turmeric-derived curcumin as a promising natural treatment for reducing the harmful effects of ischemia/reperfusion injury in cardiovascular disease.

Powerful anti-inflammatory

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47 people found this helpful

Curcumin is a concentrated extract of turmeric root with a strong anti-inflammatory effect, beneficial in various conditions including cardiovascular disease. It reduces inflammatory markers and is an effective COX-2 inhibitor, similar to many modern NSAIDs, providing pain relief in arthritis. A typical effective dosage is 1-1.5 grams daily, and it can be combined with Boswellia. It's important to note that curcumin is contraindicated in cases of gallstones.

Updated: Apr 2025

We embarked on an engaging investigation into how highly bioavailable curcumin, a key component of turmeric, affects common cold symptoms. Our study spanned 12 weeks, involving 99 healthy Japanese adults who were randomly divided into three groups. Two groups received different formulations of curcumin while the third group was given a placebo.

Each participant took four capsules daily, and we measured the cumulative days participants experienced cold symptoms. Interestingly, we discovered that those taking either curcumin formulation reported significantly fewer days with cold symptoms compared to the placebo group.

Additionally, we monitored various immune function markers, inflammatory parameters, and overall safety throughout the study. Notably, we observed no adverse effects from curcumin supplementation, making it a promising option for those looking to mitigate cold symptoms naturally.

Recuperates after illness

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1 people found this helpful

Curcumin assists in recovery from chronic conditions and offers protection against common colds during outbreaks. It has antimicrobial properties and is gentle on the gastrointestinal tract, making it essential, especially for recovery post-covid.

Updated: Mar 2026

Lung Cancer details

Curcumin promotes cancer cell death

Xi Y, Zeng S, Tan X, Deng X. Curcumin inhibits the activity of ubiquitin ligase Smurf2 to promote NLRP3‑dependent pyroptosis in non‑small cell lung cancer cells. Int J Oncol. 2025;66. doi:10.3892/ijo.2025.5727

We explored the impact of curcumin, a natural compound found in turmeric, on non-small cell lung cancer (NSCLC). Our investigation utilized two models: laboratory-based NSCLC cell lines (A549 and NCI-H1299) and a mouse tumor model. By applying curcumin treatment, we aimed to understand how it influences cell growth and induces a specific form of cell death known as pyroptosis.

Our findings revealed that curcumin effectively slowed down the growth of NSCLC cells and triggered pyroptosis. This process is mediated through interactions with a protein called Smurf2, which regulates the ubiquitination of another protein, NLRP3. We observed that when Smurf2 activity was inhibited by curcumin, NLRP3 was stabilized, leading to increased levels of pyroptosis-associated factors.

In the animal study, curcumin treatment also resulted in smaller tumor sizes and decreased expression of Ki67, a marker for cell proliferation. Furthermore, this treatment increased NLRP3 and the factors linked to pyroptosis. Overall, our work illustrates how curcumin may hold therapeutic promise for lung cancer treatment by promoting destruction of cancer cells through pyroptosis.

In remission

Most Useful Review

103 people found this helpful

Elizabeth B: Curcumin is known for its anti-cancer properties. I have been taking 2g (4 capsules) daily since shortly after my stage 4 lung cancer diagnosis a year ago. I went into remission within three months, and all my tumours have since disappeared. I have been in remission with no evidence of disease for eight months now.

Updated: Apr 2025

Urinary Tract Infection details

Curcumin inhibits UTI bacteria

Based on 5 Researches

Packiavathy IA, Priya S, Pandian SK, Ravi AV. Inhibition of biofilm development of uropathogens by curcumin - an anti-quorum sensing agent from Curcuma longa. Food Chem. 2014;148:453. doi:10.1016/j.foodchem.2012.08.002

We examined the potential of curcumin, the active ingredient in turmeric, to combat urinary tract infections (UTIs), which are often caused by bacteria forming biofilms. This study specifically looked at how curcumin could interfere with the quorum sensing (QS) systems of uropathogens like Escherichia coli and Pseudomonas aeruginosa.

Our research found that curcumin effectively inhibited the formation of biofilms by these bacteria and was even able to disrupt existing mature biofilms. Using light and confocal laser scanning microscopy, we observed these effects firsthand.

Additionally, we noted that treatment with curcumin reduced important QS-dependent activities in these bacteria, such as exopolysaccharide and alginate production, as well as their swimming and swarming abilities. Remarkably, curcumin also increased the effectiveness of standard antibiotics against these uropathogens, making it a promising option for enhancing current UTI treatments.

Really good effect

Most Useful Review

I ordered it for my father, and he said it was great! It’s truly effective for treating urinary tract infection and inflammation.

Updated: Apr 2025

Asthma details

Curcumin nanoparticles reduce asthma effects

Based on 11 Researches

Ma Y, Ye S, Sun K, Gu Y. Effect of curcumin nanoparticles on proliferation and migration of mouse airway smooth muscle cells and airway inflammatory infiltration. Front Pharmacol. 2024;15:1344333. doi:10.3389/fphar.2024.1344333

We set out to understand how turmeric, specifically its active component curcumin, can affect asthma-related issues in airway smooth muscle cells. To do this, we leveraged curcumin-loaded nanoparticles (CUR-NPs) which enhance the delivery and effectiveness of curcumin, overcoming its natural hurdles like hydrophobicity and instability.

In our study, we isolated airway smooth muscle cells from mice and subjected them to a process that mimics conditions present during asthma attacks, specifically looking at how these cells proliferate and migrate under the influence of a growth factor called TGF-β1. Our observations revealed that CUR-NPs significantly reduced the excessive cell growth and movement that TGF-β1 induces.

Not only did CUR-NPs appear to regulate curcumin’s release effectively, but they also inhibited key pathways involved in inflammation and remodeling of the airways. We also validated our findings using an asthma model in mice, where CUR-NPs treatment visibly reduced inflammatory markers in lung tissue compared to untreated control groups.

Overall, our research suggests that turmeric, through its nanoparticles form, may hold promise as a therapeutic approach for managing asthma by preventing the excessive growth and migration of airway smooth muscle cells.

