Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
The product is found useful for the following medical conditions
Reflux details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.8
8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
10
Relief from heartburn
Most Useful Review
My wife and I have tried a few other vitamin C brands that gave her terrible heartburn. We've been taking NOW vitamin C for some time now (on our second bottle), and she hasn't experienced any heartburn or acid reflux issues from it. The pills aren't tiny, but I find them easy to swallow. I can't recall when I last felt unwell, and I truly believe that taking vitamin C is the primary reason. I currently take two tablets daily (2,000 mg in total), one with breakfast and one with dinner. I usually increase to four when I've been around sick people.
Updated: Apr 2025
Chronic Cough details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
Dietary vitamin C reduces smoking-related cough
A survey of 4,300 young Norwegian adults examined whether dietary vitamin C intake relates to respiratory symptoms like cough and wheeze. Researchers estimated vitamin C consumption through questions about orange juice, oranges, potatoes, carrots, and tomatoes over the past year.
Among current smokers, those consuming more dietary vitamin C (395+ mg/week versus under 209 mg/week) showed reduced odds of morning cough and chronic cough. The protective effect was even stronger for ex-smokers experiencing wheeze. These benefits held true even after excluding people taking vitamin C supplements, suggesting the effect comes from food sources themselves.
The findings suggest that vitamin C's antioxidant properties may help counteract oxidative stress caused by smoking, potentially easing respiratory symptoms in smokers specifically.
Among current smokers, those consuming more dietary vitamin C (395+ mg/week versus under 209 mg/week) showed reduced odds of morning cough and chronic cough. The protective effect was even stronger for ex-smokers experiencing wheeze. These benefits held true even after excluding people taking vitamin C supplements, suggesting the effect comes from food sources themselves.
The findings suggest that vitamin C's antioxidant properties may help counteract oxidative stress caused by smoking, potentially easing respiratory symptoms in smokers specifically.
9
Eliminated symptoms
Most Useful Review
I purchased this vitamin C for my mother, as it's easier for her to take. She hasn't faced chronic cough or runny nose issues since starting this alongside vitamin D-3 and Omega 3.
Updated: Apr 2026
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
9
Reduced depression significantly
Most Useful Review
3 people found this helpful
Drinking this helped to reduce my depression and hair loss. In my experience, taking B vitamins, vitamin E, niacin, carnosine, and vitamin C together has a synergistic effect on depression, making it even more effective. For hair loss, combining vitamin E and niacin with vitamin C further lessened the problem. I didn't notice any difference in effectiveness compared to vitamin C without bioflavonoids.
Updated: Apr 2025
High Cholesterol details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 7 Reviews
8.6
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
10
Vital for health
Most Useful Review
3 people found this helpful
The formula with Rutin is very good. I take a high dosage, as recommended by Linus Pauling. This vitamin C is crucial for my survival since I became chemically sensitive after using Roundup. I find the capsules convenient compared to the hassle of dissolving crystals. I take 18,000mg daily alongside intravenous drips. It truly keeps me functioning, and without it, I believe my health would severely decline.
Updated: Mar 2026
Indigestion details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
No indigestion issues
Most Useful Review
Excellent! This effective vitamin C for adults aids in maintaining good health. The ingredients are straightforward and beneficial: vitamin C, bioflavonoids, and rutin. The latter two enhance the effectiveness of vitamin C. Each capsule contains 1000 mg, with a jar holding 100 capsules. Taking two capsules is sufficient for almost a season, as we don't always drink them daily—sometimes they are forgotten. Not only does this vitamin C support the immune system well, but it is also gentle on the stomach — though there are occasional indigestion, everything remains fine with this product. Therefore, I wholeheartedly recommend it!
Updated: Mar 2026
Pneumonia details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
Improved recovery speed
Most Useful Review
6 people found this helpful
After my dad became seriously ill with pneumonia, he was hospitalised. The doctor recommended vitamin D, C, and zinc, but we couldn't find the correct dosage locally, so I ordered it here. Within three days of taking the vitamins, my dad began to improve — his temperature fell, he regained his colour, and his breathing became easier. The doctor was astonished at his rapid recovery for his age and acknowledged that the vitamins certainly played a role.
Updated: Mar 2026
Tonsillitis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Prevented tonsillitis
Most Useful Review
A quick way to combat a virus, rating 10/10. During my illness, my seasonal cold often develops into acute tonsillitis, with all its consequences. This time, at the initial stages of the illness, I took a substantial dose—two tablets of 1000mg each. To my amazement, the temperature did not rise, and I did not experience a sore throat. Previously, this treatment helped me easily cope with an exacerbation of tonsillitis.
