Glucosamine Chondroitin Formulas
9
Erenumab reduces migraine medication use
We explored how treatment with erenumab affects the use of acute migraine medications. This study analyzed data from two large clinical trials involving nearly 1,600 participants suffering from episodic migraine (EM) and chronic migraine (CM). Patients received either erenumab or a placebo monthly for treatment, while they recorded their medication usage in an electronic diary.
Our findings highlighted that erenumab not only reduces the frequency of acute headaches but also leads to a significant decrease in the use of acute headache medications, particularly migraine-specific medications like triptans and ergots. This suggests that treating migraines with erenumab may help minimize the risk of over-reliance on acute medication, which can sometimes lead to adverse health situations, such as medication overuse headache.
Overall, the treatment with erenumab proves promising for anyone looking to manage their migraine efficiently, allowing patients to experience relief while reducing their dependency on other acute medications.
Our findings highlighted that erenumab not only reduces the frequency of acute headaches but also leads to a significant decrease in the use of acute headache medications, particularly migraine-specific medications like triptans and ergots. This suggests that treating migraines with erenumab may help minimize the risk of over-reliance on acute medication, which can sometimes lead to adverse health situations, such as medication overuse headache.
Overall, the treatment with erenumab proves promising for anyone looking to manage their migraine efficiently, allowing patients to experience relief while reducing their dependency on other acute medications.
9.5
Reduces migraine frequency
Most Useful Review
GREAT It normalises sleep with regular intake of 2 capsules. It improves my migraines significantly. When the special effects begin, I take my usual pills, add extra magnesium, and the migraine fades within a couple of hours, compared to the previous half-day disruption. The frequency has also decreased alongside medicinal support. Regular magnesium intake eases PMS and periods, so I remain calmer, and I can even go a day without painkillers. Chronic pain in my nasopharynx hardly worsens. I also take omega-3, serrapeptase, and resveratrol, but I believe magnesium plays a role. Taking magnesium, lecithin, and protein has shown a genuine effect with collagen. I was pleasantly surprised. No allergies, rashes, or digestive issues. Quality is excellent with natural ingredients.
L Glutathione
9
We explored the effects of an aqueous extract from Ligusticum chuanxiong, known as LCH, on migraine, particularly focusing on the role of glutathione—a powerful antioxidant that may impact migraine symptoms. Using a solid study design that involved NTG-induced migraine models in mice and rats, we conducted various tests to observe changes in cerebral blood flow, metabolite profiles, and molecular pathways related to glutathione metabolism.
During our evaluations, we observed that LCH significantly influenced the levels of several metabolites linked to migraine. Notably, we identified glutathione metabolism as a key player in this process, suggesting that boosting glutathione levels might help manage migraine symptoms effectively. Our findings showed that LCH treatment enhanced the expression of important components involved in glutathione synthesis, advocating the idea that supporting this pathway could be an innovative strategy for migraine relief.
Overall, the study indicates that the action of LCH on migraine is intricately linked to the glucose-glutamate-Nrf-2 axis, highlighting potential new avenues for migraine treatment that could leverage glutathione’s benefits. This underscores the possibility of integrating traditional herbal remedies into modern therapeutic approaches for managing headaches.
During our evaluations, we observed that LCH significantly influenced the levels of several metabolites linked to migraine. Notably, we identified glutathione metabolism as a key player in this process, suggesting that boosting glutathione levels might help manage migraine symptoms effectively. Our findings showed that LCH treatment enhanced the expression of important components involved in glutathione synthesis, advocating the idea that supporting this pathway could be an innovative strategy for migraine relief.
Overall, the study indicates that the action of LCH on migraine is intricately linked to the glucose-glutamate-Nrf-2 axis, highlighting potential new avenues for migraine treatment that could leverage glutathione’s benefits. This underscores the possibility of integrating traditional herbal remedies into modern therapeutic approaches for managing headaches.
9.5
Reduced headaches
Most Useful Review
An excellent antioxidant! I initially bought it for my husband, but I ended up using it myself. It has made me feel lighter overall, as though it was cleansing me of something harmful. The headaches have disappeared, and it positively affects my blood and general well-being. My blood pressure has stabilised, and migraines have not returned. I liked the effect.
Quercetin
8
We explored how quercetin might alleviate migraine symptoms caused by nitroglycerin in rats. Over a week, we administered quercetin and examined its impact on behavior after inducing migraine pain.
The results were promising; quercetin significantly improved behavioral responses linked to migraine pain, showing a decrease in the severity of symptoms.
Its effectiveness appears to stem from quercetin's antioxidant and anti-inflammatory properties, suggesting it could be a helpful treatment for migraine relief.
The results were promising; quercetin significantly improved behavioral responses linked to migraine pain, showing a decrease in the severity of symptoms.
Its effectiveness appears to stem from quercetin's antioxidant and anti-inflammatory properties, suggesting it could be a helpful treatment for migraine relief.
9.5
Significant improvement
Most Useful Review
After consuming this, I felt much better. Previously, I experienced nasal congestion, inflammation, and migraine due to immune reactions. However, since discovering quercetin as a natural antihistamine, I’ve noticed significant improvement in my symptoms within two days.
Alpha Lipoic Acid
8
We explored the effects of alpha-lipoic acid on migraines as part of a broader study examining dietary fatty acid supplementation. This research particularly assessed how various supplements, including omega-3 fatty acids and alpha-lipoic acid, influence migraine clinical outcomes.
