Supplements best matching Irritable bowel syndrome

Explore top-rated supplements for Irritable Bowel Syndrome, backed by published studies and thousands of verified reviews. Unlike generic supplement rankings, every score here is specific to Irritable Bowel Syndrome: our AI reads peer-reviewed research AND thousands of verified user reviews, so each rating reflects what actually worked for real people with Irritable Bowel Syndrome — not how well the product sells. Choose a product to read more about the science and real experiences behind it.

Research Contributors

Peer-reviewed research on Irritable Bowel Syndrome cited on Digdep includes work by 87 researchers. Featured contributors (sorted by H-index):

Arthur C. Ouwehand

Wellcome Sanger Institute
H-index 48 2,893 citations 2 cited here

Hania Szajewska

Department of Pediatrics, The Medical University of Warsaw, Warsaw, Poland
H-index 40 4,850 citations 9 cited here

Sunita Vohra

Department of Pediatrics, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta
H-index 39 2,572 citations 9 cited here

Marco Gobbetti

Faculty of Science and Technology, Free University of Bolzano, piazza Università, 5, 39100 Bolzano, Italy
H-index 30 1,425 citations 10 cited here

Premysl Bercik

Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada
H-index 28 2,980 citations 1 cited here

Elizabeth A. Williams

Department of Nutrition, University of California, Davis
H-index 26 723 citations 1 cited here

Andrei V. Iakovenko

University of Maryland, College Park
H-index 25 3,245 citations 7 cited here

Vincenzo Stanghellini

IRCCS Azienda Ospedaliero-Universitaria di Bologna, I-40138 Bologna, Italy
H-index 25 1,456 citations 9 cited here

Piero Portincasa

Clinica Medica “A. Murri”, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, 70121 Bari, Italy
H-index 23 2,350 citations 10 cited here

Vladimir I Pilipenko

Space Research Institute of the Russian Academy of Sciences
H-index 23 1,214 citations 2 cited here

Chengfu Xu

University of California, Los Angeles
H-index 23 789 citations 3 cited here

Kathryn Murray

Stanford University
H-index 22 1,023 citations 2 cited here

Xu Han

University of Michigan, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Ann Arbor, MI, USA.
H-index 22 732 citations 9 cited here

Tari M. A. George Michael

Internal Medicine Department, Faculty of Medicine Ain Shams University, Cairo, Egypt
H-index 22 320 citations 3 cited here

David Gunn

Stanford University
H-index 20 1,200 citations 2 cited here

Alexander N. Ivanov

Stanford University
H-index 20 1,024 citations 7 cited here

Domenica M. Di Palo

Clinica Medica “A. Murri” Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, Bari, Italy
H-index 18 376 citations 10 cited here

Vasily A Isakov

University of California, Berkeley
H-index 18 320 citations 2 cited here

Edgar Torres-Maravilla

Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France
H-index 17 1,023 citations 2 cited here