Updated: Mar 2026
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
9
Effective for iron deficiency
Most Useful Review
Great Vitamin C for adults! This isn't my first order; I take it to combat iron deficiency anemia and enhance iron absorption. I highly recommend it.
Updated: Mar 2026
Back Pain details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.3
USERS' SCORE
Good
Based on 2 Reviews
8.5
4
We conducted a year-long study to investigate the effects of vitamin C on postoperative pain and recovery after a specific type of spine surgery known as posterior lumbar interbody fusion (PLIF). In this randomized, placebo-controlled trial, we worked with 123 patients, dividing them into two groups: one receiving vitamin C and the other a placebo.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
9
Effective treatment noted
Most Useful Review
2 people found this helpful
During the epidemic, I avoided visiting the dentist. When I experienced bleeding gums or mouth sores, I took high doses of Vitamin C every hour or two. Within a day or two, the pain subsided significantly. For over three years, I’ve been taking around seven high-dose Vitamin C capsules daily and my overall health is excellent. I rarely need any medication and haven’t caught the flu.
Updated: Apr 2025
Bruise details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.2
USERS' SCORE
Good
Based on 7 Reviews
8.5
8
We explored how vitamin C can impact bruising, particularly in individuals experiencing a deficiency. The research highlighted a case involving an elderly woman who faced challenges such as weakness, easy bruising, and fatigue due to a lack of this vital nutrient.
After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.
This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.
This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
9
Strengthens blood vessels
Most Useful Review
2 people found this helpful
I take different vitamins of this brand. They are affordable and effective! I combined vitamin C with a routine of the same brand. I really liked the action of these vitamins. They work well together, and I've noticed the strengthening of blood vessels since I started taking them. The nosebleeds have ceased, and bruises on my legs no longer occur spontaneously. I recommend these vitamins, particularly for strengthening blood vessels.
Updated: Apr 2026
Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.5
9
Quick relief from cough
Most Useful Review
1 people found this helpful
Due to the pandemic, finding good vitamin C has become challenging, but this product is excellent. When I start to sneeze or cough, I take a capsule, and by morning, I feel fine again. This budget-friendly, high-quality product is wonderful, and I'm very grateful for it. Highly recommended!
Updated: Mar 2026
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 10 Reviews
8.5
8
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
9
Headache reduction
Most Useful Review
8 people found this helpful
I very often suffered from headaches and started taking a vitamin with bioflavonoids to strengthen my blood vessels. Initially, I drank it every three hours for a week, then switched to morning and evening doses. Surprisingly, my headaches have stopped, despite having previously taken numerous nootropics.
Updated: Apr 2026
Toothache details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Good for inflammation
Most Useful Review
This nutrient is my top choice. I took 3,000 mg of vitamin C daily to tackle all sorts of inflammation, including colds and toothaches. At times, I boosted my intake to 4,000 mg five times a day, and it worked exceptionally well!
Updated: Apr 2025
Whooping Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Effective relief
Most Useful Review
1 people found this helpful
Due to the pandemic, finding good vitamin C is quite challenging, but this product is fantastic. I started to sneeze and cough, so I took one capsule, and by morning, everything had cleared up. The quality is exceptional and budget-friendly. I am very grateful for this product—thank you. I highly recommend it.
Updated: Apr 2025
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 27 Reviews
8.4
9
Active lifestyle restored
Most Useful Review
8 people found this helpful
I'm thrilled with this product! Previously, I suffered from frequent colds, often with a red sore throat. I was terrified of catching a chill at night or even drinking something cool, but I’m delighted that these days are behind me! I drink vitamin C, alongside a complex with Echinacea, and occasionally some brandy, leading to significant improvement. I previously doubted long-term use, but seeing positive foreign reviews reassured me. Overall, my experience has been very positive.
Updated: Mar 2026
Attention Deficit Hyperactivity Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
Effective support
Most Useful Review
Прекрасно! This Now Foods product with vitamin C-1000 elicits extremely positive emotions. It provides invaluable support against mild colds. I highly recommend Now Foods products as their effectiveness is evident. I've tried other brands previously, but none had an effect. Although the capsules may seem large, I find them easy to take. Considering the package contains 100 capsules, the cost is reasonable—for more than three months' supply.
