Quercetin
9
Quercetin alleviates asthma symptoms
Quercetin inhibits ferroptosis through the SIRT1/Nrf2/HO-1 signaling pathway and alleviates asthma disease.
Most Relevant Research
We explored how quercetin, a natural compound found in fruits and vegetables, can impact asthma symptoms. Using an ovalbumin-induced mouse model of asthma, we aimed to uncover whether quercetin can help inhibit a process known as ferroptosis, potentially offering a new therapeutic approach for asthma sufferers.
Our findings showed that quercetin effectively reduced inflammation in the asthmatic mice. Specifically, it lowered levels of inflammatory factors such as IL-4, IL-5, and IL-13—substances typically elevated during an asthma attack. Notably, we also observed that quercetin increased the levels of superoxide dismutase, an important antioxidant, while decreasing malondialdehyde and ferric ions that are associated with oxidative stress.
Additionally, quercetin appeared to boost the expression of key proteins involved in defending against oxidative stress, specifically SIRT1, Nrf2, and HO-1. This suggests that quercetin not only helps combat inflammation but may also protect against cellular damage within the lungs. Overall, our study indicates that quercetin holds promise as a beneficial treatment for asthma by addressing both inflammatory and oxidative stress pathways.
Our findings showed that quercetin effectively reduced inflammation in the asthmatic mice. Specifically, it lowered levels of inflammatory factors such as IL-4, IL-5, and IL-13—substances typically elevated during an asthma attack. Notably, we also observed that quercetin increased the levels of superoxide dismutase, an important antioxidant, while decreasing malondialdehyde and ferric ions that are associated with oxidative stress.
Additionally, quercetin appeared to boost the expression of key proteins involved in defending against oxidative stress, specifically SIRT1, Nrf2, and HO-1. This suggests that quercetin not only helps combat inflammation but may also protect against cellular damage within the lungs. Overall, our study indicates that quercetin holds promise as a beneficial treatment for asthma by addressing both inflammatory and oxidative stress pathways.
9.5
Effective for allergies
Most Useful Review
Quercetin and bromelain are potent natural ingredients that alleviate allergic and inflammatory disorders like asthma. As someone with arthritis and multiple allergies, Quercetin has been my salvation. I take it regularly and highly recommend it!
9.5
Asthma relief
Most Useful Review
I found this product when my daughter suffered from severe sore throats and swollen tonsils. The doctor mentioned tonsil removal, so I researched natural options. This product cleared her throat swiftly, and she rarely gets sore throats now. I also recommended it to a friend with asthma who usually develops bronchitis in winter. If she takes it early, it prevents her condition from worsening.
9.5
Improved breathing
Most Useful Review
I had a terrible asthma episode with severe coughing and shortness of breath. After using this product for just two days, I felt a significant improvement.
N Acetyl L Cysteine
9.5
Supports respiratory health
Most Useful Review
NAC is a powerful antioxidant that I used for my wife’s asthma. It aids in lung functions and reduces mucus thickness, supporting conditions like emphysema and bronchitis. While this product is high quality, I found that the small package lasts less than two months. The capsule is tasteless and beneficial for recovery.
8.3
Effective addition
Most Useful Review
Acetylcysteine significantly helped my asthma when added to my therapy. It alleviated my severe asthma symptoms after changing my supplements.
Oleuropein
9.5
Immune boost observed
Most Useful Review
The main active substance in the leaves is OLEUROPEIN, a powerful antioxidant and herbal antibiotic. This product is fantastic for helping with asthma and boosts the immune system while lowering blood pressure.
8.8
Asthma recovery noted
Most Useful Review
It's antiviral and antibacterial, so when my family has a cold, I take 4 to 5 tablets and feel refreshed the next day. Having asthma, my cold recovered quickly, and my cough did not worsen. I've noticed some improvement with the warts on my son's feet after two weeks of use. I plan to keep observing my family's progress.
Oregano
9.5
Off medication
Most Useful Review
I refer to this as my miracle supplement. I have used this product since autumn 2009 alongside my allergy and asthma medication. Over time, I noticed significant improvements and no longer needed my prescriptions. I now combine this product with NOW brand Quercetin with Bromelain, and I am off my allergy and asthma medications. I increase my intake during allergy season, monitoring closely to avoid an asthma attack.