Potential asthma aid

Most Useful Review

Curcumin is utilised in creating drugs for chronic inflammatory diseases in the body, including asthma. It may help alleviate pain and enhance joint mobility for those with arthritis.

Updated: Mar 2026

Autism details

Effective neuroinflammation relief

5 people found this helpful

One of the very few effective medications recommended for children with autism to alleviate neuroinflammation. This is the only high-purity curcumin available on iHerb suitable for children with this diagnosis. The anti-inflammatory properties of curcumin protect the brain from degenerative processes. I hope this information is helpful.

Back Pain details

Turmeric-Boswellia improves back pain

Based on 3 Researches

Gupta A, Agarwal A. The effect of turmeric-Boswellia formulation (Rhuleave-K) in posture-related low back soreness and discomfort: A randomized double blinded placebo controlled trial. J Back Musculoskelet Rehabil. 2025. doi:10.1177/10538127241296343

We investigated how a turmeric and Boswellia formulation, known as Rhuleave-K, helps manage low back pain related to poor posture. This study involved 52 participants, equally divided by gender, who had been experiencing discomfort for at least two to three weeks.

Using a randomized, placebo-controlled, and double-blinded approach, we carefully measured the pain intensity at the beginning and again at the end of the 15-day trial. The findings were promising; those taking Rhuleave-K experienced a dramatic reduction in pain—showing a reduction of up to 98.5% by the end of the trial. In comparison, the placebo group reported minimal improvement.

We also noted significant decreases in the Oswestry disability index, indicating that participants not only had less pain but also felt increasingly able to carry out daily activities. Overall, this study supports the idea that Rhuleave-K can be a safe and effective option for those looking to alleviate low back discomfort, specifically due to poor posture.

Significant improvement

Most Useful Review

32 people found this helpful

I have been taking curcumin for six months for back pain and found it effective. Initially, my joints were very painful, and I struggled to walk. After three months, I noticed a significant improvement and could manage my back pain better. Although it’s not a panacea, it has had a positive effect alongside my strict diet.

Updated: Apr 2025

Cancer details

46 people found this helpful

Helped our dog tremendously, my husband began taking it too! We started giving this to our dog diagnosed with MCT (cancer) going through chemotherapy. We were told she may have 6-12 months, yet her liver function has steadily improved. She's still with us after 2.5 years at 11 years old. Her oncologist is amazed by her blood work given her cancer and age.

Constipation details

Curcumin improves IBS-C symptoms

Likely Very Effective

Based on 3 Researches

Tu X, Ren H, Bu S. Therapeutic effects of curcumin on constipation-predominant irritable bowel syndrome is associated with modulating gut microbiota and neurotransmitters. Front Microbiol. 2023;14:1274559. doi:10.3389/fmicb.2023.1274559

We set out to explore the effects of curcumin, a compound found in turmeric, on constipation-predominant irritable bowel syndrome (IBS-C). This condition affects a significant portion of the global population, making it essential to investigate potential treatments.

In our assessment, we compared the effectiveness of curcumin to mosapride, a known treatment, by observing changes in gut microbiota and neurotransmitter levels in rat models of IBS-C. Through analysis, we found that the rats receiving curcumin experienced improved bowel movements, characterized by increased fecal weight and water content compared to those with IBS.

Furthermore, our investigations revealed that curcumin treatment led to a reduction in certain neurotransmitters in the serum of the rats. This suggests that curcumin may not only help regulate gut health but also impact the signals that influence bowel function.

Overall, these findings indicate that curcumin could be a promising natural option for managing IBS-C by modifying gut microbiota and balancing neurotransmitter levels.

Solution found

Most Useful Review

This curcumin is effective. It resolved my constipation issues perfectly.

Updated: Mar 2026

Crohn details

32 people found this helpful

I strongly recommend curcumin for those with Crohn's disease! Having suffered from bowel issues for over a decade and experimented with numerous medications—some effective, others not—I discovered curcumin online. Its natural ingredients intrigued me, and after reading various articles, I decided to give it a try. It boasts anti-inflammatory and antimicrobial properties, plus it doesn't irritate my stomach. Remarkably, by the second week, my bowel movements normalised, and my overall health improved significantly. Remember, adhering to the appropriate diet for Crohn's is crucial. Wishing you all good health!

Herbal remedies show promise for eczema

Eczema details

Khiljee S, Rehman N, Khiljee T, Loebenberg R, Ahmad RS. Formulation and clinical evaluation of topical dosage forms of Indian Penny Wort, walnut and turmeric in eczema. Pak J Pharm Sci. 2015;28:2001.

We conducted a study that explored the effectiveness of topical treatments using herbal ingredients, specifically focusing on Indian pennywort, walnut, and turmeric, for managing eczema. Our research included three different formulations—a micro emulsion, gel, and ointment—derived from these extracts. We treated 360 eczema patients in a controlled clinical trial, comparing the results of our formulations with placebo treatments.

Throughout the study, we observed various clinical signs of eczema, including erythema (redness), oedema (swelling), scaling, itching, and lichenification (thickened skin). Interestingly, while each formulation showed benefits, the micro emulsion was particularly effective in reducing redness and swelling. The gel formulation stood out for relieving itching more effectively, whereas the ointment proved to be the best option for managing scaling and lichenification.

It’s important to note that while turmeric was included in our formulations, we couldn't isolate its specific effect due to its combination with other ingredients. However, the overall results suggest that these herbal treatments could serve as promising alternatives for eczema care.

Eczema cured

Most Useful Review

1 people found this helpful

I was suffering from eczema, but it was cured by taking a combination of curcumin and silymarin complex.

Updated: Mar 2026

Leg Cramps details

This turmeric product has significantly improved my menstrual cramps. I used to struggle with leg cramps, but now they are much easier to manage.

Nausea details

Turmeric aids nausea relief

Based on 2 Researches

Zhang X, Deng J, Tang Y, Guan X, Chen X, et al. Zingiberaceae plants/curcumin consumption and multiple health outcomes: An umbrella review of systematic reviews and meta-analyses of randomized controlled trials in humans. Phytother Res. 2022;36:3080. doi:10.1002/ptr.7500

We delved into the myriad ways that turmeric, particularly in the form of ginger supplements, can help mitigate nausea. Our exploration involved synthesizing the findings from 161 different meta-analyses of randomized controlled trials, which ultimately revealed that turmeric is associated with various health benefits.