Updated: Mar 2026
Cold Sores details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 23 Reviews
8.4
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
9
Quick recovery
Most Useful Review
32 people found this helpful
This helps enormously with colds. I take it at the first signs, and it’s an excellent remedy!
Updated: Apr 2025
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Good
Based on 137 Reviews
8.4
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
9
Vitamins improve immunity
Most Useful Review
364 people found this helpful
Essential vitamin – I only order all my vitamins from here. I took this product upon recommendations and previously bought pure vitamins, but this one has a superior composition. From the start of winter until spring, this vitamin is a staple in our family. The winter season does affect our health, causing flu and runny noses.
Updated: Mar 2026
Herpes details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.4
9
We explored the effects of ascorbic acid and its derivatives on the replication of Herpes simplex virus type I using human muscle cancer cells.
The study revealed that a specific form of vitamin C, known as 2-O-glycoside of ascorbic acid, showed promising antiviral properties.
Interestingly, while this derivative can inhibit certain chemical reactions involving carbon-centered radicals, it does not impact reactions with oxygen-centered radicals.
However, despite these findings, the overall benefits of vitamin C treatment for herpes remain inconclusive.
The study revealed that a specific form of vitamin C, known as 2-O-glycoside of ascorbic acid, showed promising antiviral properties.
Interestingly, while this derivative can inhibit certain chemical reactions involving carbon-centered radicals, it does not impact reactions with oxygen-centered radicals.
However, despite these findings, the overall benefits of vitamin C treatment for herpes remain inconclusive.
9
Sunburn prevention
Most Useful Review
6 people found this helpful
Love! Saved from herpes! I take 2g of vitamin C daily and plan to increase to 3g by winter. In the past year, I haven't caught colds, despite regular stress and lack of sleep. It astonishingly stopped herpes one evening! After an unfortunate sunburn, I felt the onset of herpes on my lips, which I usually treat with acyclovir for over a week. However, after taking 4 capsules before bed, I woke up with no sign of it! I truly didn’t expect such results. I hope others benefit too! 🙏🏼⚠️
Updated: Mar 2026
Lung Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
We explored the effects of vitamin C on lung cancer, particularly its ability to inhibit pulmonary metastasis—meaning the spread of cancer to the lungs. Using an H22 pulmonary metastasis mouse model, we observed that vitamin C administration, both intraperitoneally and orally, showed promising results.
Through the research, we found that intraperitoneal injections of vitamin C led to an increase in crucial proteins like Nrf2 and HO-1, which are known to help combat cancer. This process resulted in increased cell death in cancer cells through DNA damage and apoptosis, mimicking the effects seen when using pro-oxidant treatments in cells lacking the p53 protein—a critical tumor suppressor.
Furthermore, oral vitamin C not only activated these protective pathways but also spurred the expression of p53 in healthy tumor cells, showcasing its potential as an antimetastatic agent. We noted that vitamin C reduced the proliferation and migration of lung cancer cells while being gentler on normal cells, suggesting a safer therapeutic profile.
Overall, this study highlights vitamin C's dual role in both bolstering the body's defenses against cancer and directly inhibiting the spread of lung cancer, paving the way for its consideration in clinical treatments for pulmonary metastasis.
Through the research, we found that intraperitoneal injections of vitamin C led to an increase in crucial proteins like Nrf2 and HO-1, which are known to help combat cancer. This process resulted in increased cell death in cancer cells through DNA damage and apoptosis, mimicking the effects seen when using pro-oxidant treatments in cells lacking the p53 protein—a critical tumor suppressor.
Furthermore, oral vitamin C not only activated these protective pathways but also spurred the expression of p53 in healthy tumor cells, showcasing its potential as an antimetastatic agent. We noted that vitamin C reduced the proliferation and migration of lung cancer cells while being gentler on normal cells, suggesting a safer therapeutic profile.
Overall, this study highlights vitamin C's dual role in both bolstering the body's defenses against cancer and directly inhibiting the spread of lung cancer, paving the way for its consideration in clinical treatments for pulmonary metastasis.
9
Effective against cancer
Most Useful Review
6 people found this helpful
Affordable and highly effective, particularly for lung cancer therapy. Vitamin C is ineffective without bioflavonoids, which many people overlook, and producers often exploit. However, these capsules have proven very beneficial in combating lung cancer, effectively disrupting cancer cells.