In the systematic review, we considered six randomized controlled trials that included 407 participants suffering from chronic migraines. The studies aimed to determine if fatty acid supplementation could provide relief from headache intensity, frequency, duration, and overall quality of life.
While the results indicated significant improvements with omega-3 supplementation, the specific contributions of alpha-lipoic acid were not strongly highlighted. This makes it challenging to definitively state the effectiveness of alpha-lipoic acid alone in treating migraines. Overall, the findings suggest that while fatty acids, particularly omega-3, show promise for migraine relief, we need more focused research to fully evaluate alpha-lipoic acid's potential benefits.
In the systematic review, we considered six randomized controlled trials that included 407 participants suffering from chronic migraines. The studies aimed to determine if fatty acid supplementation could provide relief from headache intensity, frequency, duration, and overall quality of life.
While the results indicated significant improvements with omega-3 supplementation, the specific contributions of alpha-lipoic acid were not strongly highlighted. This makes it challenging to definitively state the effectiveness of alpha-lipoic acid alone in treating migraines. Overall, the findings suggest that while fatty acids, particularly omega-3, show promise for migraine relief, we need more focused research to fully evaluate alpha-lipoic acid's potential benefits.
9.5
Improved migraine symptoms
Most Useful Review
After taking thiocarnitine for three days, I felt my brain reacted quicker, and my migraine decreased. After three weeks, the recent migraines improved significantly and I felt more refreshed. I will continue taking one tablet a day to help repair damaged nerves and prevent brain degeneration.
B2
8
We investigated how galcanezumab, a medication designed for migraines, affects brain connectivity in patients. By using advanced imaging, we compared 19 patients who experienced significant relief from their migraines to 17 who did not see improvements.
Patients who responded positively to the treatment showed reduced brain connectivity in specific regions linked to sensory processing after three months. Interestingly, those who didn't respond did not exhibit these changes. This suggests that even a short duration of reduced pain signals can lead to positive changes in how the brain processes these signals.
Patients who responded positively to the treatment showed reduced brain connectivity in specific regions linked to sensory processing after three months. Interestingly, those who didn't respond did not exhibit these changes. This suggests that even a short duration of reduced pain signals can lead to positive changes in how the brain processes these signals.
8.8
Helps with migraine
Most Useful Review
Excellent vitamin B2! It aids recovery from viral infections, calms the nervous system, and assists in migraine relief. One capsule contains 100 mg of vegetarian B2, and I take it with food daily. The symptoms of deficiency include dry eyes and irritability. Solgar's quality is impressive, and I've repeatedly found it beneficial.
Sports Fish Oil Omegas
8
In a recent study aimed at understanding the role of eicosapentaenoic acid (EPA) in treating chronic migraines, we conducted a random, placebo-controlled trial with participants diagnosed with chronic migraines. The participants were split into two groups; one group received 1000 mg of EPA twice daily for eight weeks, while the other group took placebo softgels.
Our main focus was to evaluate whether daily EPA supplementation could reduce the frequency of migraine attacks and improve overall quality of life. We carefully tracked symptoms at four and eight weeks, relying on established measures like the Headache Impact Test-6 to quantify changes.
The results from this study were promising. We observed that taking 2000 mg of EPA daily showed potential benefits as a preventative treatment for chronic migraines. Participants reported a decrease in migraine headache days and lower severity levels, making it a valuable option to consider in managing chronic migraines effectively.
Our main focus was to evaluate whether daily EPA supplementation could reduce the frequency of migraine attacks and improve overall quality of life. We carefully tracked symptoms at four and eight weeks, relying on established measures like the Headache Impact Test-6 to quantify changes.
The results from this study were promising. We observed that taking 2000 mg of EPA daily showed potential benefits as a preventative treatment for chronic migraines. Participants reported a decrease in migraine headache days and lower severity levels, making it a valuable option to consider in managing chronic migraines effectively.
10
Migraine relief
Most Useful Review
What a quality omega! The effect is highly noticeable, particularly on my skin. My migraine has disappeared.
Turmeric Curcumin
7
We explored how curcumin, a compound found in turmeric, might help in managing migraines, a condition that affects about 15% of the global population. Curcumin is known for its anti-inflammatory and antioxidant properties, which could potentially address some of the factors that trigger migraine attacks, such as oxidative stress and inflammation.
Through our review of both experimental and clinical studies, we observed that liposomal curcumin and nano-curcumin show promise in reducing the frequency and severity of migraine episodes. However, it’s crucial to note that while the initial findings are encouraging, there is still a need for more comprehensive studies in this area.
These additional studies would help us better understand curcumin's exact effects and mechanisms in alleviating migraine symptoms. We're hopeful that further research will clarify the benefits of curcumin and its potential as an alternative treatment option for those suffering from migraines.
Through our review of both experimental and clinical studies, we observed that liposomal curcumin and nano-curcumin show promise in reducing the frequency and severity of migraine episodes. However, it’s crucial to note that while the initial findings are encouraging, there is still a need for more comprehensive studies in this area.
These additional studies would help us better understand curcumin's exact effects and mechanisms in alleviating migraine symptoms. We're hopeful that further research will clarify the benefits of curcumin and its potential as an alternative treatment option for those suffering from migraines.