Specifically, ginger has shown effectiveness in reducing nausea, especially in pregnant women and those undergoing chemotherapy or surgery. Each of these situations often comes with its own set of challenges, prompting individuals to seek effective relief. The ability of turmeric to alleviate these symptoms highlights its potential as a natural remedy.

While the evidence suggests a favorable impact of turmeric on nausea, we also noted that the study’s context—such as the combination of turmeric with other treatments—might complicate how we view its effectiveness. It’s important to consider that while the data is promising, high-quality research is still needed to further confirm these beneficial associations and dissect turmeric’s impact when used in isolation.

Avoided pregnancy nausea

Most Useful Review

13 people found this helpful

I've used milk thistle for two pregnancies to prevent nausea during the first trimester. I used Jarrow during my current pregnancy and am 11 weeks along with no nausea. It's best to take it a couple of months before conception to help liver overload from hormones.

Updated: Mar 2026

Pelvic Pain details

High-quality turmeric

2 people found this helpful

This vegan turmeric is excellent, even for non-vegans. I've taken it for years. I take one capsule in the morning and another in the evening with food for arthritis pain relief. I learned that it stains, so I pour it into a cup to avoid the mess.

Pneumonia details

Reduced blood pressure

Since contracting pneumonia, my blood pressure has risen, and my examination revealed inflammation in my cells. After consuming curcumin, I noticed a significant anti-inflammatory effect, and my blood pressure has now returned to normal.

Like. Skin rashes disappear. It purifies the blood. I take it frequently.

Rash details

37 people found this helpful

Rheumatoid Arthritis details

Liver enzymes are back to normal! Struggling with elevated liver enzymes and rheumatoid arthritis, I researched milk thistle as a possible remedy. After two months on Jarrow's Formulas Milk Thistle, my enzymes normalised completely, providing me reassurance regarding my health. Highly recommended!

Stroke details

Curcumin aids stroke recovery

Yang X, Xu L, Zhao H, Xie T, Wang J, et al. Curcumin protects against cerebral ischemia-reperfusion injury in rats by attenuating oxidative stress and inflammation: A meta-analysis and mechanism exploration. Nutr Res. 2023;113:14. doi:10.1016/j.nutres.2023.02.009

We explored how curcumin, a compound found in turmeric, may help protect the brain from damage caused by stroke. The study we reviewed involved an in-depth analysis, aggregating data from various experiments on rats that experienced cerebral ischemia-reperfusion injury (CIRI), which mimics the conditions of a stroke.

Our findings indicated that curcumin significantly improved neurological outcomes in these animals. We observed a marked reduction in neurological deficit scores, infarct volumes, and brain water content after curcumin treatment. This suggests that curcumin not only helps the brain recover but might also reduce damage during a stroke.

Additionally, the analysis revealed that curcumin enhances the body’s antioxidant defenses while decreasing harmful inflammatory markers. We found increases in beneficial substances like superoxide dismutase and glutathione, alongside decreases in reactive oxygen species and pro-inflammatory cytokines.

Subgroup analyses hinted that the effectiveness of curcumin could vary based on the dosage used. Overall, our exploration supports the potential of curcumin as a neuroprotective agent in stroke treatment, though further research is needed to solidify its practical applications in stroke therapy.

7.5

Improved bowel regularity

Most Useful Review

4 people found this helpful

It is a fantastic product! I initially purchased this for my husband, as I learned that turmeric may assist stroke patients. Afterward, I began taking it too and found it helps me detox. I have regular bowel movements after every meal, which makes me feel great. It has also benefited my husband, who had constipation issues, becoming more regular up to twice daily.

Updated: Mar 2026

Acne details

Curcumin shows promise for acne

Based on 9 Researches

Liu CH, Huang HY. In vitro anti-propionibacterium activity by curcumin containing vesicle system. Chem Pharm Bull (Tokyo). 2013;61:419.

We investigated the potential of curcumin, a natural compound from turmeric, as an effective treatment for acne caused by Propionibacterium acnes. This bacterium can contribute to the development of inflammatory acne, especially when it grows excessively in hair follicles. Our goal was to create lipid-based vehicles to effectively deliver curcumin and see if it could inhibit the growth of this troublesome bacteria.

Using innovative testing methods, including bioluminescence assays, we evaluated how well our curcumin-infused vehicles performed against P. acnes. Additionally, we studied how much curcumin could accumulate in the skin using specialized diffusion cells and high-tech microscopy. The results were promising: we found that our lipid vehicles could accumulate an impressive amount of curcumin in the skin while significantly reducing the bacteria's growth.

Notably, curcumin showed discernible inhibitory effects at a concentration of just 0.43 µg/mL. Moreover, we confirmed through microscopy that the curcumin effectively formed a reservoir in the skin, enabling longer-lasting effects against acne. Overall, these findings suggest that curcumin-based vehicles, particularly when mixed with lauric acid, could serve as a promising new option for treating acne vulgaris.

Hormonal acne solution

Most Useful Review

314 people found this helpful

I finally found relief for my hormonal acne after trying everything. Reading about milk thistle's effectiveness pushed me to give it a chance, and I'm thrilled with the investment; it truly made a difference!

Updated: Apr 2026

Anemia details

Curcumin reduces iron overload effectively

Saeidnia M, Fazeli P, Erfani M, Nowrouzi-Sohrabi P, Tamaddon G, et al. The Effect of Curcumin on Iron Overload in Patients with Beta-Thalassemia Intermedia. Clin Lab. 2022;68. doi:10.7754/Clin.Lab.2021.210629

We set out to understand how curcumin, a compound found in turmeric, affects people with beta-thalassemia intermedia, particularly focusing on iron overload, a common issue in this condition. Our study was carefully designed as a randomized, controlled, double-blind trial. This means that neither the participants nor the researchers knew who was receiving the curcumin treatment or the placebo, which helps ensure the results are reliable.