Claire E. Williams

University of California, Berkeley
H-index 15 987 citations 1 cited here
Product Science Score User Score
Vitamin Bs
Product NOW Foods, Pantothenic Acid, 500 mg, 100 Veg Capsules
9
8.1
Product NOW Foods, B-100, 100 Veg Capsules
N/A
8.2
Wheat Grass
Product Amazing Grass, Organic Wheat Grass Powder, 1.76 lb (800 g)
9
7.9
Garlic
Product Kyolic, Aged Garlic Extract™, Cardiovascular Health, Original Formula 100, 600 mg, 300 Capsules (300 mg Per Capsule)
8.5
8.4
Product NOW Foods, Garlic Oil, 1,500 mg, 250 Softgels
8.5
8.2
Pectin
Product NOW Foods, Apple Pectin, 700 mg, 120 Veg Capsules
9
7.7
B12
Product NOW Foods, B-12, 1,000 mcg, 100 Lozenges
8
8.5
Magnesium
Product Doctor's Best, High Absorption Magnesium Powder, 7.1 oz (200 g)
8
8.4
Product NATURELO, Magnesium Glycinate Chelate Complex, 120 Vegetarian Capsules
8
8.4
Product Solgar, Magnesium with Vitamin B6, 250 Tablets
8.1
8.1
Product Nature Made, Magnesium, 250 mg, 200 Tablets
8
8.2
Product NOW Foods, Magnesium & Potassium Aspartate, 120 Veg Capsules
8
8.2
Product Solgar, Magnesium Citrate, 60 Tablets
8
8.1
Product Nature's Bounty, Magnesium, 500 mg, 100 Coated Tablets
8
8
Product NOW Foods, Magnesium Caps, 400 mg, 180 Veg Capsules
8
7.8
Product NOW Foods, Magnesium Malate, 1,000 mg, 180 Tablets
8
7.5
Product NOW Foods, Magnesium Citrate, 400 mg, 120 Veg Capsules (133 mg per Capsule)
8
7.5
Product Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet)
8
7.2
Product Life Extension, Magnesium Caps, 500 mg, 100 Vegetarian Capsules
8
6
Beta Glucan
Product NOW Foods, Beta-Glucans, with ImmunEnhancer, Extra Strength, 250 mg, 60 Veg Capsules
7.9
8.4
Calcium Magnesium
Product NOW Foods, Calcium & Magnesium, 250 Tablets
8.5
7.8
Product Country Life, Target-Mins, Calcium Magnesium with Vitamin D Complex, 240 Vegan Capsules
7.6
8.5
Product NOW Foods, Magnesium & Calcium, 250 Tablets
7
8
B6 Pyridoxine
Product Solgar, Vitamin B6, 25 mg, 100 Tablets
8.2
8.1
L Taurine
Product NOW Foods, Double Strength Taurine, 1,000 mg, 250 Veg Capsules
8
8.2
Lactoferrin
Product Jarrow Formulas, Lactoferrin, Freeze Dried, 250 mg, 60 Capsules
8
8
L Glutamine
Product Jarrow Formulas, L-Glutamine, 1,000 mg, 100 Tablets
7.7
8.3
Pre Post Natal Formulas
Product Garden of Life, Dr. Formulated Probiotics, Once Daily Prenatal (no refrigeration required), 30 Vegetarian Capsules
7.6
8.4
Lactobacillus
Product Jarrow Formulas, Jarro-Dophilus EPS, 10 Billion CFU, 60 Veggie Capsules
7.7
8.2
Product Jarrow Formulas, Vegan Fem Dophilus, 1 Billion CFU, 60 Veggie Capsules
7.6
7.5
Product Culturelle, Probiotics, Digestive Daily Probiotic, 50 Once Daily Vegetarian Capsules
7.3
7.8
Iron
Product Garden of Life, Vitamin Code, RAW Iron, 30 Vegan Capsules
7.4
8.5
Product Solgar, Gentle Iron®, 25 mg, 90 Vegetable Capsules
6.8
7.3
Calcium
Product Garden of Life, Vitamin Code, RAW Calcium, 120 Vegetarian Capsules
7.6
8.3
Product Nature's Bounty, Calcium Magnesium Zinc with Vitamin D3, 100 Coated Caplets
7.4
7.9
Probiotics
Product Garden of Life, RAW Probiotics, Colon Care, 30 Vegetarian Capsules
7.5
8.4
Product American Health, Chewable Acidophilus, Natural Strawberry, 1 Billion CFU, 60 Chewable Wafers
7.4
8.4