8.8
Cough relief
Most Useful Review
Oregano oil is suitable for acute and chronic coughs, utilised as an expectorant and cough reliever. It combats infectious agents in the respiratory tract, making it a helpful adjunct for managing simple colds and flu. Oregano oil can relieve sore throats, coughs, and asthma, along with viral and bacterial infections.
Polygonum Cuspidatum Complex
9.5
Asthma improvement
Most Useful Review
I absolutely love this product! It has high quality and I notice the benefits right away when I take it in the morning: more energy and reduced inflammation. I've experienced a significant improvement in my allergic asthma and don't even need to take it daily. Just be cautious if you're sensitive, as it may affect your sleep. I highly recommend it; I've been using it for around 3 years with great benefits (not daily, only when tired).
8.8
Inflammation reduction
Most Useful Review
Excellent product at a great price! It's easy to take, has no unpleasant taste, and significantly helps me manage inflammation and my allergic asthma.
Ginkgo
9.5
Improves asthma symptoms
Most Useful Review
Ginkgo biloba is known for its therapeutic effects, including enhancing cognitive function and reducing symptoms of chronic diseases. My grandmother experiences relief from headaches and improved clarity of thought, aiding her asthma as well. It has numerous benefits in promoting wellness and easing health concerns.
8.8
Assists with asthma
Most Useful Review
Ginkgo biloba effectively dilates blood vessels and increases their elasticity. It helps treat various conditions, including asthma and myocardial infarction. The plant offers benefits such as improving circulation, alleviating depression, and enhancing blood flow, which can aid asthma sufferers. However, prolonged use may heighten stroke risks, so caution is advised.
Vitamins
9
Combined effects on asthma treatment
A systematic pharmacological strategy-based to decode the synergistic mechanism of 7,4'-dihydroxyflavone in combination with vitamin D3 against asthma.
Most Relevant Research
We explored how vitamin D3 can play a role in asthma treatment, particularly when combined with 7,4'-dihydroxyflavone (74DHF). Our study took a systems pharmacology approach, which means we looked at how these two compounds might work together at a molecular level to combat asthma.
Through our analysis, we identified 47 overlapping targets, 20 core targets, and key pathways associated with asthma relief. We observed that this combination could help reduce inflammatory responses in immune cells and counteract changes in bronchial epithelial cells that contribute to asthma severity.
Although the potential benefits of vitamin D3 combined with 74DHF are promising, we must emphasize that the specific isolated effects of vitamin D3 alone were not assessed, making it challenging to determine its individual contribution. Nonetheless, this study highlights an innovative strategy for developing combination therapies in asthma management.
Through our analysis, we identified 47 overlapping targets, 20 core targets, and key pathways associated with asthma relief. We observed that this combination could help reduce inflammatory responses in immune cells and counteract changes in bronchial epithelial cells that contribute to asthma severity.
Although the potential benefits of vitamin D3 combined with 74DHF are promising, we must emphasize that the specific isolated effects of vitamin D3 alone were not assessed, making it challenging to determine its individual contribution. Nonetheless, this study highlights an innovative strategy for developing combination therapies in asthma management.
9.5
Cough relief
Most Useful Review
I found this supplement effective for my coughing and asthma. After using many inhalers with little success, I discovered that vitamin D could help. Within two days of starting this product, I noticed a significant reduction in my cough. For three years now, I haven't had a cold. I'm grateful for this supplement, which I can't find in Japan, and to the doctor whose article helped me.
Fish Oil
4
Fatty acids and equine asthma
Fatty acid fingerprints in bronchoalveolar lavage fluid and its extracellular vesicles reflect equine asthma severity.
Most Relevant Research
We explored the connection between fatty acid profiles and the severity of equine asthma, an inflammatory condition affecting horses' lower airways. By analyzing samples of bronchoalveolar lavage fluid (BALF) from healthy horses and those with varying degrees of asthma severity, we aimed to uncover how specific fatty acids, particularly eicosapentaenoic acid (EPA), relate to inflammatory status.
Our findings highlighted distinct patterns in the fatty acid compositions among the different groups. While eicosapentaenoic acid levels increased in the extracellular vesicles of horses suffering from severe asthma, it was not clear whether this increase alone translated to any significant clinical benefit. All asthmatic horses exhibited elevated levels of dihomo-γ-linolenic acid, indicating a complex balance between pro-inflammatory and resolving actions of these fatty acids.
Through this study, we gained new insights into how fatty acid profiles vary with asthma severity, but the effectiveness of eicosapentaenoic acid treatment for asthma remains ambiguous. It appears that while EPA may have a role, other lipid mediators also significantly influence asthma pathology, complicating our understanding of its potential as a treatment option.