We conducted blood tests before and after the treatment to measure various iron-related indicators like serum iron, ferritin, and transferrin levels. To our delight, we observed that participants receiving curcumin showed significant reductions in serum iron and ferritin levels compared to those on placebo. Specifically, serum iron levels decreased with a p-value of less than 0.001, and ferritin levels dropped with a p-value of 0.002. Additionally, transferrin saturation also significantly improved in the group taking curcumin.

Overall, our findings suggest that curcumin can be an effective option for managing iron overload in patients dealing with beta-thalassemia intermedia. This provides hope for new strategies in treating this challenging aspect of the disease.

7.5

Improved condition

Most Useful Review

399 people found this helpful

Curcumin did not cause any side effects and effectively helped with my iron deficiency anaemia and other issues. I noticed a significant improvement in my condition. This polyphenol works at the cellular level.

Updated: Apr 2025

Anxiety details

Curcumin shows promise for anxiety

Based on 10 Researches

Fathi S, Agharloo S, Falahatzadeh M, Bahraminavid S, Homayooni A, et al. Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2024;62:253. doi:10.1016/j.clnesp.2024.05.017

We explored the potential of curcumin, a natural compound found in turmeric, as a treatment for anxiety. Through a thorough analysis of eight randomized controlled trials that included 567 participants, we aimed to determine whether curcumin could effectively alleviate anxiety symptoms.

The results were promising. The analysis indicated a significant improvement in anxiety symptoms among those who took curcumin, with a standardized mean difference of -1.56. This suggests that curcumin may lead to a noticeable reduction in anxiety levels. However, it’s important to note that the studies included were limited in number, and the variety in their designs contributed to considerable variation in outcomes.

While we found indications that curcumin may offer benefits for individuals dealing with anxiety, we also recognize the need for further high-quality research to solidify these findings. Until more comprehensive studies are conducted, it's crucial to approach curcumin as a potential supplementary treatment, rather than a standalone solution for anxiety disorders.

7.5

Supports anxiety relief

Most Useful Review

Research indicates that curcumin may aid in managing oxidative and inflammatory conditions, including anxiety and arthritis. Additionally, it can help with recovery from exercise-induced soreness, benefiting overall performance for active individuals.

Updated: Mar 2026

Chronic Fatigue Syndrome details

Curcumin alleviates fatigue symptoms

Likely Very Effective

Gupta A, Vij G, Sharma S, Tirkey N, Rishi P, et al. Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model. Immunobiology. 2009;214:33. doi:10.1016/j.imbio.2008.04.003

We examined the connection between curcumin, a natural compound found in turmeric, and chronic fatigue syndrome in a mouse model. This model used purified lipopolysaccharide (LPS) and Brucella abortus (BA) antigens to induce symptoms of fatigue.

The study involved a water-immersion stress test conducted for 10 minutes each day over 19 days. Notably, the mice treated with LPS or BA showed increased immobility time and heightened sensitivity to pain, which are markers for fatigue. As expected, these mice also exhibited elevated levels of tumor necrosis factor-alpha (TNF-alpha), a sign of inflammation.

Upon administering curcumin during this period, we observed significant improvements. The treatment reduced both the immobility time and pain sensitivity in the mice. Additionally, curcumin helped to lower oxidative stress and the levels of TNF-alpha.

These findings suggest that curcumin could be a promising option for addressing chronic fatigue syndrome, especially related to inflammation and oxidative stress. As we continue to explore this natural remedy, we may uncover more about its potential role in managing this challenging condition.

7.5

Aids fatigue recovery

Most Useful Review

Curcumin is excellent for recovering from fatigue. I often feel tired after workouts, but combining it with ashwagandha has helped me manage my chronic fatigue syndrome effectively.

Updated: Mar 2026

Fibromyalgia details

My wife suffers from fibromyalgia and chronic knee pain. After taking this alongside boswellia extract twice daily, she felt relief after about two weeks.

Gout details

Curcumin nanoparticles effectively combat gout

Based on 6 Researches

Javed C, Noreen R, Niazi SG, Kiyani MM, Ul Ain Q. Anti-gouty arthritis and anti-inflammatory effects of curcumin nanoparticles in monosodium urate crystals induced Balb/C mice. Inflammopharmacology. 2024;32:1929. doi:10.1007/s10787-024-01450-x

We explored the potential of curcumin nanoparticles (CNPs) as a treatment for gout, a condition caused by the buildup of urate crystals in the joints. To investigate this, researchers induced gout-like symptoms in mice by injecting monosodium urate crystals. This led to joint swelling and increased levels of uric acid in the bloodstream.

The study involved administering various concentrations of CNPs, alongside a commonly used medication, allopurinol. The results were promising, showing that CNPs not only lowered uric acid levels and reduced swelling but also decreased inflammation in the affected mice. Interestingly, the application of CNPs increased beneficial substances like high-density lipoprotein and interleukin-10, further supporting their potential health benefits.

Overall, our findings indicate that curcumin nanoparticles present a viable and effective anti-gout treatment with minimal side effects compared to traditional pharmaceuticals. This opens exciting possibilities for developing natural therapies to manage gout and improve patient quality of life.

7.5

Helps with gout

Most Useful Review

I bought this for my dad, who suffers from gout, and it has been helpful for him!

Updated: Mar 2026

Headache details

Curcumin improves migraine symptoms

Based on 8 Researches

Rezaie S, Askari G, Khorvash F, Tarrahi MJ, Amani R. Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial. Int J Prev Med. 2021;12:161. doi:10.4103/ijpvm.IJPVM_405_20

We conducted a thoughtful investigation into the effects of curcumin, a natural compound found in turmeric, on migraine sufferers. This study involved 44 women with migraines, who were randomly assigned to receive either 500 mg of curcumin twice a day or a placebo for eight weeks. The team measured various factors, including the severity, duration, and frequency of headaches, as well as specific inflammation markers in the body.

After the eight-week period, we observed noticeable improvements in the group receiving curcumin. Compared to the placebo, participants taking curcumin reported significant reductions in pain severity and headache duration. While there was a slight improvement in how often headaches struck, it didn't reach a level of statistical significance.