Updated: Apr 2025
Rosacea details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
We explored the effectiveness of Rutin Forte, a treatment that includes long-acting vitamin C along with zinc and selenium, in managing rosacea, particularly in its erythematous stage. Our study included 30 patients—20 women and 10 men, aged 25 to 50—who were divided into two groups. One group received standard treatments like antibiotics and topical therapies, while the other group received the same treatments along with Rutin Forte for 2 to 3 months.
Over a 12-month observation period, we observed significant improvements in the group that received Rutin Forte. This group showed a notable reduction in erythema, the redness associated with rosacea, and intriguingly, there were no relapses of the condition. Conversely, the standard treatment group experienced recurrences of rosacea by the third month of follow-up, and their reduction in erythema was less pronounced.
This indicates that Rutin Forte, likely due to the vitamin C it contains, might play a beneficial role in treating and preventing rosacea symptoms, particularly in stubborn cases. Overall, our findings suggest that incorporating vitamin C into rosacea treatment can be quite effective.
Over a 12-month observation period, we observed significant improvements in the group that received Rutin Forte. This group showed a notable reduction in erythema, the redness associated with rosacea, and intriguingly, there were no relapses of the condition. Conversely, the standard treatment group experienced recurrences of rosacea by the third month of follow-up, and their reduction in erythema was less pronounced.
This indicates that Rutin Forte, likely due to the vitamin C it contains, might play a beneficial role in treating and preventing rosacea symptoms, particularly in stubborn cases. Overall, our findings suggest that incorporating vitamin C into rosacea treatment can be quite effective.
9
Improved skin clarity
Most Useful Review
2 people found this helpful
Works effectively! It's a great product with high quality and efficiency. The large packaging lasted me over three months, making it very economical. I purchased it to maintain my health during autumn and winter, taking one capsule daily with no gastrointestinal side effects despite my high stomach acidity. I noticed significant benefits; my immunity improved, I stopped catching colds, and my nasal congestion vanished after weeks. Importantly, I observed a positive impact on my skin. I had red blood vessels on my nose from rosacea, but after a course of this vitamin C, my skin became clear and perfectly even. Excellent result!
Updated: Apr 2025
Sinusitis details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 5 Reviews
8.4
8
We explored the effects of L-ascorbate, commonly known as Vitamin C, on chloride transport in sinonasal epithelial tissues. This research is particularly significant as it addresses the common condition of chronic rhinosinusitis (CRS) and its potential link to the function of the cystic fibrosis transmembrane conductance regulator (CFTR) — a key chloride ion channel.
During our investigation, we utilized freshly excised sinonasal tissues from both normal individuals and patients suffering from CRS. The tissues were carefully prepared and tested to understand how L-ascorbate influenced chloride secretion. Our findings revealed that the application of L-ascorbate notably enhanced chloride secretion in these tissues.
This is important because optimal chloride transport is essential for maintaining healthy mucosal surfaces and effective mucociliary clearance. Therefore, since decreased chloride secretion could lead to the worsening of sinus conditions, L-ascorbate presents a promising avenue for therapeutic intervention in improving mucociliary clearance for those affected by chronic sinus issues.
During our investigation, we utilized freshly excised sinonasal tissues from both normal individuals and patients suffering from CRS. The tissues were carefully prepared and tested to understand how L-ascorbate influenced chloride secretion. Our findings revealed that the application of L-ascorbate notably enhanced chloride secretion in these tissues.
This is important because optimal chloride transport is essential for maintaining healthy mucosal surfaces and effective mucociliary clearance. Therefore, since decreased chloride secretion could lead to the worsening of sinus conditions, L-ascorbate presents a promising avenue for therapeutic intervention in improving mucociliary clearance for those affected by chronic sinus issues.
9
Sinusitis-free life
Most Useful Review
1 people found this helpful
Very effective for sinusitis, I had it on and off for five years. I used to visit my doctor whenever my allergies flared; however, since I started taking this supplement—recommended by a friend—I've not had to return to the doctor. It's been two years now, and I'm free from sinusitis.
Updated: Apr 2026
Sore Throat details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 19 Reviews
8.4
9
Active lifestyle restored
Most Useful Review
8 people found this helpful
Excellent! I am thoroughly impressed. The jar is substantial, and I’ve calculated how long it should last as I consume it over several months. I used to be sick with colds frequently. A red sore throat was my constant companion. I was often worried about going out in the cold or consuming anything too cool. I’m delighted this is now a thing of the past! I take this vitamin C alongside Echinacea, and the difference in my health has been remarkable; I now live more actively without fear!