9.5
Migraine benefits
Most Useful Review
Curcumin acts as a tonic, analgesic, and hemostatic. Its regular use increases antimicrobial proteins, bolstering immune support against fungi and viruses. I benefit from it for migraines, gallstones, and more. It also lowers cholesterol, preventing thrombosis and atherosclerosis. I take one capsule daily with food.
Magnesium
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
9.5
Reduced migraines
Most Useful Review
Using Magnesium Caps has been transformative! Before, I struggled with constant sleepiness, headaches, irritability, and nervousness. This supplement aids in the absorption of vitamins and minerals, effectively thinning the blood and reducing my migraines. It also helped me overcome insomnia and depression. I now wake refreshed after just six hours of sleep. Highly recommended!
Zinc
4
We explored the potential role of zinc in migraine management through a systematic review of existing studies. Our aim was to gather evidence from scientific databases to see if zinc could be an effective treatment choice, especially considering its known anti-inflammatory and antioxidant properties. We reviewed information from three major databases and identified 35 studies, eventually narrowing our focus to five studies that met our criteria—two clinical trials and three observational studies.
The results of our review suggest that zinc may have a positive impact on managing migraines, though the available evidence is still somewhat limited. The clinical trials we examined showed a low risk of bias, indicating that their results are reliable. However, we also acknowledge that more robust and larger clinical trials are needed to strengthen the evidence around zinc’s effectiveness in treating migraines.
Overall, while the findings are promising, we should approach them with caution until further studies can confirm the benefits of zinc in this context. As of now, the use of zinc for migraine treatment is an area that warrants further exploration.
The results of our review suggest that zinc may have a positive impact on managing migraines, though the available evidence is still somewhat limited. The clinical trials we examined showed a low risk of bias, indicating that their results are reliable. However, we also acknowledge that more robust and larger clinical trials are needed to strengthen the evidence around zinc’s effectiveness in treating migraines.
Overall, while the findings are promising, we should approach them with caution until further studies can confirm the benefits of zinc in this context. As of now, the use of zinc for migraine treatment is an area that warrants further exploration.
10
Migraine relief
Most Useful Review
Excellent! Since I started taking this daily, my PMS migraines have vanished for months.
Dha
9.5
We dug into how docosahexaenoic acid (DHA), along with eicosapentaenoic acid (EPA), can help with migraine management. Through a comprehensive analysis of 40 randomized controlled trials involving over 6,600 participants, we compared various treatments for migraine prevention. Our focus was on the effectiveness and acceptability of high doses of DHA and EPA against other standard medications.
What we found was quite intriguing. Supplementing with high doses of EPA and DHA significantly reduced the frequency of migraines as compared to placebo treatments. In fact, our analysis revealed a notable decrease in migraine severity as well. Not only that, but those using high-dose omega-3s reported favorable experiences with treatment, showcasing a high level of acceptability.
This compelling evidence suggests that high doses of DHA and EPA can serve as a premier option for preventing migraines. Their effectiveness and tolerability make them an attractive choice for those seeking relief. The potential of omega-3 supplementation in this context opens new avenues for migraine management that are worth exploring further.
What we found was quite intriguing. Supplementing with high doses of EPA and DHA significantly reduced the frequency of migraines as compared to placebo treatments. In fact, our analysis revealed a notable decrease in migraine severity as well. Not only that, but those using high-dose omega-3s reported favorable experiences with treatment, showcasing a high level of acceptability.
This compelling evidence suggests that high doses of DHA and EPA can serve as a premier option for preventing migraines. Their effectiveness and tolerability make them an attractive choice for those seeking relief. The potential of omega-3 supplementation in this context opens new avenues for migraine management that are worth exploring further.
8.8
Helpful migraine relief
Most Useful Review
Best! I love this fish oil! It has undoubtedly rejuvenated my skin, which has become more elastic and smoother. At 56, post-menopause, my skin was fading despite hormonal treatments. This supplement, which I call “fish”, has saved my skin, hair, and nails. My sister’s thin hair has become stronger too. The high docosahexaenoic acid content is great for cardiovascular health and brain function. My migraines have reduced significantly. I highly recommend it, but remember to consult your doctor about the dosage.
Calcium
4
Vitamin D may affect migraine frequency
We explored the link between vitamin D levels and the frequency and severity of migraines in children. In this study, we reviewed data from 171 pediatric patients diagnosed with migraines between February and December 2022.
Our findings revealed that children experiencing fewer migraines (1-3 attacks per month) had a higher median vitamin D level of 15.6 μg/L compared to those with more frequent attacks (over 3 per month), whose levels dropped to 11.9 μg/L. This suggests that adequate vitamin D levels might be associated with a lower attack frequency.
Additionally, we observed a relationship between vitamin B levels and the duration of migraine attacks. Those with shorter attack durations (2-6 hours) had higher vitamin B levels than those suffering longer attacks (12-24 hours). Furthermore, we noted that patients not receiving prophylactic treatment had higher ferritin levels compared to those who were treated. This indicates that some micronutrient deficiency might be present in patients undergoing preventive therapies.
In conclusion, our research indicates that assessing micronutrient levels, particularly vitamin D, could be beneficial for children suffering from migraines.
Our findings revealed that children experiencing fewer migraines (1-3 attacks per month) had a higher median vitamin D level of 15.6 μg/L compared to those with more frequent attacks (over 3 per month), whose levels dropped to 11.9 μg/L. This suggests that adequate vitamin D levels might be associated with a lower attack frequency.
