Probiotics
9
Saccharomyces effectively treats anemia
Production of iron-enriched yeast and it's application in the treatment of iron-deficiency anemia.
Most Relevant Research
We aimed to explore whether Saccharomyces cerevisiae, enriched with iron, could serve as a beneficial treatment for iron-deficiency anemia (IDA) in mice. Our study involved dividing 60 mice into groups that received various forms of iron supplements, including the enriched yeast strain.
Remarkably, those treated with the iron-enriched yeast showed significant recovery. Their weights and blood parameters returned to normal, and levels of key antioxidants in their blood improved. This suggests that strain no. F8, which thrives in iron-rich conditions, could be a promising avenue for developing new organic iron supplements.
Remarkably, those treated with the iron-enriched yeast showed significant recovery. Their weights and blood parameters returned to normal, and levels of key antioxidants in their blood improved. This suggests that strain no. F8, which thrives in iron-rich conditions, could be a promising avenue for developing new organic iron supplements.
9.5
Convenient anaemia solution
Most Useful Review
I have a positive impression of these vitamins. The vitamin B12 spray format is convenient for children, avoiding injections or pills. As someone with low hemoglobin and a restricted diet, I find these vitamins helpful. No side effects, and after a month, my hair stopped falling out, and chronic fatigue disappeared.
Multivitamins
9.5
No side effects
Most Useful Review
I ordered this complex for myself and my parents due to iron deficiency anaemia. The doctor recommended B-group vitamins due to high homocysteine levels, which pose risks for cardiovascular health. Many pharmaceutical options include harmful additives, but this bioactive complex has everything required. I feel fantastic and noticed no side effects, while the price-to-quality ratio is excellent. To aid absorption, it’s also important to take magnesium and vitamin C.
9.5
Promotes blood health
Most Useful Review
I consistently order this quality product as it contains B12 in the methylcobalamin form, which is optimal for metabolism, unlike cyanocobalamin. Its mild taste is acceptable and significantly benefits the nervous system, particularly for the elderly and those with anaemia, as B12 helps maintain blood levels. The supply is sufficient for a month if I take two pills daily or two tablets if I get enough B vitamins from food. I strongly recommend purchasing it.
Vitamin B12
9
Pernicious anemia linked to B12
Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report.
Most Relevant Research
We explored the intriguing case of a 51-year-old man in Western Uganda who experienced lower limb weakness linked to pernicious anemia, a condition caused by vitamin B12 deficiency. His journey illustrates the importance of recognizing the signs of this often-overlooked autoimmune disease.
Initially presenting with macrocytic anemia, our patient had a history of similar symptoms seven years prior, which were treated for vitamin B12 deficiency. This time, additional tests confirmed that pernicious anemia was at play, allowing for targeted treatment.
After starting parenteral methylcobalamin therapy, he showed significant improvement in his symptoms. This case underscores that vitamin B12 is crucial not just for red blood cell production but also for neurological health, emphasizing the need for increased awareness and diagnosis of vitamin B12 deficiencies in resource-limited settings.
Initially presenting with macrocytic anemia, our patient had a history of similar symptoms seven years prior, which were treated for vitamin B12 deficiency. This time, additional tests confirmed that pernicious anemia was at play, allowing for targeted treatment.
After starting parenteral methylcobalamin therapy, he showed significant improvement in his symptoms. This case underscores that vitamin B12 is crucial not just for red blood cell production but also for neurological health, emphasizing the need for increased awareness and diagnosis of vitamin B12 deficiencies in resource-limited settings.
8.8
Improved vitamin levels
Most Useful Review
I had very low vitamin B-12, around 150 units, which caused me to feel unwell and showed signs of anemia. After taking this supplement, I raised my B-12 to 275 units. I appreciate that methylcobalamin is noted as a more natural form. This product has been very helpful for me.
Lactoferrin
9
Pediatric anemia treatment evaluation
Oral lactoferrin as a treatment of pediatrics' anemia resulted from chronic kidney diseases: a randomized controlled trial.
