Last update
4/12/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
7
We investigated turmeric curcumin's ability to block hepatitis C virus (HCV) from entering liver cells. Our study revealed that curcumin effectively inhibits virus entry across all major HCV genotypes without altering viral replication or release.
Through various experiments, we found that curcumin impacts the virus's ability to bind and fuse, thanks to changes in the membrane's fluidity. This suggests that turmeric could be an affordable option for preventing re-infection in patients, particularly those who have undergone liver transplants.
Through various experiments, we found that curcumin impacts the virus's ability to bind and fuse, thanks to changes in the membrane's fluidity. This suggests that turmeric could be an affordable option for preventing re-infection in patients, particularly those who have undergone liver transplants.
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9
We explored how turmeric curcumin can influence liver health, specifically focusing on its effect on Ca(2+) levels in rat liver cells. The study showed that curcumin blocks the activation of TRPM2 channels, which are linked to liver damage from oxidative stress. When we introduced 5µM of curcumin, it effectively prevented increases in harmful calcium levels caused by substances like hydrogen peroxide and paracetamol. These results support curcumin's role as a hepatoprotective agent, highlighting its potential in treating liver disorders related to oxidative stress.
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9
We explored how curcumin can protect against liver damage caused by paracetamol overdose in male Wistar rats. The study involved four groups, including those receiving curcumin, paracetamol, and a combination of both. Our findings revealed that curcumin significantly improved liver health by restoring antioxidant activity and reducing harmful inflammation compared to the paracetamol-only group. This research highlights curcumin's potential as a protective agent against liver toxicity, although further studies are needed to clarify its exact mechanism of action.
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Most Useful Reviews
9
Effective hepatitis treatment
28 people found this helpful
After covid, my husband's liver was severely affected (the tests were akin to hepatitis). He took SAMe (Heptral from the pharmacy) and this curcumin for three weeks. Together, these two treatments yielded excellent test results. We chose this specific curcumin because it’s very well absorbed and deemed most effective by our nutritionist. I believe we will continue taking curcumin for prevention. I will certainly reorder this.
Read More
9
Normal liver values
9 people found this helpful
Post-Hepatitis A liver values are normal. I've taken silymarin, or milk thistle, before while recovering from Hepatitis A. My liver tests were back to normal three months later, and I am grateful for this product. Now, I'm taking it for post-infectious syndrome and feel significantly better.
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7.5
Positive outcome reported
352 people found this helpful
Can be helpful for liver disease. I have used this product for over three years since my diagnosis of medication-induced liver damage. Initially, my GI specialist only hoped to halt progress after following strict dietary guidelines. However, I noticed positive changes, including normal scans and blood work, confirming my liver's improvement after making various lifestyle changes. This supplement might not be the sole reason, but I believe it plays a significant role.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
- All Researches
9
We explored how turmeric curcumin can influence liver health, specifically focusing on its effect on Ca(2+) levels in rat liver cells. The study showed that curcumin blocks the activation of TRPM2 channels, which are linked to liver damage from oxidative stress. When we introduced 5µM of curcumin, it effectively prevented increases in harmful calcium levels caused by substances like hydrogen peroxide and paracetamol. These results support curcumin's role as a hepatoprotective agent, highlighting its potential in treating liver disorders related to oxidative stress.
Read More
9
We explored how curcumin can protect against liver damage caused by paracetamol overdose in male Wistar rats. The study involved four groups, including those receiving curcumin, paracetamol, and a combination of both. Our findings revealed that curcumin significantly improved liver health by restoring antioxidant activity and reducing harmful inflammation compared to the paracetamol-only group. This research highlights curcumin's potential as a protective agent against liver toxicity, although further studies are needed to clarify its exact mechanism of action.
Read More
9
We investigated how turmeric curcumin might help with liver issues caused by concanavalin A in mice. By giving curcumin before exposing the mice to the liver damage, we observed significant protection against T cell-mediated hepatitis. This was shown through lower levels of liver enzymes and less liver cell death. Additionally, curcumin reduced inflammation and oxidative stress in the liver, which are key contributors to liver damage. Overall, our findings suggest that curcumin offers protective benefits against certain types of liver injuries.
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9
We investigated how curcumin, a compound from turmeric, affects liver inflammation caused by endotoxins. Using mice, we pre-treated them with two doses of curcumin before introducing an endotoxin. The results were promising: curcumin significantly reduced inflammation in the liver, shown by fewer immune cells sticking to blood vessels and a restoration of normal blood flow. Overall, curcumin may offer a natural way to manage liver inflammation effectively.
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8
We analyzed the impact of Indian culinary spices on managing liver cancer, focusing on the TGF-β pathway. Our investigation highlighted turmeric and its active component, curcumin, as having the strongest potential for treating inflammation-induced liver cancer.
The evidence we found suggests that these spices could play an important role in combating the liver issues linked to hepatitis and cirrhosis, largely by regulating inflammatory responses.
While turmeric shows promise, the research further emphasizes the need for ongoing studies to fully understand its effectiveness.
The evidence we found suggests that these spices could play an important role in combating the liver issues linked to hepatitis and cirrhosis, largely by regulating inflammatory responses.
While turmeric shows promise, the research further emphasizes the need for ongoing studies to fully understand its effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective hepatitis treatment
28 people found this helpful
After covid, my husband's liver was severely affected (the tests were akin to hepatitis). He took SAMe (Heptral from the pharmacy) and this curcumin for three weeks. Together, these two treatments yielded excellent test results. We chose this specific curcumin because it’s very well absorbed and deemed most effective by our nutritionist. I believe we will continue taking curcumin for prevention. I will certainly reorder this.