Our findings highlighted distinct patterns in the fatty acid compositions among the different groups. While eicosapentaenoic acid levels increased in the extracellular vesicles of horses suffering from severe asthma, it was not clear whether this increase alone translated to any significant clinical benefit. All asthmatic horses exhibited elevated levels of dihomo-γ-linolenic acid, indicating a complex balance between pro-inflammatory and resolving actions of these fatty acids.
Through this study, we gained new insights into how fatty acid profiles vary with asthma severity, but the effectiveness of eicosapentaenoic acid treatment for asthma remains ambiguous. It appears that while EPA may have a role, other lipid mediators also significantly influence asthma pathology, complicating our understanding of its potential as a treatment option.
9.5
Effective asthma treatment
Most Useful Review
It helps with asthma very effectively, especially when taken with zinc and magnesium.
Zinc
8
Zinc may lower asthma risk
Micronutrients and Allergic Diseases: A Mendelian Randomization Study.
Most Relevant Research
We explored the possible link between zinc levels in the body and the risk of developing allergic asthma. In a comprehensive analysis, we looked at various micronutrients and their potential impact on allergic diseases, particularly focusing on zinc.
Our findings suggest that higher serum zinc concentrations might actually reduce the risk of allergic asthma. This means that adequate levels of zinc could play a significant role in preventing this common respiratory condition. However, it's essential to approach these results with careful consideration and see them as part of a broader dietary picture.
While zinc showed a promising association, the study also revealed complexities in how different micronutrients interact with allergic conditions. As we delve deeper into the relationship between nutrition and health, the role of zinc stands out as an area worth further exploration.
Overall, this study provides valuable insight into how dietary choices, specifically related to zinc intake, could influence asthma outcomes. Our findings underline the importance of understanding micronutrients not just as supplements, but as key players in our overall health.
Our findings suggest that higher serum zinc concentrations might actually reduce the risk of allergic asthma. This means that adequate levels of zinc could play a significant role in preventing this common respiratory condition. However, it's essential to approach these results with careful consideration and see them as part of a broader dietary picture.
While zinc showed a promising association, the study also revealed complexities in how different micronutrients interact with allergic conditions. As we delve deeper into the relationship between nutrition and health, the role of zinc stands out as an area worth further exploration.
Overall, this study provides valuable insight into how dietary choices, specifically related to zinc intake, could influence asthma outcomes. Our findings underline the importance of understanding micronutrients not just as supplements, but as key players in our overall health.
9.5
Strengthened immunity
Most Useful Review
I've been using Now Foods Zinc Picolinate for about a year due to my asthma and frequent illness. Since taking it, I've only been ill once in the past year, as it has bolstered my immune system. I highly recommend this product!
Coenzyme Q10
8
Co-Q10 shows promise for asthma
The effect of Co-Q10 on allergic rhinitis and allergic asthma.
Most Relevant Research
We explored how Coenzyme Q10 (Co-Q10) could potentially help individuals suffering from allergic asthma and rhinitis. Through our research, we treated animal models that had developed these allergic conditions using Co-Q10 alone, in addition to combinations with O-3 and Mg-S.
We conducted detailed analyses, measuring various factors such as cytokines and allergic mediators, as well as gene expression related to inflammation. Our findings indicated that Co-Q10 plays a significant role by activating a protective protein called Nrf2. This activation seems to help in managing asthma and allergic reactions more effectively.
Overall, Co-Q10 demonstrates a promising approach in enhancing the body's defense against allergens, helping control the type of inflammation that leads to asthma symptoms. By elevating Nrf2 expression, Co-Q10 helps reduce allergic mediators, making it a potential ally in the fight against asthma.
We conducted detailed analyses, measuring various factors such as cytokines and allergic mediators, as well as gene expression related to inflammation. Our findings indicated that Co-Q10 plays a significant role by activating a protective protein called Nrf2. This activation seems to help in managing asthma and allergic reactions more effectively.
Overall, Co-Q10 demonstrates a promising approach in enhancing the body's defense against allergens, helping control the type of inflammation that leads to asthma symptoms. By elevating Nrf2 expression, Co-Q10 helps reduce allergic mediators, making it a potential ally in the fight against asthma.
9.5
Better asthma control
Most Useful Review
This has helped in keeping my asthma under control, so I don't need my inhalers as frequently.