NOW Supplements MSM

I ordered this dietary supplement for my elderly father, who has issues with bone structure. I felt significant relief due to MSM's inclusion in his regimen. He takes Solgar Omega-3 EPA, Now Foods Chondroitin Sulfate, and MSM in conjunction. We prefer pure chondroitin without glucosamine, given his elevated blood sugar levels. This combination can be consumed seasonally, in spring and autumn. He hasn't experienced any bloating or digestive troubles, contrary to some reviews.

Cardiovascular Disease details

MSM (methylsulfonylmethane) is a sulphur-containing compound essential for the health, repair, and renewal of bones, joints, cartilage, skin, and connective tissue. MSM significantly reduces inflammation and accelerates recovery after injuries. It prevents the degradation of cartilage and connective tissue, protecting bones in the joints from friction. One of the most common uses of MSM is to alleviate joint or muscle pain. Studies indicate that it alleviates pain in individuals with degenerative joint disease and frequent discomfort in the knees, back, arms, and hips.

Ear Infection details

Seasonal sinus infection control

10 people found this helpful

Reoccurring sinus infections. This supplement has prevented me from experiencing seasonal sinus infections. Since I started taking it three years ago, I haven’t had a sinus infection.

High Cholesterol details

3 people found this helpful

Methylsulfonylmethane has powerful anti-inflammatory properties, particularly for treating joint inflammation. It also aids in synthesising collagen and keratin, vital for maintaining skin elasticity and promoting hair and nail growth. I take it regularly and am very pleased; my joints no longer hurt, and I feel great! I also apply an MSM cream for better results!

Osteoporosis details

MSM enhances bone cell differentiation

Kim DN, Joung YH, Darvin P, Kang DY, Sp N, et al. Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells. Mol Med Rep. 2016;14:460. doi:10.3892/mmr.2016.5274

We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.

Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.

Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.

Pain relief noted

Most Useful Review

2 people found this helpful

Excellent! My mother is quite elderly and suffers from severe osteoporosis, as well as occasional low back pain following a lower back injury, which caused her to bend over. Due to concerns about side effects from Western medicine, alongside taking Life Extension’s Bone Strength Collagen Formula, I also added MSM for its anti-inflammatory benefits and to strengthen cartilage and connective tissue. After nearly a month, my mother can finally straighten her back and has experienced significant pain relief. This product has been beneficial for her back pain, and I plan to continue purchasing it.

Sleep Apnea details

I took it to a work colleague whose knees ached so much that she could not sleep at night. After two weeks of taking it, she reported that her knees stopped hurting. I was pleasantly surprised by such a swift result. I will be ordering more, as I have already received requests from others with similar issues.

Swollen Lymph Nodes details

45 people found this helpful

After joining a weight loss marathon with knee pain, I started taking MSM and resumed training within a day. I felt that MSM enhanced my weight loss, completely alleviating my swelling. My hair grew noticeably, and I experienced a boost in energy and improved sleep, all thanks to MSM. I even secured second place in the marathon!

Tendonitis details

Notable pain reduction

8 people found this helpful

It worked all over! It's been three weeks since I started taking it, hoping it would help with stiff shoulders, tendonitis, skin quality, hay fever, and hair quality. Stiff shoulders are almost bother-free now, and while my tendonitis isn't cured, the pain is less than before. My skin texture has improved, and the lichen pilaris on my arms and buttocks is much smoother. In combination with mild medication, my hay fever symptoms are greatly reduced. My hair feels moist and heavy after shampooing. I plan to continue as everything has slowly improved since starting.

Allergies details

Hewlings S, Kalman DS. Evaluating the Impacts of Methylsulfonylmethane on Allergic Rhinitis After a Standard Allergen Challenge: Randomized Double-Blind Exploratory Study. JMIR Res Protoc. 2018;7:e11139. doi:10.2196/11139

Likely Very Effective

MSM offers allergy symptom relief

We aimed to understand how methylsulfonylmethane (MSM) impacts symptoms of allergic rhinitis through a well-structured randomized, double-blind study.

Participants, who were prone to allergic responses, were tested after taking varying doses of MSM following allergen exposure.

Interestingly, the results showed that MSM significantly eased nasal symptoms and improved airflow, making it a potential alternative to conventional allergy medications.

We’re excited by the findings, as MSM appeared effective without common side effects associated with typical treatments.