Most Relevant Research
We explored an important question regarding anemia management in children with chronic kidney disease (CKD). In a randomized clinical trial, we compared the effectiveness of oral lactoferrin and intravenous iron dextran in treating anemia related to CKD in pediatrics.
The study involved 60 children who were divided into two groups: one received 100 mg of oral lactoferrin daily for three months, while the other group was treated with IV iron dextran three times a week. After the treatment period, we observed significant changes in several blood parameters among those taking oral lactoferrin, specifically in hemoglobin, red blood cells, and various other indicators related to anemia.
However, while both treatments proved effective, we found no significant differences between the two groups overall in improving anemia symptoms after three months. Ultimately, while oral lactoferrin showed promising results, it did not outperform IV iron dextran to a degree that would change treatment choices.
The study involved 60 children who were divided into two groups: one received 100 mg of oral lactoferrin daily for three months, while the other group was treated with IV iron dextran three times a week. After the treatment period, we observed significant changes in several blood parameters among those taking oral lactoferrin, specifically in hemoglobin, red blood cells, and various other indicators related to anemia.
However, while both treatments proved effective, we found no significant differences between the two groups overall in improving anemia symptoms after three months. Ultimately, while oral lactoferrin showed promising results, it did not outperform IV iron dextran to a degree that would change treatment choices.
9.5
Ferritin has risen
Most Useful Review
I am truly grateful that I discovered Lactoferrin! I have chronic anaemia and struggled to increase my ferritin levels. After ceasing iron supplements, my ferritin dropped to 3. Thankfully, Lactoferrin raised it to 56! My health has greatly improved; my depression has lifted, my sleep quality has enhanced, and I've gained warmth in my limbs. This supplement has remarkable properties against various viruses and aids in cell oxygenation, boosting stamina and recovery from illness.
Vitamin Bs
9.5
Energy boost
Most Useful Review
I’m pleased with this complex, as it truly provides energy. On a stressful day, I doubled my intake and felt revitalised. The whole family uses it, and we all appreciate the wonderful results, especially regarding my husband's and my assistance in treating our anemia.
9.5
Improved vitamin levels
Most Useful Review
An excellent B vitamin complex. After being diagnosed with anaemia, I took one tablet daily for six months. My vitamin levels have returned to normal, and my hair and nails are growing remarkably well. There were no side effects, just bright yellow urine, but who else pays attention to that?
8.8
Improved hemoglobin levels
Most Useful Review
The syrup is palatable, does not cause constipation, and increases haemoglobin within a month. I noticed latent anaemia in my child, indicated by blood tests showing low erythrocyte levels and high platelets. I often see this in children whose mothers report poor sleep and fatigue. Monitoring every six months is essential, with an individual dosage usually between 10-15 mg.
8.8
Increased haemoglobin
Most Useful Review
The baby iron syrup can be given from two months alongside a multivitamin complex. It's pleasant, does not lead to constipation, and effectively raises haemoglobin within a month. I often notice anaemia in children with poor sleep and low appetite. Regular monitoring is important, and the typical dosage ranges from 15 mg.
Ginkgo
8.8
Sleep improvement
Most Useful Review
The strength of these capsules has greatly improved my blood circulation and energy. The pain in my veins ceased, and my hand numbness reduced significantly. I now fall asleep within 45 minutes, whereas I previously struggled for two hours due to insomnia. Ginkgo pills are essential for managing diabetes and hypertension, plus they're beneficial for the elderly and anyone suffering from anemia.
8.8
Enhanced sleep
Most Useful Review
These capsules are excellent! They have improved my blood circulation and energy immensely, making the pain in my veins disappear. Also, my hand numbness has reduced. I can now sleep within 45 minutes instead of two hours due to my insomnia. I highly recommend Ginkgo for those with diabetes and hypertension, as well as for the elderly and those with anemia.