Moreover, curcumin supplementation also appeared to lower levels of two important inflammatory markers related to migraines: calcitonin gene-related peptide (CGRP) and interleukin-6 (IL-6). We didn't see any significant changes in body weight or composition between the groups, indicating that the effects were primarily linked to curcumin's properties rather than any other lifestyle changes.

Overall, our findings suggest that curcumin may serve as an effective, natural remedy for managing migraine symptoms, largely due to its anti-inflammatory benefits.

Relieves detox headaches

Most Useful Review

6 people found this helpful

This product effectively alleviates my detox headaches. I found that other supplements caused mild headaches, but this one does not have any side effects.

Updated: Apr 2026

Heart Attack details

Curcumin shows promise for heart health

Zeng YF, Guo QH, Wei XY, Chen SY, Deng S, et al. Cardioprotective effect of curcumin on myocardial ischemia/reperfusion injury: a meta-analysis of preclinical animal studies. Front Pharmacol. 2023;14:1184292. doi:10.3389/fphar.2023.1184292

We explored how curcumin, a natural compound found in turmeric, might help protect the heart during episodes of myocardial ischemia/reperfusion (I/R) injury. In a comprehensive analysis of 37 animal studies, we looked at the effects of curcumin on heart damage caused by interrupted blood flow, which is a common issue during heart attacks.

Our findings showed that curcumin seemed to have a significant positive impact on reducing the size of heart damage, improving heart function, and lowering harmful enzymes and oxidative stress in the heart muscle. We noted that these effects were consistent across various animal models and dosages used in the studies we reviewed. However, we also discovered some indications of publication bias in the reporting of certain results, which is something to consider in interpreting the data.

While the evidence from animal studies is promising, we must be cautious. It's essential to validate these findings through research in larger animal models and, ultimately, in human clinical trials before we can confidently recommend curcumin as a treatment for heart attack injuries.

Supports heart health

Most Useful Review

1 people found this helpful

This is an excellent product. I take this curcumin twice daily with meals. It’s great for heart health, reduces cholesterol, combats cancer cells, and is anti-inflammatory.

Updated: Apr 2025

Hypertension details

Turmeric supports blood pressure management

Based on 8 Researches

Dehzad MJ, Ghalandari H, Askarpour M. Curcumin/turmeric supplementation could improve blood pressure and endothelial function: A grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2024;59:194. doi:10.1016/j.clnesp.2023.12.009

We explored the potential benefits of turmeric, particularly curcumin, in managing hypertension through a systematic review and meta-analysis of randomized controlled trials. This rigorous examination pulled together findings from several studies to better understand how turmeric could influence blood pressure and related heart health factors.

Our focus was on key indicators such as systolic and diastolic blood pressure, flow-mediated vasodilation, and the levels of certain adhesion molecules that could predict vascular health. By using various reputable online databases, we gathered a wide range of data to offer a comprehensive view of turmeric's effectiveness.

The findings suggest that turmeric supplementation could indeed play a supportive role in improving blood pressure and endothelial function. However, it's essential to note that more research is required to fully understand its impact on inflammatory adhesion molecules in the bloodstream.

Significant improvement

Most Useful Review

I bought this for my father, who has type 2 diabetes mellitus and hypertension. After two weeks of taking it, he reported feeling much better.

Updated: Mar 2026

Knee Pain details

Turmeric shows promise for knee pain

Based on 19 Researches

Dai W, Yan W, Leng X, Chen J, Hu X, et al. Effectiveness of Curcuma longa extract versus placebo for the treatment of knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2021;35:5921. doi:10.1002/ptr.7204

We sought to determine the effectiveness of Curcuma longa extract, commonly known as turmeric, in alleviating knee pain associated with osteoarthritis. Our investigation focused on randomized controlled trials that compared turmeric extract with placebo, analyzing data from notable databases like PubMed and Cochrane Library through April 2021.

In total, we reviewed 10 trials encompassing 783 patients. The outcomes of our analysis were quite promising. We found that patients taking Curcuma longa experienced significantly greater relief from pain and improved overall function compared to those given a placebo. Notably, the measures used to assess pain and functionality showed results that exceeded the minimum clinically important differences, meaning that the improvements were not just statistically significant but also meaningful in real life.

This evidence suggests that incorporating turmeric extract into treatment plans may offer substantial benefits for those suffering from knee osteoarthritis. However, we must acknowledge that the studies we reviewed exhibited some variability, indicating a need for further high-quality research with larger participant groups to corroborate our findings on turmeric’s effectiveness.

Knee support

Most Useful Review

1 people found this helpful

Taking this drug with RSP Nutrition's Joint Support has significantly alleviated my knee pain without side effects. I'm very satisfied with the results.

Updated: Apr 2026

Liver Disease details

Turmeric shows promise for NAFLD

Ashraf A, Rather SA, Mehraj M. "Evaluation of Curcuma zedoaria Rosc. in the management of non-alcoholic fatty liver Disease: A Randomized, single blind, controlled trial". Arab J Gastroenterol. 2025;26:112. doi:10.1016/j.ajg.2025.01.004

In a recent clinical trial, we explored the effectiveness of Curcuma zedoaria Rosc., commonly known as turmeric, in treating non-alcoholic fatty liver disease (NAFLD). This condition is alarmingly widespread, affecting a significant portion of the global population. Over the course of 60 days, we compared turmeric with vitamin E, a standard treatment, to see which had better results.

Our study involved 68 patients with mild to moderate NAFLD, who were divided into two groups. One group received turmeric in capsule form, while the other took vitamin E. We looked at various outcomes, including improvements in liver function, symptoms like digestive issues and malaise, and ultrasound assessments of liver size.

The findings were compelling. We observed that turmeric outperformed vitamin E in alleviating subjective symptoms, such as discomfort in the upper right abdomen, and issues with appetite and digestion. Notably, there were no significant adverse effects reported with turmeric, making it a promising alternative for managing NAFLD.

Overall, our research highlights turmeric as a viable option for those seeking treatment for liver disease, offering benefits that may surpass those of conventional therapies.

