NOW Supplements MSM 1000 mg

Supplement Facts

Serving Size: 2 Veg Capsules

Amount Per Serving

%DV

MSM (Methylsulfonylmethane)

2 g (2,000 mg)

The product is found useful for the following medical conditions

Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.

Most Relevant Research

In a well-structured randomized, double-blind, placebo-controlled trial, we explored how methylsulfonylmethane (MSM) affects those experiencing mild knee pain. The study involved 88 healthy Japanese participants, split evenly into two groups where one received 200 mg of MSM while the other received a placebo for 12 weeks.

By measuring the total score on the Japanese Knee Osteoarthritis Measure (JKOM) at the end of the trial, we found that the MSM group showed a significant improvement compared to the placebo group. Specifically, total JKOM scores changed markedly, with an improvement in knee and systemic health reported by participants who took MSM.

Our findings suggest that MSM might be beneficial for individuals with mild knee pain, marking it as a useful supplement for enhancing joint health. The positive outcomes underscore the potential of MSM as a supportive treatment option for managing mild arthritic conditions.

9.5

Miraculous improvements

Most Useful Review

They should add this to the tap water like fluoride, allowing everyone to heal. I can't express how much this supplement has improved my life. I was recently diagnosed with rheumatoid arthritis in both shoulders, and I've resolved to manage my pain without narcotics. This has been miraculous. The pain diminished, my gastric problems are easing, my skin appears better, and I feel progressively healthier each day. Amazingly, there are no adverse reactions or known drug interactions. It seems incredible that more people aren't aware of its benefits, leading me to share this information with all who will listen.

Hair Loss

SCIENTIFIC SCORE

Likely Very Effective

MSM shows promise for hair loss

EVALUATION OF THE EFFECT OF TOPICALLY APPLIED METHYLSULFONYLMETHANE AND THEIR COMBINATION WITH MINOXIDIL SOLUTION FOR IMPROVEMENT OF HAIR GROWTH IN MALE MICE.

Most Relevant Research

We explored the potential of Methylsulfonylmethane (MSM) as a treatment to minimize hair loss. In our study, we used twenty male Wister Albino mice, carefully dividing them into four groups to test different treatments: a control group with distilled water, a group treated with Minoxidil, one with MSM, and a group receiving a combination of MSM and Minoxidil.

Over the course of the study, we observed that the mice given MSM experienced notable improvements compared to the control group. Specifically, hair growth increased, and hair follicle numbers were significantly higher in the groups treated with MSM, whether alone or in combination with Minoxidil.

Additionally, we found a reduction in tissue levels of 8-isoprostane—a marker of oxidative stress—in the medicated groups, pointing to MSM’s antioxidant properties. There was also an increase in vascular endothelial growth factor, suggesting enhanced blood supply to the hair follicles.

Our overall conclusion is that MSM shows promise in reducing hair loss through its remarkable antioxidant and anti-inflammatory effects in male mice. This research indicates that MSM could be a valuable ally in the fight against hair loss.

9.5

Significant hair growth

Most Useful Review

Great for making my hair longer! As a 45-year-old woman who lost substantial hair after having two children, I researched hair loss. While my hair did grow back, it never reached the length it once was - two inches below my bra strap. My pregnancies seemed to shorten the anagen phase of my hair growth, leading to a consistent length that was disappointing. I tried various supplements, sceptically expecting little change. However, after taking these supplements for just under four months, I was shocked to see my hair reached the middle of my bra strap! Now, on my third bottle, my hair has grown a total of 2 inches longer in five months. I’m keen to keep using this to restore my hair’s former length!

Rheumatoid Arthritis

MSM and BA show limited effects

The "MESACA" study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis.

Most Relevant Research

In our clinical trial, we investigated the effects of methylsulfonylmethane (MSM) combined with boswellic acids (BA) on individuals suffering from knee arthritis, a chronic condition often characterized by joint pain and inflammation. We enrolled 60 participants who were randomly divided into two groups: one group received the MSM and BA treatment for 60 days, and the other group was given a placebo.

Over the follow-up periods of 2 and 6 months, we measured pain levels using a visual analog scale (VAS) and assessed joint function with the Lequesne index (LI). While we found that participants taking MSM and BA reported higher pain levels than those on the placebo after 2 months, these differences did not persist at the 6-month mark. Furthermore, when evaluating joint function, we noted no significant differences between the two groups.