Additionally, we observed a relationship between vitamin B levels and the duration of migraine attacks. Those with shorter attack durations (2-6 hours) had higher vitamin B levels than those suffering longer attacks (12-24 hours). Furthermore, we noted that patients not receiving prophylactic treatment had higher ferritin levels compared to those who were treated. This indicates that some micronutrient deficiency might be present in patients undergoing preventive therapies.
In conclusion, our research indicates that assessing micronutrient levels, particularly vitamin D, could be beneficial for children suffering from migraines.
9.5
Effective supplement
Most Useful Review
I used this supplement to alleviate my migraines, and it has substantially reduced their frequency.
Omega 3 Fish Oil
7
We aimed to understand how fish oil could impact migraine symptoms and blood lipids. In a study at Kuang Tian General Hospital, participants were given either fish oil or a placebo. After 12 weeks, those taking fish oil reported improved migraine frequency, duration, and pain intensity compared to the placebo group. Additionally, blood lipid levels showed significant reductions. This indicates that fish oil could be a helpful supplement for managing migraine symptoms and improving overall health.
9.5
Migraine prevention
Most Useful Review
"Mega" omega! This fish oil supplement contains polyunsaturated fatty acids like EPA and DHA, which significantly lower cholesterol and help prevent cardiovascular diseases. Omega-3 is effective for various conditions, including skin diseases and gastric ulcers. It also benefits brain function and helps reduce migraine symptoms. After starting the capsules, I noticed improvements in my migraines and overall health. I take three capsules daily with meals. If my review is helpful, please click "YES" below and check my other reviews. Wishing you good health!
B3 Niacin
7
We examined the link between dietary niacin intake and migraine occurrences by analyzing data from the National Health and Nutrition Examination Survey. This study focused on adults over 20 years old, looking specifically at their reported experiences with severe headaches and the amount of niacin they consume daily.
Among the 10,246 participants, we found that 20.1% reported having migraines. Those who had a higher intake of niacin showed a lower likelihood of experiencing migraines. For instance, compared to individuals with the lowest niacin intake, those in higher intake categories (Q2, Q3, and Q4) had significantly reduced odds of suffering from migraines. The results indicated that increasing dietary niacin had a favorable effect, suggesting an L-shaped curve relationship where the optimal intake appears to be around 21 mg per day.
This study highlighted a possible connection between niacin consumption and migraine prevention, indicating that moderate levels might play a protective role. However, it’s important to approach these findings cautiously, as they don’t establish cause and effect directly. Further research could illuminate how dietary choices might influence migraine frequency and severity.
Among the 10,246 participants, we found that 20.1% reported having migraines. Those who had a higher intake of niacin showed a lower likelihood of experiencing migraines. For instance, compared to individuals with the lowest niacin intake, those in higher intake categories (Q2, Q3, and Q4) had significantly reduced odds of suffering from migraines. The results indicated that increasing dietary niacin had a favorable effect, suggesting an L-shaped curve relationship where the optimal intake appears to be around 21 mg per day.
This study highlighted a possible connection between niacin consumption and migraine prevention, indicating that moderate levels might play a protective role. However, it’s important to approach these findings cautiously, as they don’t establish cause and effect directly. Further research could illuminate how dietary choices might influence migraine frequency and severity.
9.5
Improved health
Most Useful Review
Niacin has been excellent; I no longer experience hot flashes like I did with the usual form, which left me red and overheated. My overall health has improved, and I have noticed a decrease in migraines.
Calcium Magnesium
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
10
Migraine relief
Most Useful Review
My migraines have disappeared. I'm taking Two-Per-Day, but since it doesn't contain Cal-Mag, I'm using this as well. The migraines caused by pressure have gone. I'd like to continue taking this.
B6 Pyridoxine
8
We conducted a compelling study to find out how vitamin B6, along with other B vitamins, affects those who suffer from migraine headaches. Our research involved a structured, randomized, double-blind, placebo-controlled trial with 120 women experiencing episodic migraines. Participants were divided into groups that received either individual B vitamins like B1, B6, B12, and B9, a vitamin B complex, or a placebo for a duration of 12 weeks.
Throughout the study, we carefully monitored the frequency of headache attacks, the amount of abortive medication used, and the overall impact of migraines on daily life through questionnaires. The findings were quite promising—women taking vitamin B6, along with the other B vitamins, experienced a significant reduction in headache attacks compared to those on the placebo.
Furthermore, those receiving vitamins also reported improvements in migraine-related disability and a decrease in their reliance on abortive drugs. While our results highlight the potential benefit of B vitamins, including B6, in managing migraines, further research is essential to solidify these findings and determine the best treatment strategies.
Throughout the study, we carefully monitored the frequency of headache attacks, the amount of abortive medication used, and the overall impact of migraines on daily life through questionnaires. The findings were quite promising—women taking vitamin B6, along with the other B vitamins, experienced a significant reduction in headache attacks compared to those on the placebo.
Furthermore, those receiving vitamins also reported improvements in migraine-related disability and a decrease in their reliance on abortive drugs. While our results highlight the potential benefit of B vitamins, including B6, in managing migraines, further research is essential to solidify these findings and determine the best treatment strategies.
9.5
Very helpful treatment
Most Useful Review
Great for migraines; I find taking two of these each day very beneficial for my migraines. There are no side effects, and I have been using them for years.