Supports liver detox

Most Useful Review

482 people found this helpful

I began detoxifying due to noticeable changes in my skin colour indicating potential liver issues. The product helped improve my liver function significantly, especially when combined with lifestyle changes including a strict diet and hydration. I’m working towards cleansing my liver and have seen improvements in my overall health.

Updated: Mar 2026

Premenstrual Syndrome details

Alleviates PMS symptoms

14 people found this helpful

Elixir of Women's Health! It possesses anti-inflammatory and antibacterial properties, combats irritation and skin redness, rejuvenates and tightens the face, and smoothes wrinkles. It aids in stabilising weight, alleviates premenstrual syndrome symptoms, and addresses menstrual irregularities. This spice also boasts neuroprotective properties, stimulates the brain, enhances memory, and assists in combating depression.

Sleep Apnea details

Curcumin protects neurons in sleep apnea

Based on 3 Researches

He Y, Zhao Y, Lv RJ, Dong N, Wang X, et al. Curcumin triggers the Wnt/β-catenin pathway and shields neurons from injury caused by intermittent hypoxia. Tissue Cell. 2024;91:102587. doi:10.1016/j.tice.2024.102587

We investigated how Curcumin, a compound found in turmeric, may help reduce neuronal damage linked to obstructive sleep apnea (OSA). Using a cell model that simulates intermittent hypoxia, we assessed various factors such as cell health, toxicity, apoptosis (cell death), and the activity of a specific signaling pathway known as Wnt/β-catenin.

Our findings revealed that intermittent hypoxia increases cell death and harmful toxicity while suppressing cell growth and the Wnt/β-catenin pathway. However, when we introduced Curcumin, we noted significant improvements. Cell viability rose, apoptosis rates fell, and cell proliferation was promoted. Additionally, Curcumin helped activate the Wnt/β-catenin pathway, which is crucial for cell survival and function.

To further test our results, we created an animal model of intermittent hypoxia. In this model, Curcumin treatment managed to reduce damage to the hippocampus and restore Wnt/β-catenin pathway activity, validating our cell-based findings. Overall, these promising results suggest that Curcumin might be an innovative approach to battling neurological impairments caused by sleep apnea.

Joint pain relief

Most Useful Review

I took it to my father, who has arthritis. I read that curcumin is a good anti-inflammatory for such a diagnosis. After a few days of taking it, the pain diminished, and I began to sleep normally. I ordered it alongside other vitamins, so we shall see what happens next, but at present, we notice an improvement, as his joints hurt less.

Updated: Mar 2026

Adenoiditis details

Excellent! Following the doctor's prescription, I ordered curcumin. It aids recovery from a severe sore throat, ringworm, and colds, and is particularly beneficial for prevention. I've also read it helps relieve inflammation in arthritis.

Arthritis details

Curcumin reduces osteoarthritis severity

Ding D, Liu G, Yan J, Zhang Q, Meng F, et al. Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway. PLoS One. 2024;19:e0309807. doi:10.1371/journal.pone.0309807

We investigated how curcumin, the active compound in turmeric, impacts osteoarthritis (OA) by focusing on its role in reducing the formation of bone-destroying cells called osteoclasts. In our research, we used a mouse model designed to mimic OA by destabilizing the medial meniscus, allowing us to measure the effects of curcumin on joint health.

Our study included three groups of male mice: those who received a vehicle treatment after their surgery, those with OA but also receiving the vehicle, and those with OA that were treated with curcumin. Over the course of eight weeks, we monitored the mice's cartilage and bone structure, looking for any changes.

We found that curcumin significantly suppressed osteoclast formation and bone resorption without harming the cells, suggesting it may be a promising treatment to alleviate arthritis symptoms. Specifically, curcumin inhibited the activation of important signaling pathways that promote osteoclast formation and cartilage degradation. This suggests a new and exciting approach for treating osteoarthritis, offering hope for better management of this chronic condition.

Effective anti-inflammatory

Most Useful Review

5 people found this helpful

This curcumin product has been fantastic for reducing arthritis inflammation. I started using it after it was featured on a health show, and it has provided me with far superior results compared to alternatives available in Australia.

Updated: Mar 2026

Cold Sores details

Curcumin and blue light therapy

Likely Very Effective

Khalil M, Hamadah O. Photodynamic Therapy Mediated by Curcumin and Blue Light for Recurrent Herpes Labialis: A Case Report. Clin Case Rep. 2025;13:e70160. doi:10.1002/ccr3.70160

We explored the effectiveness of photodynamic therapy (PDT) using curcumin and blue light for treating recurrent cold sores, specifically herpes labialis. This innovative treatment approach was assessed based on its ability to accelerate the healing of lesions and reduce their recurrence.

Our findings suggest that PDT shows promise as a safe and cost-effective option for managing this troublesome condition. However, it is important to note that the study was primarily focused on the combined effect of curcumin with PDT, making it difficult to determine the isolated benefits of curcumin on its own for cold sore treatment.

Overall, our research highlights an exciting potential pathway for alleviating the symptoms associated with recurring herpes labialis, paving the way for future studies to further investigate its components and their individual effects.

Treats cold sores

Most Useful Review

27 people found this helpful

Curcumin is essential if you suffer from pain or inflammation. It's proven to be as effective as ibuprofen for symptoms like joint pain, headaches, and possibly even anxiety linked to inflammation. I double the dose when I sense a flu or cold approaching, which helps me recover quicker.

Updated: Apr 2025

Frozen Shoulder details

Eased shoulder inflammation

Great help with my severe frozen shoulder. I took three pills, three times a day for three weeks. Delivery to Israel took just three days. Excellent service from iHerb!!

Hepatitis details

Turmeric curcumin inhibits HCV entry

Based on 15 Researches

Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, et al. Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. 2014;63:1137.

We investigated turmeric curcumin's ability to block hepatitis C virus (HCV) from entering liver cells. Our study revealed that curcumin effectively inhibits virus entry across all major HCV genotypes without altering viral replication or release.

Through various experiments, we found that curcumin impacts the virus's ability to bind and fuse, thanks to changes in the membrane's fluidity. This suggests that turmeric could be an affordable option for preventing re-infection in patients, particularly those who have undergone liver transplants.