Miracle supplement

Most Useful Review

88 people found this helpful

I have endured severe allergies for over six years, worsening from mild reactions to persistent issues requiring regular treatments. I tried numerous remedies, and then I discovered MSM. After starting it without any allergy medications, I noticed marked improvements in my breathing within just two days. My doctor was astonished at the lack of inflammation in my nose during peak allergy season. I also introduced a co-worker to MSM, and he experienced instant relief from his allergy symptoms after taking it. I can’t recommend it enough to anyone suffering as I once did—it's truly a miracle supplement!

Bacterial Infection details

Effective inflammation relief

11 people found this helpful

MSM is a natural anti-inflammatory that I've relied on for years, especially valuable when I owned a horse. It effectively reduces pain and inflammation throughout my body and facilitates the absorption of other nutrients. This high-quality product is safe for both humans and animals, and after experiencing its quick and lasting effects, I can't imagine life without it. It's particularly helpful for body aches, injuries, and infections such as lung inflammation due to asthma. The NOW brand provides excellent value, making it indispensable in my home.

Chronic Cough details

2 people found this helpful

I've been taking this product almost daily since early December. I experienced significant inflammation in my fingers and wrist joints and acne from stress. Now, I don’t worry about arthritis as I’ve improved tremendously. I used to have chronic cough due to allergic rhinitis, but I hardly suffer from it anymore unless exposed to allergens. This product has greatly helped with my symptoms and is fantastic for the price!

Hypothyroidism details

Excellent! MSM, by eliminating sulphur deficiency in the body, helps me alleviate joint pain that developed due to stress and hypothyroidism. The effect becomes noticeable by the end of the first jar; I have already ordered the third. Of course, a diet that reduces inflammation is necessary, as improvements occur only in combination. The taste is neutral, the capsule size is small and very convenient to take. The large packaging is an advantage for me; it lasts almost three months with my regimen.

Pelvic Pain details

270 people found this helpful

Methylsulfonylmethane, a sulphur-based compound found in various foods, is often consumed as a supplement due to its minimal dietary presence. Since starting MSM, my seasonal joint pain has completely vanished. I've also added Chondroitin Glucosamine and turmeric to my regimen. Additionally, my skin tone has evened out, my nails have strengthened, and my hair has stopped falling out. I highly recommend it.

Acne details

17 people found this helpful

Edited my review, please like ❤️ and share my experience. After two weeks, I noticed significant improvement; my acne almost vanished while taking MSM. Even my hair seemed healthier. The quality is excellent, and the formula is suitable for those over 18. I was hoping for clearer skin, and it seems effective. Support me in sharing this!

Arthritis details

MSM improves knee osteoarthritis symptoms

Possibly Effective

Based on 13 Researches

Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006;14:286.

We conducted a randomized, double-blind, placebo-controlled trial exploring the effects of methylsulfonylmethane (MSM) on knee osteoarthritis pain. Fifty adults aged 40 to 76 participated, taking either MSM or a placebo for 12 weeks.

While MSM did show improvements in pain and physical function, there was no significant effect on stiffness or overall symptom scores. This means that while MSM might help with certain aspects of osteoarthritis, the overall benefits and long-term safety need more research.

Miraculous improvements

Most Useful Review

233 people found this helpful

They should add this to the tap water like fluoride, allowing everyone to heal. I can't express how much this supplement has improved my life. I was recently diagnosed with rheumatoid arthritis in both shoulders, and I've resolved to manage my pain without narcotics. This has been miraculous. The pain diminished, my gastric problems are easing, my skin appears better, and I feel progressively healthier each day. Amazingly, there are no adverse reactions or known drug interactions. It seems incredible that more people aren't aware of its benefits, leading me to share this information with all who will listen.

Common Cold details

Hello everyone! I trust this brand's supplements! I’ve tried various ones, all of excellent quality, great price, and good ingredients. I bought this product for immune support during colds, and it copes with this task perfectly. The packaging is convenient, with a tight lid, and the capsules are of a standard size, making them easy to use.

Psoriasis details

Cured psoriasis completely

22 people found this helpful

This supplement effectively treats skin conditions. I initially took it for my hair, but my friend's boyfriend had psoriasis; he completely got rid of it after starting MSM! Doctors prescribed various ointments with no success, while this supplement worked wonders for psoriasis. He took 2 tablets of 750 mg plus one 200 mg magnesium tablet each day for 2 weeks, totalling 1500 mg of sulfur daily. All inflammation cleared up in that time, and now he takes 750 mg of sulfur and 200 mg of magnesium. If this was helpful, give a like! 👍

Rash details

Rashes improving noted

Clean face without acne! I suffer from rashes and subcutaneous comedones, which cause considerable trouble as they often become inflamed. However, I have found a remedy that has almost eliminated all the rashes on my face. I will continue until my skin is perfect.