Coenzyme Q10 Coq10
4
We explored the effectiveness of coenzyme Q10 as a treatment for migraines. Coenzyme Q10 has been categorized with Level C evidence in terms of its potential benefits for preventing migraines. This indicates some support for its use, but the data isn't overwhelmingly strong.
It seems that coenzyme Q10 offers low adverse effects, making it a relatively safe option for many. However, we should be mindful that the evidence isn't robust enough to label it as a primary treatment choice.
The findings suggest that while coenzyme Q10 may help some migraine sufferers, we should consider other preventative strategies as well. Our overall approach should include a range of options, especially since the strength of the evidence around coenzyme Q10 is not yet definitive.
It seems that coenzyme Q10 offers low adverse effects, making it a relatively safe option for many. However, we should be mindful that the evidence isn't robust enough to label it as a primary treatment choice.
The findings suggest that while coenzyme Q10 may help some migraine sufferers, we should consider other preventative strategies as well. Our overall approach should include a range of options, especially since the strength of the evidence around coenzyme Q10 is not yet definitive.
8.8
Migraine relief
Most Useful Review
Great product! I use this for migraine prevention and benefit from its other advantages. I combine it with CoQ10, Magnesium, B2 and butterbur—a powerful mix.
5 Htp
8
We explored how freeze-dried latex from Calotropis gigantea could help with migraine relief. This study tested both freeze-dried and sun-dried latex for their effects on behavior linked to migraine symptoms.
The freeze-dried variant showed improved properties and efficacy in reducing climbing behaviors induced by various stimuli. It appears that this form of latex interacts positively with dopamine and serotonin receptors, which play a role in migraine management.
Overall, we found that freeze-dried latex might offer a promising natural treatment option for those suffering from migraines.
The freeze-dried variant showed improved properties and efficacy in reducing climbing behaviors induced by various stimuli. It appears that this form of latex interacts positively with dopamine and serotonin receptors, which play a role in migraine management.
Overall, we found that freeze-dried latex might offer a promising natural treatment option for those suffering from migraines.
9.5
Migraine relief achieved
Most Useful Review
With 5-HTP, my mood and sleep have normalised, and I’ve experienced a disappearance of headaches and migraines. I take it with my wife. I switched from two 50mg antidepressant tablets to just one, and it suffices. My wife has eliminated her antidepressants completely! I regret not knowing about this supplement sooner—it’s truly effective! I feel more composed and my mood has vastly improved, aiding my sleep too. Please rate my review if you found it helpful!
Iron
4
We explored the potential link between iron levels in the brain and migraine attacks through a series of MRI scans. By looking at measures of brain iron content and white matter structure in a 26-year-old male migraine patient over 21 days, including both migraine-free days and days of attacks, we aimed to understand how iron might fluctuate during these episodes.
Our findings revealed interesting patterns: we observed that iron content in the brain changes during the migraine cycle. Specifically, there was an increase in white matter iron levels during migraine attacks. Alongside this, we noticed a decrease in the anisotropic properties of the brain tissue, suggesting that there might be additional changes happening in the brain's vascular system during these painful episodes.
While these results provide insights into how iron may play a role in migraine, it is important to note that the study does not confirm any direct benefits of iron treatment on migraines. Our work highlights the complexities of migraine pathology, but the direct impact of iron management remains unclear at this stage.
Our findings revealed interesting patterns: we observed that iron content in the brain changes during the migraine cycle. Specifically, there was an increase in white matter iron levels during migraine attacks. Alongside this, we noticed a decrease in the anisotropic properties of the brain tissue, suggesting that there might be additional changes happening in the brain's vascular system during these painful episodes.
While these results provide insights into how iron may play a role in migraine, it is important to note that the study does not confirm any direct benefits of iron treatment on migraines. Our work highlights the complexities of migraine pathology, but the direct impact of iron management remains unclear at this stage.
9.5
Alleviated migraines
Most Useful Review
I began taking it after being diagnosed with anaemia during a health check. With 1-2 tablets of 18mg daily, symptoms like dizziness, lightheadedness, and fatigue improved immediately. Remarkably, the migraine headaches I had suffered from diminished, and my use of painkillers reduced. It's surprising that iron intake can lead to such significant improvements in my health.
B12
7
Vitamin B12 & magnesium aid migraines
This study examined the impact of vitamin B12 and magnesium, combined with high-intensity interval training (HIIT), on women's migraine attacks.
We organized participants into four groups over two months, comparing those on supplements, those doing HIIT, and those using both approaches. We measured serum levels of a specific signaling molecule and assessed migraine severity throughout.
The results highlighted that the combination of B12, magnesium, and exercise appears to reduce migraine pain by targeting inflammation pathways.
We organized participants into four groups over two months, comparing those on supplements, those doing HIIT, and those using both approaches. We measured serum levels of a specific signaling molecule and assessed migraine severity throughout.
The results highlighted that the combination of B12, magnesium, and exercise appears to reduce migraine pain by targeting inflammation pathways.
8.8
Effective for migraines
Most Useful Review
It works well! I find this vitamin B12 beneficial for my migraines, especially considering its easy-to-take ramune form. Traditional tablet types are difficult for me to swallow. This supplement helps refresh my mind and eases neck stiffness, which contributes to my tinnitus. I particularly recommend it for anyone suffering from light sensitivity associated with migraines.