Effective hepatitis treatment

Most Useful Review

28 people found this helpful

After covid, my husband's liver was severely affected (the tests were akin to hepatitis). He took SAMe (Heptral from the pharmacy) and this curcumin for three weeks. Together, these two treatments yielded excellent test results. We chose this specific curcumin because it’s very well absorbed and deemed most effective by our nutritionist. I believe we will continue taking curcumin for prevention. I will certainly reorder this.

Updated: Mar 2026

Obesity details

Turmeric nanovesicles aid obesity treatment

Based on 15 Researches

Wang J, Zhang T, Gu R, Ke Y, Zhang S, et al. Development and Evaluation of Reconstructed Nanovesicles from Turmeric for Multifaceted Obesity Intervention. ACS Nano. 2024;18:23117. doi:10.1021/acsnano.4c05309

We explored the potential of turmeric in challenging obesity, driven by its natural properties and numerous health benefits. Our focus was on a newly developed formulation called "Reconstructed Turmeric-derived Nanovesicles" (Rec-tNVs), which aimed to enhance the effects of curcumin, the active component of turmeric.

By using advanced techniques, we increased the curcumin content significantly in these nanovesicles, allowing us to measure their impact more effectively. The Rec-tNVs showed a remarkable capacity to promote fat breakdown and prevent fat creation in fat cells, while also encouraging the conversion of fat cells to a more metabolically active form.

In rigorous tests involving high-fat diet mouse models, we observed weight reductions of about 18.68% and 14.56% with intragastric and subcutaneous delivery of the Rec-tNVs, respectively, over four weeks. Importantly, these results were better than what we saw with free curcumin treatment alone, suggesting that these nanovesicles could target fat tissues effectively and influence overall metabolism and gut health.

This study highlights the multi-dimensional benefits of turmeric and opens doors for new plant-based treatments for obesity. It's an exciting step forward in the quest for safer weight management solutions.

7.5

Reduces inflammation

Most Useful Review

1 people found this helpful

The benefit of curcumin is its ability to reduce chronic inflammation, which can lead to metabolic disorders, including obesity. It also positively affects arthritis patients by alleviating joint swelling. Regular use of curcumin notably decreases the risk of liver diseases and mitigates symptoms of conditions like hepatitis, diabetes, and periodontitis.

Updated: Apr 2025

Breast Cancer details

Curcumin reduces breast cancer aggressiveness

Li M, Chen L, Wang M, Huang X, Ke Q, et al. Curcumin alleviates the aggressiveness of breast cancer through inhibiting cell adhesion mediated by TEAD4-fibronectin axis. Biochem Pharmacol. 2025;232:116690. doi:10.1016/j.bcp.2024.116690

We explored how curcumin, a compound found in turmeric, can influence breast cancer by targeting specific cellular pathways. The study focused on understanding the role of TEAD4, a transcription factor known to affect cancer cells’ abilities to adhere and invade other tissues.

Our findings revealed that curcumin significantly decreased the migration and invasion capabilities of breast cancer cells. This was particularly important since these qualities contribute to tumor metastasis, which is the leading cause of death in breast cancer patients. In experiments with mice, curcumin also showed the potential to inhibit lung metastasis of breast cancer.

We discovered that TEAD4 promotes the expression of fibronectin, an important protein that helps cancer cells stick to each other and spread. Curcumin was found to disrupt the interaction between TEAD4 and the fibronectin gene, limiting its ability to encourage tumor spread. Interestingly, removing fibronectin from the cancer cells reversed the aggressive behavior induced by TEAD4 overexpression.

Overall, our investigation suggests that the TEAD4-fibronectin pathway could be targeted in breast cancer therapies. Curcumin demonstrates promise in reducing the aggressive nature of breast cancer and could pave the way for new treatment strategies.

Remission achieved

Most Useful Review

103 people found this helpful

I have been taking 2 grams (4 capsules) of curcumin daily since my stage 4 breast cancer diagnosis a year ago. Remarkably, I went into remission within three months, and all tumours have disappeared. I’ve been in remission for eight months with no evidence of disease.

Updated: Apr 2025

Endometriosis details

A very useful supplement! Thanks to the powerful antioxidants in turmeric, it effectively reduces inflammation, cholesterol, and antibodies. It works well for endometriosis. If my review was helpful, please post YES. All health!!!

High Cholesterol details

Turmeric improves cholesterol levels

Dehzad MJ, Ghalandari H, Amini MR, Askarpour M. Effects of curcumin/turmeric supplementation on lipid profile: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Complement Ther Med. 2023;75:102955. doi:10.1016/j.ctim.2023.102955

We aimed to understand how turmeric, specifically its active compound curcumin, affects cholesterol levels in the body. After searching several online databases and analyzing 64 randomized clinical trials, we found that turmeric supplementation can lead to noticeable improvements in key cholesterol metrics.

Specifically, we observed significant reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol (often referred to as "bad" cholesterol). Additionally, there was an increase in high-density lipoprotein cholesterol, known as "good" cholesterol. However, it's important to note that turmeric did not show considerable effects on related apolipoproteins, which are proteins that help carry cholesterol in the blood.

Although these results are promising, we must approach them with caution. The quality of evidence was assessed to be low and very low regarding these outcomes. This means that while turmeric supplementation does seem to help with certain cholesterol levels, more rigorous studies are needed to confirm these benefits and properly evaluate the overall efficacy.

Lowers bad cholesterol

Most Useful Review

2 people found this helpful

Curcumin superbly lowers bad cholesterol levels and reduces blood clot formation. It also blocks inflammatory substances and helps manage atherosclerosis.

Updated: Mar 2026

Migraine details

Nano-curcumin reduces IL-17 levels

Djalali M, Abdolahi M, Hosseini R, Miraghajani M, Mohammadi H, et al. The effects of nano-curcumin supplementation on Th1/Th17 balance in migraine patients: A randomized controlled clinical trial. Complement Ther Clin Pract. 2020;41:101256. doi:10.1016/j.ctcp.2020.101256

We conducted a study to explore how nano-curcumin, a special formulation of turmeric, influences the balance of immune proteins associated with migraines. By randomly assigning forty participants with episodic migraines to receive either an 80 mg dose of nano-curcumin or a placebo for two months, we ensured that our findings would be robust and reliable.

