NOW Supplements Inositol Powder

We conducted a study to understand how inositol, a naturally occurring sugar alcohol, influences anxiety levels in laying hens. Our focus was on the behavior of Lohmann LSL lite hens, which were fed two different diets—one rich and one deficient in protein—while receiving either pure inositol or high levels of phytase.

Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.

Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.

Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.

9.5

Effective alternative treatment

Most Useful Review

Proven effective for OCD and anxiety! I was initially sceptical about inositol but saw significant improvement in my son's severe OCD and my own anxiety after following a prescribed dosage. Despite being used to medications with severe side effects, inositol has shown promising results. It seems it requires a high dose for mental health conditions, but side effects are mild. I highly recommend it as a viable option.

Acne

SCIENTIFIC SCORE

Moderately Effective

Based on 7 Researches

Myo-inositol improves acne symptoms

Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome.

Most Relevant Research

We explored the effects of myo-inositol (MYO) on acne among young women diagnosed with polycystic ovary syndrome (PCOS). The study included 50 participants who underwent treatment with MYO for six months, focusing on its potential to improve the often frustrating skin issues linked to PCOS.

At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.

Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.

This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.

9.5

Acne prevention benefits

Most Useful Review

Myo-inositol has proven effective for PCOS and is essential in managing beauty and youth. I've noticed improvements in my skin, as it prevents acne and promotes hair growth. Additionally, it aids in sleep and mood. After taking it, I experienced fewer breakouts, and it significantly improved my overall health alongside fertility, making it a vital supplement to my routine.

Cancer

SCIENTIFIC SCORE

Likely Very Effective

Myo-inositol affects prostate cancer cells

Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.

Most Relevant Research

We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.

Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.

Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.

Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).

9.5

Post-surgery support

Most Useful Review

So far so fantastic! I cannot afford similar products elsewhere, and this has helped me immensely, especially after my hysterectomy and during early menopause due to having cancer. I will continue purchasing, and now my friends are doing the same.

Common Cold

After using it for two months, I can honestly say it relieved the symptoms of polycystic ovary syndrome, like severe cramps and skin issues. Additionally, it has substantially decreased my appetite for sugar. I recommend taking two pills a day, four hours before bed to avoid lethargy.

Hair Loss

Inositol synthesis and hair loss

SYNTHESIS OF INOSITOL IN MICE.

Most Relevant Research

We explored whether inositol, when paired with pantothenic acid, impacts hair health in mice. The study revealed that mice can synthesize inositol, but this synthesis relies heavily on the presence of pantothenic acid in their diet. When pantothenic acid was absent, inositol production did not occur.

We noticed that cultures taken from the intestines of mice that naturally recovered from hair loss produced significantly higher levels of inositol. In contrast, similar cultures from hairless mice generated much less inositol. Additionally, we observed that inositol exists in both free and combined forms within various biological materials. Strikingly, we found that a deficit of inositol can arise even if inositol is dietary, provided pantothenic acid is missing.

Overall, though this research provides insights into inositol's synthesis and its connection with hair loss, it does not conclusively demonstrate that inositol alone effectively treats hair loss—particularly in the absence of pantothenic acid.

9.5

Thicker hair now

Most Useful Review

Promotes hair growth! Years ago, I faced severe hair loss, including thinning and bald spots. I tried numerous remedies like biotin and special shampoos without success as I was severely anaemic. Eventually, I discovered that insufficient iron causes hair loss in women. After trying inositol powder, I saw remarkable results within a month—my bald spots filled in, and my hair became noticeably thicker. I've returned for more and continue to research related health supplements.

Neuropathy

For 25 years, I've experienced numbness in my chin after jaw surgery, while my husband has had neuropathy in his toes, leading to a lack of sensation. We both take this twice a day at 1/4 tsp. and feel nearly normal within days. It helps restore sensation in the injured nerve, but only while taking it. It's not a cure, as you will numb again if you stop. It is far superior to expensive drugs with side effects and tastes like sugar.

Heart Attack

SCIENTIFIC SCORE

Likely Very Effective

ITPP enhances heart attack recovery

Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells.

Most Relevant Research

We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.

Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.

In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.

Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.

9.5

Various benefits

Most Useful Review

Inositol is beneficial for numerous conditions, from diabetic nerve pain to high cholesterol and even polycystic ovary syndrome. It's been shown to help balance chemicals, aiding conditions like panic disorders and potentially reducing the risk of heart attack through improved cholesterol levels.

Buzhongyiqi Decoction Protects Against Loperamide-Induced Constipation by Regulating the Arachidonic Acid Pathway in Rats.