Vitamin E
9.5
Supports oxygenation
Most Useful Review
I constantly drink Vitamin E as it’s essential for supplying oxygen to the internal organs, especially in less-than-ideal environments. Factors like smoking and anemia can deprive organs of oxygen. Vitamin E compensates for this deficiency. I repeatedly order this product.
8
Antioxidant benefits
Most Useful Review
Vitamin E is an excellent antioxidant with anti-inflammatory, antithrombotic, and vasodilating effects, making it a superb cardioprotector. As it’s vital for the body, a deficiency can lead to symptoms including neuropathy and anemia.
Vitamin B6
8
Effect of B6 on anemia explored
A novel and apparent missense variant associated with congenital sideroblastic anemia.
Most Relevant Research
We explored the case of a 10-year-old boy diagnosed with congenital sideroblastic anemia (CSA). This condition can lead to severe anemia due to the body’s ineffective production of red blood cells. As part of the investigation, we performed various blood tests and conducted gene mutation analysis to identify any underlying causes.
We identified a novel genetic variant (c.1102C > T:p. Arg368Trp) that seemed to play a significant role in this boy's anemia. Notably, the treatment regimen included vitamin B6, known to help in certain cases of sideroblastic anemia, along with another medication called deferasirox. After six months of treatment, the patient saw significant improvement; his hemoglobin levels rose significantly, and iron overload was managed effectively.
While our findings suggest that vitamin B6 can be beneficial for some patients with CSA, it was combined with deferasirox in this instance. Consequently, isolating the exact impact of vitamin B6 on the anemia proves challenging. Nevertheless, this case highlights the importance of mutational analysis and tailored treatments in managing inherited blood disorders.
We identified a novel genetic variant (c.1102C > T:p. Arg368Trp) that seemed to play a significant role in this boy's anemia. Notably, the treatment regimen included vitamin B6, known to help in certain cases of sideroblastic anemia, along with another medication called deferasirox. After six months of treatment, the patient saw significant improvement; his hemoglobin levels rose significantly, and iron overload was managed effectively.
While our findings suggest that vitamin B6 can be beneficial for some patients with CSA, it was combined with deferasirox in this instance. Consequently, isolating the exact impact of vitamin B6 on the anemia proves challenging. Nevertheless, this case highlights the importance of mutational analysis and tailored treatments in managing inherited blood disorders.
8.8
Supports energy production
Most Useful Review
Excellent composition! I take these vitamins daily, finding them delicious and effective against anaemia. They support energy and biochemical processes. I highly recommend them, especially since they're hard to find elsewhere.
Folate
7
Factors influencing supplement adherence
Determinants of compliance with iron-folic acid supplementation among pregnant mothers in Bule Hora district, Southern Ethiopia: unmatched case-control study.
Most Relevant Research
We conducted an unmatched case-control study in Bule Hora district, Southern Ethiopia, aiming to understand what factors affect pregnant women’s compliance with iron and folic acid supplementation. This is crucial because these supplements are recommended to help prevent anemia during pregnancy, a common issue in many areas including Ethiopia.
Our research included 115 cases of women who adhered to supplementation and 230 controls who did not. We focused on various influencers such as health care interactions, knowledge about anemia, and support from partners. Interestingly, we found that the likelihood of compliance increased with factors like being a first-time mother, attending antenatal care at least four times, receiving support from husbands, and having solid knowledge about anemia.
From our findings, it’s clear that enhancing support from partners and improving the overall frequency of health care contacts can significantly boost compliance with iron and folic acid supplementation. Sharing information about anemia with expectant mothers also plays a vital role in increasing adherence to these important health recommendations.
Our research included 115 cases of women who adhered to supplementation and 230 controls who did not. We focused on various influencers such as health care interactions, knowledge about anemia, and support from partners. Interestingly, we found that the likelihood of compliance increased with factors like being a first-time mother, attending antenatal care at least four times, receiving support from husbands, and having solid knowledge about anemia.
From our findings, it’s clear that enhancing support from partners and improving the overall frequency of health care contacts can significantly boost compliance with iron and folic acid supplementation. Sharing information about anemia with expectant mothers also plays a vital role in increasing adherence to these important health recommendations.