However, one notable finding was that those receiving the combination treatment needed fewer anti-inflammatory drugs compared to the placebo group at both follow-up points. Despite the reduced reliance on these medications, we concluded that combined treatment with MSM and BA did not significantly improve pain or joint function compared to placebo.

Miraculous healing

Most Useful Review

They should add this to tap water like fluoride for universal healing. Having recently been diagnosed with rheumatoid arthritis in both shoulders, I've managed the pain without narcotics. This supplement has greatly improved my situation—less pain, resolving gastric issues, and an overall enhancement in my well-being. It's remarkable that there are no adverse reactions or known drug interactions associated with it.

Common Cold

Hello everyone! I trust this brand's supplements! I’ve tried various ones, all of excellent quality, great price, and good ingredients. I bought this product for immune support during colds, and it copes with this task perfectly. The packaging is convenient, with a tight lid, and the capsules are of a standard size, making them easy to use.

Abscess

Higher amebiasis risk in MSM

Increased risk for Entamoeba histolytica infection and invasive amebiasis in HIV seropositive men who have sex with men in Taiwan.

Most Relevant Research

We investigated how HIV-infected men who have sex with men (MSM) are affected by Entamoeba histolytica, the parasite responsible for invasive amebiasis (IA), which can lead to conditions like liver abscesses. During our study at the National Taiwan University Hospital, we looked at medical records of HIV-positive patients diagnosed with IA between 1994 and 2005.

From over a thousand HIV-infected individuals, we found that 64 patients, mostly MSM, experienced 67 total episodes of IA. Interestingly, the average CD4 count, a crucial indicator of immune system health, was significantly higher among patients with IA compared to the overall group of HIV patients. This suggests that despite being HIV-positive, many MSM can still mount an immune response against the infection.

Most patients responded well to treatment with metronidazole, with fever subsiding quickly. Importantly, our analysis revealed that MSM face a much higher risk of getting infected compared to other groups. This research underscores the need for targeted prevention strategies in this population to curb the spread of amoebic infections.

Natural healing success

Most Useful Review

I was told by my dentist that I needed an emergency root canal for my infected tooth. I had a small abscess in my gums above the infected tooth. After taking two MSM sulfur tabs daily, my abscess is gone, the redness has faded, and my gums no longer bleed. My "dead" tooth is very much alive. I am relieved that this natural supplement healed my issues and will definitely reorder.

Bone Pain

Effective pain relief

Most Useful Review

This product is working very well for me. I had one knee replaced and the other is bone-on-bone. The replaced knee caused me more pain than the deteriorating one. My chiropractor recommended MSM to help alleviate the pain and swelling. I began with 2000 mg and now take up to 4000 mg, depending on my activity level. It has significantly reduced my pain, and I’ve ceased taking ibuprofen for now. I am very pleased it remains effective, and as long as it keeps my pain level low, I won't need a second knee replacement.

Bursitis

Immediate pain relief

Most Useful Review

MSM worked wonders for my severe hip pain caused by bursitis. Almost immediately after taking it, my pain ceased. I now walk easily without discomfort; the only side effect was mild gas, which cleared up after a few days.

Eczema

Cleared eczema completely

Most Useful Review

If you have eczema, I highly recommend trying this! This brand is of excellent quality and has no moisture in the bottle. Someone mentioned it cleared their eczema, so I gave it a go. I have struggled with eczema on my hands, which at times made working painful. This product completely resolved my eczema, but if I skip days, it returns. I enthusiastically recommend this for anyone facing skin issues.

Cold

Flu symptom reduction

Most Useful Review

Keeps me well! I will sing the praises of MSM forever. It reduced my flu symptoms by half and any cold I catch as well. Additionally, it has transformed my hair care routine, making brushing painless and eliminating my acne breakouts. I've used it for about a year now and wholeheartedly recommend it!

Ear Infection

Seasonal sinus infection control

Most Useful Review

Reoccurring sinus infections. This supplement has prevented me from experiencing seasonal sinus infections. Since I started taking it three years ago, I haven’t had a sinus infection.