Read More
9
Normal liver values
9 people found this helpful
Post-Hepatitis A liver values are normal. I've taken silymarin, or milk thistle, before while recovering from Hepatitis A. My liver tests were back to normal three months later, and I am grateful for this product. Now, I'm taking it for post-infectious syndrome and feel significantly better.
Read More
7.5
Positive outcome reported
352 people found this helpful
Can be helpful for liver disease. I have used this product for over three years since my diagnosis of medication-induced liver damage. Initially, my GI specialist only hoped to halt progress after following strict dietary guidelines. However, I noticed positive changes, including normal scans and blood work, confirming my liver's improvement after making various lifestyle changes. This supplement might not be the sole reason, but I believe it plays a significant role.
Read More
6
Reduced hepatic episodes
3 people found this helpful
Decent. I have been taking this supplement for nearly two years due to drug-induced hepatitis from a past overdose. I believe it has helped lessen the frequency and severity of hepatic episodes, though I only take vitamin D alongside. I recommend discussing it with a doctor before starting, as individuals with sensitive livers should be cautious about any supplement.
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6
Stable and effective
2 people found this helpful
I take a higher dosage than recommended due to my hepatitis C. I’ve used it for about six months and have experienced no side effects. I consulted with Jarrow, and they informed me that their product met ingredient testing successfully. My upcoming lab tests will show any improvement in my liver enzymes.
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Frequently Asked Questions
9
Effective hepatitis treatment
28 people found this helpful
After covid, my husband's liver was severely affected (the tests were akin to hepatitis). He took SAMe (Heptral from the pharmacy) and this curcumin for three weeks. Together, these two treatments yielded excellent test results. We chose this specific curcumin because it’s very well absorbed and deemed most effective by our nutritionist. I believe we will continue taking curcumin for prevention. I will certainly reorder this.
References
- Asoka AS, Kolikkandy A, Nair B, Kamath AJ, Sethi G, et al. Role of Culinary Indian Spices in the Regulation of TGF-β Signaling Pathway in Inflammation-Induced Liver Cancer. Mol Nutr Food Res. 2024;68:e2300793. 10.1002/mnfr.202300793
- Ali M, Asghar E, Ali W, Mustafa G, Ansari IA, et al. Screening of Multitarget Compounds against Acetaminophen Hepatic Toxicity Using In Silico, In Vitro, and In Vivo Approaches. Molecules. 2024;29. 10.3390/molecules29020428
- Guo X, Zheng B, Wang J, Zhao T, Zheng Y. Exploring the mechanism of action of Chinese medicine in regulating liver fibrosis based on the alteration of glucose metabolic pathways. Phytother Res. 2024;38:4865. 10.1002/ptr.7667
- Yusuf H, Novitasari EKDD, Purnami NLW, Mahbub AW, Sari R, et al. Formulation Design and Cell Cytotoxicity of Curcumin-Loaded Liposomal Solid Gels for Anti-Hepatitis C Virus. Adv Pharmacol Pharm Sci. 2022;2022:3336837. 10.1155/2022/3336837
- Hv S, V Thomas J, Hs V, K S. An open label, single arm, prospective clinical study to evaluate liver safety and tolerability of PUREMERIC™ (standardized extract from ) in healthy subjects. Toxicol Rep. 2021;8:1955. 10.1016/j.toxrep.2021.11.022
- Witika BA, Makoni PA, Matafwali SK, Mweetwa LL, Shandele GC, et al. Enhancement of Biological and Pharmacological Properties of an Encapsulated Polyphenol: Curcumin. Molecules. 2021;26. 10.3390/molecules26144244
- Ailioaie LM, Litscher G. Curcumin and Photobiomodulation in Chronic Viral Hepatitis and Hepatocellular Carcinoma. Int J Mol Sci. 2020;21. 10.3390/ijms21197150
- Hesari A, Ghasemi F, Salarinia R, Biglari H, Tabar Molla Hassan A, et al. Effects of curcumin on NF-κB, AP-1, and Wnt/β-catenin signaling pathway in hepatitis B virus infection. J Cell Biochem. 2018;119:7898. 10.1002/jcb.26829
- Tang HH, Li HL, Li YX, You Y, Guan YY, et al. Protective effects of a traditional Chinese herbal formula Jiang-Xian HuGan on Concanavalin A-induced mouse hepatitis via NF-κB and Nrf2 signaling pathways. J Ethnopharmacol. 2018;217:118. 10.1016/j.jep.2018.02.003
- Kheradpezhouh E, Barritt GJ, Rychkov GY. Curcumin inhibits activation of TRPM2 channels in rat hepatocytes. Redox Biol. 2016;7:1. 10.1016/j.redox.2015.11.001
- Soliman MM, Abdo Nassan M, Ismail TA. Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats. BMC Complement Altern Med. 2014;14:457. 10.1186/1472-6882-14-457
- Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, et al. Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. 2014;63:1137. PubMed
- Wang C, Nie H, Li K, Zhang YX, Yang F, et al. Curcumin inhibits HMGB1 releasing and attenuates concanavalin A-induced hepatitis in mice. Eur J Pharmacol. 2012;697:152. 10.1016/j.ejphar.2012.09.050
- Kim K, Kim KH, Kim HY, Cho HK, Sakamoto N, et al. Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway. FEBS Lett. 2010;584:707. 10.1016/j.febslet.2009.12.019
- Lukita-Atmadja W, Ito Y, Baker GL, McCuskey RS. Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin. Shock. 2002;17:399. PubMed