9.5
Visible results
Most Useful Review
Bioactive form! This means that vitamins are well absorbed, even by those with malabsorption issues. It helps maintain red blood cell production within the normal range. I use it alongside iron for my anaemia. The results were visible within a month. The capsules are small and easy to swallow, even for children. I recommend it.
Protein
8
Romiplostim shows promise in AA
[Efficacy and safety of romiplostim in aplastic anemia refractory or intolerant to immunosuppressive therapy with eltrombopag].
Most Relevant Research
In our exploration of how protein treatments can improve anemia, we focused on the impact of romiplostim, a thrombopoietin receptor agonist, on patients suffering from aplastic anemia (AA) who were either refractory to or intolerant of eltrombopag (EPAG). We studied a group of 18 patients, most of whom had severe AA, who transitioned from EPAG to romiplostim for at least three months.
Remarkably, 72% of these patients responded positively to romiplostim, with many showing improvement in their blood cell counts within the first three months. Of these, half demonstrated a trilineage response, meaning their blood counts improved across multiple cell types. However, we noticed that those who initiated romiplostim a significant time after their initial AA diagnosis tended to struggle to respond effectively.
In instances where treatment with romiplostim was interrupted, we observed that some patients relapsed into thrombocytopenia, suggesting that romiplostim plays a critical role in maintaining blood counts. Overall, our findings indicate that romiplostim can be a valuable option for patients who do not benefit from other treatments, bringing renewed hope in the management of this challenging condition.
Remarkably, 72% of these patients responded positively to romiplostim, with many showing improvement in their blood cell counts within the first three months. Of these, half demonstrated a trilineage response, meaning their blood counts improved across multiple cell types. However, we noticed that those who initiated romiplostim a significant time after their initial AA diagnosis tended to struggle to respond effectively.
In instances where treatment with romiplostim was interrupted, we observed that some patients relapsed into thrombocytopenia, suggesting that romiplostim plays a critical role in maintaining blood counts. Overall, our findings indicate that romiplostim can be a valuable option for patients who do not benefit from other treatments, bringing renewed hope in the management of this challenging condition.
9.5
Helps iron deficiency
Most Useful Review
Amazing! It’s excellent for those who suffer from anaemia and iron deficiency. I always order it.
Vitamin C
7
Vitamin C enhances iron absorption
Vitamin C-Rich Guava Consumed with Mungbean Dal Reduces Anemia and Increases Hemoglobin but not Iron Stores: A Randomized Controlled Trial of Food-to-Food Fortification in Indian Children.
Most Relevant Research
We conducted a study to explore the impact of adding vitamin C-rich guava to a traditional meal of mungbean dal on children’s anemia in rural India. Our randomized controlled trial involved 200 school-aged children, many of whom were found to be anemic and iron-deficient. We aimed to see if this simple addition could improve their hemoglobin levels and overall iron status.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
9.5
Increased iron levels
Most Useful Review
I purchased this to take alongside iron supplements as recommended by a professor, due to my lifelong struggle with anemia. Indeed, this method effectively and rapidly raises iron levels in the blood. Vitamin C helps oxidise iron for better absorption in the body. There’s plenty of powder in the jar to last a long time, and I sometimes add it to tea for a bit of tang. A quality product!
Iron
8
Ferric Carboxymaltose Replaces Iron Sucrose
A cost-effective innovation in anaemia management for paediatric patients with haemodialysis-dependent chronic kidney disease.
Most Relevant Research
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
9.5
Saved from anemia
Most Useful Review
Solgar's iron supplement was a lifesaver for my severe anemia. I was barely able to function, feeling exhausted and memory impaired. After months of taking various iron pills, I finally overcame anemia. Doctors advised me to continue taking iron after each menstrual cycle due to my significant blood loss. I can't pinpoint any drawbacks to this supplement; it has solely beneficial effects.