Vitamins
4
Vitamin D may affect migraine frequency
We explored the link between vitamin D levels and the frequency and severity of migraines in children. In this study, we reviewed data from 171 pediatric patients diagnosed with migraines between February and December 2022.
Our findings revealed that children experiencing fewer migraines (1-3 attacks per month) had a higher median vitamin D level of 15.6 μg/L compared to those with more frequent attacks (over 3 per month), whose levels dropped to 11.9 μg/L. This suggests that adequate vitamin D levels might be associated with a lower attack frequency.
Additionally, we observed a relationship between vitamin B levels and the duration of migraine attacks. Those with shorter attack durations (2-6 hours) had higher vitamin B levels than those suffering longer attacks (12-24 hours). Furthermore, we noted that patients not receiving prophylactic treatment had higher ferritin levels compared to those who were treated. This indicates that some micronutrient deficiency might be present in patients undergoing preventive therapies.
In conclusion, our research indicates that assessing micronutrient levels, particularly vitamin D, could be beneficial for children suffering from migraines.
Our findings revealed that children experiencing fewer migraines (1-3 attacks per month) had a higher median vitamin D level of 15.6 μg/L compared to those with more frequent attacks (over 3 per month), whose levels dropped to 11.9 μg/L. This suggests that adequate vitamin D levels might be associated with a lower attack frequency.
Additionally, we observed a relationship between vitamin B levels and the duration of migraine attacks. Those with shorter attack durations (2-6 hours) had higher vitamin B levels than those suffering longer attacks (12-24 hours). Furthermore, we noted that patients not receiving prophylactic treatment had higher ferritin levels compared to those who were treated. This indicates that some micronutrient deficiency might be present in patients undergoing preventive therapies.
In conclusion, our research indicates that assessing micronutrient levels, particularly vitamin D, could be beneficial for children suffering from migraines.
9.5
Stress reduction
Most Useful Review
This vitamin has significantly reduced my stress and anxiety, making me feel like a better person. It has also helped me get rid of my migraines and acne. It works well for me, and I would certainly recommend it to my friends and family.
Melatonin
8
We explored how melatonin can help in preventing migraines through a systematic review of randomized controlled trials. By analyzing seven studies that involved 1,283 participants, we compared the effects of melatonin to standard migraine treatments and placebo groups.
Our findings suggest that melatonin can significantly reduce both the frequency and severity of migraine attacks. However, the effectiveness seemed to depend on the dosage, and there are still questions about the best approach to take.
Beyond migraine relief, we also noted intriguing hints that melatonin might assist with weight control, indicating further avenues for research. As melatonin continues to gain popularity for various uses, including sleep disorders, its potential as a migraine preventative is a significant development worth considering.
Our findings suggest that melatonin can significantly reduce both the frequency and severity of migraine attacks. However, the effectiveness seemed to depend on the dosage, and there are still questions about the best approach to take.
Beyond migraine relief, we also noted intriguing hints that melatonin might assist with weight control, indicating further avenues for research. As melatonin continues to gain popularity for various uses, including sleep disorders, its potential as a migraine preventative is a significant development worth considering.
9.5
Effective treatment
Most Useful Review
This product is great; it significantly helps with my migraines and fibromyalgia.
Folic Acid
7
We explored how serum folate levels relate to migraines by looking at data from over 13,000 participants in a nationwide health study.
Folic acid showed a negative association with severe headaches, meaning higher levels of folate may lead to fewer migraines.
This connection was particularly strong among women, younger adults, and non-Hispanic White individuals.
However, more research is necessary to confirm these findings and further investigate the influence of folate on migraine prevention.
Folic acid showed a negative association with severe headaches, meaning higher levels of folate may lead to fewer migraines.
This connection was particularly strong among women, younger adults, and non-Hispanic White individuals.
However, more research is necessary to confirm these findings and further investigate the influence of folate on migraine prevention.
10
Migraine relief
Most Useful Review
I take inositol, 4000mg daily, with my husband, and the migraines that tormented me for six years have vanished. I'm amazed by this response to the medication; it has given me a surge of energy. I'm delighted I eventually tried it for my migraines, although it was originally recommended by my gynecologist for pregnancy planning.
Ginkgo Biloba
9.5
Migraine relief
Most Useful Review
Perfectly manages my migraines while improving memory, normalising blood pressure, and adding strength and efficiency. I highly recommend it.
9.5
Migraine management
Most Useful Review
Taking Ginkgo Biloba improves blood circulation in my brain, reduces migraines, enhances memory, and lowers blood pressure. I recommend adhering to dosage guidelines.
Selenium
9.5
Migraine relief achieved
Most Useful Review
Fine! I appreciated Selenium from this company immensely; my family and I enjoy it together. Alongside, we take Omega and D3 with K2, as well as Yodomarin and Aevit from Russian manufacturers. Regarding efficacy, I was utterly exhausted for a long period, lying in bed without the strength or motivation for daily chores. Now, I wake up refreshed and am active throughout the day! After suffering from migraines for the past four years, particularly with weather changes, I found relief once I introduced Selenium and D3K2. I'm also pleased to say hangovers are a thing of the past; I wake up fresher and more cheerful than ever. I highly recommend staying active and healthy!