Our primary focus was on two key proteins: interferon gamma (IFN-γ) and interleukin-17 (IL-17). These proteins play significant roles in immune responses and are implicated in migraine pathophysiology. Using advanced techniques like real-time PCR and ELISA, we measured the levels of these proteins in our participants' blood.

The results were promising; we noted a significant decrease in the levels and gene expression of IL-17 in the group taking nano-curcumin compared to the placebo group. However, it’s important to mention that we found no significant differences in the levels of IFN-γ between the groups.

Overall, our findings suggest that nano-curcumin supplementation may provide beneficial effects for migraine patients by specifically targeting IL-17, which could lead to new approaches for managing migraine symptoms going forward.

7.5

Migraine relief

Most Useful Review

Curcumin is the active compound in turmeric, known for its strong anti-inflammatory and antioxidant properties. I have found it helpful in alleviating migraine headaches and easing osteoarthritis. The capsules come well-packaged.

Updated: Mar 2026

Mild Cognitive Impairment details

Excellent for dementia

It is an exceptional nutrient for preventing dementia, acting as an antioxidant and an anti-inflammatory agent.

Gallbladder health improved

Cholecystitis details

Curcumin 95 helped me maintain my gallbladder, which had been filled with impurities. Now, it’s clean. Additionally, it provides various benefits such as reducing inflammation and maintaining brain function.

16 people found this helpful

Cold details

Great! Feel free to take it; the worker does everything perfectly. It prevents illness, as my cold sore vanished completely within three days. In such instances, I take one capsule in the morning and evening or at lunchtime with food. Usually, just one capsule in the morning suffices, taken with food.

Flu details

Supports energy levels

28 people found this helpful

Effective milk thistle, that has helped us both. I purchased this for my wife's liver enzymes, and after a few months, her levels improved, and she also lost weight. My own levels, previously not as high, are now perfect. We check if our pill bottles are sealed tight, and this one was very secure. The capsules are a light yellow and medium-sized, making them easy to take. Our doctor recommended gluten-free milk thistle, and we started three months ago. We also take it when we feel worn down, which seems to help with energy, especially when fighting off a cold or the flu. We’ve tried other brands, but this one is the best and effective. We recommend it to anyone wanting to maintain liver health. Thank you for your attention to our review.

Chest Pain details

Effective for swelling

12 people found this helpful

Very effective for my swelling. I have rheumatoid arthritis, and this product really helps with the pain and swelling; however, please drink plenty of water as it can cause mild constipation.

Allergies details

Curcumin shows no allergy test effects

Based on 10 Researches

Gross LM, Nelson HS, Khatiwada A, Hoyte FCL. Curcumin does not significantly affect immediate skin tests. Allergy Asthma Proc. 2022;43:543. doi:10.2500/aap.2022.43.220067

We focused on how turmeric, specifically curcumin, might influence allergies. Our study involved 34 participants who were allergic to certain antigens. To assess the effect of curcumin, we randomly assigned participants to receive either curcumin or a placebo for one week, all while keeping the study double-blind to eliminate bias.

After this week, we conducted skin-prick tests to measure reactions before and after the treatment. We compared the size of the skin test reactions, or wheals and flares, to see if there were any significant changes.

The results were clear: curcumin did not show a statistically significant impact on the size of these reactions. Although earlier studies suggested that curcumin may help reduce allergic symptoms, our findings indicate that it does not change the immediate response measured through skin tests. Thus, there's no need to stop using curcumin before allergy testing since it doesn't interfere with the results.

No improvement

Most Useful Review

I have allergies and rosacea, so I hoped this would enhance my skin, but it didn't have any effect.

Updated: Mar 2026

Bacterial Infection details

An excellent natural anti-inflammatory agent. It affects me gently. In the initial period of illness, I triple the recommended dose and the "cold" disappears. The key is to catch the onset of the infection or inflammation. A fantastic remedy.

Swollen Lymph Nodes details

Effective for swelling

12 people found this helpful

Very effective on my swelling. I have rheumatoid arthritis and this product really helps with the pain and swelling; however, drink plenty of water as it can cause mild constipation.

Blood Clot details

Curcumin inhibits platelet activation

Based on 7 Researches

Rustichelli S, Lanni C, Zarà M, Guidetti GF, Torti M, et al. Curcumin Modulates Platelet Activation and ROS Production Induced by Amyloid Peptides: New Perspectives in Attenuating Prothrombotic Risk in Alzheimer's Disease Patients. Nutrients. 2024;16. doi:10.3390/nu16244419

We explored how curcumin, a natural compound found in turmeric, affects platelet activation specifically when stimulated by amyloid peptides associated with Alzheimer’s disease. The research aimed to determine if curcumin could help modulate these potentially harmful blood clotting responses.

Using isolated human platelets, we assessed how curcumin influences platelet aggregation and the production of reactive oxygen species. Our findings revealed that curcumin successfully suppressed platelet aggregation triggered by amyloid peptides. This suppression was linked to a decrease in critical signaling pathways involved in platelet activation.

Interestingly, while curcumin significantly inhibited responses to amyloid peptides, its effects on platelet activation induced by standard physiological triggers like thrombin and convulxin were less pronounced. Granule secretion, another aspect of platelet activation, was completely suppressed by curcumin only in response to the hemostatic stimuli, not in the presence of amyloid peptides.

Overall, it seems that curcumin may offer a targeted approach to mitigate the risk of blood clot formation in individuals suffering from Alzheimer’s disease, particularly concerning the pathological roles of amyloid peptides.

Blood composition normalisation

Most Useful Review

Curcumin has the strongest anti-inflammatory effect. It decreases cravings for sweets and fats, lowers bad cholesterol (LDL), and normalises blood composition. Additionally, it improves blood circulation, stimulates red blood cell formation, and reduces platelet aggregation, relieving brain stress and acting as a natural antibiotic.

Updated: Mar 2026

Diarrhea details