Product NOW Foods, Probiotic-10, 100 Billion, 60 Veg Capsules
7.4
8.4
Product Renew Life, Women's Care Probiotic, 50 Billion CFU, 60 Vegetarian Capsules
7.4
8.3
Product NOW Foods, 8 Billion Acidophilus & Bifidus, 120 Veg Capsules
7.7
8
Product Garden of Life, Dr. Formulated Probiotics, Once Daily Men's, 50 Billion, 30 Vegetarian Capsules
7.6
8
Product Garden of Life, Primal Defense, Ultra, Ultimate Probiotic Formula, 90 UltraZorbe Vegetarian Capsules
7.5
8
Product Culturelle, Probiotics, Ultimate Strength Probiotic, 20 Billion CFU, 30 Vegetarian Capsules
7
8.3
Product NOW Foods, Saccharomyces Boulardii, Probiotic , 5 Billion CFU, 60 Veg Capsules
7.4
7.9
Product Solgar, Advanced 40+ Acidophilus, 120 Vegetable Capsules
7.3
8
Product NOW Foods, Acidophilus Two Billion, 2 Billion CFU, 250 Veg Capsules
7.3
7.9
Product Jarrow Formulas, Vegan Saccharomyces Boulardii + MOS, 5 Billion CFU, 180 Veggie Capsules
7.4
7.8
Product Garden of Life, Dr. Formulated Probiotics, Mood+, 60 Vegetarian Capsules
7.5
7.7
Product 21st Century, Acidophilus Probiotic Blend, 150 Capsules
7.4
7.5
Product Garden of Life, Vitamin Code, RAW Prenatal, 90 Vegetarian Capsules
N/A
8
Product 21st Century, Cranberry Plus Probiotic, 60 Tablets
N/A
7.6
Product NOW Foods, Berry Dophilus, Kids, 2 Billion CFU, 120 Chewables
N/A
7.6
Childrens Probiotics
Product Garden of Life, Dr. Formulated Probiotics, Organic Kids + Probiotics + Vitamins C & D Chewables, Tasty Organic Watermelon, 30 Yummy Chewables
7.6
8.2
Product Garden of Life, Dr. Formulated Probiotics, Organic Kids +, Tasty Organic Strawberry Banana, 30 Yummy Chewables
7.6
7.4
Product BioGaia, Protectis Baby, Probiotic Drops with Vitamin D3, 0.34 fl oz (10 ml)
7.5
7.5
Product Culturelle, Kids, Purely Probiotics®, 1+ Years, 5 Billion CFU, 50 Single Serve Packets, 0.05 oz (1.5 g) Each
N/A
7.9
B3 Niacin
Product NOW Foods, Niacin, Flush-Free, Double Strength, 500 mg, 180 Veg Capsules
7.5
8.2
N Acetyl Cysteine Nac
Product Doctor's Best, NAC Detox Regulators with Seleno Excell®, 60 Veggie Caps
7.9
7.8
Turmeric Curcumin
Product Jarrow Formulas, Curcumin 95, Turmeric Extract, 500 mg, 120 Veggie Capsules
6.9
8.6
Inositol
Product NOW Foods, Inositol Capsules, 500 mg, 100 Veg Capsules
7.5
8
Colon Cleanse
Product Nature's Secret, Multi-Herb Colon Cleanse, 275 Tablets
7.5
7.8
Vitamins
Product NOW Foods, Vitamin D-3, High Potency, 5,000 IU, 120 Softgels
7.4
7.8
Product NOW Foods, Vitamin A, 25,000 IU, 250 Softgels
N/A
8.5
L Glutathione
Product NOW Foods, Glutathione, 500 mg, 60 Veg Capsules
7
8
Milk Thistle Silymarin
Product NOW Foods, Milk Thistle Extract, Double Strength, 300 mg, 200 Veg Capsules
7
7.6
Prebiotic Fiber Inulin
Product NOW Foods, Certified Organic Inulin, Prebiotic Pure Powder, 8 oz (227 g)
6.8
7.7
Omega 3 Fish Oil
Product Nordic Naturals, Omega-3, Great Lemon, 690 mg, 120 Soft Gels (345 mg per Soft Gel)
6
8.1
Product NOW Foods, Omega-3 Fish Oil, 1,000 mg, 180 EPA - 120 DHA, 100 Softgels
6
8
Enzymes
Product Doctor's Best, High Absorption CoQ10 with BioPerine®, 100 mg, 120 Veggie Caps
N/A
8.5
Product Doctor's Best, Natto-Serra, 90 Veggie Caps
N/A
8.2
Product Doctor's Best, High Potency Serrapeptase, 120,000 SPU, 270 Veggie Caps
N/A
8.1
Quercetin