9.5
Migraine improves significantly
Most Useful Review
GREAT! It normalises sleep with consistent intake of two capsules. It improves my migraines significantly. Special effects ensue, and with extra magnesium, migraines fade away in a couple of hours. Previously, they would incapacitate me for half a day. The frequency has also decreased. If I take magnesium regularly, PMS and menstruation are much easier; I remain calm and can get through the first day without painkillers. Chronic nasopharyngeal pain hardly worsens, but it's hard to attribute this solely to magnesium since I take omega-3, serrapeptase, and resveratrol as well. Nonetheless, I've really observed the effects of collagen intake too. Surprising, but true. No allergies or stomach issues; the quality is excellent, and ingredients are natural.
Nattokinase
8.8
Prevents strokes
Most Useful Review
Nattokinase is a long-term health investment that gently thins the blood, protecting against cholesterol plaques and clots. It also alleviates migraines, which I can attest to. We take it as a family, and my elderly parents have seen a noticeable improvement. We’re being proactive with our health to reduce the risk of strokes or heart attacks.
9.5
Migraine relief
Most Useful Review
Nattokinase has been my lifesaver for frequent migraines! It thins the blood, which might be why it helps. I struggled with headaches, especially during weather changes, but now I've found relief. I highly recommend it to anyone who suffers from migraines.
Childrens Herbs
9.5
Helps migraines
Most Useful Review
This has genuinely helped with my migraines. After trying various medications to no avail, I found relief with this product. Initially, I took it for children's colds, but it works wonders for my migraines, significantly reducing headaches within an hour.
9.5
Improved migraine management
Most Useful Review
This product has transformed my migraine management. Regular intake of two capsules not only helps me sleep but also alleviates my migraines within a couple of hours. I used to suffer for half a day, but with magnesium and this treatment, the frequency has reduced, enhancing my overall health.
Vitamin Bs
9.5
Boosts energy and mood
Most Useful Review
This is my favourite vitamin. It alleviates migraines, boosts energy, and ensures a good night's sleep. I've been taking B1 for nearly a year, helping to relieve fatigue and weakness from stress. I take it regularly, even instead of coffee, to combat migraines, especially after stressful days.
8.8
Effective for migraines
Most Useful Review
Muscle pains and cramps at night have vanished. My migraines have become much less painful, and I've lost my irritability. I followed my doctor's prescription, alternating it with magnesium, and I believe that contributed to my improvement. Was my review helpful?
Vitamin B Complex
9.5
Migraine reduction
Most Useful Review
Trims migraine attacks. This has been my salvation! As a doctor, I initially doubted that migraine is a metabolic disease. However, the effect was significant: my episodes reduced significantly. When I tried to stop taking this complex, the migraines returned. With this supplement, I use only 1 pack of triptans monthly, compared to 6-7 packs without it.
9.5
Blocks migraine attacks
Most Useful Review
Taking this supplement daily, I noticed my skin has improved, and notably, it has prevented my monthly migraine attacks linked to PMS. Normally, I suffer severe headaches that only vomiting alleviates, but after two months on this supplement, I was amazed to experience no migraines this time. I even gave a capsule to my mother when she had a headache, and after about an hour, she felt relief. Unlike painkillers, which only harm, this supplement appears to benefit the body and allow the mind some rest.
Potassium
9.5
Migraines improved
Most Useful Review
I bought this product to balance my magnesium for migraines with potassium. Since using it, I’ve seen improvement in the numbness in my feet and fluid retention. I had no shipping issues to Australia.
9.5
Migraine frequency reduced
Most Useful Review
This product helps normalise sleep with regular intake. It improves my migraines, allowing me to manage them more easily. Since taking magnesium regularly, my PMS and menstrual pain have also significantly improved, and chronic nasopharyngeal pain is less severe. I’ve noticed benefits from taking collagen too. Overall, no allergies or stomach issues occurred; the quality is excellent.
Fiber
9.5
Migraine relief
Most Useful Review
Perfectly manages my migraines while improving memory, normalising blood pressure, and adding strength and efficiency. I highly recommend it.
8.8
Helps with migraine
Most Useful Review
Excellent vitamin B2! It aids recovery from viral infections, calms the nervous system, and assists in migraine relief. One capsule contains 100 mg of vegetarian B2, and I take it with food daily. The symptoms of deficiency include dry eyes and irritability. Solgar's quality is impressive, and I've repeatedly found it beneficial.
Vitamin E
8.8
Reduced migraine frequency
Most Useful Review
Very good cost performance! I’m taking this supplement alongside my girlfriend. Vitamin E is fat-soluble and difficult to overdose on, with just one tablet needed each day, making it easy to take. I've noticed it’s effective; my girlfriend used to suffer from severe migraines, but since she started this product, the frequency of her migraines has surprisingly decreased. I plan to continue using it!
9.5
Decreased migraine frequency
Most Useful Review
It incorporates the Fujikawa method. Since I started taking vitamin E, my migraine headaches have significantly decreased. There are many types of E, so I chose this one thinking NOW would assure quality. I currently take 3 capsules a day, cutting them with scissors to consume the oil inside.
Ubiquinol Coq10
10
No migraines since
Most Useful Review
After using Coenzyme Q10, I switched to reduced ubiquinol for better efficacy. Previously suffering from migraines, since I began taking ubiquinol, I haven't experienced any migraines.
9.5
Recommended for migraines
Most Useful Review
An excellent supplement! I was advised by my neurologist to take this specific dosage for heart health, youth, nervous system support, and migraines. Ubiquinol is the most easily absorbed coenzyme form.