Spirulina
9.5
Positive changes noted
Most Useful Review
I started giving my 8-month-old daughter spirulina for her anaemia upon my nutritionist's advice. Within two weeks, I've noticed positive changes in her energy and activity levels, although I dislike the taste.
9.5
Eliminates anaemia
Most Useful Review
Spirulina is remarkable for addressing anaemia thanks to its rich protein and iron content. It also supports brain function and detoxification, boosting overall health.
Fish Oil
8
Omega-3 enhances anemia treatment
Comparative effectiveness of adding omega-3 and Manuka honey combination to conventional therapy in preventing and treating oxidative stress in pediatric β-thalassemia major - a randomized clinical trial.
Most Relevant Research
We explored the effectiveness of adding omega-3 fish oil, specifically its components eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), along with Manuka honey, to conventional therapies in treating oxidative stress in children with β-thalassemia major. In this study, 165 pediatric patients were involved in a randomized, double-blind trial. They were divided into three groups: one received a combination of omega-3 and Manuka honey, while another group got just Manuka honey, and a third group followed standard treatment alone.
Throughout the ten-month study period, we measured various markers of oxidative stress and overall health in these children. Our findings revealed that the combination of omega-3 and Manuka honey showed more effectiveness in managing oxidative stress than either Manuka honey alone or the conventional treatment. This suggests that integrating omega-3 into their treatment plan could offer better outcomes for managing the health challenges associated with β-thalassemia.
Ultimately, our research highlights the potential role of omega-3 as a beneficial component in the treatment of anemia related to oxidative stress in pediatric patients. By addressing both oxidative stress and iron overload, we hope this approach leads to improved management strategies for young individuals dealing with this inherited condition.
Throughout the ten-month study period, we measured various markers of oxidative stress and overall health in these children. Our findings revealed that the combination of omega-3 and Manuka honey showed more effectiveness in managing oxidative stress than either Manuka honey alone or the conventional treatment. This suggests that integrating omega-3 into their treatment plan could offer better outcomes for managing the health challenges associated with β-thalassemia.
Ultimately, our research highlights the potential role of omega-3 as a beneficial component in the treatment of anemia related to oxidative stress in pediatric patients. By addressing both oxidative stress and iron overload, we hope this approach leads to improved management strategies for young individuals dealing with this inherited condition.
8.8
Improved anaemia management
Most Useful Review
I began using Now supplements for my overall health. As a CKD sufferer, I must be cautious with the supplements I take. I can confidently say these have significantly improved my condition, especially concerning the anaemia associated with CKD. The pills are easy to swallow, offer great value, and have no discernible taste.
Coenzyme Q10
8
Coenzyme Q10 shows promise for anemia
Disruption of mitochondrial energy metabolism is a putative pathogenesis of Diamond-Blackfan anemia.
Most Relevant Research
We explored the effects of coenzyme Q10 on anemia, particularly in the context ofDiamond-Blackfan anemia, a disorder linked to issues with red blood cell production. In our investigation, we examined how mitochondrial energy metabolism plays a critical role in the health of red blood cell progenitors.
Through a primary cell model, we suppressed the mitochondrial oxidative phosphorylation (OXPHOS) pathway, which led to complications in the differentiation of erythroid cells and disrupted ribosome production. Notably, the mutated genes associated with OXPHOS in patients with Diamond-Blackfan anemia contributed to this malfunction.
When we applied coenzyme Q10—known to activate the OXPHOS pathway—we observed significant improvements in the erythroid defects that arose from the suppression. This compound not only helped in rescuing the erythroid development but also boosted the expression of a crucial protein involved in ribosome biogenesis.
Overall, our study points to coenzyme Q10 as a promising candidate for addressing anemia arising from mitochondrial issues, emphasizing its potential therapeutic impact in conditions like Diamond-Blackfan anemia.
Through a primary cell model, we suppressed the mitochondrial oxidative phosphorylation (OXPHOS) pathway, which led to complications in the differentiation of erythroid cells and disrupted ribosome production. Notably, the mutated genes associated with OXPHOS in patients with Diamond-Blackfan anemia contributed to this malfunction.