Product NOW Foods, Quercetin with Bromelain, 120 Veg Capsules
N/A
8.5
MSM
Product Doctor's Best, MSM with OptiMSM®, 3,000 mg, 360 Capsules (1,000 mg per Capsule)
N/A
8.5
Other
Product Jarrow Formulas, Evening Primrose, 1,300 mg, 60 Softgels
N/A
8.4
Product NOW Foods, Dairy Digest Complete, 90 Veg Capsules
N/A
8.4
Product American Health, Papaya Enzyme with Chlorophyll, 250 Chewable Tablets
N/A
8.3
Product VitaFusion, Fiber Well™ Gummies, Peach, Strawberry, and Berry, 90 Gummies
N/A
8.3
Product NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels
N/A
8.2
Product NOW Foods, C-1000 with Bioflavonoids, 250 Veg Capsules
N/A
8.1
Product Life Extension, MacuGuard, Ocular Support with Saffron & Astaxanthin, 60 Softgels
N/A
8.1
Product Traditional Medicinals, Smooth Move Capsules, Senna, 50 Capsules
N/A
7.9
Product Doctor's Best, Hyaluronic Acid + Chondroitin Sulfate with BioCell Collagen, 180 Veggie Capsules
N/A
7.9
Product Nature's Way, Organic MCT Oil, 16 fl oz (480 ml)
N/A
7.7
Product NOW Foods, Psyllium Husk Caps, 700 mg, 180 Veg Capsules
N/A
7.2
Lutein
Product NOW Foods, Lutein, 10 mg, 120 Softgels
N/A
8.4
Product NOW Foods, Double Strength Lutein, 20 mg, 90 Veg Capsules
N/A
8.2
Product Doctor's Best, Lutein from OptiLut, 20 mg, 120 Veggie Caps (10 mg per Capsule)
N/A
8.2
Ginger Oil
Product NOW Foods, Essential Oils, Ginger, 1 fl oz (30 ml)
N/A
8.4
Spirulina
Product Nutrex Hawaii, Pure Hawaiian Spirulina, Powder, 16 oz (454 g)
N/A
8.4
Product NOW Foods, Certified Organic Spirulina, Double Strength, 1,000 mg, 120 Tablets
N/A
7.9
Multivitamins
Product Navitas Organics, Organic Superfood+® Adaptogen Blend, 6.3 oz (180 g)
N/A
8.3
Product Nature's Way, Mega-Zyme, Systemic Enzymes, 100 Tablets
N/A
8.3
Product American Health, Chewable Super Papaya Enzyme Plus, 360 Tablets
N/A
8.2
Product NOW Foods, Super Enzymes, 180 Capsules
N/A
8.1
Flax Seed Supplements
Product NOW Foods, Flax Oil, 1,000 mg, 100 Softgels
N/A
8.3
Oregano Oil Supplements
Product North American Herb & Spice, Oreganol, Oil of Wild Oregano, 1 fl oz (30 ml)
N/A
8.3
Product Gaia Herbs, Oil of Oregano, 60 Vegan Liquid Phyto-Caps
N/A
8
Vitamin C
Product Solgar, Ester-C® Plus, Vitamin C, 1,000 mg, 180 Tablets
N/A
8.3
Product NOW Foods, C-1000, 250 Tablets
N/A
8.1
Product Solaray, Timed Release Vitamin C with Rose Hips & Acerola, 1,000 mg, 250 Tablets
N/A
8
N Acetyl Glucosamine
Product Jarrow Formulas, N-A-G, 700 mg, 120 Veggie Capsules
N/A
8.2
Bromelain
Product Doctor's Best, High Potency Bromelain, 500 mg, 90 Veggie Caps
N/A
8.2
Barley Grass
Product Green Foods, Green Magma®, Barley Grass Juice Powder, 10.6 oz (300 g)
N/A
8.2
Alfalfa
Product NOW Foods, Alfalfa, 650 mg, 500 Tablets
N/A
8.2
Mct Oil
Product Nutiva, Organic MCT Oil, 32 fl oz (946 ml)
N/A
8.2
Product BulletProof, MCT Oil, 16 fl oz (473 ml)
N/A
8.2
Slippery Elm
Product NOW Foods, Slippery Elm, 400 mg, 100 Veg Capsules
N/A
8.2
Ascorbic Acid
Product NOW Foods, Vitamin C Crystals, 1 lb (454 g)
N/A
8.1
D Mannose
Product NOW Foods, D-Mannose Pure Powder, 6 oz (170 g)
N/A
8.1
Zinc Magnesium Aspartate
Product NOW Foods, Sports, ZMA, Sports Recovery, 180 Veg Capsules
N/A
8
Psyllium Husk
Product NOW Foods, Certified Organic Whole Psyllium Husks, 12 oz (340 g)
N/A
8