Rutin
8.8
Effective alternative
Most Useful Review
Helped my mum with her migraine headaches. This product works brilliantly, much better than the pharmacy alternatives.
10
Preventive solution
Most Useful Review
A miraculous drug! Having suffered from migraines related to my blood vessels for a long time, I regularly took pills whenever the pain started. However, after using this for six months, I haven’t had a headache, even during bad weather. It has no taste and is comfortable to take, and I think it could be beneficial for prevention. I’m absolutely delighted and have reordered.
Multivitamins
8.3
Migraine pain relief
Most Useful Review
My migraine has improved! Since I started taking this, the pain has significantly changed. Previously ineffective analgesics are now nearly useful, perhaps due to better blood flow.
9.5
Migraine-free after weeks
Most Useful Review
A great product! After a week of taking it, my migraines have ceased. Previously, they occurred almost daily. My skin and hair have improved as well. I take two capsules daily alongside nursing vitamins, and I haven’t noticed any side effects.
Inositol
10
Migraine-free experience
Most Useful Review
I absolutely love this product! I suffer from frequent migraines, often weekly, which can last for days despite medication. Remarkably, after taking this for over six months, I haven't experienced any headaches! I started noticing benefits after a few days of consistent use, adhering to the recommended two capsules daily. The capsules are a manageable size without any unpleasant aftertaste. The product arrived well-packaged and in excellent condition. Thank you for creating such a quality product, and I look forward to reordering soon!
9.5
Reduced migraine frequency
Most Useful Review
The neurologist prescribed medication for increased intracranial pressure for my adult son. In our pharmacy, tablets for 28 days cost 1400 rubles. I later found an analogue on iHerb, obtaining pills for three months for 500 rubles. I'm delighted! This excellent medication significantly reduces the frequency of my migraine attacks and seems particularly effective for those suffering from increased intracranial pressure.
Peppermint Oil
9.5
Relieves migraines
Most Useful Review
This essential oil from Now Foods has an excellent fragrant mint aroma. It invigorates and provides a cooling effect on the skin. I use it in diffusers, hair masks, and even in cleaning solutions. It effectively relieves migraines when applied to the temples, and when diluted with a carrier oil, it has multiple uses. I love incorporating this oil into my daily routine.
9.5
Helps with migraines
Most Useful Review
This is my favourite essential oil. It enhances blood circulation on my scalp for hair growth and soothes my temples during a migraine. I also use it for cramps and find its uplifting fragrance incredibly beneficial for my well-being. The NOW brand offers great quality at an affordable price, which is why I keep purchasing it regularly.
L Ornithine
9.5
Neurologist recommendation
Most Useful Review
Super! Prescribed by my neurologist as part of the complex therapy for migraine due to its ability to lower ammonia levels in the blood. I can confidently say that this medication is effective; I highly recommend it.
8.8
Relief from symptoms
Most Useful Review
I have been using it for about a month and am satisfied with the results. It helps to eliminate ammonia from my body, and I've noticed that drowsiness, lethargy, bad mood, and headaches have disappeared. I recommend it for those with migraines as it helped me considerably. Please mark my review as "helpful." Thank you.
Cat Claw
NOW Foods Cat's Claw
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
8.8
Reduced headaches
Most Useful Review
I repeatedly experienced migraine headaches and scotomata. However, since I began taking this supplement a few years ago, my flash scotomas have vanished. I can now manage headaches with regular painkillers. If you're facing similar issues, I recommend giving it a try.
7.5
Fewer migraines
Most Useful Review
I have been enduring migraines for quite some time. After starting this treatment, I've noticed a reduction in the frequency of my headaches, which seems to improve with prolonged use.
Acetyl L Carnitine
10
Migraine relief
Most Useful Review
Excellent product; I'm very pleased with my purchase. These capsules are easy to swallow without tasting them. Previously, I used a brand with large, chalky, and odorous pills. While these capsules do have a slight smell, you can take them before noticing it, and they are far less pungent than the last brand. NAC has numerous health benefits (look up NAC and glycine!), but the most significant for me is its apparent elimination of my near migraine-level headaches. Good packaging.
8.8
Notable improvements
Most Useful Review
We frequently host the entire family. Acetyl-L-Carnitine is the best form for absorption. A teenager with disabilities and migraines takes this supplement along with a basic protocol, and the improvements are noticeable over the year.
Oregano Oil Supplements
8.8
Effective for migraines
Most Useful Review
This is such an underrated herb. I use it for everything, from headaches and migraines to colds, and I can't do without it.
9.5
Migraines alleviated
Most Useful Review
It is excellent for relieving migraines and sinus issues.
Evening Primrose Oil
9.5
No improvement noted
Most Useful Review
I tried for several months to alleviate my migraine, but sadly, it didn’t help me at all :(
7.5
Migraine nuisance reduced
Most Useful Review
The oil helps to regulate hormone levels and improve the functioning of the nervous system, providing relief from PMS and migraines. It restores hormonal balance and has a healing effect on breast tissue.
Spirulina
9.5
Migraines relief
Most Useful Review
After reading numerous praises, I added spirulina to my diet. Remarkably, my persistent migraines disappeared, and I also felt more energetic with notable improvements in my complexion.
8.8
Fewer migraines
Most Useful Review
This is high-quality spirulina. I take it to alleviate my sinus issues, and since I started using it, my migraines have noticeably reduced, which is a significant benefit for me. The effects began after the third week.