When we applied coenzyme Q10—known to activate the OXPHOS pathway—we observed significant improvements in the erythroid defects that arose from the suppression. This compound not only helped in rescuing the erythroid development but also boosted the expression of a crucial protein involved in ribosome biogenesis.
Overall, our study points to coenzyme Q10 as a promising candidate for addressing anemia arising from mitochondrial issues, emphasizing its potential therapeutic impact in conditions like Diamond-Blackfan anemia.
8.8
Increased energy
Most Useful Review
Doctors Best High Absorption coQ10 has significantly boosted my energy levels. I have thalassemia anemia, which isn't treatable with medications, but this product is quite affordable and helps me a great deal.
Zinc
8
Zinc improves anaemia outcomes
Predictors of Anaemia Among Young Children Receiving Daily Micronutrient Powders (MNPs) for 24 Weeks in Bangladesh: A Secondary Analysis of the Zinc in Powders Trial.
Most Relevant Research
We set out to explore how zinc, through micronutrient powders (MNPs), influences anaemia in young children, particularly in Bangladesh, where high rates of anaemia persist. In a well-structured trial, we observed children aged 9-11 months receiving daily doses of MNPs for 24 weeks. Initially, a staggering 54.1% of these children had anaemia, characterized by low hemoglobin levels.
At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.
Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.
Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
9.5
Improved anemia treatment
Most Useful Review
Top product! This zinc is an excellent form of assimilation and does not upset my stomach. I decided to try it after reading about its benefits, and it's now an essential supplement for me, especially in combination with copper. I take it with meals to address my anemia. The capsules are small, and the packaging is lovely.
Vitamin D3
5
Impact of vitamin D on anemia
Impact of supplementation with iron-folic acid (IFA) and vitamin D compared with IFA alone on haemoglobin levels in elderly people with mild-to-moderate anaemia: protocol for the double-blind, randomised, placebo-controlled Iron and vitamin D trial in Elderly Anemia (IDEA).
Most Relevant Research
We conducted a study to investigate the impact of vitamin D3 in combination with iron-folic acid (IFA) on anemia among elderly individuals experiencing mild-to-moderate anemia. This community-based trial involved participants aged 60 and older, who were randomly assigned to receive either the combination of IFA and vitamin D3 or just IFA along with a placebo.
Our research aimed to understand how this supplementation could affect hemoglobin levels and other related markers. Given the complex nature of anemia in older adults—often linked to chronic diseases—Vitamin D3's potential role in enhancing iron utilization was particularly intriguing, especially as it has shown to lower hepcidin levels, a protein that inhibits iron absorption.
While our study design was robust, including a double-blinded and randomized approach, it’s important to note that the results regarding the effectiveness of Vitamin D3 alongside iron-folic acid are not yet confirmed. We hope to provide further insights into the relationship between these supplements and anemia in the elderly, contributing to better treatment options in the future.
Our research aimed to understand how this supplementation could affect hemoglobin levels and other related markers. Given the complex nature of anemia in older adults—often linked to chronic diseases—Vitamin D3's potential role in enhancing iron utilization was particularly intriguing, especially as it has shown to lower hepcidin levels, a protein that inhibits iron absorption.
While our study design was robust, including a double-blinded and randomized approach, it’s important to note that the results regarding the effectiveness of Vitamin D3 alongside iron-folic acid are not yet confirmed. We hope to provide further insights into the relationship between these supplements and anemia in the elderly, contributing to better treatment options in the future.
9.5
Significant vitamin increase
Most Useful Review
My vitamin D rose from 14.2 to 45.3 ng/ml in 8 months, after I started taking 5000 IU alongside Omega-3. I noticed improvements in bone pain, hair loss, and energy levels after starting the supplement. Following my endocrinologist's advice, I adjusted the timing of my intake for better absorption. Vitamin D likely aided my recovery from coronavirus, and I aim to increase my levels further to enhance my health alongside managing my anaemia.