Updated: Apr 2025
Acne Rosacea details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Clear skin improvement
Most Useful Review
2 people found this helpful
Works effectively 👌🏽 Great product! Both quality and efficacy are high! The large packaging lasted me more than three months, making it very cost-effective. I purchased it to maintain my health during the autumn-winter period, taking one capsule daily. I experienced no gastrointestinal side effects, even with my increased stomach acidity. I noticed a significant improvement in my health; my immunity strengthened, I stopped catching colds, and the nasal congestion that troubled me for weeks disappeared. Additionally, there was a positive effect on my skin, as I had red blood vessels in the nose area due to acne rosacea. After a course of this vitamin C, my skin became clear and perfectly smooth. Excellent result!
Updated: Apr 2025
Arthritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.3
7
We explored the role of vitamin C in addressing arthritis symptoms, particularly its effect on joint inflammation. Vitamin C is known for its antioxidant properties, and we found that it plays a crucial role in collagen synthesis. This feature is important as collagen forms the structural basis of our joints.
What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.
However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.
Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively.
What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.
However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.
Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively.
9
Helpful for inflammation
Most Useful Review
I have been a loyal consumer of Thorne Pure Ascorbic Acid, but when they reduced the capsules, I searched for a replacement. I decided to try "NOW Foods, C-1000 with Bioflavonoids" due to its safe, vegetable-sourced ingredients. Although I don't have arthritis, my mother does, and this supplement has been helpful for her inflammation and pain. I manage my allergies effectively with this vitamin C, reducing my need for OTC allergy medications. These capsules are of acceptable size and are gentle on my stomach. I highly recommend giving it a try!
Updated: Mar 2026
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
7.5
Boosts immunity
Most Useful Review
Helps not to get sick! I ordered it a second time; my whole family uses it. In spring and autumn, when we sense a cold starting, we quickly take two tablets a day. It boosts our immune systems and helps us avoid illness.
Updated: Mar 2026
Bacterial Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 14 Reviews
8.3
9
Fights infections well
Most Useful Review
3 people found this helpful
If you seek a quality vitamin C, look no further. The large packaging lasts well for two adults. My wife and I noticed improved energy and reduced fatigue shortly after we started taking it. She's convinced that high doses of vitamin C are excellent against "bacterial infection". Remarkably, we didn’t fall ill that spring. I highly recommend this product!
Updated: Mar 2026
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
7.5
Pain relief achieved
Most Useful Review
2 people found this helpful
During the epidemic, I did not visit the dentist. When I experienced bleeding gums or mouth sores, I took high doses of vitamin C every couple of hours. Within one or two days, the pain subsided. I have been taking around seven capsules of high-dose vitamin C daily for over three years, and I feel well. I do not require any other medication and have not had the flu.
Updated: Apr 2026
Stroke details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
We explored how vitamin C stimulation affects the recovery of stroke patients suffering from dysphagia, a condition that makes swallowing difficult. In a carefully designed study involving 120 stroke patients, we divided them into two groups: one received traditional swallowing training, while the other group was given vitamin C stimulation alongside their training.
Our findings highlighted that those who received vitamin C showed marked improvements in their ability to swallow, as reflected in assessments such as the water swallow test and video fluoroscopic swallowing study. Additionally, we observed enhancements in their nutritional status and immune function, measured by indices like serum albumin and immunoglobulins.
Overall, it seems that vitamin C isn’t just a vitamin; it may play a vital role in helping stroke patients recover more effectively from dysphagia. This evidence supports using vitamin C as a beneficial component in stroke rehabilitation plans.
Our findings highlighted that those who received vitamin C showed marked improvements in their ability to swallow, as reflected in assessments such as the water swallow test and video fluoroscopic swallowing study. Additionally, we observed enhancements in their nutritional status and immune function, measured by indices like serum albumin and immunoglobulins.
Overall, it seems that vitamin C isn’t just a vitamin; it may play a vital role in helping stroke patients recover more effectively from dysphagia. This evidence supports using vitamin C as a beneficial component in stroke rehabilitation plans.
9
Protects against strokes
Most Useful Review
Excellent! Vitamin C is vital for the body’s normal functioning, particularly in children. Ascorbic acid reduces the risk of chronic diseases and offers protection against strokes and heart attacks; it heals wounds, strengthens bones, and enhances brain function, among other benefits. This supplement includes bioflavonoids that assist in the absorption of vitamin C. I highly recommend it.