Adenoiditis details

Allergy relief achieved

MSM is an organic product containing sulphur found in all living organisms, related to oxygen. It helps me significantly with throat allergies, various colds, and bone and joint issues. Additionally, MSM is recommended for maintaining eye health.

Flu details

13 people found this helpful

Keeps me well. I will sing the praises of MSM until I die. It cut my flu symptoms in half and I tell everyone about it. My skin and hair are so soft; brushing my long hair is no longer painful. I have tried other more expensive brands but haven’t noticed any differences in benefits. I’m a 48-year-old woman and since using MSM for about a year, I haven’t had a single breakout. I say go for it and see how it works for you!

Bone Pain details

Effective pain relief

This product is working very well for me. I had one knee replaced and the other is bone-on-bone. The replaced knee caused me more pain than the deteriorating one. My chiropractor recommended MSM to help alleviate the pain and swelling. I began with 2000 mg and now take up to 4000 mg, depending on my activity level. It has significantly reduced my pain, and I’ve ceased taking ibuprofen for now. I am very pleased it remains effective, and as long as it keeps my pain level low, I won't need a second knee replacement.

Chronic Fatigue Syndrome details

Improved overall health

1 people found this helpful

I've found it easier to manage fatigue. This supplement works wonders, as my energy levels have improved and my overall health has enhanced. I feel less fatigued throughout the day and am confident in continuing its use.

Cold details

Perfect for immune support

Greetings everyone! I trust this brand’s supplements! I’ve tried various ones, and they are always of excellent quality! The price is nice, and the ingredients are great. I bought this for immune support during colds, and it does the job perfectly. The packaging is convenient, the lid closes tightly, and the capsules are standard size—easy to use.

Food Poisoning details

8 people found this helpful

I bought this supplement due to knee joint pain. Initially, self-massage helped briefly, but after taking this, my knees no longer bother me. I'm 34 years old and very pleased with the results.

Frozen Shoulder details

1 people found this helpful

This is my salvation. After pulling my shoulder at the water park, I had pain for four months. After three weeks of MSM, I realised my shoulder no longer hurt.

Knee Pain details

Toguchi A, Noguchi N, Kanno T, Yamada A. Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2023;15. doi:10.3390/nu15132995

Questionable

Based on 5 Researches

MSM improves mild knee pain

We explored the effects of methylsulfonylmethane (MSM) on knee pain through a well-structured randomized, double-blind, placebo-controlled trial.

Involving 88 healthy participants, the study compared the outcomes of those taking MSM against a placebo over a 12-week period.

Results showed that MSM significantly improved knee health and overall well-being according to the Japanese Knee Osteoarthritis Measure, with a notable difference in scores between the two groups.

This suggests that MSM could be a helpful option for those dealing with mild knee pain.

Remarkable results experienced

Most Useful Review

6 people found this helpful

Within a week, I was already noticing results. A month ago, I experienced significant knee pain while bending, and despite utilising pharmaceutical options, there was no improvement. After starting MSM from NOW on my sister’s recommendation (dosage: 2 tablets twice daily), my knee pain has completely vanished. I highly recommend this!

Liver Disease details

Enhanced liver strength

This is a good product. I take various supplements to keep my liver strong, and after using this, I feel that I've lost the dullness I previously experienced throughout the day.

Autoimmune Disorder details

KCNA2 autoimmunity diverse; immunotherapy beneficial

Arlt FA, Miske R, Machule ML, Broegger Christensen P, Mindorf S, et al. KCNA2 IgG autoimmunity in neuropsychiatric diseases. Brain Behav Immun. 2024;117:399. doi:10.1016/j.bbi.2024.01.220

We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.

7.5

Rheumatoid arthritis support

Most Useful Review

11 people found this helpful

This product has been a tremendous help for my joint issues, aiding in any inflammatory processes and overall body support. I had the recommendation from my sister, and it has proven to be of excellent quality. If you suffer from joint issues, such as rheumatoid arthritis, MSM is worth trying.

Candidiasis details

Excellent product! It’s a valuable supplement in combating Candidiasis. The quality is impressive, and the high dosage lets you avoid taking numerous capsules at once. I noticed the effects after a couple of weeks. This provides solid support for my joints while addressing any deficiencies.

Bloating details

Bloating as side effect

This is evidently a good and beneficial product, but I experienced one of the common side effects—bloating—within days of starting. Weeks after discontinuing, I'm still dealing with it, though my healthy diet has been beneficial.

Headache details