Psoriasis

Effective against psoriasis

Most Useful Review

My daughter, who has plaque psoriasis on her scalp, finds MSM lotion more effective than hydrocortisone. This miracle supplement also addresses seasonal allergies. While I initially had some gas as a detox symptom, I experienced no side effects after a month. I believe it could resolve her skin issues once she is old enough for oral use.

Osteoporosis

MSM enhances bone cell differentiation

Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells.

Most Relevant Research

We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.

Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.

Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.

7.5

Manageable pain

Most Useful Review

Recommended by a trusted doctor, I take this for several conditions, including osteoporosis. I avoided opioids due to addiction and found that after taking this for almost three weeks, my pain has become more manageable, and I feel more alert.

Flu

Keeps me well. I will sing the praises of MSM until I die. It cut my flu symptoms in half and I tell everyone about it. My skin and hair are so soft; brushing my long hair is no longer painful. I have tried other more expensive brands but haven’t noticed any differences in benefits. I’m a 48-year-old woman and since using MSM for about a year, I haven’t had a single breakout. I say go for it and see how it works for you!

Migraine

SCIENTIFIC SCORE

Likely Very Effective

Based on 2 Researches

MSM improves migraine management

Acute migraine medication adherence, migraine disability and patient satisfaction: A naturalistic daily diary study.

Most Relevant Research

We aimed to understand how adherence to migraine-specific medications (MSMs) influences migraine-related disability and patient satisfaction. Over three months, 337 participants used daily electronic diaries to track their migraine experiences, including the medications they took and their satisfaction with these treatments.

It was insightful to see that participants took their acute medications on a staggering 96.5% of the days they recorded migraines. Among the medications used, MSMs were the most common at 58%, followed by over-the-counter analgesics and opiates/barbiturates. We found that people tended to reach for medication when their pain was mild most often.

Our analysis showed that when individuals used MSMs during mild pain, they experienced the least daily disability and reported the highest satisfaction with their medications. This implies that using MSMs earlier, especially at the onset of milder symptoms, can significantly improve a patient's overall experience with migraines.

In conclusion, our study highlights the benefits of starting treatment with MSMs for better outcomes in managing migraine-related challenges and achieving greater satisfaction with acute medication usage.

Caution advised

Most Useful Review

I must warn those prone to migraines that this product triggered a migraine for three days after I began it. I initially took the full dose, but realised that it should be introduced gradually for those with headache sensitivity. After pausing use, I'm now cautiously testing a smaller dosage.

Bloating

Bloating as side effect

Most Useful Review

This is evidently a good and beneficial product, but I experienced one of the common side effects—bloating—within days of starting. Weeks after discontinuing, I'm still dealing with it, though my healthy diet has been beneficial.

Headache

SCIENTIFIC SCORE

Likely Very Effective

Erenumab reduces migraine medication use

Reduction in acute migraine-specific and non-specific medication use in patients treated with erenumab: post-hoc analyses of episodic and chronic migraine clinical trials.

Most Relevant Research

We explored how erenumab impacts the use of acute headache medication, especially migraine-specific medications (MSM). The study analyzed data from two major clinical trials involving patients with episodic migraine (EM) and chronic migraine (CM). Participants received either erenumab or placebo over a set period, allowing us to compare medication usage accurately.

Our findings indicate that treatment with erenumab led to a significant decrease in the number of days patients used acute headache medications, particularly in those relying on MSM. This reduction was observed in both episodic and chronic migraine patients, suggesting that erenumab not only helps manage migraines but may also help mitigate the need for additional acute treatment.

Overall, these results highlight the potential benefits of erenumab in addressing not just the frequency of migraines but also reducing dependence on medications traditionally used for acute migraine relief.

9.5

Eased headaches

Most Useful Review

I've found that this supplement helps with inflammation, particularly my stiff shoulders and associated headaches. After taking one tablet daily, my shoulder stiffness has improved.

NOW Supplements MSM 1000 mg

The product is found useful for the following medical conditions

Back Pain

Acne

Allergies

Arthritis

Hair Loss

Rheumatoid Arthritis

Common Cold

Abscess

Bone Pain

Bursitis

Eczema

Cold

Ear Infection

Psoriasis

Osteoporosis

Flu

Migraine

Bloating

Headache