Updated: Mar 2026
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 5 Reviews
8.2
8
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9
Manages allergies well
Most Useful Review
I have been using this product for many years now, and it effectively keeps my allergies at bay while supporting my overall well-being!
Updated: Mar 2026
Celiac details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.2
9
Enhanced energy levels
Most Useful Review
This vitamin C has become my go-to dietary supplement for immunity support. After a few weeks of use, I’ve experienced a notable improvement in my well-being, particularly during the cold season. As a powerful antioxidant, it’s effectively absorbed due to the added bioflavonoids, enhancing its efficacy. This product is free from GMOs, gluten, dairy, and soy, making it suitable for those with dietary restrictions. It also aids collagen levels, benefiting skin and joint health. One capsule a day suffices, and the airtight packaging needs no special storage. I now feel far more energetic and resilient against stress, so I highly recommend this vitamin.
Updated: Apr 2025
Nausea details
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
2
USERS' SCORE
Good
Based on 4 Reviews
8.2
2
Vitamin C ineffective against nausea
We explored the effects of vitamin C as a treatment for nausea and vomiting in pregnancy, also known as emesis gravidarum. Our study involved 111 participants, who were given either vitamin C-containing chewing gum, a placebo, or no treatment at all. We monitored them over two follow-up visits in early pregnancy to assess their symptoms.
While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.
Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.
Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.
Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.
Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
10
Prevents nausea
Most Useful Review
Good product that I consume in winter to prevent vitamin deficiency. It does not induce nausea or allergies.
Updated: Mar 2026
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.1
USERS' SCORE
Good
Based on 2 Reviews
8.2
8
We explored the connection between vitamin C levels and bone mineral density (BMD) in individuals with diabetes. By examining a group of 74 diabetic patients alongside 26 age-matched non-diabetic controls, we focused on how vitamin C intake could potentially influence bone health. Our goal was to see if higher vitamin C levels were associated with improved BMD and whether this effect might be related to decreases in certain inflammatory markers like VCAM-1 and adiponectin.
The results were quite promising. We observed a positive link between circulating levels of vitamin C and BMD, suggesting that higher vitamin C might indeed contribute to healthier bones. Notably, we found that this beneficial effect was closely tied to lower levels of inflammatory markers in the blood. This indicates that vitamin C might help not just in improving BMD but also in lowering inflammation, which can be particularly valuable for those living with diabetes.
Overall, our findings highlight the importance of maintaining adequate vitamin C levels as a potential strategy to reduce the risk of osteoporosis in individuals with diabetes. Incorporating vitamin C in the diet could be a simple yet effective way to support bone health while also combatting underlying inflammation.
The results were quite promising. We observed a positive link between circulating levels of vitamin C and BMD, suggesting that higher vitamin C might indeed contribute to healthier bones. Notably, we found that this beneficial effect was closely tied to lower levels of inflammatory markers in the blood. This indicates that vitamin C might help not just in improving BMD but also in lowering inflammation, which can be particularly valuable for those living with diabetes.
Overall, our findings highlight the importance of maintaining adequate vitamin C levels as a potential strategy to reduce the risk of osteoporosis in individuals with diabetes. Incorporating vitamin C in the diet could be a simple yet effective way to support bone health while also combatting underlying inflammation.
7.5
Calcium absorption
Most Useful Review
Vitamin C aids calcium absorption, making the combination of ascorbic acid and calcium effective for preventing osteoporosis. It acts as a cofactor for collagen synthesis, which benefits connective tissue and promotes healing, as well as supporting cardiovascular health. This high-quality supplement, at a dose of 1000 mg, is excellent for adults wanting to boost their immunity; I highly recommend it.
Updated: Apr 2025
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.2
7.5
Reduced facial rashes
Most Useful Review
Excellent vitamins! My immunity has increased, and there have been fewer rashes on my face, leading to improved mood and overall condition!
Updated: Apr 2025
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.2
9
Vitamin C improves sleep apnea endothelial function
We evaluated how vitamin C might improve endothelial function in patients with obstructive sleep apnea (OSA). In our study, we compared 10 individuals with untreated OSA to 10 matched control subjects without sleep issues. We measured how well blood vessels reacted to increased blood flow, known as flow-mediated dilation (FMD), using ultrasound before and after administering vitamin C.
Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.
These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.