Most Relevant Research

We aimed to understand the effects of Buzhongyiqi decoction (BZYQD) on constipation, particularly how it influences various metabolic pathways. In our exploration, we conducted experiments on rats experiencing loperamide-induced constipation. Following treatment with BZYQD, we observed a notable increase in the small intestinal transit rate, suggesting improved digestive movement.

Our findings also revealed that BZYQD helped to reduce pathological damage in the colon. Interestingly, one of the key factors we looked at was inositol, a metabolite whose levels were significantly affected by the treatment. We discovered that BZYQD not only increased serum levels of inositol but also enhanced the levels of motilin and gastrin, hormones that play important roles in regulating gastrointestinal motility.

Additionally, our analysis showed that BZYQD impacted inflammatory pathways by reducing the production of pro-inflammatory mediators and down-regulating markers like cyclooxygenase-2. These effects suggest a comprehensive approach to managing constipation might involve multiple metabolic pathways, with inositol being a notable component. Overall, our study suggests that BZYQD can protect against constipation, with inositol contributing to this beneficial effect, though further studies are needed to isolate its specific impact.

8.8

Patient favourite

Most Useful Review

This Inositol supplement is the best quality I have found for high potency at an affordable price. It takes time to exhibit its benefits, particularly for chronic constipation, but it has the potential to greatly alleviate various health issues. My patients and I find it incredibly helpful.

Migraine

Decreased migraine frequency

Most Useful Review

I’ve been taking Inositol Powder for allergies combined with quercetin, and it seems to reduce the intensity and duration of my migraine headaches. However, once I ran out of inositol, the headaches returned. It’s part of the B vitamin family, and along with a mega B complex, this combination works well for me.

Menopause

SCIENTIFIC SCORE

Possibly Effective

Based on 9 Researches

Myo-Inositol Support in Menopause

Tonsil-Derived Mesenchymal Stem Cell-Derived Small Extracellular Vesicles (sEVs) Restore Myo-Inositol Production in LPS-Treated Skeletal Muscle.

Most Relevant Research

We investigated whether small extracellular vesicles (sEVs) derived from human palatine tonsil mesenchymal stem cells could boost myo-inositol levels in the context of menopause. This was particularly interesting given that menopausal women are prone to chronic inflammation due to physiological changes and related issues like metabolic syndrome.

To explore this, we treated mice with lipopolysaccharides (LPS) to simulate inflammation and assessed how the inclusion of T-MSC sEVs influenced myo-inositol production. After treatment, we measured levels of proteins involved in inositol synthesis in skeletal muscle and checked the serum for inositol levels.

Our findings are encouraging and suggest that T-MSC sEVs might help mitigate some effects of chronic inflammation linked to menopause. By supporting skeletal muscle mass and maintaining myo-inositol levels, these sEVs could be an effective strategy for improving metabolic health in menopausal women. This study sheds light on a potential new approach to tackle metabolic disturbances during this life stage.

9.5

Cycle support

Most Useful Review

I am 40 and have a family history of early menopause. This supplement has helped me resume my cycle after a three-month delay. I took one capsule daily, and after three weeks, I saw positive results in my tests regarding menopause. I hope to maintain these results moving forward.

Dizziness

Five stars, this product is easy to take without dealing with gelatin capsules. It has assisted with my insulin resistance. However, be cautious with the dosage since it can lower blood sugar and cause dizziness and low energy. I revised my dosage but am fine now. It’s an excellent product—affordable too, which is important for me, especially since I have PCOS.

Insomnia

My senior mother has relied on inositol for over five years for her sleep issues. She struggled with insomnia, waking frequently at night, but inositol has transformed her sleep. Though it may not work for everyone, I highly recommend it.

Bloating

SCIENTIFIC SCORE

Moderately Effective

Based on 2 Researches

Combined treatment improves bloating

Beta-glucan, inositol and digestive enzymes improve quality of life of patients with inflammatory bowel disease and irritable bowel syndrome.

Most Relevant Research

We set out to evaluate how a mixture of beta-glucan, inositol, and digestive enzymes could help ease gastrointestinal discomfort, particularly bloating, in patients suffering from both inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). Our study involved 43 patients who were already receiving their standard medication. They were divided into two groups: one continued with their regular treatment, while the other received additional support from our special mixture for four weeks.

After this treatment period, we observed notable improvements in the group that received the beta-glucan, inositol, and digestive enzymes. Many patients reported reduced bloating, flatulence, and abdominal pain. Overall, their clinical condition showed significant enhancement, suggesting that these combined ingredients can positively impact the quality of life for individuals battling these challenging gastrointestinal issues.

5.8

Bloating with dosage

Most Useful Review

This product has helped me manage my obsessive thoughts and stabilise my mood. However, the higher dose I need gives me gas, bloating, and loose stools. Still, a little physical discomfort is better than enduring mental unhappiness.