These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
7.5
Significant improvement
Most Useful Review
MSM and vitamin C make a fantastic combination. This nutritional supplement was recommended by our good friend Bashar. Within less than a week of use, I have seen major improvements in my mental and physical strength, as well as my sleep quality. I would happily purchase this product again!
Updated: Mar 2026
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.2
9
No swelling
Most Useful Review
Fantastic vitamin C! It contains bioflavonoids, which enhance its absorption. After taking it, I experience no swelling or heartburn and feel more energised. Highly recommended.
Updated: Apr 2025
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.6
USERS' SCORE
Good
Based on 19 Reviews
8.1
9
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
9
Pimples eliminated
Most Useful Review
4 people found this helpful
I also use Vitamin C powder from another manufacturer, yet I have introduced a capsule type as taking 5000 to 10000 mg of powder alone is complex. I've heard that excess can cause diarrhoea, but perhaps my body has adjusted since the diarrhoea has ceased. My urine appears yellow; if it doesn't, it's easy to see that I am lacking, making it visually clear. It doesn’t upset my stomach, and my skin is completely free of pimples; I haven't tried anything new, so I am very pleased, and it's entirely unrelated to the popularity of Corona. The cost-performance ratio is favourable too!
Updated: Apr 2026
Blood Clot details
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 4 Reviews
8.1
9
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
9
Stopped medication
Most Useful Review
Despite not noticing changes from other supplements over two years, I managed to discontinue my blood pressure medication after taking this.
Updated: Mar 2026
Cancer details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 3 Reviews
8.1
9
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9
Essential for therapy
Most Useful Review
6 people found this helpful
Vitamin C is remarkably effective, especially in cancer therapy. Many people underestimate the importance of bioflavonoids which are essential for its effectiveness. These capsules have proven beneficial, showing significant efficacy in combating cancer cells.
Updated: Mar 2026
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 6 Reviews
8.1
7
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
8
Replenishes energy
Most Useful Review
1 people found this helpful
This vitamin C product has alleviated symptoms of deficiency for me, such as bleeding gums and fatigue. It has greatly improved my skin's condition and energy levels, benefiting my chronic fatigue syndrome.
Updated: Mar 2026
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.1
9
Helpful for sleep
Most Useful Review
Great bowel cleanse. Very good delivery, and after long waits, I saw the xhs sisters sharing stock while I was fishing in the beautiful morning. I quickly placed my order, finding it to be very cost-effective. Presently, I believe it is quite useful for me; I've noted improvements in my sleep.
Updated: Mar 2026
Bloating details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8
7
We aimed to explore how different measures of vitamin C might influence premenstrual symptoms, particularly bloating. In this study, we analyzed data from 555 women aged 20 to 29 years who reported on various symptoms associated with their menstrual cycles. We looked at their dietary intake of vitamin C, measured serum ascorbic acid levels, and assessed genetic factors through DNA testing.
Our findings suggest that higher vitamin C status is linked to increased appetite changes and symptoms like bloating and swelling during the premenstrual phase. While we observed associations between vitamin C levels and these symptoms, it's important to note that our study didn't isolate the effect of vitamin C from other dietary influences. Therefore, while there's a connection between vitamin C and bloating, we cannot conclusively say that vitamin C alone is definitive in relief.
Overall, this research opens the door to understanding how nutrition, particularly vitamin C intake, may shape our experiences with premenstrual symptoms. However, it also highlights the complexity of diet's role in our health.
Our findings suggest that higher vitamin C status is linked to increased appetite changes and symptoms like bloating and swelling during the premenstrual phase. While we observed associations between vitamin C levels and these symptoms, it's important to note that our study didn't isolate the effect of vitamin C from other dietary influences. Therefore, while there's a connection between vitamin C and bloating, we cannot conclusively say that vitamin C alone is definitive in relief.
Overall, this research opens the door to understanding how nutrition, particularly vitamin C intake, may shape our experiences with premenstrual symptoms. However, it also highlights the complexity of diet's role in our health.
9
No bloating issues
Most Useful Review
The best part is the substantial content. High doses of vitamin C can lead to bloating, but this NOW Foods product does not seem to cause that for me.
Updated: Mar 2026
Cardiovascular Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8
7
Vitamin C enhances NK cell proliferation
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
7.5
Immunity improvement
Most Useful Review
1 people found this helpful
This excellent high-dose vitamin C is essential for immunity against colds. I took it at the first signs of a cold, and it helped clear the infection quickly. During a more severe cold, it alleviated symptoms and shortened the illness duration. Though the capsules are large and can upset my sensitive stomach, this brand is preferable to pharmacy options. Sharing the capsules also helped my brother recover from his cold.
Updated: Apr 2025
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 856 Reviews
8
7
Effectiveness of Vitamin C on Colds
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
10
Helps with cold
Most Useful Review
296 people found this helpful
The quality is excellent. The best antioxidant, it supports immunity. For colds, it works effectively with zinc for a quick recovery.
Updated: Mar 2026
Adrenal Gland Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
7.5
Supports overall well-being
Most Useful Review
1 people found this helpful
Vitamin C is important not only during colds but also for general well-being. It is essential in collagen formation and is not produced by the body, so must be ingested externally. Vitamin C improves insulin resistance, supports the adrenal glands, and is vital during stress, as the body’s needs increase. A lack of vitamin C is linked to numerous health issues. Therefore, it’s crucial to replenish it, especially during periods of illness or stress.
Updated: Apr 2025
Constipation details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.8
8
We conducted a fully decentralized clinical trial to explore the effects of vitamin C on constipation symptoms. Participants who experienced functional constipation were randomly assigned to receive either Lactobacillus with vitamin C or vitamin C alone over a two-week treatment period. The study allowed us to gather data remotely, which is quite innovative and accessible.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
9
Stomach relief
Most Useful Review
The surface has a slightly salty taste from the capsule's ingredients. The thick, large shape makes it hard to swallow. I drink more than recommended, which sometimes feels like it's stuck in my chest, so I take care to drink plenty of water with it. Initially taken for physical condition management, it has led to good stomach and intestinal health. The best part is my constipation has resolved.
Updated: Mar 2026
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.8
9.5
We conducted a double-blind trial involving sixteen individuals with chronic foot ulcers to see how vitamin C impacts their healing. Half of the participants received 500 mg of vitamin C, while the others got a placebo.
After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.
Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.
After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.
Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.
9
No more ulcers
Most Useful Review
I no longer have mouth ulcers.
Updated: Mar 2026
Gastritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.4
8
We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
9
Eliminated discomfort
Most Useful Review
Vitamin C with bioflavonoids is essential for every cell in the body. I take one capsule daily after meals for a month. My overall health has improved; I feel more energised. Remarkably, the stomach discomfort from gastritis vanished. Initially, I hesitated to take vitamin C due to my stomach inflammation, but I took the plunge and my worries were unfounded. My stomach expressed gratitude as the cramps, belching, and heartburn ceased. I continue to use this vitamin and recommend it to my acquaintances.
Updated: Mar 2026
Kidney Stones details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.9
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.1
4
We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
4
Negative impact on kidneys
Most Useful Review
The dosage of vitamin C is excessive and negatively impacts my kidneys. I will not continue with such large doses, although everyone manages their own health differently.
Updated: Mar 2026
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 5 Reviews
7
9
No bone pain
Most Useful Review
2 people found this helpful
During the epidemic, I avoided the dentist. When dealing with bleeding gums or mouth sores, I took a high dose of vitamin C, which alleviated my pain within a day or two. For over three years, I've taken about seven high-dose vitamin C capsules daily. My health has been excellent—I haven't taken any other medication and haven't caught the flu.
Updated: Apr 2025
Chest Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.3
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.5
9
We explored the effects of vitamin C on chest pain in chronic smokers experiencing endothelial dysfunction. In our study, 31 patients, who were undergoing diagnostic catheterization without significant coronary artery issues, participated in a controlled trial. They were given either an IV infusion of 3 grams of ascorbic acid (vitamin C) or a placebo saline solution before undergoing a cold pressor test to assess their coronary artery response.
The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.
This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.
The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.
This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.
9
Improves chest symptoms
Most Useful Review
3 people found this helpful
The capsules are large and taste sour. I took them after breakfast with some water to avoid pain, unlike when I took them on an empty stomach. The quantity is excellent, and they wonderfully alleviate my chest pain. After I received the Covid vaccine and felt unwell, this product helped with the fatigue lasting only one day. Additionally, my skin improved significantly, with red acne spots beginning to fade. I recommend it; just remember to keep it in the fridge.
Updated: Apr 2025
Heartburn details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 11 Reviews
6.5
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9
Heartburn-free vitamin
Most Useful Review
1 people found this helpful
I added this vitamin to my diet to bolster my immunity. I have not experienced any heartburn or runny nose while taking it. I'm satisfied with the product and will continue using it.
Updated: Mar 2026
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